Learning Aim C Assignment 3 Medical Treatments As a newly appointed medical researcher you have been asked to produce information that describes the drug treatments that are available to the public when our bodies cease to be healthy. You need to provide information about how and when each treatment should be used and the effectiveness of each one. You realise there is a shortage of clear and easy to understand information about treatments available for people suffering from organ failure. They may require different types of treatment like blood transfusions, organ transplants or stem cell therapy to try and restore their health. To address the lack of information, you have decided to research these possible treatments and produce an information pack consisting of leaflets, display materials and/or a PowerPoint® presentation (you could consider including a voice over in your PowerPoint®). An information pack consisting of leaflets, PowerPoint®, display material from your investigations which: • • Describes, analyses and evaluates drug treatments to help restore us to a healthy state Evaluates, describes and explains the principles and uses of blood grouping, transfusions, organ donation and stem cell therapy in restoring us to a healthy state. Investigate the use and misuse of antibiotics using secondary data. Analyse the effectiveness of different kinds of medical treatment in health care using secondary data. Evaluate the use of different kinds of medical treatments, justifying your opinions. Describe the use of anti-fungal, antiviral and analgesic treatments. Explain the importance of blood group matching in blood transfusions. Describe organ donation and approaches used to reduce rejection. 7 2C.P7 7 2C.M5 7 7 7 7 2C.D4 2C.P8 2C.P9 2C.M6 ANTIBIOTICS In 1928 a Scottish scientist called Alexander Fleming discovered that a certain species of fungi produced a chemical that stops bacteria from growing. By the 1940s two other scientists (Florey and Chain) had used this discovery to develop antibiotics to treat injuries in the war. The use of antibiotics has saved millions of lives to date. What was the name of Fleming’s discovery? How did Fleming discover the antibiotic? How do antibiotics work? Are antibiotics used to treat or prevent disease? Name a disease which can be treated with antibiotics How are antibiotics used to treat this disease? Your task is to grow bacteria on agar plates, using safe lab techniques, to investigate which antibiotics are most successful at killing different bacteria. You will record results, draw a graph, and make conclusions about treatment based on your results. First, describe your method, using the diagrams below: Method: Results table: Name of antibiotic used Size of bacteria free zone (mm) Graph: Which antibiotic was better at killing E. Coli, and how can you tell? _______________________________________________________________________________________ _______________________________________________________________________________________ ______________________________________________________________ Analyse the secondary data below and compare it to your results to confirm which antibiotics are most effective at treating different diseases (Influenza virus) Zone of Inhibition Size (mm) Penicillin 0 Meticillin 0 Streptomycin 0 Vancomycin 0 Amoxicillin 0 MRSA Zone of Inhibition Size (mm) Flu (Methicillin Resistant Staphylococcus aureus) Penicillin 0 Meticillin 0 Streptomycin 0 Vancomycin 12 Amoxicillin 0 (Escherichia Coli) Zone of Inhibition Size (mm) Penicillin 0 Meticillin 12 Streptomycin 15 Vancomycin 0 Amoxicillin 0 Staph Wound Infection Which antibiotic is most effective at treating this disease? How can you tell? Which antibiotic is most effective at treating this disease? How can you tell? Which antibiotic is most effective at treating this disease? How can you tell? (Streptococcus) Zone of Inhibition Size (mm) Penicillin 16 Meticillin 0 Streptomycin 10 Vancomycin 10 Amoxicillin 13 Strep Throat Which antibiotic is most effective at treating this disease? How can you tell? Do these results support your results? How? 2C.P7 Investigate the use and misuse of antibiotics using secondary data. TREATMENTS FOR DISEASES Research different types of treatment including antibiotics, analgesics, antifungals and antivirals. You will describe what each is, what diseases it can treat, and the advantages and disadvantages of each type of treatment. Treatment What is it and how does it work? What diseases can it treat? Advantages Disadvantages Antibiotics Analgesics Antifungals Antivirals 2C.P8 Describe the use of anti-fungal, antiviral and analgesic treatments. Antibiotic Resistant Bacteria Explain how a strain of bacteria could become resistant to antibiotics by adding explanations next to each of the diagrams below: What are the dangers of bacteria that are resistant to antibiotics? Why is it important to complete a course of antibiotics and not to stop taking them when you start feeling better? Why is it important that we don’t overuse antibiotics? Explain why some antibiotics are now kept for the most serious diseases. EVALUATING THE EFFECTIVENESS OF TREATMENTS You need to use data to back up your opinions when asked to justify something. You need to find data to answer the following questions: How effective are antibiotics? How effective are analgesics? How effective are antivirals? How effective are antifungals? http://www.bbc.co.uk/guides/z8kccdm Task 3 Find out about the different blood groups. Also add the uses of: blood grouping and blood transfusion and how it can help with different illnesses. _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ ___________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ ___________________________________________________________________________ 2C.P9 Explain the importance of blood group matching in blood transfusions. Task 5 1) Research about organ donation and the types of organs that can be donated ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ ________________________________________________________________________________________ 2) Find out about the methods used by doctors in order to reduce organ rejection __________________________________________________________________________________________ __________________________________________________________________________________________ __________________________________________________________________________________________ __________________________________________________________________________________________ ________________________________________________________________________________________ 3) You will need to use your knowledge of genetics to investigate the role of gene therapy as a treatment for certain conditions and diseases and the effectiveness of this 2C.M6 - Describe organ donation and approaches used to reduce rejection. Finalising Research Commonly used drug treatments available to the public when they are unwell are: anti-fungals antivirals analgesics Your display, leaflets, PowerPoint®, information pack needs to: describe what type of pathogens each of the above should be used to treat, what pathogens they will not be effective against and how they should be used to help improve the health of the body. Another common drug treatment is antibiotics. Access, reference and include some secondary data in your pack/display about antibiotics. Use this data to produce a fact sheet describing how antibiotics should be prescribed, what pathogens they can and cannot treat, how they should be used properly and what can happen if they are over prescribed or if the course is not completed. Extend the use of secondary data to analyse the effectiveness of the drugs in health care. In particular, analyse how antibiotics and the improper use of them is a factor influencing the increase in hospital acquired infections like MRSA (methicillin resistant staphylococcus aureus) or Clostridium difficile. Evaluate the use of the four types of drugs in treating disorders. Justify you opinions regarding their use with evidence from your research. Present the material in an appropriate form in your information pack. Research blood groups, tissue typing, organ donation and rejection and stem cell therapy. Use the information to add sections to your information pack which: identifies the different blood groups and explains their importance in blood transfusions describes why organ donation may be required. Include a description of the principles that are involved in organ donation (blood matching, tissue typing and selecting donors) describes how and why these principles and other methods can be used to help reduce organ rejection evaluates the current potential benefits, and the potential benefits that may be available in the future of stem cell therapy. Criteria 2C.P7 2C.M5 2C.D4 2C.P8 2C.P9 2C.M6 Description Investigate the use and misuse of antibiotics using secondary data. Analyse the effectiveness of different kinds of medical treatment in health care using secondary data. Evaluate the use of different kinds of medical treatments, justifying your opinions. Describe the use of anti-fungal, antiviral and analgesic treatments. Explain the importance of blood group matching in blood transfusions. Describe organ donation and Page ref Completed Checked approaches used to reduce rejection.