Pharmacology II NURS 2021 North Arkansas College Harrison, AR 1 North Arkansas College Department of Nursing Harrison, AR Course Title: NURS 2021-Pharmacology II (Fall) Course Instructor: Cheryl Kinder, MSN, RN Office: M179 Contact Information: Phone: 870-391-3561 (office) E-mail: ckinder@northark.edu Office Hours: Monday Tuesday Wednesday Thursday Friday 9:00 am -2:00pm (on-line) Clinical Sites (Baxter Regional Med Center) 8:00 am – 3:00 pm 2:30 pm – 4:00 pm By Appointment Course Description: NURS 2021 Pharmacology II (1) 1L Pharmacology II is a 16 week course that is a continuation of NURS 1011, Pharmacology I. Emphasis is placed on generic names, therapeutic actions, indications/uses, side effects, adverse reactions, and nursing implications of medication administration. Safety, clinical reasoning, and patient teaching concepts are stressed to reduce preventable errors and promote positive patient outcomes. Co-requisite: NURS 2104 Credit and Time Allotment: One Semester Credit Hour One hour lecture weekly Prep time prior to class Course Location: A104 Course Meeting Time: Thursdays 1:30 – 2:20 Prerequisites/Co-requisites: NURS 1114-Medical Surgical Nursing I NURS 1011-Pharmacology I NURS 2014-Medical Surgical Nursing II Course Requirements: Students are expected to take exams as scheduled. Make up exams will be given only if advance notice of absence is approved and make-up exam is taken within 1 week of the original test date. Students are allowed only one make-up exam per course. Grades ≥ 79% must be maintained for program progression as outlined in Registered Nursing Program Handbook. Nursing students will be expected to progress through the basic collection and comprehension of pharmacologic information into the analysis of application of use and response of varied cohort populations. If exam averages are 2 <79% following the 2nd exam the student will be expected to see the instructor. Preparation for class is mandatory. Pop quizzes and individual/group participation in content presentation is to be expected. Withdrawal from the course is the responsibility of the student. The North Arkansas College catalog informs students of deadlines and that you are responsible for officially withdrawing from the course you are no longer attending. Failure to do so will result in an F on your transcript. I will not withdraw you from the course. Grading/Attendance: Grading, attendance and examination policies for this course and all nursing courses are found in the North Arkansas Registered Nursing Program Handbook Grading Scale: 90.5-100 A 83.5-90.4 B 78.5-83.4 C 69-78.4 D < 69 F Comprehensive Final Exam = 20% 5 Unit exams =70% Homework-Quizzes = 10% Required Texts: Kee, J., Hayes, E., & McCuistion, L. (2015). Pharmacology: A nursing process approach, (8thed). St. Louis: Saunders. ISBN:978-1-4557-5148-8 ATI text: RN Pharmacology for Nursing (6thed) MAXI-LEARN learning system notebook (2013) Suggested Text: Current Drug Book Ignatavicius, M. and Workman, L. (2013) Medical-Surgical Nursing: Patient-Centered Collaborative Care, (7 th ed.), St. Louis, MO: Elsevier-Saunders Teaching-Learning Activities Discussion Videos Lecture Simulation (integrated into Medical Surgical Nursing II) Clinical Practicum Application Case Studies ADA Statement: North Arkansas College complies with Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act of 1990. Students with disabilities who need special accommodations should make their requests in the following way: (1) talk to the instructor after class or during office hours about their disability or special need related to classroom work; and/or (2) contact Special Services in Room M154 (learning Commons) and ask to speak to Kim Brecklein. Student Responsibilities and Statement of Action for cases of suspected and verified Academic Dishonesty as well as what constitutes academic dishonesty is addressed in the Registered Nursing Program Handbook. 3 Upon successful completion of this course students will be able to: Course Outcomes #1 Discuss drug administration, documentation and teaching as components of safe effective nursing care, utilizing the nursing process. (Measured by exam and simulation/clinical application) #2 Describe the roles and responsibilities of the registered nurse regarding drug administration. (Measured by exam, clinical practice application and discussion) #3 Explain and demonstrate the 6 rights of medication administration in both classroom assessment and clinical practice (Measured by exam and clinical/lab application) #4 Apply critical reasoning/thinking in simulated situations concerning administration of medications to various populations (Measured by exam, case studies and discussion) #5 Plan nursing interventions necessary to the administration of medications and the teaching strategies necessary to gain client compliance. (Measured by exam, case study) #6 Explain the pharmacologic classification of drugs, their mechanism of action, common side effects; potential for adverse reactions, contraindications and other nursing considerations and interventions. (Measured by exam and classroom discussion) #7 Recognize cultural considerations relating to compliance and administration of medications. (Measured by exam and classroom discussion, case study) Correlating Program Outcomes Professional Identity Nursing Judgment GLO 3 Professional Identity Nursing Judgment GLO 4 Professional Identity Nursing Judgment GLO 2 Human Flourishing Nursing Judgment Spirit of Inquiry GLO 1 Professional Identity Human Flourishing GLO 2 Professional Identity Nursing Judgment GLO 3 Professional Identity Human Flourishing Nursing Judgment Spirit of Inquiry GLO 5 Northark General Learning Outcomes (GLO) The learning outcomes of general education will be common to all students regardless of major. When students have completed the general education component of their studies, they should be able to: 1. Apply critical thinking and problem solving skills across disciplines. 2. Apply life skills in areas such as teamwork, interpersonal relationships, ethics, and study habits. 3. Communicate clearly in written or oral formats. 4. Use technology appropriate for learning. 5. Discuss issues of a diverse global society. 4 August 2015 Sunday Monday Tuesday Wednesday Thursday Friday Saturday 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Classes Begin 18 19 20 Orientation 21 22 28 29 Vaccines 23 24 25 26 27 Skin Eye-Ear disorders Maxi-Learn Cards due 30 31 5 September 2015 Sunday 6 Monday 7 Tuesday Wednesday Thursday Friday Saturday 1 2 3 HIV & AIDS Exam 1 (online) 9/3 (5 pm)-9/5 (5pm) 4 5 8 9 10 Endocrine 11 12 17 Antidiabetics 18 19 24 Urinary Disorders 25 26 Maxi-Learn Cards due 13 14 15 16 Homework Guided reading dueupload 20 21 22 23 27 28 29 30 6 October 2015 Sunday 4 Monday 5 Tuesday 6 Wednesday 7 Thursday Friday Saturday 1 Exam 2 (class) 2 3 8 Nutritional Support 9 10 15 GI Disorders 16 17 22 23 24 30 31 Maxi-Learn Cards Due 11 12 13 14 Homework GI Case Study due upload 18 25 19 26 20 27 21 28 Antiulcer Exam 3-online 10/22 (5pm)10/24 (5pm) 29 Anticancer Maxi-Learn Cards Due *material online (no class) 7 November 2015 Sunday 1 Monday 2 Tuesday 3 Wednesday 4 Thursday 5 Friday Saturday 6 7 13 14 20 21 27 28 Targeted Therapies Bio-Modifiers 8 9 10 11 12 Men & Women Repo* 15 16 17 18 19 Infertility, STDs Maxi-Learn Cards Due Unit Overview 22 23 24 25 26 Thanksgiving Break no classes 29 30 *material online (no class) 8 December 2015 Sunday Monday Tuesday 1 6 7 8 Wednesday 2 9 Thursday Friday Saturday 3 4 Exam4 (Class) Final blueprint Available on Portal 5 10 11 12 Final Exam (class) 13 14 mhapp 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Classes begin 1/11/16 MS III Pharm III 9 Calendar Overview-Exams Calendar is subject to changes-watch Portal for announcements Unit 1-Exam 1: Sept. 3-5 (online) Vaccines-Chapter 36 Drugs for Eye & Ear Disorders-Chapter 49 (Demonstrations) Drugs for Skin Disorders-Chapter 50 HIV and AIDs Related Drugs-Chapter 35 Unit 2-Exam 2: Oct. 1 (class) Endocrine-Chapter 51 Antidiabetics-Chapter 52 (homework) Urinary disorders-Chapter 34 Unit 3-Exam 3: October 22-24 (online) Nutritional Support-Chapter 17 GI Disorders-Chapter 47 (homework) Antiulcer Drugs-Chapter 48 Unit 4-Exam 4: Dec. 3 (class) Anticancer Drugs-Chapter 37 10 Targeted Therapies to Treat Cancer-Chapter 38 Biologic Response Modifiers-Chapter 39 Men and Women’s Reproductive Health-Chapters 56-57 Infertility and STDs-Chapter 58 Antivirals , etc-Chapter 33 *HOMEWORK NOT ACCEPTED AFTER 5PM ON DUE DATE Maxi-Learn Cards considered Homework and are due at beginning of class specified on calendar (no late cards accepted) Final Blueprint-Dec. 3 11 Unit I: Vaccines, Eyes, Ears, Skin, HIV/AIDs Objectives 1. Discuss the 6 QSEN Competencies and relationship to medication errors. (review) 2. Compare and contrast the different types of immunity. 3. Develop a teaching plan for parents concerned about use of vaccines. 4. Demonstrate proper technique for administration of eye and ear medications. (pgs. 135-136) and teaching needs. 5. Discuss the action, side effects, contraindications of drugs used for glaucoma 6. Discuss the action, routes, side effects, reactions of the common drugs used for treatment of eye and ear problems. 7. Discuss glaucoma, types, classifications, herbal interactions. 8. Give examples of drug/contact induced dermatitis and treatments. 9. Discuss the treatment options and teaching needed by patients receiving medications for acne. 10. Examine nursing interventions specific to the patient receiving treatment for burns with topical antiinfectives. Course Outcomes: 1, 2, 3 Content I. Vaccines A. Types of “immunities” B. Types and uses of each vaccines 1. conjugate 2. recombinant subunit vaccines 3. adjuvant C. Disease prevention D. Adult Immunizations 1. cocooning (Tdap) F. Specific Vaccines 1. Varicella a. nursing process applied b. VIS (Vaccine Information Statement) II. Eye and Ear Disorders A. Forms and use 1.Stains 2. topical anesthetics, 3.anitinfectives, 4.anti-inflammatories, 5. decongestants, lubricants B. Antiglaucoma agents 1. Prostaglandin Analogues (Latanoprost) 2. Cholinergic Agents 3. Beta Blockers 4. Nursing Considerations III. Dermatological Problems A. Acne B. Psoriasis C. Warts D. Dermatitis E. Impetigo F. Hair Loss G. Burns Assignments Reading: Kee, J., Hayes, E., & McCuistion, L. 36: Vaccines (also applicable to Pediatric studies) 49: Drugs for Eye and Ear Disorders 50: Drugs for Dermatological Disorders (also in Pediatric Nursing) 12: Safety and Quality in Pharmacotherapy (review) 13: Medication Administration (review) ATI: Chapters 14, 41 MAXI-LEARN Zostavax Latanopost Pilocarpine HCL Retin-A Tetracycline Handouts Demonstration expectations Websites: www.qsen.org www.cdc.gov/medicationsafety www.immunize.org (VIS in different languages) Videos Exam 1: 9/3 (online) will open following class 9/3-9/5 (times announced 12 Unit II-Endocrine, Antidiabetics, Urinary Disorders Objectives 1. Differentiate between the action and use of antiinfectives, antispasmodics, antimuscarinics, analgesics, stimulants as they pertain to treatment of Urinary Tract Infections (UTIs) 2. Illustrate and apply the nursing process to treatment of Endocrine disorders. 3. Compare pathophysiology Type 1 and Type II and treatment of each. 4. Compare the onset, peak and duration of each type of insulin. 5. Examine and discuss the action and teaching of use of oral antidiabetics. 6. Communicate knowledge of teaching for the insulin dependent patient. 7. List signs and symptoms of Hypoglycemic insulin reaction. 8. List signs and symptoms of hyperglycemic reactions (diabetic acidosis) Content I. Urinary tract infections-defined A. Antiinfectives-Macrodantin/nitrofurantion B. Antispasmodics-oxybutynin/Ditropan C. Analgesics-pyridium/phenazopyridium D. Antimuscarinics/Anticholinergics Detrol/tolterodine E. Urinary Stimulants- bethanechol chloride (Urecholine) II. Endocrine system-defined A. Pituitary-Athcar Gel 1. Nursing Implications B. Thyroid-Levothyroxin 1. Hypothyroidism-Synthroid /T4 2. Hyperthyroidism-PTU, Tapazole 3. Drug interactions and Nursing C. Parathyroidism 1. hypoparathyroidism-Calcitriol/Rocarol 2. Hyperparathryoidism calcitonin salmon/Fortical D. Adrenal 1. glucocorticoid-Cortisone 2. Mineral corticoids III. Antidiabetics A. oral agents B. insulins C. Glucagon D. Nursing interventions E. Safety 1. herbal interactions (pg 765) IV. hypoglycemic reaction-define V. ketoacidosis-define Course Outcomes: 2,4,6,8 Assignments Reading: Kee, J., Hayes, E., & McCuistion, L. 34: Urinary Tract Disorders 51: Endocrine Drugs 52: Antidiabetics ATI: Chapters 39, 40, 46 MAXI-LEARN Macrodantin Pyridium Ditropan Metformin Synthroid Tapazole Deltasone Insulins (see pg. 762-do each type) Glucophage Handouts Review Key Terms Homework: Guided Reading Neuropathy Quiz and Answers (not required) Videos Exam 2: 10/1 (in class) 13 Unit III-Nutritional Support, GI, Antiulcer 1. Explain the differences between enteral and parenteral nutrition. 2. Describe the routes available for enteral feedings. 3. Describe the nursing interventions for patients receiving enteral nutrition. 4. Indicate the complications that might occur with the use of parenteral/enteral nutrition and nursing management of these complications. 5. Compare the pharmacologic treatment of vomiting, diarrhea, and constipation. 6. Employ the nursing process for the patient taking antiemetics, antidiarrheals, and laxatives. 7. Describe the differences (between) and uses for osmotic, stimulants, and bulk forming laxatives. 8. List and compare the actions of the 7 groups of antiulcer drugs. 9. Differentiate between peptic, gastric, duodenal ulcers and GERD and the prescribed treatment. I. Nutritional Support A. define enteral/parenteral nutrition 1. examples B. Complications C. Nursing Interventions II. Gastrointestinal Tract Disorders A. Vomiting 1. non-pharmacological management 2. OTC med 3. Rx meds-classes a. antihistamines/anticholinergics b. dopamine antagonists c. butyrophenines d. benzodiazepines e. serotonin antagonists f. glucocorticoids g. cannaboids h. miscellaneous B. Diarrhea 1. antidiarrheals 2. non-pharmacological management C. Constipation 1. laxatives a. stimulants-examples b. osmotic-examples c. bulk forming-examples III. Antiulcer Drugs A. Define ulcers 1. pathophysiology 2. h-pylori B. Drug treatment 1.. Tranquilizers 2. Anticholinergics 3. Antacids 4. Histamine2 blockers 5. PPIs 6. Pepsin inhibitors 7. Prostaglandin inhibitors A. Nursing Interventions Reading: Kee, J., Hayes, E., & McCuistion, L. 17: Nutritional Support 47: Drugs for GI Disorders 48: Antiulcer Drugs ATI: Chapters 28, 29 MAXI-LEARN Antiemetics (include Marinol) Antidiarrheals Laxatives (example of each group) Handouts/Course Materials See Portal Homework-GI Case Study Class Flash quiz Videos Exam 3: will open following class 10/22 (5 pm)-10/24 (5pm) 14 Unit IV: Men & Women’s Health, Infertility, STDs, Antituberculars, Antivirals, Anticancers Objectives 1. Describe methods of contraception and associated patient and family teaching. 2. Provide information and interventions that are applicable (non-pharmacologic/pharmacologic) to women who are menopausal or in perimenopause. 3. Differentiate between the types of medications used to treat or manage osteoporosis. 4. Differentiate common conditions for which androgen/antiandrogen therapy are indicated. 5. Explain risks of androgen therapy and assessment of the patient on androgen therapy. 6. List the pharmacologic therapies and the expected outcomes of these therapies used in treatment of women’s health issues. 7. Determine and list teaching needs for patient receiving an antihelmintic. 8. Discuss safety issues for nurses administering chemotherapeutic agents. 9. Compare the mechanisms of action of targeted therapies for cancer with those of standard chemo drugs. 10. Incorporate the nursing process related to the needs of the patients receiving BRMs into teaching plan. 11. Discuss commonalities between all cancer treatment modalities. Content I. Women’s Repro Health and Menopause A. Contraception methods-Routes B. Withdrawal bleeding C. Nursing Interventions-contraception 1. Nursing Process pgs. 856-58, D. Menopause F. Medical Abortion G. Osteoporosis II. Men’s Health and Reproductive Health A. Androgens (natural) 1. Testosterone a. uses b. nursing implications B. Antiandrogens 1. Oxandrolone/Oxandrin a. uses b. nursing implications C. Delayed Puberty, Pituitary, Thyroid, Adrenal Disorders and Treatment E. Sexual Dysfunction F. BPH-Benign Prostate Hyperplasia III. Infertility, STIs, Health Disorders (female) A. Common conditions and treatment 1. abnormal bleeding patterns 2. fertility issues 3. premenstrual syndrome 4. STIs IV. Antivirals, Antimalarials, Antihelmics A. Virus treatment for infections (flu) B. Vaccines-intro (more in chapter 36) C. Antivirals (non-HIV) 1. acyclovir (see prototype pg 452) D. Helminths 1. Side effects of treatment options Assignments Reading: Kee, J., Hayes, E., & McCuistion, L. 56: Drugs for Women’s Reproductive Health and Menopause 57: Drugs for Men’s Health and Reproductive Disorders 58: Drugs for Disorders in Women’s Health, Infertility, and Sexually Transmitted Infections 33: Antivirals, Antimalarials, and Antihelmintics 37: Anticancer Drugs 38: Targeted Therapies 39: Biologic Response Modifiers ATI: Chapters 31, 47, 48 MAXI-LEARN Premarin Silendifil Flomax INH Diflucan Retrovir-AZT Oncovin Cytoxin Megace Avastatin Neupogen Powerpoint Handouts: Cancer Summary for study Men and Women’s Health 15 V. Anticancer Drugs A. Cytoxan/cyclophosphamide 1. Nursing Process B. Fluorouracil, 5-Fu 1. Nursing Process C. Doxirubicin/Adriamycin 1. Nursing Process D. Vincristine/Oncovin, plant alkaloid 1. Nursing Process VI. Targeted Therapies A. Defined B. Imatinib/Gleevec C. Erlotinib/Tarceva D. Rituximab/Rituxin VII. Biological Response Modifiers A. Defined-purpose B. Drugs 1. Epogen 2. Neupogen 3. Leukine C. Nursing Process Review the key terms in each chapter (particularly 37, 38, 39) http://www.cdc.gov/STD/treatment Videos Exam 4: Dec. 3 (class) 16 Supplemental Material: Pictorial Guide to Herbals 17 Common Herbal Therapies: COMMON HERB Source Aloe Vera Indications/ Uses Constipation Pain/healing of burns, wounds, sunburn, psoriasis Action 2 substance: Gel & Latex Black Cohosh Chamomile Dong Quai Side effects Pregnancy/Lactation Children Ulcerative Colitis Cardiac glycosides, antiarrhythmics, thiazide diuretics, licorice, corticosteroids, antidiabetics Long-term use: Arrhythmias Neuropathies Edemas Albuminuria Hematuria Powerful cardiac stimulant Sedative effects on nervous system Cap/Tab Tincture Pregnancy/Lactation Children Antihypertensives Affect iron absorption digoxin Dizziness Headache Nausea Changes in heart rate Antispasmodic & antiinflammatory Sedative effects Tea None known circulation as well as kills bacteria Latex: stimulant laxative Digestive and GI complaints Irritable Bowel Syndrome Infant Colic Anxiety PMS Menopausal symptoms From same family as carrots, parsley and poison hemlock Phytoestrogen activity; vasodilation, small muscle relation Contains B12 Interactions PO Topical Topical gel: some PMS Menstrual Cramps Menopausal symptoms Palpitations Irritability Forms Tea Tincture Allergy to ragweed sedative affects Interfere with anticoagulants simvastatin Not a lot known about this drug. Recommendation is to avoid. coumadin Rash Photosensitivity Fever Excessive menstrual bleeding 18 Echinacea Immune enhancer Respiratory Infections & UTIs Root: flu like symptoms Snakebites Furthering phagocytosis by means of increasing leukocytes and spleen cells and activating granulocytes Oral Topical Immunocompromised people to avoid GI upset / diarrhea Lozenges/tincture: numbness or tingling Evening primrose PMS Prostaglandin disorder Diabetic neuropathies Chronic inflammatory conditions (eczema) Estrogen promoter PO (oil) Pregnancy/lactation seizure threshold of anticonvulsants Anticoagulants / Antiplatelet drugs Slow blood clotting Feverfew Migraine Arthritis Inhibit platelet aggregation and act as a serotonin antagonist in mediating vascular headaches PO Topical May affect blood clotting Garlic Hypercholesterolemia Mild HTN Colds & Flus Caps Cloves Pregnancy/Lactation (may stimulate labor & cause infant colic) Hypothyroidism Anticoagulants Post-feverfew syndrome: fatigue, headache, joint pain, nervousness Chewing leaves may cause sores in mouth Heartburn Flatulence Gastric irritation Decreased RBCs Dizziness Diaphoresis Cap/Tab Tincture Pregnancy Thrombocytopenia Anticoagulants Hx of gallstones Gastric discomfort Anorexia Cap/Tab Tincture Pregnancy/lactation Children Anticoagulants Thiazide diuretics ( BP) Headache Gastric distress Toxicity: vomiting, diarrhea, dermatitis, irritability (purple coneflower) Ginger Nausea Morning sickness Motion sickness Gastric protection with NSAIDS Ginkgo Allergic rhinitis Alzheimer’s disease / dementia Anxiety/stress Raynaud’s disease Tinnitus, vertigo, altitude sickness Detoxifies body and immune function platelet aggregation HDL and cholesterol Antimicrobial activity Hypoglycemia Stimulates digestion bile and motility Antispasmodic platelet aggregation absorption and excretion of cholesterol Antioxidant Peripheral vasodilation platelet aggregation 19 Ginseng Cold & flu prevention Adaptation to stress Chronic fatigue syndrome Supports adrenal glands, enhances energy levels by inhibiting alarm phase SNS response, stimulates RBC production, decreases blood sugar levels Cap/Tab Tea Tincture Pregnancy/Lactation BP > 170/90 Children Bipolar/psychotic D/O DM Anticoagulants effects of caffeine Falsely elevate digoxin levels Pregnancy/Lactation HTN effects of heparin, anticoagulants, cardiac glycosides effects of many cardiac meds Pregnancy/Lactation Children Parkinsonism/Levodopa CNS sedating effects HTN Palpitations Diarrhea Insomnia Goldenseal Infection (resp, GI, UTI) Cholecystitis Cirrhosis Stimulates immune system and bile secretion Cap/Tab Kava Anxiety Insomnia Skeletal muscle spasm Psychotic D/O CNS sedation without loss of mental acuity or memory Cap/Tab Tea Licorice Viral infection Upper Resp. Infection Inflammation Addison’s disease Depression Ulcers Anti-inflammatory Antibacterial Antiviral Antidepressant Laxative Cap/Tab Team Tincture DGL Pregnancy/lactation Children HTN Kidney/Liver Dz Caution with DM Consuming 2ounces of black Licorice daily for 14 days may cause arrhythmias in people over 40 years of age. Ma Huang (ephedra) Weight loss Appetite suppression Stimulant Cap Tea Tinctures Heart disease or problems HTN Asthma / Lung disease Insomnia Glaucoma Kidney disease Bipolar/Depression SERIOUS/FATAL SIDE EFFECTS Heart Attack Stroke Irregular heartbeats Sudden death Stimulate side effects Headache Hepatotoxic (high doses) Toxicity: CNS depression, restlessness, seizures, Cardio collapse GTN Headache Weakness Liver toxicity 20 Milk thistle Liver disease Cholecystitis Psoriasis regeneration of liver cells antioxidant activity Cap/tab Tincture Pregnancy/Lactation Children Diarrhea n/v Menstrual changes Peppermint IBS Indigestion Cholecystitis Infant colic Nasal decongestant Musculoskeletal pain (topical) Itching (Topical) Mood swings Mild to Mod Depression Anxiety Sleep disorders Burns/Wounds (topically) neuralgia BPH Chronic cystitis Sexual potency Antispasmodic bile flow External analgesic Cap/Tab Tea Tincture/ Oil No known drug interactions May interfere with iron absorption None known Proposed: *Inhibition of serotonin, dopamine, norepinephrine *Binds to GABA-A, GABA-B receptors blocking the binding of GABA Tea Tincture Pill Skin photosensitivity Headache GI upset Dry mouth Dizziness Confusion Cap/Tab Tea Extract Pregnancy/Lactation Antidepressants MAOIs Children <2 May effect of digoxin Iron (inhibits absorption of iron) Avoid in pregnancy, lactation , children, clients with breast CA May interfere with PSA test or antiinflammatories effects St. John’s Wort Saw Palmetto size of prostate breakdown of estrogen, progesterone, & prolactin Antiandrogenic Diuretic Headache Dysuria Back pain 21 Valerian Insomnia Stress headaches Anxiety Muscle/Menstrual cramps Sedative/hypnotic Antispasmodic deep sleep Cap/Tab Tea Tincture Alcohol Sedatives Avoid in pregnancy Monitor LFT (long term) Anxiety Headaches GI upset Hangover effect (high doses) Much of the information for this pictorial reference is taken from Chapter 6 in Kee, Hayes, McCuiston, 8e. Pharmacology. Many of these “herbs” are harvested in our area. Studies continue and there are many side effects not listed in this chart. Consider that there are different grades and qualities of these preparations and some of the Chinese herbal products have been found to be contaminated with heavy metals or even some prescription drugs. When taking health histories it is important to herbal remedies and maybe to refer to them as homeopathic remedies (include use of teas, tinctures, tablets and dried herbs). St. John’s Wort has many known drug interactions, most decreasing the intended effects of the Rx drugs. Not listed here is sassafras. Tea made from the roots in early spring was said to “purify the blood of winter stagnation”. Traditionally the roots are only used for a few weeks in the early spring. The safrole oil contained in the bark of the root has been banned from use in Root Beer and candy as it was determined to be carcinogenic when tested on rats. Sassafras leaves are ground and used to thicken gumbo when okra is not in season (Creole spice filé). 22 SYLLABUS ACKNOWLEDGEMENT Course: ___NURS 2021-Pharmacology II Semester: ___Fall _________________ ______________________________________ I acknowledge by signing below that I have received the syllabus for the course indicated above. I have reviewed the syllabus and understand the objectives of this course. Further, I understand how my performance will be evaluated and how my final grade will be determined. I am aware of my instructor’s office hours, and I know how to contact him or her for help with and/or clarification of course contents or procedures. ________________________________________ (Student Signature) _________________________________________ (Date) 23