Name: _____________________ Pd.: ____ Section 11.1 The Work of Gregor Mendel (p. 308-312) 1. What is fertilization? __________________________________________________________ 2. What did Mendel conclude determines biological inheritance? __________________________________________________________ 3. What are dominant alleles? __________________________________________________________ 4. What are recessive alleles? __________________________________________________________ 5. Why were true-breeding pea plants important for Mendel’s experiments? __________________________________________________________ 6. Explain how Mendel kept his pea plants from self-pollinating. __________________________________________________________ __________________________________________________________ 7. What is segregation? __________________________________________________________ 8. Compare the alleles between the P generation and the F2 generation? __________________________________________________________ 9. Looking at the F2 generation, what evidence did Mendel use to explain how segregation occurs? __________________________________________________________ 10.Cross two pea plants and get both tall and short offspring. a. What could have been the genotypes of the two original plants? __________________________________________________________ b. What genotype could not have been present in one of the parents? __________________________________________________________ 1 Name: _____________________ Pd.: ____ Cow Problem: In a certain type of cattle, hornless is dominant to horned cattle. A bull was mated to 4 heifers. Heifer #1 was hornless and had a horned calf (A). Heifer #2 was horned and had a horned calf (B). Heifer #3 was horned and had a hornless calf (C). Heifer #4 was hornless and had a hornless calf (D) and a horned calf (E). What is the one genotype and phenotype of the bull? List the genotype and phenotype of all 4 cows. Show a Punnett square for each cross, circling the offspring referenced in the above scenario. Genotype Phenotype Bull Heifer #1 Heifer #2 Heifer #3 Heifer #4 Genotype Phenotype N/A N/A Calf A Calf B Calf C Calf D Calf E Punnet Squares: Heifer #1 Heifer #2 Heifer #3 Heifer #4 2 Name: _____________________ Pd.: ____ Section 11.2 Applying Mendel’s Principles (p. 313-318) 1. What is probability? __________________________________________________________ 2. What does homozygous mean? __________________________________________________________ 3. What does heterozygous mean? __________________________________________________________ 4. What is the difference between genotype and phenotype? __________________________________________________________ __________________________________________________________ 5. If T represents the allele for tall and t represents the allele for short and you cross a TT plant with a Tt plant: a. Which parent is homozygous dominant? _________________________________ b. Which parent is heterozygous? __________________________________________ c. What is (are) the genotype(s) of the offspring? ___________________________ d. What is (are) the phenotype(s) of the offspring? __________________________ 6. How are Punnett squares used to predict the outcomes of genetic crosses? __________________________________________________________ __________________________________________________________ 7. Why is the fruit fly an ideal organism? __________________________________________________________ 8. List AND describe the four principles of genetics that Mendel discovered in his experiments. a. ______________________________________________________ ______________________________________________________ b. ______________________________________________________ ______________________________________________________ c. ______________________________________________________ ______________________________________________________ d. ______________________________________________________ ______________________________________________________ 3 Name: _____________________ Pd.: ____ Section 11.3 Other Patterns of Inheritance (p. 319-321) 1. What does incomplete dominance mean? __________________________________________________________ a. Give an example: _______________________________________________________ 2. What is codominance? __________________________________________________________ a. Give an example: _______________________________________________________ 3. A pink-flowered Mirabilis plant (RW) is crossed with a white-flowered Mirabilis plant (WW). What is the chance that a seed from this corss will produce a red-flowered plant? __________________________________________________________ Show the punnett square you used to determine your answer: 4. Why can multiple alleles result in many different phenotypes for a trait? __________________________________________________________ 5. What is the difference between multiple alleles and polygenic traits? __________________________________________________________ __________________________________________________________ 6. Explain why an organism’s characteristics are not only determined by its genes. __________________________________________________________ __________________________________________________________ __________________________________________________________ 7. What might be the result of an exceptionally hot spring on wing pigmentation in the western white butterfly? __________________________________________________________ 4 Name: _____________________ Pd.: ____ Section 14.1 Human Chromosomes (p. 392-397) 1. What is a genome? __________________________________________________________ 2. What is a karyotype? __________________________________________________________ 3. What are autosomes? __________________________________________________________ a. How are they different from sex chromosomes? __________________________________________________________ 4. What determines whether a person is male or female? __________________________________________________________ 5. Explain how sex-linked traits are inherited. __________________________________________________________ __________________________________________________________ 6. If a woman with blood type O and a man with blood type AB have children, what are the children’s possible genotypes? __________________________________________________________ Show the punnett square you used to determine your answer: 7. What does a pedigree show? __________________________________________________________ __________________________________________________________ 8. Why would it not be likely for the Y chromosome to contain genes necessary for survival? __________________________________________________________ 5 Name: _____________________ Pd.: ____ Section 14.3 Studying the Human Genome (p. 402-409) 1. How many base pairs does the smallest human chromosome contain? ________________________________________________________ 2. What do restriction enzymes do? __________________________________________________________ __________________________________________________________ 3. Describe the THREE techniques that are used to study human DNA. a. Cutting DNA: ______________________________________________________ b. Separating DNA: ______________________________________________________ c. Reading DNA: ______________________________________________________ 4. Why does DNA move toward the positive end of the gel during gel electrophoresis? __________________________________________________________ 5. What is the Human Genome Project? __________________________________________________________ 6. How is shotgun sequencing similar to doing a jigsaw puzzle? __________________________________________________________ 7. What is bioinformatics? __________________________________________________________ 8. How might the project be used to benefit humankind? __________________________________________________________ __________________________________________________________ 9. What potential problems might it create? __________________________________________________________ __________________________________________________________ 6 Name: _____________________ Pd.: ____ Section 15.2 Recombinant DNA (p. 421-318) 1. Why would a scientist want to know the sequence of a DNA molecule? __________________________________________________________ 2. What is the purpose of using the polymerase chain reaction? __________________________________________________________ 3. List the steps of the polymerase chain reaction. a. ______________________________________________________ b. ______________________________________________________ c. ______________________________________________________ d. ______________________________________________________ 4. How do scientists use recombinant DNA? __________________________________________________________ 5. What is a plasmid? __________________________________________________________ a. In what organisms are plasmids found? __________________________________________________________ 6. What is a genetic marker? __________________________________________________________ 7. What is a transgenic organism? __________________________________________________________ 8. Bacteria and humans are different organisms. Why is it possible to combine their DNA and use bacteria to make a human protein? __________________________________________________________ __________________________________________________________ 9. Compare the transformation of a plant cell with the transformation of an animal cell. __________________________________________________________ __________________________________________________________ __________________________________________________________ 10.What is a clone? __________________________________________________________ 11. Using figure 15-2, describe the process of creating an animal clone. __________________________________________________________ __________________________________________________________ __________________________________________________________ __________________________________________________________ 7