International Symposium on Frontiers of Genetics and Genomics The International Symposium on Frontiers of Genetics and Genomics will be held on December 6-8, 2015 in Shenzhen, China. This symposium is jointly organized by the Editorial Office of Journal of Genetics and Genomics, Hereditas (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China, co-organized by the Agricultural Genomics Institute at Shenzhen China Academy of Agricultural Sciences. Journal of Genetics and Genomics (JGG) is a peer-reviewed international journal in the field of genetics and genomics. Research in this field has been progressing rapidly. This symposium aims to highlight the emerging frontiers of genetics and genomics covering humans, animals, plants and microbes. Over 30 leading scientists from different countries will share their cutting-edge discoveries in this symposium. We sincerely hope this symposium will provide an international platform for scientists to exchange new ideas, discuss new advances and facilitate collaborations. Chair: Yongbiao Xue Executive Chair: Qian Qian Location: Shenzhen, China Schedule: Dec. 6th Arrival and Reception th Dec. 7 Symposium th Dec. 8 (morning) Symposium th Dec. 8 (afternoon) Departure Registration deadline: Before November 20th, 2015 or 150 participants registered. Registration fee: Professionals (including Post Docs) 1500 CNY Students 800 CNY Venue: AIRLAND HOTEL (雅兰酒店) No. 92 Yanmei Road, Yantian District, Shenzhen, China (深圳市盐田区大梅沙盐梅路 92 号) If you would like to attend the symposium, please fill in the below table and send the email to fgg@genetics.ac.cn. Name Gender Affiliation Professional title/Student Accommodation (single or shared) E-mail Speaker List Session I Medical Genetics and Genomics Stephen Kearsey (University of Oxford, UK) Characterization of replicative DNA polymerases associated with cancer predisposition in fission yeast Jin-Qiu Zhou (Institute of Biochemistry and Cell Biology, CAS, China) Inhibition of telomere recombination promote cell longevity Zuoheng Anita Wang (Yale University, USA) Genome-wide and epigenome-wide association study in an HIV cohort Kin Fai Au (University of Iowa, USA) Transcriptome analysis by Hybrid-Seq Wensheng Wei (Peking University, China) CRISPR screening in the study of human disease Yun-Fai Chris Lau (University of California, USA) The human Y chromosome as a genetic burden for man Jingwu Xie (Indiana University, USA) To decipher the signaling events driving liver metastasis of pancreatic cancer Yidong Bai (Columbia University, USA) The implications of mitochondrial haplogroups and mutations in cancers Huidong Shi (Georgia Regents University, USA) Modulation of indoleamine 2, 3-dioxygenase 1 expression by activated human T-cells is controlled by epigenetic mechanisms in breast cancer cells Xin-Hua Feng (Baylor College of Medicine, USA) How tumor suppressors cooperate in control Wei Zhou (Emory University School of Medicine, USA) Targeting pre-ribosomal RNA synthesis in NSCLC Zhongsheng Sun (Beijing Institutes of Life Science, CAS, China) Genetic landscape of Chinese autism patients Yong-Gang Yao (Kunming Institute of Zoology, CAS, China) An evolutionary elucidation of the genetic basis of neuro-psychiatric disorders Ruifu Yang (Beijing Institute of Microbiology and Epidemiology, China) Evolution of Yersinia pestis virulence Session II Animal Genetics and Development Cahir O’Kane (University of Cambridge, UK) Roles of spastic paraplegia genes in organization of axonal endoplasmic reticulum Ji-Long Liu (University of Oxford, UK) The cytoophidium and its kinds: compartmentation and filamentation of metabolic enzymes Wu-Min Deng (Florida State University, USA) Tumor hotspots in Drosophila Yu Cai (Temasek Life Sciences Laboratory, Singapore) Defining the germline stem cell niche activity in the Drosophila ovary Yongqing Zhang (Institute of Genetics and Developmental Biology, CAS, China) Lipids in the brain--mutations in Acyl-CoA synthetase results in minibrain due to reduced neuroblast activity Jinsong Li (Shanghai Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, CAS, China) CRISPR-Cas9-meidated genetic screening in mice with haploid embryonic stem cells Yikang Rong (Sun Yat-sen University, China) Packing and repacking of the paternal genome: lessons learned from studying haploid embryos produced in a diploid organism Liangbiao Chen (Shanghai Ocean University, China) Evolution of cold-responsive genetic network in Teleost fishes Session III Plant Genetics and Genomics Dacheng Tian (Nanjing University, China) Mutational "Matthew Effect" during meiosis in plants Zhukuan Cheng (Institute of Genetics and Developmental Biology, CAS, China) Homologous recombination in rice Hong Qiao (University of Texas at Austin, USA) Histone modification in ethylene response Mingliang Xu (China Agricultural University, China) An atypical thioredoxin imparts early resistance to sugarcane mosaic virus in maize Zhiyong Wang (Carnegie Institution for Science, USA) The genomic map of steroid actions Sanwen Huang (Institute of Vegetables and Flowers, CAAS, China) Big data and vegetable biology Yongbiao Xue (Institute of Genetics and Developmental Biology, CAS, China) Evolution of interspecific reproductive barriers in Solanum