Workshop: High-Impact Research to Change Lives November 7, 2014 Learning Objectives: Participants should leave energized by progress occurring in MS research, and should be able to inspire others by explaining in simple terms several promising areas of research and the Society’s role in driving progress. About Our Panelists Mark Allegretta, Ph.D. Associate Vice President of Commercial Research, National MS Society Mark’s responsibilities include providing leadership and direction for the Society’s commercial research programs and portfolio, including partnerships developed through Fast Forward. He joined the Society in 2014 with 28 years of experience in biotechnology and pharmaceutical operations. Most recently, he was President, Chief Scientific Officer and Co-founder of BioMosaics in Burlington, Vermont, where he dealt with all aspects of cancer biomarker development, licensing deals and business partnerships. Mark earned his Bachelor’s degree from Hartwick College and his PhD in Cellular and Molecular Biology from the University of Vermont. He was the recipient of a National MS Society postdoctoral fellowship at Stanford University. Benjamin Deneen, PhD Associate Professor, Center for Stem Cell and Regenerative Medicine Baylor College of Medicine Ben earned his PhD in Molecular Biology at the University of California, Los Angeles, and did a postdoctoral research fellowship at the California Institute of Technology. Ben’s research interests focus on mechanisms involved in nerve degeneration and repair in a variety of conditions including MS. His laboratory studies gene mechanisms that control the generation and differentiation (specialization) of glial cells including myelin-making cells. He studies myelin repair and factors that block myelin repair. He also studies the role of a brain cell type called astrocytes in disease. As he notes, “While glial cells constitute roughly 90% of the central nervous system, and are associated with numerous neurological disorders and malignancies, the mechanisms that control their development and diversity remain shrouded in mystery.” Ben serves as a volunteer scientific peer reviewer for the National MS Society, and he will be participating on a panel featured during the Research Luncheon later today. Karen Lee, PhD Vice-President of Research, Multiple Sclerosis Society of Canada Karen oversees day-to-day research operations and provides leadership to a broad range of initiatives set in motion to find the cure for MS and improve the quality of life for people who are affected by MS. She serves as the Managing Director for the endMS Research and Training Network, providing leadership to regional training centres across Canada and ensuring effective implementation of programs to attract and retain MS researchers. She also serves on the Scientific Steering Committee of the international Progressive MS Alliance. Her PhD degree is in Cellular Molecular Medicine from the University of Ottawa. Michael Racke, M.D. Professor, Department of Neurology, The Ohio State University An international leader in neurological sciences, Mike is a distinguished scholar known for his research in immunology and multiple sclerosis. He serves on the executive committee of the Multiple Sclerosis Section of the American Academy of Neurology and the National MS Society’s Research Programs Advisory Committee. He has previously served on scientific advisory committees for the National Multiple Sclerosis Society and the National Institutes of Health. He has received the prestigious Harry Weaver Neuroscience Scholarship from the National MS Society and the Young Investigator in Multiple Sclerosis Award from the American Academy of Neurology Education and Research Foundation. Mike is investigating the pathogenesis of MS with an eye toward developing new and better therapies. Mike is being inducted into the Volunteer Hall of Fame as a researcher – an honor he previously received as an MS physician with the Lone Star Chapter. Questions? Cathy Carlson, AVP of Research Information cathy.carlson@nmss.org Additional Resources Online Research Champion Video and Training Module: http://www.nationalmssociety.org/Research/Research-We-Fund/How-We-Fund-Research-NOWCampaign/Become-a-Research-Champion Research News and Progress: http://www.nationalmssociety.org/Research/Research-NewsProgress Learn About Research the Society Funds to Stop MS, Restore Function and End MS Forever: http://www.nationalmssociety.org/Research/Research-We-Fund Research in Progressive MS: http://www.nationalmssociety.org/Research/Research-NewsProgress/Progressive-MS-Research Progressive MS Alliance: http://www.endprogressiveMS.org Nervous System Repair: http://www.nationalmssociety.org/Research/Research-WeFund/Restoring-What-s-Been-Lost/Repairing-Damaged-Tissues Wellness and Lifestyle Research: http://www.nationalmssociety.org/Research/Research-NewsProgress/Diet/Wellness-and-Lifestyle Driving Commercial Research: http://www.nationalmssociety.org/Research/Research-WeFund/Driving-Solutions/Driving-Commercial-Progress The NOW Campaign to Move Research Forward Faster: http://www.nationalmssociety.org/NationalMSSociety/media/MSNationalFiles/Brochures/MSNOW-Brochure_2014.pdf