Note: This is the syllabus that I used several years ago, when we used the 3rd edition of
Hartwell. This will only be of use to you if you’ve chosen to use the earlier edition of Hartwell
rather than the current 4th edition. In that case, the relevant readings are listed below. Note
that topics may be covered in a different order. Just compare the topics with the current
syllabus.
L311 readings if using Hartwell, 3rd
edition
Lec
1
Date
Topic
Introduction
Reading
ch. 1, pp. 1-12
2
Mendelian genetics
ch. 2, pp. 13-24
3
ch. 2, pp. 24-29
4
Mendelian genetics, probability
problem set 1 posted
Mitosis
5
Meiosis
ch. 4, pp. 93-105
6
ch. 4, pp. 105-112
7
Sex linkage
problem set 2 posted
Pedigree analysis
8
Modifications of Mendelian ratios
ch. 3, pp. 45-56
9
ch. 3, pp. 56-66
10
Modifications of Mendelian ratios
problem set 3 posted
Environmental effects
11
Linkage mapping/recombination
ch. 5, pp. 123-127, 131-135
12
13
exam I
problem set 4 posted
Linkage mapping/recombination
ch. 5, pp. 135-142
14
Mitotic recombination
ch. 5, pp. 152-155
15
none
16
Somatic cell genetics
problem set 5 posted
Mutations
17
Mutations
18
19
Chromosome structure
problem set 6 posted
Chromosome structure
ch. 7, pp. 220-226, review
ch. 8, pp. 255-292
ch. 13, pp. 465-482
20
Chromosome abnormalities
ch. 14, pp. 489-508
21
Chromosome numbers
problem set 7 posted
ch. 14, pp. 516-525
ch. 4, pp. 81-93
ch. 2, pp. 30-36
ch. 3, pp. 66-71
ch. 7, pp. 207-220
1
22
Bacterial genetics
23
Viral genetics
24
25
exam II
problem set 8 posted
Maternal effect, Extranuclear inheritance
26
Recombinant DNA technology
27
Recombinant DNA technology
problem set 9 posted
Recombinant DNA technology
28
29
ch. 15, pp. 539-566
ch. 16, pp. 581-603, ch. 20,
p. 734-5
ch. 9, pp. 301-335, ch. 11,
pp. 408-419
31
Apps. of Recomb. DNA technology, RFLPs &
transgenics
Apps. of Recomb. DNA technology, gene therapy
& knockouts, problem set 10 posted
Analysis of Genomes
32
Analysis of Genomes
33
ch. 14, pp. 508-514
34
Transposons
problem set 11 posted
Experimental genetics
35
Cell cycle, apoptosis and cancer genetics
ch. 19, pp. 685-709
36
exam III
problem set 12 posted
Sex determination and dosage compensation
ch. 18, pp. 669-677
30
37
ch. 11, pp391-408
ch. 20, pp. 721-723
ch. 10, pp. 351-383
ch. 20, pp. 717-732
Thanksgiving break
Thanksgiving break
38
Developmental genetics, morphogens
39
Developmental genetics, cell-cell signaling
40
ch. 21, pp. 757-773
41
Population Genetics
problem set 13 posted
Population Genetics
42
Quantitative Genetics
ch. 21, pp. 773-781
43
to be announced
final exam
2
ch. 20, pp. 732-745,