Biology November 16, 2012 11.3 Exploring Mendelian Genetics I. Independent Assortment A. Two-Factor Cross: F1 Mendel crossed true-breeding plants that produced only round yellow peas (genotype RRYY) with plants produced wrinkled green peas (genotype rryy) Result: F1 Offspring – all round and yellow peas Dominent alleles: round/yellow B. Two-Factor Cross: F2 Produced 556 seeds 1) 315 seeds - round/yellow 2) 32 seeds – wrinkled/green 3) 2 parental phenotypes 4) 209 seeds – combination phenotypes (alleles) – not found in either parent Independent Assortment Genes that segregate independently (seed shape/color) will not influence each other’s inheritance Ratio 9: 3: 3: 1 ***Principle of independent assortment states that genes for different traits can segregate independently during the formation of gamates. Independent assortment helps account for the many genetic variations observed in plants, animals, and other organisms. A Summary of Mendel’s Principles Form of basis of the modern science of genetics. 1) The inheritance of biological characteristics is determined by individual units known as genes. Genes are passes from parents to their offspring. 2) In cases in which two or more forms (alleles) of the gene for a single trait exist, some forms of the gene may be dominant and others may be recessive. 3) In most sexually reproducing organisms, each adult has two copies of each gene—one from each parent. These genes are segregated from each other when gametes are formed. 4) The alleles for different genes usually segregate independently of one another. II. Beyond Dominant and Recessive Alleles Exception to Mendel’s Experiment Some alleles are neither dominant nor recessive, and many traits are controlled by multiple alleles or multiple genes. Incomplete Dominance 1) One allele is not completely dominant over another 2) Heterozygous phenotype is somewhere in between the two homozygous phenotypes Codominance Both alleles contribute to the phenotype Ex. Allele can be both black and white feathers on a chicken – chicken will have a combination of both black and white feathers Multiple Alleles Genes that have more than two alleles **Can exist in a population not necessarily in an individual. Polygenic Traits “having many genes” Many traits are produced by the interaction of several genes III. Applying Mendel’s Principles Thomas Hunt Morgan used Mendel’s Principles to flies. He found that it worked not only with plants but all organisms.