List of Tables Table 1 Demographic characteristics for the male members of the cohort ................................. 9 Table 2 Mortality rates for the Gulf War veterans and comparison group relative to the Australian male population ........................................................................................10 Table 3 Mortality rates for the Gulf War veterans relative to the comparison group ...................10 Table 4 Cancer incidence rates for the Gulf War veterans and comparison group relative to the Australian male population ........................................................................................11 Table 5 Cancer incidence rates for the Gulf War veterans relative to the comparison group .....12 Table 6 Distribution of Gulf War veteran participants at baseline and at follow up by deployment ................................................................................................................................41 Table 7 Number of times exposures of interest noted in Ships’ Logs ........................................63 Table 8 Number of times exposures of interest noted in Reports of Proceedings ......................63 Table 9 Summary of environmental exposures reported in the Ships’ Medical Journals............64 Table 10 Summary of health outcome and health service use reported in the Ships’ Medical Journals ....................................................................................................................65 Table 11 Summary of reporting of vaccinations in the Ships’ Medical Journals .........................67 Table 12 Summary of reporting of preventive medication in the Ships' Medical Journals ..........68 Table 13 Health outcomes and environmental, chemical and medical exposure metrics based on Ship and other deployment groups.......................................................................72 Table 14 Recruitment outcomes for the Gulf War veterans and comparison group at follow up 74 Table 15 Comparison of participants with non-participants in the follow up study .....................77 Table 16 Characteristics for male participants at follow up ........................................................80 Table 17 ADF service characteristics for male participants at follow up ....................................81 Table 18 ADF Operations participants have deployed on for at least one month since Jan 1991 .................................................................................................................................81 Table 19 SF12 Physical and Mental Component Summary scores at follow up ........................84 Table 20 Association between Gulf War-deployment characteristics and SF12 Physical Component Summary sores at follow up in Gulf War veterans..................................85 Table 21 Association between Gulf War-deployment characteristics and SF12 Mental Component Summary sores at follow up in Gulf War veterans..................................85 Table 22 SF12 Physical and Mental Component Summary mean scores at baseline and follow up for participants who completed the SF12 at both time points................................86 Table 23 Prevalence of past-month symptoms at follow up.......................................................88 Table 24 Mean number of past-month symptoms endorsed at baseline and follow up ..............90 Table 25 Change in symptom prevalence between baseline and follow-up by study group.......92 Australian Gulf War Veterans’ Follow Up Health Study: Technical Report 2015 ix Table 26 Percentage of participants who reported a symptom at baseline which was persistent (repeated) at follow up, for the 20 most prevalent symptoms among Gulf War veterans ....................................................................................................................94 Table 27 Percentage of participants who did not report a symptom at baseline which was incident at follow up, for the 20 most prevalent symptoms among Gulf War veterans .................................................................................................................................95 Table 28 Association between Gulf War-deployment characteristics and multisymptom illness at follow up in male Gulf War veterans ..........................................................................98 Table 29 Prevalence of multisymptom illness at baseline and follow up ....................................98 Table 30 Persistent, remitted and incident cases of multisymptom illness among participants assessed at baseline and follow up ...........................................................................99 Table 31 Symptoms with low prevalence (<4%) in at least one dataset, excluded from exploratory factor analysis ......................................................................................100 Table 32 Factor loadings by study group based on follow-up symptom reporting....................102 Table 33 Comparisons of factors using Tucker’s Congruence Coefficient ...............................105 Table 34 Number and type of neuropathic symptoms at follow up ..........................................108 Table 35 Association between Gulf War deployment characteristics and average number of neuropathic symptoms at follow up in Gulf War veterans ........................................109 Table 36 Prevalence and Risk Ratios for fatigue, prolonged fatigue and chronic fatigue at follow up............................................................................................................................112 Table 37 Chalder Fatigue Scale (CFQ) fatigue scores and caseness by study group .............112 Table 38 Association between Gulf War-deployment characteristics and chronic fatigue at follow up in male Gulf War veterans ..................................................................................113 Table 39 Prevalence of prolonged fatigue and chronic fatigue at baseline and follow up ........113 Table 40 Persistent, remitted and incident cases of chronic fatigue among participants at baseline and follow up.............................................................................................114 Table 41 Sleeping pattern in the two weeks prior to follow up .................................................116 Table 42 Chronic Pain Grade at follow up ...............................................................................119 Table 43 Number of body areas of pain or tenderness in the seven days prior to follow up ....121 Table 44 Self-reported respiratory symptoms and medical conditions at follow up ..................124 Table 45 Association between Gulf War-deployment characteristics and Rome III IBS at follow up in male Gulf War veterans ..................................................................................127 Table 46 Difficulty fathering a pregnancy and treatment for infertility since January 1992 .......129 Table 47 Outcome of pregnancies fathered since 1992 ..........................................................130 Table 48 Live birth outcomes since 1992 ................................................................................130 Table 49 Activities and outcomes associated with participant’s two most recent injuries .........134 Table 50 Association between Gulf War-deployment characteristics and 12 month major depression at follow up in Gulf War veterans ..........................................................142 Australian Gulf War Veterans’ Follow Up Health Study: Technical Report 2015 x Table 51 Prevalence of 12 month major depression at baseline and follow up for participants who completed the CIDI at both time points ............................................................142 Table 52 Persistent, remitted and incident cases of 12 month major depression among participants who completed the CIDI at baseline and follow up ...............................143 Table 53 PCL total and subscale mean scores in male Gulf War veterans and comparison group members at follow up ..............................................................................................146 Table 54 Association between Gulf War-deployment characteristics and 12 month PTSD at follow up in male Gulf War veterans ........................................................................147 Table 55 Prevalence of 12 month PTSD at baseline and follow up for male participants who completed the CIDI at both time points ...................................................................147 Table 56 Persistent and new incident cases of 12 month PTSD among male Gulf War veterans and comparison group members who completed the CIDI at baseline and follow up ...............................................................................................................................148 Table 57 Association between Gulf War-deployment characteristics and 12 month alcohol disorders at follow up in Gulf War veterans .............................................................151 Table 58 Prevalence of 12 month alcohol disorders at baseline and follow up for male participants who completed the CIDI at both time points .........................................152 Table 59 Persistent and incident cases of 12 month Alcohol disorders among Gulf War veterans and comparison group members who completed the CIDI at baseline and follow up ...............................................................................................................................153 Table 60 CIDI-defined 12-month disorders, other than major depression, PTSD and alcohol disorder, for Gulf War veterans and comparison group participants at follow up .....154 Table 61 Association between Gulf War-deployment characteristics and GHQ-12 caseness at follow up in Gulf War veterans ................................................................................157 Table 62 Demoralization Scale median scores at the 10th, 25th, 50th, 75th and 90th percentiles 158 Table 63 Demoralization Scale median total score and subscale scores at follow up..............159 Table 64 EVAR-B mean total score and mean factor scores for participants at follow up ........161 Table 65 Medical problems or conditions which participants reported to be doctor-diagnosed or treated since January 2001 .....................................................................................163 Table 66 Events which happened because of a shortage of money ........................................166 Table 67 Participants convicted of a crime in a court of law ....................................................167 Table 68 Potentially traumatic events since January 2001 ......................................................167 Table 69 Health risk factors at follow up..................................................................................169 Table 70 Health risk factors at baseline and follow up for participants who were assessed at both time points.......................................................................................................172 Table 71 MOS Social Support scores by study group .............................................................173 Table 72 Description of linked DVA datasets ..........................................................................181 Table 73 Proportion of consenting participants with records in the linked DVA datasets .........183 Australian Gulf War Veterans’ Follow Up Health Study: Technical Report 2015 xi Table 74 Proportion of consenting participants with records in the linked Medicare datasets ..183 Table 75 Self-reported health professional consultations in the 12 months prior to follow up ..184 Table 76 General Practitioner consultations since 2001 as recorded on MBS.........................185 Table 77 DVA- and Medicare-MBS data on specialist consultations since 2001 .....................186 Table 78 Self-reported hospital service utilisation in the 12 months prior to follow up .............187 Table 79 DVA data on number of hospitalisations and length of stay since January 2007 ......188 Table 80 Principal diagnosis in participants who were hospitalised as recorded by DVA ........189 Table 81 Pharmaceuticals dispensed based on PBS and RPBS.............................................189 Table 82 Summary of disability claims from 1 January 2001 to 15 August 2012 .....................190 Table 83 Number of accepted disability claims, and legislation type, for participants who consented to DVA-data linkage ...............................................................................191 Table 84 Proportion of participants who had at least one successful claim under each of the broad SOP categories (VEA and MRCA claims only) ..............................................192 Table 85 DVA Treatment Card history for participants for the period 1 Jan 2001 to 15 Aug 2012 ...............................................................................................................................193 Table 86 Description of participants with at least one of MSI, chronic fatigue, or CIDI-defined 12month major depression, PTSD or alcohol use disorder at baseline........................196 Table 87 Health outcomes at follow up amongst participants with, and without, any of MSI, chronic fatigue, 12-month major depression, PTSD or alcohol use disorder at baseline ...............................................................................................................................198 Table 88 DVA Disability claims data for participants with, and without, any of MSI, chronic fatigue, 12 month major depression, PTSD or alcohol disorder at baseline .............199 Table 89 Health service use amongst participants with, and without, any of MSI, chronic fatigue, 12 month major depression, PTSD or alcohol disorder at baseline .........................200 Table 90 Association between use of PB during the Gulf War and health outcomes at follow up in Gulf War veterans ...............................................................................................205 Table 91 Association between vaccinations for the Gulf War deployment and health outcomes at follow up in Gulf War veterans ............................................................................206 Table 92 Association between anti-malarial tablets taken during the Gulf War deployment and health outcomes at follow up in Gulf War veterans..................................................207 Table 93 Association between exposure to pesticides during the Gulf War and health outcomes at follow up in Gulf War veterans ............................................................................207 Table 94 Association between intense smoke exposure during the Gulf War and health outcomes at follow up in Gulf War veterans ............................................................208 Table 95 Association between SMOIL exposure during the Gulf War and health outcomes at follow up in Gulf War veterans ................................................................................208 Table 96 Association between exposure to oil in water during the Gulf War and health outcomes at follow up in Gulf War veterans ............................................................................208 Australian Gulf War Veterans’ Follow Up Health Study: Technical Report 2015 xii Table 97 Association between dust exposure during the Gulf War and health outcomes at follow up in Gulf War veterans ..........................................................................................209 Table 98 Association between possible exposure to gastroenteritis outbreaks during the Gulf War and health outcomes at follow up in Gulf War veterans ...................................210 Table 99 Association between Gulf War deployment era and MSEQ score with health outcomes at follow up in Gulf War veterans ............................................................................211 Australian Gulf War Veterans’ Follow Up Health Study: Technical Report 2015 xiii