Appendix

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APPENDIX 1: SAMPLE SURVEY
Parameters used to Discontinue Dialysis in Acute Kidney Injury Recovery: A Survey of Unites States
Nephrologist.
1.How many years have you been in Nephrology?
a..Less than 2 years.
b. Between 2 to 5 years.
c. More than 10 years
2. How would you describe your practice?
a. University hospital
b. Private hospital with university affiliation
c. Private hospital
d. Other
3. How many patients with acute kidney injury do you see in a year?
a. less than 5 a year
b. between 5-10 a year
c. between 10-20 a year
d. more than 20 a year
4. Of those with acute kidney injury what percentage need dialysis?
a. less than 10%
b. between 10%-30%
c. more than 30
5. Does your hospital automatically calculate eGFR with serum chemistry?
a.yes
b.no
6. When weaning patients with AKI off dialysis select all that apply from the following parameters.
least important
important
more important
most important
*When weaning
patients with AKI off
dialysis select all that
Hyperkalemia
apply from the
Hyperkalemia
Hyperkalemia
Hyperkalemia
resolves: K+ is now following
resolves: K+ is now resolves: K+ is now resolves: K+ is now
less than
parameters.
less than 6.5meq/L. less than 6.5meq/L. less than 6.5meq/L.
6.5meq/L.
Hyperkalemia
important
more important
most important
resolves: K+ is now
less than 6.5meq/L.
least important
Metabolic
Metabolic Acidosis
Acidosis resolves.
resolves.
least important
Metabolic
Acidosis resolves.
important
Metabolic
Acidosis resolves.
more important
Metabolic
Acidosis resolves.
most important
The patient is
The patient is not not oliguric any
oliguric any more. more. least
important
The patient is
not oliguric any
more. important
The patient is
not oliguric any
more. more
important
The patient is
not oliguric any
more. most
important
The patient is
not volume
overloaded any
more. important
The patient is
not volume
overloaded any
more. more
important
The patient is
not volume
overloaded any
more. most
important
Pre-dialysis
serum creatinine is
lower despite the
same dose of
dialysis. more
Pre-dialysis
serum creatinine is
lower despite the
same dose of
dialysis. most
The patient is
The patient is not not volume
volume overloaded overloaded any
any more.
more. least
important
Pre-dialysis serum
Pre-dialysis
Pre-dialysis
creatinine is lower serum creatinine is
serum creatinine is
despite the same lower despite the
lower despite the
dose of dialysis.
same dose of
same dose of
dialysis. least
least important
important
more important
most important
important
dialysis. important
important
important
Pre-dialysis serum
blood urea
nitrogen is lower
despite the same
dose of dialysis.
Pre-dialysis
Pre-dialysis
serum blood urea serum blood urea
nitrogen is lower
nitrogen is lower
despite the same
despite the same
dose of dialysis. least dose of dialysis.
important
important
Pre-dialysis
serum blood urea
nitrogen is lower
despite the same
dose of dialysis.
more important
Pre-dialysis
serum blood urea
nitrogen is lower
despite the same
dose of dialysis.
most important
Clinical
improvement
occurs: Blood
pressure stabilizes
without pressors.
Clinical
improvement
occurs: Blood
pressure stabilizes
without pressors.
least important
Clinical
improvement
occurs: Blood
pressure stabilizes
without pressors.
more important
Clinical
improvement
occurs: Blood
pressure stabilizes
without pressors.
most important
Respiratory
parameters
improve.
Respiratory
Respiratory
Respiratory
Respiratory
parameters improve. parameters improve. parameters improve. parameters improve.
least important
important
more important
most important
Cognition
improves.
Cognition
improves. least
important
Clinical
improvement
occurs: Blood
pressure stabilizes
without pressors.
important
Cognition
Cognition
improves. more
improves. important
important
Cognition
improves. most
important
7. Would you continue to dialyze a patient with a persistently elevated potasssium even if the serum
creatinine is now 1.5-2 mg/dL?
a. Yes
b. No
8. Before stopping dialysis in a patient with AKI, do you get a creatinine clearance with a timed urine
collection?
a. Yes proceed to the next question .
b. No skip the next question.
9. If you do a timed creatinine clearance to determine if you should stop dialysis in a patient with AKI
due to renal function recovery select all that apply.
can safely stop
dialysis
can stop and see if less comfortable
further dialysis
with stopping
needed
dialysis
cannot stop dialysis
*If you do a
timed creatinine
clearance to
determine if you
less than
less than
should stop dialysis
less than 12ml/min in a patient with AKI 12ml/min can stop 12ml/min less
and see if further
comfortable with
due to renal function
dialysis needed
stopping dialysis
recovery select all
that apply. less than
12ml/min can safely
stop dialysis
less than
12ml/min cannot
stop dialysis
between 1220ml/min
between 12between 12between 1220ml/min can stop 20ml/min less
20ml/min can safely
and see if further
comfortable with
stop dialysis
dialysis needed
stopping dialysis
between 1220ml/min cannot
stop dialysis
more than
20ml/min
more than
more than
more than
20ml/min can stop 20ml/min less
20ml/min can safely
and see if further
comfortable with
stop dialysis
dialysis needed
stopping dialysis
more than
20ml/min cannot
stop dialysis
10. You would stop dialysis in the following scenarios
True
False
Hyperkalemia
Hyperkalemia resolves and patient is
*You would stop dialysis in the
resolves and
volume overloaded. False
patient is volume following scenarios Hyperkalemia resolves
True
overloaded.
False
and patient is volume overloaded. True
Hyperkalemia
resolves and the
Hyperkalemia resolves and the
creatinine
creatinine clearance is about 10ml/min
clearance is about True
10ml/min
Hyperkalemia resolves and the
creatinine clearance is about 10ml/min
False
Hyperkalemia
Hyperkalemia resolves and acidosis is
Hyperkalemia resolves and acidosis is
resolves and
present False
acidosis is present present True
Hyperkalemia
resolves and the
patient is septic
and catabolic
Hyperkalemia resolves and the
patient is septic and catabolic True
Hyperkalemia resolves and the
patient is septic and catabolic False
11. Oliguria resolves and you are considering stopping dialysis in the setting of AKI. Which of the
following would make you continue dialysis.
No
Hyperkalemia is
present
Unlikely
Yes
*Oliguria
resolves and you are
considering stopping
dialysis in the setting
of AKI. Which of the
Hyperkalemia is
Hyperkalemia is
Hyperkalemia is
following would
present Unlikely
present Likely
present Yes
make you continue
dialysis.
Hyperkalemia is
present No
Metabolic
Metabolic acidosis
acidosis
is present
is present
No
Creatinine Clearace
Likely
Creatinine
Metabolic
acidosis is present
Unlikely
Metabolic
acidosis is present
Likely
Metabolic
acidosis is present
Yes
Creatinine
Creatinine
Creatinine
No
is 10ml/min
Unlikely
Yes
Clearace is 10ml/min Clearace is 10ml/min Clearace is 10ml/min Clearace is 10ml/min
No
Unlikely
Likely
Yes
Sepsis is present
Sepsis is present
No
Cognition has not
Cognition has
improved
not improved No
Sepsis is present
Sepsis is present
Sepsis is present
Unlikely
Likely
Yes
Cognition has
not improved
Unlikely
Respiratory
Respiratory failure
Respiratory
failure is present
is present
failure is present No
Unlikely
Congestive Heart
Failure is present
Likely
Congestive
Heart Failure is
present No
Congestive
Heart Failure is
present Unlikely
Cognition has
Cognition has
not improved Likely not improved Yes
Respiratory
failure is present
Likely
Respiratory
failure is present Yes
Congestive
Heart Failure is
present Likely
Congestive
Heart Failure is
present Yes
12. Getting patients off dialysis for AKI takes longer in the following scenarios, pick all that apply
No
Unlikely
*Getting
patients off dialysis
for AKI takes longer
Age over 65
Age over 65 years in the following
years Unlikely
scenarios, pick all
that apply Age over
65 years No
Pre-existing CKD
Pre-existing CKD
No
Pre-existing
Pre-existing
Likely
Yes
Age over 65
years Likely
Age over 65
years Yes
Pre-existing CKD
Pre-existing CKD
Pre-existing CKD
Unlikely
Likely
Yes
Pre-existing
Pre-existing
Pre-existing
No
Unlikely
Likely
Yes
Congestive Heart
Failure
Congestive Heart
Failure No
Congestive Heart
Failure Unlikely
Congestive Heart
Failure Likely
Congestive Heart
Failure Yes
Multi-organ failure
Multi-organ
failure No
Multi-organ
failure Unlikely
Multi-organ
failure Likely
Multi-organ
failure Yes
13. After taking a patient off dialysis for AKI with improvement, you had to restart dialysis in a 28 day
period for - pick all that apply.
No
Unlikely
Likely
Yes
Recurrence of
sepsis Likely
Recurrence of
sepsis Yes
Recurrence of
sepsis
*After taking a
patient off dialysis
for AKI with
improvement, you
had to restart
Recurrence of
dialysis in a 28 day sepsis Unlikely
period for - pick all
that apply.
Recurrence of sepsis
No
Recurrent
nephrotoxin
exposure like
intravenous
contrast
Recurrent
Recurrent
Recurrent
Recurrent
nephrotoxin
nephrotoxin
nephrotoxin
nephrotoxin
exposure like
exposure like
exposure like
exposure like
intravenous contrast intravenous contrast intravenous contrast intravenous contrast
No
Unlikely
Likely
Yes
Recurrent
nephrotoxin
exposure like
antibiotics
Recurrent
nephrotoxin
exposure like
antibiotics No
Recurrence of
Recurrence of
renal disease like renal disease like
Recurrent
Recurrent
nephrotoxin
nephrotoxin
exposure like
exposure like
antibiotics Unlikely antibiotics Likely
Recurrent
nephrotoxin
exposure like
antibiotics Yes
Recurrence of
renal disease like
Recurrence of
renal disease like
Recurrence of
renal disease like
No
Unlikely
Likely
Yes
vasculitis or renal vasculitis or renal
obstruction
obstruction No
vasculitis or renal vasculitis or renal
obstruction Unlikely obstruction Likely
vasculitis or renal
obstruction Yes
Recurrence of
Congestive Heart
Failure
Recurrence of
Congestive Heart
Failure Unlikely
Recurrence of
Congestive Heart
Failure Likely
Recurrence of
Congestive Heart
Failure Yes
Dialysis was
stopped too early
Likely
Dialysis was
stopped too early
Yes
Recurrence of
Congestive Heart
Failure No
Dialysis was
Dialysis was
Dialysis was
stopped too early stopped too early No stopped too early
Unlikely
14. After being taken off dialysis, it may need to be re-started in a 28 day period due ot - pick all that
apply:
No
Unlikely
Likely
Yes
*After being
taken off dialysis, it
may need to be reRecurrence of the started in a 28 day
Recurrence of
Recurrence of
initial problem
period due ot - pick the initial problem the initial problem
causing AKI.
all that apply:
causing AKI. Unlikely causing AKI. Likely
Recurrence of the
initial problem
causing AKI. No
Recurrence of
the initial problem
causing AKI. Yes
Dialysis was
Dialysis was
Dialysis was
stopped too eary. stopped too eary. Nostopped too eary.
Unlikely
Dialysis was
stopped too eary.
Yes
Dialysis was
stopped too eary.
Likely
eGFR continued
eGFR continued
eGFR continued to
eGFR continued
eGFR continued
to
decline
for
to
decline
for
decline for unclear to decline for
to decline for
unclear reasons.
unclear reasons.
reasons.
unclear reasons. No
unclear reasons. Yes
Unlikely
Likely
15. Of those who get dialysis for AKI in the hospital select all that apply
No
>50% die
unlikely
*Of those who
get dialysis for AKI in
>50% die
the hospital select all
unlikely
that apply >50% die
No
20 to 50% die
20 to 50% die
No
5-20 % die
5-20 % die No
<5% die
<5% die No
20 to 50% die
unlikely
5-20 % die
unlikely
<5% die unlikely
likley
Yes
>50% die likley
20 to 50% die
likley
>50% die Yes
20 to 50% die
Yes
5-20 % die likley
5-20 % die Yes
<5% die likley
<5% die Yes
16. Of those that start dialysis for AKI most will - select all that apply
No
unlikely
likely
Yes
*Of those that
start
dialysis for AKI
Need to
Need to
Need to
Need to continue
most will - select all continue dialysis and continue dialysis and continue dialysis and
dialysis and will
that apply Need to will not be able to will not be able to will not be able to
not be able to
come off dialysis.
come off dialysis.
come off dialysis. continue dialysis and come off dialysis.
will not be able to unlikely
likely
Yes
come off dialysis. No
Many will come
Many will come
Many will come
Many will come
Many will come off
but will have CKD off but will have CKD off but will have CKD off but will have CKD off but will have CKD
No
unlikely
likely
Yes
Many will have to
Many will have
Many will have
Many will have
Many will have
be followed up
even if present
serum creatinine
normalizes.
No
unlikely
likely
Yes
to be followed up
even if present
serum creatinine
normalizes. No
to be followed up
even if present
serum creatinine
normalizes. unlikely
to be followed up
even if present
serum creatinine
normalizes. likely
to be followed up
even if present
serum creatinine
normalizes. Yes
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