UNIVERSITE DE GENEVE TO: PROFESSEUR LOUISETTE ZANINETTI SECTION DE BIOLOGIE DEPARTEMENT DE ZOOLOGIE ET BIOLOGIE ANIMALE 13, RUE DES MARAICHERS, CH-1211 GENEVE 4 Jean HOUMARD Charge de Mission CNRS – Departement des Sciences de la Vie 3, rue Michel-Ange 75794 PARIS Cedex 16 Geneva, September 27th 2004, Concerns: Supporting Letter for Colomban de Vargas’ application to an ATIP-2004 fellowship. To Whom It May Concern: Dear Committee Members, Over the past two years, I have been Vice-President of the University of Geneva in Switzerland, after a long career as full Professor in both the departments of Biology and Geology of the same University. I have no reservation in strongly advocating the nomination of Colomban de Vargas for an ATIP fellowship. I have known Colomban as the supervisor of both his Master and PhD theses. He came to my laboratory with the intention to work on molecular systematics and evolution of any group of protists. As a PhD subject, he was given one of the most difficult groups, the planktonic foraminifera. These protists are not only difficult to collect (living exclusively in the open Ocean) but also extremely challenging for molecular work, because they contain a large number of endosymbiotic and parasitic micro-organisms. On the other hand, the planktic foraminifera have one of the best-known fossil records, offering a unique opportunity to compare mode and tempo of evolution between DNA and fossil data. It was amazing to see how Colomban resolved by himself most technical problems and obtained the first planktonic foraminiferal rDNA sequences. He also showed an extreme enthusiasm and perseverance for establishing collaborations with several marine laboratories around the world (France, UK, US, Israel, Bermuda), and was invited to participate to numerous international scientific cruises, during which he collected a spectacular amount of genomic and environmental data. Colomban’s thesis achievement include the first molecular phylogeny of planktonic foraminifera, multiple analyses of molecular versus morphological evolutionary rates, and mainly the discovery of systematic cryptic diversity within the planktonic foraminifera. This latter result had a fundamental impact on the scientific community, because it demonstrated that tiny -or in some case undetected- morphological differences in the shell may separate fully isolated species of adapted to radically different environmental conditions. This outstanding contribution opens a vast new field of research in Geobiology. It was published in prestigious journals, presented at international symposia and conferences, and Colomban, placed at the very top of his field, was interviewed by several European newspapers and television. In addition to his main project, Colomban was collaborating with many colleagues at the department and actively engaged in several other research projects. He has played a fundamental role in the genetic discovery of the “naked” and fresh-water foraminifera, as well as in the analyses of homeobox genes (with Dr. Brigitte Galliot), or vertebrate polyploidy (with Dr. Hans R. Kobel). Showing an exceptional maturity for a graduate student, Colomban also gave courses in Systematics and entirely supervised the MS thesis of a student, Muriel Bonzon. Since he left Switzerland for a post-doc at Harvard in 2000, I have kept a regular contact with him via e-mails and telephone. It was amazing to see his rapid evolution and integration into the competitive American system. Despite his young age, he was selected as an assistant professor in one of the top-ten institute of marine sciences in the US (IMCS, Rutgers), where he build his own laboratory and successfully directed a small research group over the last two years. Without doubt, Colomban is the most intellectually talented student I ever met in my academic career. His motivation to increase the overall scientific knowledge and to contribute to the successful development of a project is clearly above average. He has achieved international renown by virtue of his extraordinary talent, extensive experience, and unique expertise in molecular biology and marine sciences. His proven scientific creativity goes together with a very warm, caring, and generous personality, which makes of him a scholar of outstanding promise not only for Sciences advancement, but also for the integration of scientific activities in the Society. In conclusion, I strongly advocate the nomination of Colomban de Vargas for an ATIP fellowship. This financial help and encouragement will certainly help him to develop his full talents, which will be an invaluable asset to the international research community. Sincerely Yours, Louisette Zaninetti (PhD) Vice-President Professor, Department of Biology Professor, Department of Geology University of Geneva