Module Specification An online version of this specification is available to prospective students at http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section3_moduledescript/in dex.html GENERAL INFORMATION Module name Advanced Statistical Methods in Epidemiology Module code 2412 Module Organisers Richard Hayes and Tim Clayton Contact email Richard.Hayes@lshtm.ac.uk or Tim.Clayton@lshtm.ac.uk Home Faculty Faculty of Epidemiology & Population Health Level This module is at Level 7 (postgraduate Masters ‘M’ level) of the QAA Framework for Higher Education Qualifications in England, Wales & Northern Ireland (FHEQ) Credit LSHTM award 15 credits on successful completion of this module Accreditation Not currently accredited by any other body Keywords Epidemiology (incl. surveillance), Statistics (incl. risk assessment), Quantitative methods, Communicable diseases (in general), Noncommunicable diseases (in general) AIMS, OBJECTIVES AND AUDIENCE Overall aim To enable students to understand, apply and interpret the results of a range of advanced techniques for the design and analysis of epidemiological studies Intended learning outcomes By the end of this module, students should be able to: Target audience Select, apply and interpret the results of regression methods for the analysis of case-control and cohort studies, using appropriate computer software; Plan a strategy of analysis for an epidemiological dataset, using an appropriate choice of methods; Appreciate the effects of correlated data on epidemiological analysis, and the use of statistical methods which take account of such correlations; Interpret and criticise the statistical methodology presented in published epidemiological papers. This is an advanced module intended for students with a strong grasp of quantitative methods, who have successfully completed the module in Statistical Methods in Epidemiology (2402). 1 CONTENT Session content The module is expected to include sessions addressing the following topics (though please note that these may be subject to change): Regression methods for case-control studies: Unconditional and conditional logistic regression Regression methods for cohort studies and survival analysis: Stratifying on time Poisson regression Cox regression Further issues in the analysis of cohort studies Analysis of correlated data: Random effects models Generalised estimating equations Design and analysis of cluster-randomized trials Miscellaneous topics: Causal diagrams Attributable fractions Additive and multiplicative models Analysis of quantitative data Missing data Strategies of analysis TEACHING, LEARNING AND ASSESSMENT Study resources provided or required Course manual including lecture notes, lecture slides, other relevant material, practicals. Teaching and learning methods New methods will be introduced in lectures followed by practicals. Examples will be taken from studies in both high income and low/middle income countries. The majority of practicals will be computer practicals based on analysis of epidemiological datasets using the package Stata. New databases will be introduced as well as the reanalysis of datasets used in Statistical Methods in Epidemiology to illustrate the additional flexibility provided by regression techniques. Contact time will be divided between lectures, computer practicals, small group discussions and private study. Assessment details Written report (no more than five pages) of a statistical analysis conducted by the student on an epidemiological dataset. The report will include a write up of the strategy used, a presentation of the relevant results and a discussion. For students who are required to re-sit, or granted a deferral or new attempt, the task will be the same as the original assignment but with a different dataset. Assessment dates The hand-in date for the assessment will be Friday 20 May 2016. For students who are required to re-sit, or granted a deferral or new attempt, the next assessment deadline will be the standard School-recommended date in mid/late September 2016. Language of study and assessment English (please see ‘English language requirements’ below regarding the standard required for entry). 2 TIMING AND MODE OF STUDY Duration The module runs for 5 weeks at 2.5 days per week; this module runs between Wednesday lunchtime and Friday afternoon. Dates For 2015-16, the module will start on Wednesday 20 April 2010 and finish on Friday 20 May 2016. Timetable slot The module runs in LSHTM timetable slot E Mode of Study The module is taught face-to-face in London. Both full-time and part-time students follow the same schedule. Learning time The notional learning time for the module totals 150 hours, consisting of: Contact time ≈ 48 hours Directed self-study ≈ 15 hours Self-directed learning ≈ 35 hours Assessment, review and revision ≈ 52 hours APPLICATION, ADMISSION AND FEES Pre-requisites Statistical Methods in Epidemiology (2402) is a pre-requisite for this module. English language requirements A strong command of the English language is necessary to benefit from studying the module. Applicants whose first language is not English or whose prior university studies have not been conducted wholly in English must fulfil LSHTM’s English language requirements, with an acceptable score in an approved test taken in the two years prior to entry. Applicants may be asked to take a test even if the standard conditions have been met. Student numbers Student numbers are typically 100 per year; numbers may be capped due to limitations in facilities or staffing. Student selection Preference will be given to LSHTM MSc students and LSHTM research degree students. Other applicants meeting the entry criteria will usually be offered a place in the order applications are received, until any cap on numbers is reached. Applicants may be placed on a waiting list and given priority the next time the module is run. Full Registration (full participation) by LSHTM research degree students is required for this module. Fees For registered LSHTM MSc students, fees for the module are included within MSc fees (given on individual course prospectus pages). If registering specifically for this module, as a stand-alone short course, individual module fees will apply. Tuition fees must be paid in full before commencing the module, or by any fee deadline set by the Registry. Scholarships Scholarships are not available for individual modules. Some potential sources of funding are detailed on the LSHTM website. 3 Admission deadlines For 2015-16: For registered LSHTM MSc students, the module choice deadline (for Term 2 and 3 modules) is Friday 20 November 2015. If registering specifically for this module, applications may be made at any time but, as places are limited, applications ahead of the MSc deadline are strongly advised. All applications should be submitted at the latest 8 weeks prior to the start of the module. Formal registration will take place on the morning of the first day of the module. ABOUT THIS DOCUMENT This module specification applies for the academic year 2015-16 Last revised 23 June 2014 by Tim Clayton & Richard Hayes London School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT. www.lshtm.ac.uk 4