MIAMI-DADE COUNTY PUBLIC SCHOOLS Student BYOD Resource Page BIOLOGY I HONORS TOPIC XIX: GENETICS – Review Heredity: Mendelian Genetics Course Code: 200032001 Pacing Date Traditional 6 days Block ESSENTIAL CONTENT OBJECTIVES A. Law of Segregation and Independent Assortment (16.1) Use Mendel's laws of dominance, segregation and 1. Experiments independent assortment to analyze patterns of a. Formation of Gametes inheritance. (ALD) b. Role of fertilization Analyze, and predict inheritance patterns caused by c. Genes and alleles various modes of inheritance. (ALD) d. Genotype vs. Phenotype Use Punnett squares to solve problems involving e. Generations: P, F1, F2 monohybrid & dihybrid crosses. 2. Mendel’s Principles Use Punnett squares to solve problems using other a. Principle of Dominance forms of inheritance (may assess P and F1 generation) b. Principle of Segregation Describe genetic drift affects variation in a population c. Principle of Independent Assortment and its effect on evolution. 3. Dominant/Recessive Inheritance Explain how mutations in the DNA sequence may or may not result in a phenotypic change. B. Other Patterns of Inheritance (16.2) Relate mutation and genetic recombination to an 1. Incomplete dominance increase in genetic variation. (ALD) 2. Codominance Predict the possible consequences of a mutation on and 3. Sex Linkage describe how these variations affect evolution. 4. Multiple Alleles Identify the gene or chromosomal mutation involved in 5. Polygenic Traits human disorders such as Down’s syndrome, 6. Genes and Environment Huntington’s disease, Hemophilia and Tay-Sachs disease. C. Punnett Squares (16.1) Recognize disorders caused by sex-linked genes and 1. Monohybrid Cross predict outcomes using Punnett squares. 2. Dihybrid Cross Identify chromosomal disorders by looking at a karyotype. D. Predict and Analyze Pedigrees Explain the significance of genetic factors to health from 1. Creation and Interpretation of Pedigrees the perspectives of both individual and public health. 2. Karyotypes All Mathematics and Language Arts benchmarks must be incorporated into the instruction throughout E. Genetic Drift and Gene Flow (15.14) the year, where applicable. Division of Academics – Department of Science Third Nine Weeks 3 days 02-29-16 to 03-09-16 02-29-16 to 03-09-16 INSTRUCTIONAL TOOLS Core Text Book: Chapter 11:1, 2, and 3, Chapter 14:1 and 2, Chapter 17:1 Vocabulary: Genetics, Probability, Punnett square, Trait, Gene, Factor, Allele, Dominant, Recessive, Gamete, Homozygous, Heterozygous, Phenotype, Genotype, Principle of Dominance, Segregation, Independent Assortment, Multiple allele, Polygenic trait, Crossing over, Mutation, Genetic drift, Gene Flow, Gene, Incomplete dominance, Codominance, DNA, Sex-linked gene, Sex chromosome, Karyotype, Pedigree. Technology: 1. Glencoe: Virtual Lab: Punnett Squares 2. NDSU: Mendelian Genetics 3. EDC.org: Web Lab: Incomplete Dominance and Codominance 4. Chapter 11 Mystery: Green Parakeets 5. Untamed Science Video: Genetics Takes Root 6. Chapter 11.2: Interactive Art: Punnett Squares 7. Chapter 14 Mystery: The Crooked Cell 8. Probability of Inheritance -anthro.palomar.edu/mendel 9. Advanced Genetics Crosses: -Biologycorner 10. Punnett Squares –Monohybrid, Dihybrid, and SexLinked Crosses 11. Bozeman Podcast: Mendelian Genetics 12. Bozeman Podcast: Genetics 13. Bozeman Podcast: Genotypes and Phenotypes 14. TED Talks: How Mendel’s Pea Plants Helped Us Understand Genetics 15. Khan Academy: Introduction to Heredity 16. Khan Academy: Punnett Square Fun 17. HippoCampus Biology: The Mendelian Model of Inheritance: Summary 18. HippoCampus Biology: Mendel's Law of Segregation 19. HippoCampus Biology: Mendel's Law of Independent Assortment 20. HippoCampus Biology: Mendel's Experiments 21. Edgenuity 22. Extended Learning Modules Page 1 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Student BYOD Resource Page BIOLOGY I HONORS Course Code: 200032001 Mouse Genetics (One Trait) Mouse Genetics (Two Traits) SC.912.L.16.2 Human Karyotyping Chicken Genetics Inheritance Video Standard: SC.912.L.14.6 Science Content Collection Obesity and Genetics What Are Nutritional Disorders? Exploring Nutritional Disorders Multifactorial Disorders Risk Factors for Breast Cancer Interpreting Epidemiological Data Air Pollution and Public Health Water in Manila's Poor Communities Chemicals in the Environment Introduction to Waste Everyday Water Pollution PCBs: What They Are and Where They Come From Evolution in Action: Genetic Drift Genetic Drift Evolution in Action: Gene Flow 5 Factors That Contribute to Gene Pool Changes Over Time Audio Evolution: Sources of Variability: Genetic Drift Evolution: Sources of Genetic Variability: Gene Flow Division of Academics – Department of Science Third Nine Weeks Contamination and Human Health Anthrax Invisible Poison Wastewater Germs Contaminated Eggs Food Safety Human Body, Human Health Video Standard: SC.912.N.15.14 Page 2 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Student BYOD Resource Page BIOLOGY I HONORS Course Code: 200032001 Video Standard: SC.912.N.15.15 Audio Standard: SC.912.L.16.1 Video Standard: SC.912.L.16.1 Audio Video Standard: SC.912.L.16.2 Audio Division of Academics – Department of Science Third Nine Weeks Evolution in Action Natural Selection and Mutations Genetics Evolution: Sources of Variability: Recombination Garden Pea Reproduction and CrossPollination The Law of Segregation The F² Generation The Law of Independent Assortment Biology Concepts for Students: Genetics: Introduction Hybrids Mendel's Experiments Principle of Dominance Principle of Segregation Genetics: Working with a Punnett Square Genetics: Using Probability as an Alternative to Punnett Mendel's Hypotheses Review Punnett's Square Inheritance Patterns The Hardy-Weinberg Equilibrium Biologix: The Hardy-Weinberg Principle Gregor Mendel's Reseach on Pea Plants and His Development of Theories of Inheritance Genes, Chromosomes, and Alleles Punnett's Square Patterns of Inheritance Survey and Data Analysis: Dominant and Recessive Traits for Hairline, Thumb, and Earlobes Research Results Introduction: Sex-Linked Inheritance Research on the Genetic Make-up of the Fruit Fly Drosophila Karyotype: A Key to the Study of SexLinked Inheritance Heredity: Problems Using Sex Chromosomes and Sex Linkage Inherited Human Traits and Patterned Sex-Linked Inheritance Color Blindness Organizing Information About SexLinked Inheritance in Pedigree Charts Hemophylia Closing Remarks: Sex-Linked Inheritance Sex-Linked Traits Single Gene Disorders Heredity: Sex Linkage Punnett's Contributions to Genetics: Development of a Tool to Predict the Outcomes of Matings Introduction: Dihybrid Crosses Simulating a Dihybrid Cross Breeding White Songbird Canaries Through a Dihybrid Cross Probability Possible Combinations of Human Alleles Incomplete Dominance in Snapdragons Incomplete Dominance in Humans and Plants Reviewing Key Terms That Relate to Patterns of Inheritance Multiple Alleles and Co-Dominance in Human Blood Types Rabbit Breeding Page 3 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Student BYOD Resource Page BIOLOGY I HONORS Course Code: 200032001 Video Standard: HE.912.C.1.7 Audio Video The Role of Genes Mendel's Laws of Inheritance Inheritance Patterns Heredity: How Our Parents' Genes Affect Us Basic Facts About Cancer Obesity Diabetes Is Tone Deafness Hereditary? Can Your Grandfather's Diet Shorten Your Life? Hunting Down the Genes Involved in Disease DNA and the Genetics of Cancer Genetic Disease Families and Genetic Disease Genetic Case Study: Addison's Disease Risk Factors for Heart Disease DNA Screening High & Low Risks for Cancer High & Low Risks for Cardiovascular Disease High & Low Risks for Diabetes Cystic Fibrosis Gene Therapy Offers New Hope to Cancer Patients Researchers Discover Genes Linked to Deadly Cancers No Interest in the Gym? It May Be Genetic Researchers: "Junk DNA" Plays Critical Role Critics Unconvinced of Genetically Modified Salmon Genetic Test Can Help Tailor Breast Cancer Treatment Changing Mosquito Genes Gene May Predict Lung Cancer in Smokers Six Million New Genes Identified in Marine Organisms DNA Testing Connects Unlikely Cousins Scientists Discover New Gene That Could Help Pinpoint Cause of Alzheimer's Disease Searching Genes, Genome, for Health Predispositions Mapping the Human Genome "Fountain of Youth" Anti-Aging Gene Found in Earthworms "Designer Babies"? New Processes Let Parents Select Baby's Sex Division of Academics – Department of Science Third Nine Weeks Page 4 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Learning Goals BIOLOGY I HONORS Course Code: 200032001 SC.912.L15.14: Discuss mechanisms of evolutionary change other than natural selection such as genetic drift and gene flow. (Level 3: Strategic Thinking & Complex Reasoning) SCALE LEARNING PROGRESSION I am able to assess the mechanisms resulting in evolutionary change. Using a given scenario, predict the effect of genetic drift, nonrandom mating, and gene flow on a population. I am able to summarize the scientific mechanisms resulting in evolutionary change. Use a graphic organizer to describe genetic drift, nonrandom mating, and gene flow with specific examples from nature. I am able to recognize some of the scientific mechanisms resulting in evolutionary change. Distinguish between genetic drift, nonrandom mating, and gene flow. I am able to recognize one scientific mechanism that results in evolutionary change. Define genetic drift, nonrandom mating, or gene flow. I am able to recognize life changes over time. Score/Step 5.0 Score/Step 4.0 Score/Step 3.0 Target (Learning Goal) Score/Step 2.0 SAMPLE PROGRESS MONITORING AND ASSESSMENT ACTIVITIES Score/Step 1.0 Division of Academics – Department of Science Third Nine Weeks Page 5 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Learning Goals BIOLOGY I HONORS Course Code: 200032001 SC.912.L15.15: Describe how mutation and genetic recombination increase genetic variation. (Level 3: Strategic Thinking & Complex Reasoning) SCALE LEARNING PROGRESSION I am able to relate mutation and genetic recombination to an increase in genetic variation. Design an experiment that would test the impact of increased genetic variation on a population and relate the cause of increased genetic variation to mutation or genetic recombination. I am able to relate how mutation and genetic recombination increase genetic variation. Use a graphic organizer to show how mutation and genetic recombination leads to an increase in the genetic variation of a population. I am able to relate that mutation and genetic recombination increase genetic variation. Distinguish between mutation and genetic recombination and relate each to increased genetic variation in a population. I am able to recall that mutation and genetic recombination increase genetic variation. Identify causes of increased genetic variation in a population. I am able to understand there is genetic variation in a population. Score/Step 5.0 Score/Step 4.0 Score/Step 3.0 Target (Learning Goal) SAMPLE PROGRESS MONITORING AND ASSESSMENT ACTIVITIES Score/Step 2.0 Score/Step 1.0 Division of Academics – Department of Science Third Nine Weeks Page 6 of 7 MIAMI-DADE COUNTY PUBLIC SCHOOLS Learning Goals BIOLOGY I HONORS Course Code: 200032001 SC.912.L16.1: Use Mendel’s laws of segregation and independent assortment to analyze patterns of inheritance. (Cognitive Complexity: Level 3: Strategic Thinking & Complex Reasoning) SC.912.L16.2: Discuss observed inheritance patterns caused by various modes of inheritance, including dominant, recessive, codominant, sex-linked, polygenic, and multiple alleles. (Cognitive Complexity: Level 3: Strategic Thinking & Complex Reasoning) SCALE Score/Step 5.0 Score/Step 4.0 LEARNING PROGRESSION I am able to use Mendel’s laws to analyze patterns of inheritance. I am able to analyze and predict inheritance patterns caused by various modes of inheritance. Given a pedigree chart, analyze the specific mode of inheritance. Using both parental phenotypes create an offspring. I am able to relate use Mendel’s laws to analyze patterns of inheritance. I am able to predict inheritance patterns caused by various modes of inheritance. I am able to identify inheritance patterns caused by various modes of inheritance, including Mendel’s laws. Given two parental phenotypes or genotypes, use a Punnett square to predict potential offspring outcomes for any of the modes of inheritance listed below. I am able to identify inheritance patterns caused by various modes of inheritance. Use a graphic organizer to differentiate between the following word pairs—dominant/recessive, phenotype/genotype, homozygous/heterozygous—as well as the meanings of the following modes of inheritance: codominance, incomplete dominance, polygenic, sex-linked, and multiple alleles. I am able to recall that inheritance is the passage of genetic material from parent to offspring, and that Punnett squares can be used to predict offspring inheritance outcomes. Score/Step 3.0 Target (Learning Goal) Score/Step 2.0 Score/Step 1.0 SAMPLE PROGRESS MONITORING AND ASSESSMENT ACTIVITIES Division of Academics – Department of Science Third Nine Weeks Given an offspring outcome (percent, ratio, or fraction), determine the parents’ genotype and phenotype and identify the mode of inheritance. Page 7 of 7