Online Table 1. Variables Associated with Biological Sex and Included in the Genderrelated Score Calculation
Coefficient Estimate
p value
Primary earner status
-1.31
<0.0001
Personal income
-0.31
<0.0001
Number of hours per week doing
housework
0.06
<0.0001
Primary responsibility
housework
2.31
<0.0001
Level of stress at home
0.19
<0.001
BSRI masculinity score
-0.37
0.02
BSRI femininity score
0.71
<0.0001
for
doing
BSRI, Bem Sex Role Inventory
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Online Table 2. Values of Variables Included in the Gender-Related Score in Men and
Women
Mean (SD)
Men
Women
p value
471 (74)
117 (43)
<0.0001
50,000 to 69,999
30,000 to 49,999
<0.0001
11 (6)
14 (11)
<0.0001
165 (26)
205 (75)
<0.0001
Level of stress at home
(from 1 to 10)
4 (2)
5 (3)
<0.0001
BSRI masculinity score
(from 1 to 7)
5.0 (0.9)
4.8 (0.9)
0.002
BSRI femininity score
(from 1 to 7)
5.4 (0.9)
6.0 (0.8)
<0.001
Primary earner status, n (%)
Personal income, $
Number of hours per week
doing housework
Primary responsibility for
doing housework, n (%)
Adapted from Psychosomatic Medicine, 2015 Jun;77(5):517-26.
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Online Figure 1. Study Flow Diagram
Patients presenting with ACS, 18-55
years of age, fluent in English
and/or French, able to provide
informed consent (n=1443)
Refused to participate (n=230)
Men: 194
Women: 36
Included (n=1213)
Men: 885
Women: 328
Subpopulation with complete
baseline and 12-month follow-up
data at time of analysis (n=909)
Men: 636
Women: 273
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Appendix A Co-Investigators for GENESIS-PRAXY
Co-Principal Investigators
Louise Pilote (MD, MPH, PhD), Divisions of General Internal Medicine and Clinical
Epidemiology, McGill University Health Centre, Montréal, QC, Canada
Igor Karp (MD, MPH, PhD), Department of Epidemiology and Biostatistics, Schulich School of
Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
Co-Investigators
Simon L. Bacon (PhD), Concordia University and Research Centre, Hôpital du Sacré-Coeur de
Montréal, Montréal, QC, Canada
Jafna L. Cox (BA, MD, FRCPC, FACC), Department of Medicine and of Community Health and
Epidemiology, Dalhousie University, Halifax, NS, Canada
Kaberi Dasgupta (MD, MSc, FRCPC), Research Institute of the McGill University Health
Centre, Montréal, QC, Canada
Stella S. Daskalopoulou (MD, MSc, PhD), Research Institute of the McGill University Health
Centre, Montréal, QC, Canada
Mark J. Eisenberg (MD, MPH) Jewish General Hospital, McGill University, Montréal, QC,
Canada
James Engert (PhD), Research Institute of the McGill University Health Centre, Montréal, QC,
Canada
William Ghali (MD, MPH, FRCPC), University of Calgary, Calgary, AB, Canada
Karin Humphries (MBA DSc), University of British Columbia, Vancouver, BC, Canada
Nadia Khan (MD, MSc), University of British Columbia, Vancouver, BC, Canada
Kim L. Lavoie (PhD), University of Quebec at Montréal (UQAM) and Research Centre, Hôpital
du Sacré-Coeur de Montréal, Montréal, QC, Canada
Colleen Norris (RN, PhD), University of Alberta, Edmonton, AB, Canada
Doreen Rabi (MD, FRCPC, MS), University of Calgary, Calgary, AB, Canada
Derek So (MD, FRCPC, FACC), University of Ottawa Heart Institute, Ottawa, ON, Canada
Ken D. Stark (PhD), Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada
Vicky Tagalakis (MD, FRCPC, MSc), McGill University, Divisions of Internal Medicine and
Centre for Clinical Epidemiology and Community Studies, Jewish General Hospital, Montréal,
QC, Canada
Meytal Avgil (PhD), Research Institute of the McGill University Health Centre, Montréal, QC,
Canada
Roxanne Pelletier (PhD), Research Institute of the McGill University Health Centre, Montréal,
QC, Canada
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George Thanassoulis (MD, FRCPC) Research Institute of the McGill University Health Centre,
Montréal, QC, Canada
Avi Shimony (MD), Division of Cardiology, Soroka Medical Center, Ben Gurion University of the
Negev, Beer-Sheva, Israel
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Appendix B GENESIS-PRAXY Participating Centers
Site
Site PI
St Paul's Hospital, Vancouver, British Columbia, Canada
Krishan Ramanthan
Surrey Memorial Hospital, Surrey, British Columbia, Canada
Jan Kornder
Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary,
Alberta, Canada
Todd Anderson
/Doreen Rabi
University of Alberta and the Mazankowski Alberta Heart Institute,
Edmonton, Alberta, Canada
Colleen Norris
/Michelle Graham
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Derek So
McMaster University/Hamilton Health Sciences (General Site),
Hamilton, Ontario, Canada
Madhu Natarajan
McMaster University/Hamilton Health Sciences (Juravinski Site),
Hamilton, Ontario, Canada
Mike Rokoss
Ottawa Hospital, Ottawa, Ontario, Canada
Michele Turek
St Michael's Hospital, Toronto, Ontario, Canada
Asim Cheema
London Health Sciences Centre, London, Ontario, Canada
Shahar Lavi
The Scarborough Hospital, General Division, Scarborough, Ontario,
Canada
Sherryn Roth
Hôpital Général de Montréal, Montréal, Québec, Canada
Thao Huynh
Hôpital Royal Victoria, Montréal, Québec, Canada
Viviane Nguyen
Hôpital Général Juif-Sir Mortimer B. Davis, Montréal, Québec, Canada
Mark Eisenberg
Institut universitaire de cardiologie et de pneumologie de Québec
(Hôpital Laval), Québec, Québec, Canada
Julie Méthot
Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada
Michel Doucet
Citéde la Santé de Laval, Laval, Québec, Canada
Martine Montigny
Hôtel Dieu du Centre Hospitalier de l'Université de Montréal, Montréal,
Québec, Canada
Samer Mansour
Centre de santé et de services sociaux de la région de Thetford,
Thetford Mines, Québec, Canada
Claude Lauzon
CSSS Chicoutimi, Chicoutimi, Québec, Canada
Tomas Cieza
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Québec,
Canada
Michel Nguyen
CSSS Alphonse Desjardins (CHAU - Hôtel-Dieu de Lévis), Lévis,
Québec, Canada
François Grondin
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Queen Elizabeth II Health Science Centre, Halifax, Nova Scotia,
Canada
Jafna Cox
The New Brunswick Heart Centre Research Initiative and The New
Brunswick Heart Centre, New Brunswick, Canada
Peter Fong
Basset Healthcare, Cooperstown, New-York, USA
Dhananjai Menzies
Inselspital, University of Bern, Switzerland and Lausanne University
Hospital, Lausanne, Switzerland
Nicolas Rodondi
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