BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE Gajewski, Byron J. Associate Professor of Biostatistics & Nursing eRA COMMONS USER NAME bgajewski DEGREE (if applicable) YEAR(s) Marquette University, Milwaukee, WI BS 1993 Civil Engineering, Mathematics Marquette University, Milwaukee, WI MS 1995 Mathematics Texas A&M University, College Station, TX PhD 2000 Statistics INSTITUTION AND LOCATION FIELD OF STUDY A. Position and Honors Positions and Employment 2000−2002 Statistical Consultant to University of Florida School of Medicine 2000−2002 Assistant Professor of Statistics, St. Cloud State University 2002−2008 Assistant Professor, University of Kansas Schools Nursing and Allied Health 2008-pres Associate Professor of Biostatistics, University of Kansas School of Medicine 2008-pres Associate Professor of Nursing, University of Kansas School of Nursing Honors 1997 2008 2009-Pres Kosciusko Foundation Fellowship Gajewski & Mayo (2006) study quoted in NHLBI’s RFA-HL-08-013 NIH Peer Review Committee, Clinical Hematology Special Emphasis Panel, reviewer Other Experience and Professional Memberships 1996-Pres American Statistical Association 2004-2008 Council, American Statistical Association, Kansas – Western Missouri Chapter 2002-Pres Eastern North American Region, International Biometrics Society 2006-Pres Reviewer Nursing Research 2006-Pres Reviewer Research in Nursing & Health 2006-Pres Reviewer Statistics in Medicine B. Selected Peer-reviewed Publications (Selected from 83 peer-reviewed publications). Bott and Boyle are underlined in publications below to indicate co-Is in this study. Five most relevant to the current application (in chronological order) 1. Gajewski, B.J., Hart, S., Bergquist, S., Dunton, N. (2007). Inter-rater reliability of pressure ulcer staging: Probit Bayesian hierarchical model that allows for uncertain rater response. Statistics in Medicine, 26(25), 4602-4618. (PMID: 17393413) 2. Gajewski, B., Lee. R., Bott, M.J. Paimjariyakul, U., Taunton. R.L. (2009). Distribution of data envelopment analysis efficiency scores: An application to nursing homes’ care planning process. Journal of Applied Statistics, 36 (9), 933-944. 3. Gajewski, B.J. (2010). Comments on ‘A note on the power prior’ by Neuenschwander, Branson, Spiegelhalter. Statistics in Medicine, 29(6), 708-709. 4. Gajewski, B.J., Boyle, D.K., Thompson, S., (2010). How a Bayesian might estimate the distribution of Cronbach’s alpha from ordinal-dynamic scaled data: a case study measuring nursing home residents quality of life. Methodology: European J of Research Methods for the Behavioral and Social, 2, 71-82. 5. Gajewski, B.J., Boyle, D.K., Miller, P., Oberhelman, F., Dunton, N. (2010). A multilevel confirmatory factor analysis of the practice environment scale (PES): a case study. Nursing Research, 59(2), 147153. Ten additional recent publications of importance to the field (in chronological order) 1. Gajewski, B.J., Sedwick, J.D., Antonelli, P.J. (2004). A log-normal distribution model of the effect of bacteria and ear fenestration on hearing loss: a Bayesian approach. Statistics in Medicine, 23(3), 493-508. (PMID: 14748041) 2. Gajewski, B.J., Thompson, S., Dunton, N., Becker, A., Wrona, M. (2006). Inter-rater reliability of nursing home surveys: a Bayesian latent class approach. Statistics in Medicine, 25(2), 325-344. (PMID: 15977287) 3. Gajewski, B.J., Mayo, M.S. (2006). Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors. Statistics in Medicine, 25(15), 2554-2566. (PMID: 16345057) 4. Gajewski, B.J., Lee, R., Thompson, S., Dunton, N., Becker, A., Wells, V. (2006). Non-normal path analysis in the presence of measurement error and missing data: a Bayesian analysis of nursing homes’ structure and outcomes. Statistics in Medicine, 25(21), 3632-3647. (PMID: 16374902) 5. Gajewski, B.J., Petroski, G., Thompson, S., Dunton, N., Wrona, M., Becker, A., Coffland, V. (2006). Letter to the editor: the effect of provider-level ascertainment bias on profiling nursing homes by Roy J, Mor V. Statistics in Medicine, 25(11), 1976-1977. (PMID: 16680802) 6. Gajewski, B.J., Hall, M., Dunton, N. (2007). Summarizing benchmarks in the National Database of Nursing Quality Indicators using bootstrap confidence intervals. Research in Nursing & Health, 30, 112-119. (PMID: 17243112) 7. Gajewski B. & Simon S. (2008). A one-hour training seminar on Bayesian statistics for nursing graduate students. The American Statistician, 62(3), 190-194. 8. Gajewski, B.J., Simon, S., Carlson, S. (2008). Predicting accrual in clinical trials with Bayesian posterior predictive distributions. Statistics in Medicine, 27(13), 2328-2340. (PMID: 17979152) 9. Gajewski, B.J., Mahnken, J.D., Dunton, N., (2008). Improving quality indicator report cards through Bayesian modeling. BMC Medical Research Methodology 8:77. (PMID: 19017399) 10. Gajewski, B.J., Nicholson, N. and Widen, J.E. (2009). Predicting hearing threshold in non-responsive subjects using a log-normal Bayesian linear model in the presence of left censored covariates. Statistics in Biopharmaceutical Research, 1(2), 137-148. C. Research Support Ongoing Research Support 1K99NR012217-01 Reeder (PI) 08/15/2010-06/30/2015 National Institutes of Health Timelines of Symptom Recognition, Interpretation, & Reporting in Heart Failure This study aims to 1) describe patterns of patient Recognition and Interpretation of HF symptoms, and factors that influence the timeliness in which patients Report (R-I-R) HF symptoms to health care providers and 2) establish the content and construct validity of a theoretical and clinically-based interview questionnaire on HF symptom recognition and interpretation and timeliness of reporting (R-I-R) HF symptoms. Role: Co-Mentor R01 NR009574 Thompson (PI) 08/01/2006-6/30/2011 National Institutes of Health The Impact of Quality End of Life Care in Nursing Homes The aims of this study are (1) to determine the influence on palliative care of communication, leadership, and teamwork, (2) examine the associations among structure (staffing), non-clinical (communication, leadership, teamwork) and clinical (palliative care) care processes and quality of end-of-life care, and (3) Explore Unruh and Wan’s expanded structure, process, and outcomes model in the context of nursing home palliative care. Role: Co-Investigator R01 HL085397 Smith (PI) 09/01/2006-05/31/2011 National Institutes of Health HF Group Clinic Appointments: Rehospitalization Prevention Clinical Trial The primary aim is to test the magnitude of effects of the intervention on the primary composite endpoint of HF rehospitalization or death and secondary endpoints of functional health status, quality of life and use of and satisfaction with health care services. Role: Statistician 1R01 NR011455 Williams (PI) 09/28/2010-06/30/2014 National Institutes of Health Changing Talk to Reduce Resistiveness to Dementia Care This study tests the effects of the Changing Talk (CHAT) communication training intervention for nursing home staff on the common and problematic resistiveness to care behaviors of nursing home residents with dementia. CHAT reduces nursing staff use of patronizing elderspeak communication, that was found to double the likelihood of resident resistiveness to care. Determination of CHATs effect on resident resistiveness to care will contribute evidence for nursing interventions to manage behavioral symptoms of dementia, to improve dementia care. Role: Co-Investigator P20 MD004805-01 Daley & Greiner (PI) 04/01/2010-3/31/2015 National Institutes of Health Center for American Indian Community Health (CAICH) The CAICH addresses health disparities among American Indians, who face some of the greatest health disparities of any racial/ethnic group in the US and who have not historically been well represented in medical research or education in the health professions. The center addresses a variety of health issues and focuses on two major health issues among American Indians, smoking and mammography. American Indians have the highest rates of smoking and rising incidence and disproportionate mortality for breast cancer. Role: Methods Core Director Dunton (PI) 01/01/2003-6/31/2011 American Nurses Association National Database of Nursing Quality Indicators (NDNQI) The National Database of Nursing Quality Indicators is established and maintained to: (1) provide benchmarking information on nursing-sensitive indicators to acute care hospitals for use in their quality improvement initiatives; and (2) monitor local and national trends in hospital nurse staffing to facilitate the American Nurses Association's Patient Safety, Nursing Quality initiative. Role: Statistician Completed Research Support Gajewski (PI) 05/12/2009-05/12/2010 KU Research Institute Bridging Grant for Integrated Analysis of Content and Construct Validity for Instrument Evaluation Basic research for building preliminary data that supports the NIH resubmission of “Integrated Analysis of Content and Construct Validity for Instrument Evaluation (IACCV).” The process of designing healthcare questionnaires can be lengthy and inefficient. IACCV aims to make this process more efficient by using statistical models to combine the information from experts and participants. Role: PI R01 NR009078-04 Smith (PI) National Institutes of Health Technological Home Care: Improving Care Giving 09/29/2005 - 06/30/2010 Specific aims of this study are to test the effects of a nursing intervention (FamTechCare) on family caregiver’s problem solving ability, participation in health care management, health status, depression, quality of life, and health care services costs. Role: Statistician R21 DA020489 Richter (PI) 07/20/2007-06/30/2010 National Institutes of Health Describing and Measuring Treatment in Drug Treatment The specific aims are (1) Identify why and how nicotine dependence services are offered, (2) Develop a Tobacco Treatment Survey (TTS) and adapt for tobacco a measure of organizational climate and structure, and (3) Conduct validity analyses and identify organizational attributes predictive of high-quality services. NIH NINR RO1 NR08028 Taunton (PI) 07/01/2002-04/30/2007 Care Planning Integrity & Nursing Home Resident Outcomes The overall aim of this study is to examine the integrity of the care planning process in nursing homes and demonstrate the relationship between care planning integrity and resident outcomes. Role: Statistician N/A Bott (PI) 07/01/2003-10/31/2008 Kansas Department of Aging Kansas Nursing Facility Project This provided to KDOA, nursing homes, and nursing home provider associations with information useful in improving resident care and health. The last two years of the study was the development of a instrument to measure the defining characteristics of a culture change nursing facility, and to evaluate the relationship between facility characteristics (e.g. staff turnover, ownership status, urban/rural location), survey deficiencies, and quality indicators with the constructs of culture change. Role: Investigator R01 HD047315 Carlson (PI) 04/04/2006-01/31/2011 National Institutes of Health DHA Supplementation and Pregnancy Outcomes To determine whether maternal RBC PL DHA can be significantly increased by supplementation, assess the effect of DHA supplementation on duration of gestation, evaluate adverse events in women and infants in the treated and placebo groups, evaluate the effect of maternal DHA supplementation on visual evoked potential acuity in infancy, and evaluate the effect of DHA supplementation on the development of fundamental measures of cognitive function in infancy. Role: Statistician