Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 Order Set: Admission for Ischemic Stroke for Patient not Receiving tPA This order set pertains to those admission orders from ER or direct admit to the hospital for patients 18 years or older who present with symptoms of recent neurologic dysfunction suggestive of brain ischemia. These orders exclude patients with TIA, hemorrhagic stroke or ischemic stroke receiving thourombolytic therapy. Legend: Open boxes are orders that a clinician will need to order by checking the box. Pre-checked boxes are those orders with strong supporting evidence and/or regulatory requirements that mandate documentation rationale for deviation from standard if not done. Patient Information (Two are required.) Last Name: First Name: Date of Birth: ___/___/_____ Patient’s age: ID #: Admitting Data Admit to: ICU bed Step down: with telemetry Stroke/neurology: with telemetry Other without telemetry without telemetry Attending physician: Primary physician: Contact primary care physician Notify stroke nurse clinicians Notify stroke research team if that patient is eligible for stroke research Diagnosis Admitting Dx: Acute ischemic infarct Other Secondary Dx: Patient excluded from thourombolytic therapy (tPA) due to: Time from onset contraindications Clinical contraindications Laboratory contraindications Radiologic contraindications Condition Stable Code Status Full code Unstable Patient history contraindications Other Other DNR/DNI Unknown Copyright 2012 by Institute for Clinical Systems Improvement www.icsi.org 1 Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 Vitals Telemetry/monitor for first 24 hours: Notify physician if EKG or telemetry is suspicious for atrial fibrillation Telemetry/monitor for 48 hours Notify physician if EKG or telemetry is suspicious for atrial fibrillation Vital signs (BP, heart rate and O2 sat) and non-NIHSS neuro check: every hour for 4 hours then every 4 hours while awake (if stable) Notify physician for antihypertensives required for blood pressure greater than 220 mmHg systolic or 120 mmHg diastolic Notify physician for antihypertensives required for blood pressure greater than arterial pressure greater than mmHg after the first 24 hours. mmHg systolic or mean Notify physician if blood pressure is less than mmHg or systolic mmHg diastolic Orthostatic blood pressure check and heart rate before patient is mobilized from bed (lying, sitting, and standing if patient is able to stand) Weight on admission and then every day Input/output for 24 hours or Temperature every 4 hours for 48 hours while awake Temp every shift after 48 hours while awake if temp is normal Notify physician if temp greater than 101.3oF (38.5oC) Fall risk assessment Activity Bed rest for hours with turns every hours In chair twice daily beginning as soon as no fluctuating neurologic status Up with assistance Up ad lib Allergies/Adverse Drug Reactions None Yes, Name: Type of reaction: Type of reaction: Type of reaction: Nursing Orders Keep patient with nothing by mouth until/unless patient passes nursing bedside swallowing evaluation Bedside glucose test now (if not done in ER) O2 saturation monitor until O2 saturations remains stable. Check with vitals Oxygen 2 liters per minute by nasal cannula if O2 saturations less than 94%. Titrate O2 to maintain www.icsi.org Institute for Clinical Systems Improvement 2 Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 saturation greater than or equal to 94% Notify physician if O2 saturation is less than 91% Cough and deep breath every hour while awake Incentive spirometer every hours while awake Straight catheter Every shift if no void 300 cc by bladder scan Notify physician if 2 consecutive straight catheterizations needed for no void Bedside glucose checks every 4 hours for 24 hours Notify physician if glucose greater than 180 mg/dL AND no sliding scale ordered Bedside glucose checks 4 times a day after 24 hours, e.g., ac and hs. Discontinue glucose checks if glucose stable and less than 150 mg/dL Nursing bedside swallowing evaluation – contact speech therapy for formal evaluation if fail any of the below: - More than one swallow to empty mouth - Wet voice after swallow - Drooling - Cough on water Soft care mattress (if nursing assessment identifies risk of skin breakdown) Fall alert (if nursing assessment identifies risk of falling) Heel protection (if nursing assessment identifies risk of skin breakdown) Diet (If patient fails bedside swallow screen, keep patient with nothing by mouth until speech therapy formal evaluation ) Nothing by mouth Diet as recommended by speech therapist IVs (Avoid use of dextrose 5% in water, especially if hyperglycemic and avoid hypotonic solutions) Establish IV saline lock with flush every 12 hours 0.9% NaCl in water at mL/hour at mL/hour Dextrose 25 mL every 15 minutes as needed to maintain glucose level above 70 mg/dL Sedative/Symptom Medication (Note: No oral medications until/unless patient passes a bedside swallow screen) Acetaminophen 650 mg maximum cumulative 4 grams per 24 hours by mouth or rectal suppository every four hours as needed if Temperature greater than 99.5oF (37.5oC) OR pain Sedative mg by mouth at bedtime as needed Bowel care: Docusate sodium 100 mg by mouth every 12 hours as scheduled for constipation Magnesium hydroxide (Milk of Magnesia®) 30 mL (30-60 mL) by mouth daily as needed for constipation (maximum dose 60 mL per 24 hours) Bisacodyl 10 mg suppository. Repeat in 1 hour if inadequate results as needed for constipation Fleets enema as needed for constipation www.icsi.org Institute for Clinical Systems Improvement 3 Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 Medications Pharmacologic VTE Prophylaxis (Aspirin is not recommended as monotherapy for VTE prophylaxis.) Dalteparin 5,000 units subcutaneous every 24 hours beginning at admission (Use low-dose unfractionated heparin for creatinine clearance [CRCL] less than 30 mL/min.) Initiate the following if dalteparin ordered: - Platelet count and hemoglobin every other day beginning on day two - Discontinue dalteparin if platelet count drops 50% or more from baseline value and notify physician - Initiate patient education - Notify physician if bleeding occurs Enoxaparin 40 mg subcutaneous every 24 hours beginning at admission (Use unfractionated heparin for CRCL less than 30 mL/min.) Initiate the following if enoxaparin ordered: - Platelet count and hemoglobin every other day beginning day two - Discontinue enoxaparin if platelet count drops 50% or more from baseline value and notify physician - Initiate patient education - Notify physician if bleeding occurs Unfractionated heparin 5,000 units subcutaneous every 8 hours beginning at admission. Initiate the following if unfractionated heparin ordered: - Platelet count and hemoglobin every other day beginning day two - Discontinue unfractionated heparin if platelet count drops 50% or more from baseline value and notify physician - Initiate patient education - Notify physician if bleeding occurs (Alternative pharmacologic VTE prophylaxis program) Mechanical VTE Prophylaxis Pneumatic compression: Knee-high Thigh-high Foot boots Early Secondary Stroke Prevention (Document contraindications if not given. Withhold ibuprofen for 30 minutes after aspirin administration.) Aspirin mg (160-325 mg) immediately By mouth Aspirin mg (160-325 mg) daily by mouth Coated Coated Buffered mg by mouth every Buffered Rectal suppository Rectal suppository Acute Post Stroke Hypertension Management (Consider IV regimen if swallow is questionable.) BP less than 220/120 mmHg Observe with vitals. BP systolic greater than 220 OR diastolic greater than 120 mmHg or mean arterial pressure greater than 130 mmHg for the first 24 to 48 hours Labetalol 10-20 mg IV over 2 minutes. May repeat or double every 10 minutes to achieve 10-15% reduction in blood pressure (maximum dose 300 mg per 24 hours). Nicardipine 5 mg/hour IV infusion initial dose; titrate up 2.5 mg/hour every 5 min. to 15 mg/hour. to achieve 15% reduction in blood pressure (maximum 15 mg/hour). www.icsi.org Institute for Clinical Systems Improvement 4 Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 BP diastolic greater than 140 mmHg Labetalol mg (100-200 mg) by mouth initially and mg every two hours as needed to maintain BP less than mmHg (max. 800 mg per 24 hours) Labetalol 10 mg IV over 2 minutes. May repeat with 40-80 mg IV every 10-20 minutes as needed to maintain BP less than mmHg (maximum cumulative dose 300 mg per 24 hours) Nitroprusside 0.5 mcg/kg/minute IV infusion initial dose with continuous BP monitoring. Notify physician if blood pressure not controlled with medication mg every at hours as needed to maintain BP mmHg Notify physician if systolic BP greater than 220 or diastolic BP greater than 120 (MAP greater than 130) with medication. Notify physician if systolic BP greater than medication. or diastolic BP greater than (MAP greater than Management of Prehospital Hypertension Medication Program (Note: No oral medications until/unless patient passes a bedside swallow screen) Hold all prehospital antihypertensive drugs first 24 hours Give half doses of prehospital antihypertensive drugs first 24 hours, i.e., Give full doses of prehospital antihypertensive drugs first 24 hours, i.e., Other program for prehospital antihypertensive drugs first 24 hours, i.e., Give full doses of prehospital antihypertensive agents after 24 hours Ask physician for orders after 24 hours Management of Other Prehospital Medications Program (Note: No oral medications until/unless patient passes a bedside swallow screen) Hold all prehospital medications first 24 hours Other program for prehospital medications first 24 hours, i.e., www.icsi.org Institute for Clinical Systems Improvement 5 ) with Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 Give full doses of prehospital medications after 24 hours Ask physician for orders after 24 hours GI Prophylaxis mg every by mouth IV Laboratory/Diagnostics: (those not performed in ED or office) CBC with platelet count STAT Electrolytes, glucose, BUN, creatinine ALT AST GGT Next routine draw (Refer to unit’s protocol.) Next routine draw (Refer to unit’s protocol.) STAT Alk phosphatase CPK (Liver and muscle enzymes are important in preparation for statin medication initiation.) PT/INR STAT Next routine draw (Refer to unit’s protocol.) PTT STAT Next routine draw (Refer to unit’s protocol.) Fasting cholesterol, triglyceride, HDL, LDL Electrocardiogram CT of head without enhancement CT angiogram: Head Neck Magnetic resonance imaging of head (per protocol) Magnetic resonance angiography: Head Neck Carotid doppler ultrasound Indication: Transesophageal echocardiogram With bubble on day (if suspicion of cardioembolic source when patient is stable for study and not vunerable with hypotension and/or sedation) Transthoracic echocardiogram With bubble on day Other Rehabilitation (Therapies will be discontinued by the specific services when unnecessary. Therapies will be advanced to twice daily as appropriate.) Physical therapy Occupational therapy Speech therapy Smoking cessation (for current users) Consults Neurology: reason Hospitalist: reason Neurosurgery: reason www.icsi.org Institute for Clinical Systems Improvement 6 Admission for Ischemic Stroke Order Set for Patients Not Receiving tPA Sixth Edition/July 2012 Cardiology: reason Physical medicine and rehabilitation: reason Chaplaincy for advanced directive OR Other Nutrition: reason Other: Discharge Planning Social service consult for assistance in discharge planning Financial counselor consult Authorized Prescriber Signature: Printed Name: Date/Time of Orders: / / : www.icsi.org Institute for Clinical Systems Improvement 7