DATA SHEET NO
THE UNIVERSITY OF BIRMINGHAM
School of Biological Sciences
Name of
Supervisor
Assessment Number
Publicover
Supervisor's
Signature
Note
Date of Assessment
13.10.98
Guidance on making an assessment is given in Making a Chemical Hazard and Risk Assessment (USP/90/CHRA/16).
Guidance is also available from Notes on Completing the Chemical Hazard and Risk Assessment Form.
A Word for Windows document template for this form is available from the School Safety Officer.
When completed, a copy of this form must be lodged with The School Safety Officer Mr P G Dearn
1
LOCATION OF THE WORK ACTIVITY
2
PERSONS WHO MAY BE AT RISK
List names where possible
W130
S Publicover and PGs (Y Gu, J Brown, E Punt, C Harper)
3
ACTIVITY ASSESSED
4
MATERIALS INVOLVED
Culture of primary bone cells in presence of MAP4
Attach copies of data sheet(s)
NAME
MAP4
5
1758
HAZARD
toxic
RISK PHRASES
DATASHEETNO
toxic if swallowed or absorbed through skin
INTENDED USE
Give brief details and attach protocol/instructions
MAP4 will be added M concentrations to cell culture media during glutamate stimulation.(10-20 ml)
6
RISKS to HEALTH and SAFETY from INTENDED USE
From personal exposure or hazardous reactions. Refer to OELs, flash points, etc., as appropriate
Negligible due to the low concentrations and small volumes in use
7
CONCLUSIONS ABOUT RISKS
Is level of risk acceptable? Can risk be prevented or reduced by change of substance/procedure? Are control measures necessary?
Risk is minimal and acceptable
8
CONTROL MEASURES
Additional to Good Chemical Practice. Specify type or performance of control measure
Good chemical practice. Use of lab coat and plasic gloves when handling. Careful labelling of all solutions.
9
INSTRUCTION/TRAINING
Specify course(s) and/or special arrangements.
Nothing beyond care in weighing and handling which is already practiced with all drugs in the laboratory
10
MONITORING
Performance of control measures,
Regular chaecks on fridge and on sinks to monitor disposal.
Personal exposure
Health Surveillance
None
None
11
WASTE DISPOSAL PROCEDURE
Disposed of with waste cell culture media (after chloros treatment)
12
REVIEW
Enter the date or circumstances for review of assessment (maximum review interval 5 years)
Use of geatly increased volume or concentration
13
EMERGENCY ACTION AND CONTACTS WHERE NECESSARY
TO CONTROL HAZARDS
Mop up spills
TO PROTECT PERSONNEL
Not necessary
To stabilize situation eg spread absorbant on liquid spill; eliminate sources of ignition, etc.
CONTACT
Evacuation, protection for personnel involved in clean-up, Special First Aid
TO RENDER SITE OF EMERGENCY SAFE
Not necessary
PHONE Ex. 6560
CONTACT
Clean-up/decontamination
PHONE Ex. 6560
CONTACT
PHONE Ex. 6560