SBI3U – Unit 2: Genetics Date: ____________________ 6.1 Beyond Mendel With advanced technology, scientists realized that patterns of inheritance are more complicated than Mendel proposed Patterns of inheritance observed by scientists that were ______________________________________________________________________________ Incomplete Dominance When neither allele for a gene completely conceals the presence of the other; Both alleles are ___________________________________, producing a ___________________________ (intermediate expression of a trait, looks like a ____________) E.g. flower colour in snapdragon plant E.g. familial hypercholesterolemia in humans p. 243 (top of textbook page) Example 1: Cross between a true-breeding red-flower plant and a true-breeding white-flower plant Red snapdragon x CRCR white snapdragon CWCW Cross between F1 offspring CRCW pink snapdragon CRCW x pink snapdragon CRCW SBI3U – Unit 2: Genetics Date: ____________________ Codominance Both dominant alleles are ______________________________ in a heterozygote at the ______________________ E.g. Hair colour in cattle E.g. Sickle cell anemia in humans (Heterozygote advantage, p. 244) Example 2: Cross between a true-breeding red bull and a true-breeding white cow Red Bull HrHr x White Cow Roan Calf HwHw Example of Codominance – Colours in Cows and Bulls Section 6.1 (Part 1) - Learning Check p. 244 #1-6 HrHw SBI3U – Unit 2: Genetics Date: ____________________ RECALL: Mendel experimented with pea plants; only 2 possible alleles tall vs. short; round vs. wrinkled; yellow vs. green; etc. What if there were multiple alleles????? Many traits in humans and other species are the result of interactions of ___________________ ____________________________________________________ A gene with more than two alleles is said to have __________________________ E.g. ______________________________________________________________________________ ______________________________________________________________________________ Q: What happens when genes have multiple alleles? A: When there are multiple alleles for a given characteristic, the alleles have a _____________________________________________ Hierarchy represented by capital letters with superscript numbers or letters Example 3: Rabbit Coat Colour DOMINANCE HIERARCHY Dominance Order Genotype C C AGOUTI C C , CCCch, CCCh, CCCc CHINCHILLA CchCch, CchCh, CchCc HIMALAYAN ChCh, ChCc ALBINO CcCc Agouti dominant over other colours Q: Cross between agouti CCCh & albino CcCc? F1 phenotypes: SBI3U – Unit 2: Genetics Date: ____________________ Blood Types A single gene determines a person’s blood type This gene determines what type of antigen protein, if any is attached to the cell membrane of __________________________________ What is an antigen protein? _____________________________________________________________________ Gene is designated, I and has 3 common alleles: IA , IB, i 4 different phenotypes (blood types), 6 genotypes Type A ___________________________________________________________________ Type B ___________________________________________________________________ Type AB _______________________________________ Type O ____________________________ Of the three alleles that determine blood type, one (_____) is recessive to the other two, and other two (____________________) are codominant Presence of allele IA, produces an ‘________________________’ Presence of allele IB, produces a ‘________________________ Presence of allele IA and IB, produces both ‘___________________ and ‘___________________’ Presence of allele i, produces ____________antigen SBI3U – Unit 2: Genetics Date: ____________________ Example 4: Blood Types Determine the possible phenotypes and genotypes of the F1 generation offspring of a parent with type AB blood and parent with type O blood. (Parent #1) IAIB x i i (Parent #2) Learning Check p. 247 #1-10 SBI3U – Unit 2: Genetics Date: ____________________ Environmental Effect on Inheritance Environmental conditions often affect the expression of traits. E.g. Some genes are influenced by temperature. Dark colour in Himalayan rabbits, is on the cooler parts of their bodies: the face, ears, tails, and feet. The dark colouring is the result of a gene that is only active below a certain temperature. One way to study the effect of the environment on expression of traits is to study genetically identical organisms placed in different surroundings. E.g. _____________________________________________________________________________________ _____________________________________________________________________________________ Continuous Variation Continuous variation _____________________________________________________________________________________ _____________________________________________________________________________________ These are traits for which the phenotypes vary gradually from one extreme to another. E.g. height and skin colour in humans, ear length in corn, and kernel colour in wheat. Continuous traits cannot be placed into discrete categories because they vary over a continuum. E.g. Height in humans varies over a wide range of values. People cannot be categorized as only short or tall. Traits that exhibit continuous variation are usually controlled by more than one gene and in some cases, involve several genes. Polygenetic Inheritance _____________________________________________________________________________________ _____________________________________________________________________________________ A group of genes that all contribute to the same trait is called a polygene. Each dominant allele contributes to the trait. Recessive alleles do not contribute to the trait. For skin colour the more dominant alleles a person has, ____________________________________________. Review Questions p. 250 #1-10