Kollokvier og Projektoplæg 1. Fredag d. 2.9. Peter Arctander: Introduktion til ME05 En kort gennemgang af projekterne. Sammensætning af grupper og valg af projekter. Seminar: Hans Siegismund og Peter Arctander: Afdelingens projekter med store planteædere i Afrika. 2. Fredag d. 9.9. Studenteroplæg; Majken Sønderholm Muwanika,V.B., S. Nyakaana, H.R. Siegismund and P. Arctander 2003.Phylogeography and population structure of the common warthog (Phacochoerus africanus) inferred from variation in mitochondrial DNA sequences and microsatellite loci. Heredity 91: 361-372. Studenteroplæg; Janni Albertsen Seielstad, M.T., E. Minch & L. Cavalli-Sforza. 1998 Genetic evidence for a higher female migration rate in humans. Nature Genetics 20: 278-280. Wilder, J.A., S.B. Kingan, Z. Mobasher, M. M. Pilkington & M.F. Hammer. 2004 Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males. Nature Genetics 36: 1122-1125. Studenteroplæg; Daniel Cappiello N.A. Rosenberg, J.K. Pritchard, J.L. Weber, H.M. Cann, K.K. Kidd, L.A. Zhivotovsky, M.W. Feldman. 2002 Genetic Structure of Human Populations. Science 298: 2381-2385. 3. Fredag d. 16.9. Studenteroplæg (2 studenter) Fylogenetisk rekonstruktion. Graur, D. & W.H. Li. 2000 Chapter 5, Molecular Phylogenetics. Studenteroplæg HIV evolution. Korber, B., M. Muldoon, J. Theiler, F. Gao, R. Gupta, A. Lapedes, B. H. Hahn, S. Wolinsky, and T. Bhattacharya, 2000 Timing the ancestor of the HIV-1 pandemic strains. Science 288: 1789-1796. Studenteroplæg HIV. Ou, C.Y. et al. 1992 Molecular Epidemiology of HIV Transmission in a Dental Practice. Science. 256:1165-1171 4. Fredag d. 23.9. Studenteroplæg; Jacob Guenther Schmidt Lysozym. Irwin, D. M., Prager, E. M. and Wilson, A. C. (1992): Evolutionary genetics of ruminant lysozymes. Animal Genetics, 23: 157-166. Ingen pdf Messier, W. and Stewart, C. B. (1997): Episodic adaptive evolution of primate lysozymes. Nature, 385: 151-154 Lærebog f.eks.: Gen-dynamik i populationer (pp 39-65) Studenteroplæg; Louise Hebert Halle UV-syn. Shi, Y. and Yokohama, S. 2003: Molecular Analysis of the evolutionary significanse of ultraviolet vision in vertebrates. PNAS 100:8308-8313. Zhang, J. 2003: Paleomolecular biology unravels the evolutionary mystery of vertebrate UV vision. PNAS 100.8045-8047. Studenteroplæg; Christian Roar Andersen Weile psi gær prion, True, H., Lindquist, S., 2004. Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits. Nature. 431:184-7 Epub August 15. Alain E. Bussard (2005): A scientific revolution? The prion anomaly may challenge the central dogma of molecular biology. EMBO Reports 6:691-695. Hsp70 hos Drosophila. Christine Queitsch, Todd A. Sangster & Susan Lindquist (2002): Hsp90 as a capacitor of phenotypic variation. Nature 417: 618-624. 5. Fredag d. 30.9. Studenteroplæg; Anders Kofoed Genomisk output. Jill Cheng, Philipp Kapranov, et al. (2005): Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution. Science 308:1149-1154. Studenteroplæg; Kirsten Ellegaard Splejsning. Graveley, B. R. (2001): Alternative splicing: increasing diversity in the proteomic world. Trends in Genetics, 17(2): 100-107. Studenteroplæg; Casper RNA-editing. Maas, S. and Rich, A. (2000): Changing genetic information through RNA editing. BioEssays 22(9): 790-802 Stuart, K., Panigrahi, AK 2002: RNA editing: complexity and complications. Molecular Microbiology 45:591-596 Studenteroplæg; Rasmus Heller Hard wired – soft wired. Herbert, A. & Rich, A., 1999: RNA processing and the evolution of eukaryotes. Nature Genetics 21: 265-269. 6. Fredag d. 7.10. Studenteroplæg; ncRNA regulerende netværk. Mattick, JS 2004: RNA regulation: a new genetics? Nature Reviews Genetics 5:316-323. Studenteroplæg; Tom Manczak miRNA. Novina, CD & Sharp, PA, 2004: The RNAi revolution. Nature 430: 161-164 Studenteroplæg; Dorte Bek miRNA. Erno Wienholds, Wigard P. Kloosterman, Eric Miska, Ezequiel Alvarez-Saavedra, Eugene Berezikov, Ewart de Bruijn, H. Robert Horvitz, Sakari Kauppinen, Ronald H. A. Plasterk (2005): MicroRNA Expression in Zebrafish Embryonic Development. www.sciencexpress.org /26 May 2005 / Page 1/ 10.1126/science.1114519 Studenteroplæg; Christina Abel ultra-konservative elementer. Gill Bejerano, Michael Pheasant, Igor Makunin, Stuart Stephen, W. James Kent, John S. Mattick, David Haussler (2004): Ultraconserved Elements in the Human Genome. Science 304: 1321-1326. 7. Fredag d. 14.10. Studenteroplæg; Elsi Sinikka Kauppinen Retrotransposition, overblik: T. Mourier (2005): Reverse transcription in genome evolution. Cytogenetic and Genome Research 2005, Vol. 110, No. 1-4: 56-62 Studenteroplæg; Dennis Persson TE og genomer: J. Brosius (2005): Echoes from the past – are we still in an RNP world? Cytogenet Genome Res 110:8–24 (2005) TE og mosaicism. Moutori et al. (2005); Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature 435:903-910. Studenteroplæg; Jesper Phillip Christensen Aagaard TE RNA-edit og splejsning, Alu og Line. A. Athanasiadis, A. Rich, S. Maas (2004): Widespread A-to-I RNA Editing of AluContaining mRNAs in the Human Transcriptome. Plos 2:e391 D.Y. Kim et al. (2004): Widespread RNA Editing of Embedded Alu Elements in the Human Transcriptome. Genome Research 14:1719–1725. Projekt oplæg, hold x 8. Fredag d. 28.10. Projekt oplæg, hold Projekt oplæg, hold Projekt oplæg, hold Projekt oplæg, hold x x x x 9. Fredag d. 4.11 Projekt oplæg, hold x Projekt oplæg, hold x Projekt oplæg, hold x Afslutning og evaluering Projektarbejde og seminarer 1. Tirsdag d. 6.9. Seminar 2. Tirsdag d. 13.9. Seminar: Rasmus Nielsen 3. Tirsdag d. 20.9. Seminar: Jon Bollback: experimental virus evolution 4. Tirsdag d. 27.9. Seminar: Tobias Mourier: Plasmodium RNA genes Paul Gardner: Affymetrix tiling arrays 5. Tirsdag d. 4.10. Seminar: Morten Lindow: Finding miRNAs 6. Tirsdag d. 11.10. • Seminar : Jonas Bin-Laden: Introduktion til fossilt DNA 7. Tirsdag d. 25.10. Seminar 8. Tirsdag d. 1.11. Afslutning og evaluering Seminarer Dato ikke fastlagt 1. Anders Krogh: bioinformatik 2. Eline Lorenzen: Impale populations- og bevaringsgenetik 3. Mads Hedegaard 4. Henrik Glenner 5. Duur K. Aanen