MOLECULAR GENETICS & BIOTECHNOLOGY
CHAPTER 12.1/12.2/12.3/12.4/13.2
NAME_______________________HR____
OBJECTIVES:
12.1 DNA: the GENETIC MATERIAL
1---IDENTIFY the scientists and their role leading to the discovery of DNA as genetic material
Franklin / Watson & Crick / Hershey & Chase / Avery & Griffith / Chargaff
*2---DIAGRAM / LABEL the basic structure of DNA
*3---EXPLAIN the function of DNA
12.2 REPLICATION of DNA
4---SUMMARIZE the role of the enzymes involved in the replication of DNA
DNA helicase / DNA polymerase / DNA ligase
5---EXPLAIN how leading and lagging strands are synthesized differently
12.3 DNA, RNA, and PROTEIN
*6---EXPLAIN how messenger RNA, ribosomal RNA and transfer RNA are involved in the transcription/translation of genes
7---SUMMARIZE the process by which the DNA code is made into a protein
8---EXPLAIN the meaning of CENTRAL DOGMA
12.4 GENE REGULATON and MUTATION
9---DETERMINE how mutations occur
10---IDENTIFY the various types of mutations
13.2 DNA TECHNOLOGY
11---RECOGNIZE how genetic engineering can improve human health
12---SUMMARIZE how gel electrophoresis is performed and its importance
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*13---COMPARE / CONTRAST the structure and function of RNA and DNA
UNIT VOCABULARY:
12.1 DNA: The Genetic Material
-double helix
-nucleotide
-nucleosome
-DNA
-Chargaff’s Rule
-RNA
12.3 DNA, RNA, and Protein
-RNA
-messenger RNA
-ribosomal RNA
-transfer RNA
-RNA polymerase
-codon / anti-codon
-transcription / translation
12.4 Gene Regulation and Mutation
-gene regulation
-mutation
-mutagen
13.2 DNA Technology
-genetic engineering
-genome
-gel electrophoresis
-recombinant DNA