Master of Science Programme in Molecular Biology
Degree Designation M.Sc. (Molecular Biology and Bioinformatics)
Curriculum Structure
Required Courses
Elective Courses not less than
Thesis
Total
Plan A1
36
36
Plan A2
8
4
24
36
Courses Description
Plan A
Thesis
319 - 692
Thesis
To equip candidate for the Master of Science with some
research skills and experience in molecular biology and
bioinformatics under supervision of a thesis committee
Plan B
Required Courses
318 - 501 Molecular Biology for Biological Science
Study of living systems at the molecular level, structure of
genes and chromosomes, regulation of gene expression at the level
of DNA, RNA and protein synthesis, signal transduction pathways
and gene regulation, the cell cycle, abnormal regulatory processes
318 - 502 Molecular Biology for Engineers and Computer Scientists
This course is designed for who lack the biological
prerequisites, essential aspects of cell biology and molecular
biology, macromolecules and organization of the cell, cell cycle and
signal transduction, DNA structure and organization, the genetic
code, and gene expression and its regulation, polymerase chain
reaction and genome sequencing
Credit
36(0-108-0)
Credit
2(2-0-4)
2(2-0-4)
318 - 503
Bioinformatics 1
DNA sequence analysis, multiple sequence alignment,
phylogenetic tree construction, computational genomics, gene
expression and protein structure analyses
318 - 504 Bioinformatics 2
Algorithmic and probabilistic methods for analysis of DNA and
protein, data mining analysis, write computer programs for data
analysis
318 - 671 Seminar in Molecular Biology and Bioinformatics 1
Analysis of the literature from current literature in molecular
biology, presentation and interpretation of research findings,
understand the code of conduct for researchers
318 - 672 Seminar in Molecular Biology and Bioinformatics 2
Seminar in advanced topics in molecular biology and
bioinformatics, emphasize the rationale for research projects and the
presentation and interpretation of research findings
Elective Courses
318 - 505 Yeast Genetic Engineering
Genetic engineering of yeast Saccharomyces cerevisiae and
other speices, yeast as a heterogeneous host for production of
recombinant protein, yeast as a model organism for functional
Genomics studies
318 - 506 Plant Genetic Engineering
The scientific and technical advances which underlie the
production of genetically modified crops, plant genome organization
and gene expression, plant tissue culture and genetic
transformation, genetic manipulation to confer the improvement of
crop yield and quality
318 - 507 Intellectual Properties
Surveys intellectual property laws, including patents,
copyrights, trademarks, design protection, how to apply for a patent,
look for technology that is available for licensing
2(1-2-3)
2(1-2-3)
1(0-2-1)
1(0-2-1)
Credit
2(2-0-4)
2(2-0-4)
1(1-0-2)
318 - 508
318 - 509
318 - 673
318 - 674
318 - 681
318 - 682
319 - 501
319 - 502
319 - 503
Functional Genomics
Acquisition of DNA expression data, identify high-yield
candidate genes/ ESTs for further biological investigation, the basics
of the various bioinformatics methodologies available to analyze
RNA expression data sets
Metabolic Network Reconstruction
To reconstruct a metabolic network. The interplay between the
many different intracellular reactions, how the fluxes through the
different pathways are regulated. Analysis of the interaction between
different cellular reactions
Seminar in Molecular Biology and Bioinformatics 3
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Seminar in Molecular Biology and Bioinformatics 4
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Special Topics in Molecular Biology and Bioinformatics 1
Independent study on interesting issues in progress or new
findings in molecular biology and bioinformatics
Special Topics in Molecular Biology and Bioinformatics 2
Independent study on interesting issues in progress or new
findings in molecular biology and bioinformatics
Techniques in Genomics and Proteomics
Current and emerging technologies and approaches for
genome sequencing, analyzing protein structure and function,
protein:protein interactions and microarrays
Computer in Molecular Biology
New technologies and tools for understand the major issues
concerning representation and analysis of genomes, sequences and
proteins
Science Communication
To make scientific activity more understandable
2(2-0-4)
2(2-0-4)
1(0-2-1)
1(0-2-1)
1(1-0-2)
1(1-0-2)
2(1-3-2)
2(1-2-3)
2(1-2-3)
322 -552
344 -563
344-564
344-571
344-572
Combinatorial Design
Selected topics from design theory, latin squares, finite
geometries, finite fields, error correcting codes, other related topics
Database Management System
Database system architecture, Relational database and
normalization process, Database models and database design,
Relational database languages : relational algebra and relational
calculus languages, Database security and integrity,
Transactions and concurrency control
Information Retrieval
Information retrieval models, retrieval evaluation, query
language and operations, text and multimedia operations, indexed
and searching, parallel and distributed information retrieval, libraries
and bibliographical systems, digital libraries
Artificial Intelligence
Concepts and theories of intelligent systems, searching
techniques, Heuristic search, propositional logic, Predicate logic,
production systems, logic reasoning systems, deductive and
inductive inference systems,
uncertainty,
knowledge
representation such as frame, conceptual graph, recursive transition
network, introduction to Prolog programming, Overview on expert
system, machine learning, neural network, robotics, computer vision
and natural language processing
Expert Systems
Knowledge acquisition, interviewing for content and
classification, conceptualizing the domain expert, rule-based
reasoning, logics and automated reasoning, inferencing,
knowledge representation, explanations, uncertainty management,
probabilistic uncertainty, belief theory and fuzzy set theory, expert
system life cycle, building expert system using expert system shells,
validation and integration
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(3-0-6)
344-573
344-662
346-521
346-531
346-532
Neural Networks
Biological neural networks, brain central and modulation
systems, pattern recognition, pattern classification, neural network
modeling, artificial neural network, unsupervised learning,
matching and self-organized networks, supervised learning, back
propagation neural network, adaptive resonance theory, neural
networks based on competition, Fuzzy reasoning, applications of
neural networks algorithms and learning models
Data Warehouse and Data Mining
Architecture and infrastructures of data warehouse, design and
implementation of data warehouses, techniques in data mining,
knowledge representations, use of data mining software
Analysis of Advanced Statistical Models
Definition of a statistical model, generalized linear models,
likelihood function and parameter estimation, models for continuous
data, model for binomial data, model for Poisson data, models for
negative binomial data, models for zero-inflated Poisson data,
computer software applications
Applied Multivariate Analysis
Aspects of multivariate analysis, the multivariate normal
distribution, comparisons of several multivariate means, multivariate
regression, discrimination and classification, path analysis, cluster
analysis, principal component analysis, factor analysis, canonical
correlation analysis, computer software applications
Experimental Designs
Introduction; design and analysis of single-factor experiments,
single-factor experiments having repeated measures on the same
elements, design and analysis of factorial experiments, factorial
experiments in which some of the interactions are confounded, Latin
Squares and related designs, analysis of covariance, repeated
measurement, computer software applications
3(3-0-6)
3(3-0-6)
3(2-2-5)
3(2-2-5)
3(2-2-5)
346-534
346-542
326 - 512
326 - 641
326 - 681
330 - 601
347-531
Statistical Decision Theory
Review of probability, basic concepts of decision analysis,
elementary decision problems, continuous-variable decision
problems, sufficient statistics and conjugate distributions,
multivariate normal process, sequential decision problems
Simulation Techniques
Introduction to simulation, concepts in discrete-event, random
number generator, random events, monte-carlo simulation,
simulation examples, verification and validation of simulation, output
analysis, comparison and evaluation of alternative system, computer
software applications
Microbial Physiology
Structures and functions of microbial cells, microbial growth,
microbial control, transportation of substances, energy production of
heterotrophs and autotrophs, metabolism of carbohydrate, lipid,
nitrogen and control of metabolisms
Advanced Bacteriology
Presentation and group discussion of current knowledge from
published articles on bacteriology
Advanced Virology
Presentation and group discussion of current knowledge from
published articles on virology
Cells and Plant Cell Biology
Ultrastructure of cell and organelles, cell physiology, cell
differentiation and cell specialization in plant, methods for
cytological and cytochemical analysis and plant tissue culture
Biological Statistics and Research Methodology
Aspects of multivariate analysis, the multivariate normal
distribution, comparisons of several multivariate means, multivariate
regression, discrimination and classification, path analysis, cluster
analysis, principal component analysis, factor analysis, canonical
3(3-0-6)
3(2-2-5)
3(2-3-4)
3(3-0-6)
3(3-0-6)
4(3-3-6)
4(3-2-7)
347-532
318 – 505
318 – 507
318 – 508
318 – 509
318 – 510
correlation analysis, computer software applications
Applied Statistics for Research
Introduction; design and analysis of single-factor experiments,
single-factor experiments having repeated measures on the same
elements, design and analysis of factorial experiments, factorial
experiments in which some of the interactions are confounded, Latin
Squares and related designs, analysis of covariance, repeated
measurement, computer software applications
Yeast Genetic Engineering
Genetic engineering of yeast Saccharomyces cerevisiae and
other speices, yeast as a heterogeneous host for production of
recombinant protein, yeast as a model organism for functional
Genomics studies
Intellectual Properties
Surveys intellectual property laws, including patents,
copyrights, trademarks, design protection, how to apply for a patent,
look for technology that is available for licensing
Functional Genomics
Acquisition of DNA expression data, identify high-yield
candidate genes/ ESTs for further biological investigation, the basics
of the various bioinformatics methodologies available to analyze
RNA expression data sets
Metabolic Network Reconstruction
To reconstruct a metabolic network. The interplay between the
many different intracellular reactions, how the fluxes through the
different pathways are regulated. Analysis of the interaction between
different cellular reactions
Protein Technology and Engineering
Study on interaction among chemical structure of proteins,
physical structure of proteins, properties of enzymes, kinetics of
enzymes, biochemical techniques of protein purification, modeling of
3(3-0-6)
2(2-0-4)
1(1-0-2)
2(2-0-4)
2(2-0-4)
2(2-0-4)
318 - 511
318 – 673
318 – 674
322 - 552
344 - 563
344 - 564
344 - 571
protein structure and its modification by genetic engineering and
protein structure analysis
Genetic Engineering
Definition and application of genetic engineering, structure and
function of DNA, flow of genetic information, recombinant DNA
technology, cloning, site directed mutagenesis, sequencing, gene
expression, the impacts of genetic engineering in medicine,
environmental science and agriculture, biosafety control
Seminar in Molecular Biology and Bioinformatics 3
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Seminar in Molecular Biology and Bioinformatics 4
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Combinatorial Design
Selected topics from design theory, latin squares, finite
geometries, finite fields, error correcting codes, other related topics
Database Management System
Database system architecture, Relational database and
normalization process, Database models and database design,
Relational database languages : relational algebra and relational
calculus languages, Database security and integrity, Transactions
and concurrency control
Information Retrieval
Information retrieval models, Retrieval evaluation, Query
language and operations, Text and multimedia operations, Indexed
and searching, Parallel and distributed information retrieval,
Libraries and bibliographical systems, Digital libraries
Artificial Intelligence
Concepts and theories of intelligent systems, Searching
techniques, Heuristic search, Propositional logic, Predicate logic,
2(2-3-4)
1(0-2-1)
1(0-2-1)
3(3-0-6)
3(3-0-6)
3(3-0-6)
(2-2-5)
344 - 572
344 - 573
344 - 662
346 - 521
Production systems, Logic reasoning systems, Deductive and
inductive inference systems, Uncertainty, Knowledge representation
such as frame, conceptual graph, recursive transition network,
Introduction to Prolog programming, Overview on expert system,
machine learning, neural network, robotics, computer vision and
natural language processing
Expert Systems
Knowledge acquisition, Interviewing for content and
classification, Conceptualizing the domain expert, Rule-based
reasoning, Logics and automated reasoning, Inferencing,
Knowledge representation, Explanations, Uncertainty management,
Probabilistic Uncertainty, Belief theory and fuzzy set theory, Expert
system life cycle, Building expert system using expert system shells,
Validation and integration
Neural Networks
Biological neural networks, Brain central and modulation
systems, Pattern recognition, Pattern classification, Neural network
modeling, Artificial neural network, Unsupervised learning,
Matching and self-organized networks, Supervised learning, Back
propagation neural network, Adaptive resonance theory, Neural
networks based on competition, Fuzzy reasoning, Applications of
neural networks algorithms and learning models
Data Warehouse and Data Mining
Architecture and infrastructures of data warehouse, Design and
implementation of data warehouses, Techniques in data mining,
Knowledge representations, Use of data mining software
Analysis of Advanced Statistical Models
Definition of a statistical model, generalized linear models,
likelihood function and parameter estimation, models for continuous
data, model for binomial data, model for Poisson data, models for
negative binomial data, models for zero-inflated Poisson data,
3(3-0-6)
3(3-0-6)
3(3-0-6)
3(2-2-5)
318 – 675
318 – 676
318 – 677
318 – 678
318 - 681
318 – 682
319 – 502
319 - 503
319-504
computer software applications
Seminar in Molecular Biology and Bioinformatics 5
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Seminar in Molecular Biology and Bioinformatics 6
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Seminar in Molecular Biology and Bioinformatics 7
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Seminar in Molecular Biology and Bioinformatics 8
Discussion of up-to-date research and development findings
with guest speakers and visiting scientists
Special Topics in Molecular Biology and Bioinformatics 1
Independent study on interesting issues in progress or new
findings in molecular biology and bioinformatics
Special Topics in Molecular Biology and Bioinformatics 2
Independent study on interesting issues in progress or new
findings in molecular biology and bioinformatics
Computer in Molecular Biology
New technologies and tools for understand the major issues
concerning representation and analysis of genomes, sequences and
proteins
Science Communication
To make scientific activity more understandable
Biosafety
Introduces the safety and quality control issues related to
product development in the biotechnology industry, issues related to
government regulations, Cartagena protocol on biosafety, the basics
of risk assessment, safety, storage and disposal of hazardous
materials, the information pertains to a laboratory for Biosafety Level
1-4 (BSL1-4) facilities, Biosafety guidelines
1(0-2-1)
1(0-2-1)
1(0-2-1)
1(0-2-1)
1(1-0-2)
1(1-0-2)
2(1-2-3)
2(1-2-3)
1(1-0-2)
346 - 531
346-532
346 - 534
346 - 542
347-531
347-532
Applied Multivariate Analysis
Aspects of multivariate analysis, the multivariate normal
distribution, comparisons of several multivariate means, multivariate
regression, discrimination and classification, path analysis, cluster
analysis, principal component analysis, factor analysis, canonical
correlation analysis, computer software applications
Experimental Designs
Introduction; design and analysis of single-factor experiments,
single-factor experiments having repeated measures on the same
elements, design and analysis of factorial experiments, factorial
experiments in which some of the interactions are confounded, Latin
Squares and related designs, analysis of covariance, repeated
measurement, computer software applications
Statistical Decision Theory
Review of probability, basic concepts of decision analysis,
elementary decision problems, continuous-variable decision
problems, sufficient statistics and conjugate distributions,
multivariate normal process, sequential decision problems
Simulation Techniques
Introduction to simulation, concepts in discrete-event, random
number generator, random events, monte-carlo simulation,
simulation examples, verification and validation of simulation, output
analysis, comparison and evaluation of alternative system, computer
software applications
Biological Statistics and Research Methodology
Aspects of multivariate analysis, the multivariate normal
distribution, comparisons of several multivariate means, multivariate
regression, discrimination and classification, path analysis, cluster
analysis, principal component analysis, factor analysis, canonical
correlation analysis, computer software applications
Applied Statistics for Research
3(2-2-5)
3(2-2-5)
3(3-0-6)
3(2-2-5)
4(3-2-7)
3(3-0-6)
326 - 651
364 - 511
373-570
660-711
660-713
660-791
Introduction; design and analysis of single-factor experiments,
single-factor experiments having repeated measures on the same
elements, design and analysis of factorial experiments, factorial
experiments in which some of the interactions are confounded, Latin
Squares and related designs, analysis of covariance, repeated
measurement, computer software applications
Advanced Immunology
Presentation and group discussion of current knowledge
from published articles on immunology
Human Genetics
Basic knowledge in human genetics and common genetic
disorders, technique of history taking, interviewing patients and their
families and the construction of genetic pedigree, studies on
population genetics, cytogenetics, molecular genetics, biochemical
genetics, immunogenetics, genetics of cancer, and other genetic
applications
Biomedical Laboratory Techniques
Theory, principle and laboratory techniques used in biomedical
science research, research ethics, basic techniques in biochemistry,
pharmacology, molecular biology, immunology and cell culture
Philosophy and Methodology of Dental Research
Definition and types of research, how to acquire knowledge,
reliability of bioinformatics, analysis of problems, research desing,
ethics, and how to read and criticize paper
Advanced Oral Science
Molecular biology of craniofacial development, cleft lip and
palate, current concepts of tooth eruption, molecular mechanisms of
oral cancer, wound healing, tissue engineering, basic science of the
prevention of dental caries and periodontal diseases, application of
molecular biology in dental research
Animal Cell Culture in Medical Research
3(3-0-6)
2(2-0-4)
2(0-4-2)
2(2-0-4)
3(3-0-6)
2(1-3-2)
Study of theory and laboratory technique in cell and tissue
culture, particularly mammalian cells for experimental research such
as toxicity test for dental materials, mitogenic factors, and cell
communication
Thesis
326-691
Thesis
Research work in microbiology under supervision of a thesis
advisor
Credit
24(0-72-0)