Job Description (1072) Post: Clinical Research Associate Responsible to: Professor of International Health, Clinical Sciences Summary of role: Mefloquine Cochrane review Systematic reviews are central to many global and national guideline in health care. The Cochrane Collaboration has developed methods, produced a large number of systematic reviews, and has contributed to more transparent approaches to policy making. UK Aid has supported The Cochrane Collaboration in low- and middle-income countries through a grant to a Consortium. The travellers’ review related to malaria chemoprophylaxis needs a new edition. This means drafting a new protocol to adopt new methods for carrying out the review. This will include examining for effectiveness and looking at observational studies of adverse effects. Outcome A completed final draft of a Cochrane review ready for copy editing evaluating adverse effects of mefloquine prophylaxis. Tasks To join a Cochrane team and develop a new protocol for adverse effects of mefloquine in travellers, including decisions about types of study to include and defining outcomes, in collaboration with the team. To consult with the methodological literature on adverse events and identify appropriate ways of extracting the data and assess risk of bias. To screen the search for studies and obtain full text of studies that may fulfil the inclusion criteria. To extract data and coordinate the double data extraction checking with a colleague. To assess risk of bias of the studies, describe them using a standard format, and summarise the results. To interpret the results with the team. To complete the SOF tables. To take into account editors comments and referee comments in completing the final submission for publication. Context You would work on a daily basis with dynamic and friendly Liverpool team. Your main points of contact will be, in alphabetical order: Paul Garner (joint co-ordinating editor), Dave Sinclair (joint co-ordinating editor), and Anne-Marie Stephani (managing editor). Others you will work with include Vittoria Lutje (information retrieval specialist), Martha Richardson (statistician), Deirdre Walshe, (assistant editor) and Phil Hinds (editorial assistant). The Consortium is organised in the Liverpool office through Paula Waugh. You will need to be able to work to deadlines. You will gain a wide spectrum of experience and skills in current methods of research synthesis. Document1 Person specifications Criteria Essential Desirable Education & Training Medical degree or possess another equivalent professional qualification Postgraduate qualification in epidemiology or related quantitative topic PhD Postgraduate teaching qualification Experience Critical appraisal of medical literature at postgraduate level Analysis of applied health services statistics or data for a dissertation or research publication demonstrating epidemiological and statistical ability Completed a systematic review of effects Author of a Cochrane review, and experienced in the software used Experience using GRADE Experienced in teaching health professionals at postgraduate level Track record in published research Excellent written and oral communications skills Working in a multidisciplinary team Skills & Abilities Clear evidence of critical insight into priority policy questions in international health relevant to infectious diseases Good communicator Ability to work as part of a team as well as independently Computer literate with working knowledge of MS Office applications Excellent time management and organisational skills Knowledge Systematic reviews and RCT trials basics Special Aptitude Initiative, and ability to organise own time Fastidious attention to detail. Able to work flexibly Enthusiastic approach to work Ability to work collaborative Interests Essential to be interested in developing countries and infectious disease problems Circumstances Needs to be able to travel overseas Document1 Demonstrable teaching skills to postgraduate students Experienced in editing and writing scientific articles Committed to capacity development