Supplemental Table 1. Characteristics of amputation and limb salvage surgeries of the studies included in the meta-analysis
1st Author
(publication year)
Mavrogenis
(2012)[8]
Location of
Tumor
Distal tibia
Amputation Level
Below-knee
Limb- Salvage Procedure
Allograft reconstruction
Postoperative Complications
Limb-salvage: delayed union,
allograft fracture, nonunion,
infection
Secondary
Amputation After
Limb Salvage
Evaluation of Function
and Quality of Life
13.0%
Every 6 weeks for the
first 6 months, every 6
months for the first 3
years, and then annually
Amputation: wound dehiscence
Bekkering
(2010)[20]
Around the knee
NA
joint
Allograft reconstruction or
prosthesis
NA
NA
NA
Robert (2010)[22]
Transfemoral,
below-knee
Femur, tibia,
amputation, hip
humerus, fibula,
disarticulation,
patella, pelvis
hemipelvectomy,
rotationplasty
Bone graft (autograft or
allograft), endoprosthetic
implant, composite
endoprosthetic allograft
NA
21.2%
Two weeks after
treatment
NA
Survived disease-free
state for 5 years or
longer after the end of
treatment and aged 25
years or above
Yonemoto
(2007)[23]
Femur, tibia,
humerus, ilium, NA
fibula, radius
NA
NA
Renard (2000)[21]
Limb-salvage: peroneal palsy,
wound margin necrosis, deep
infection, superficial infection,
pulmonary embolism,
pseudarthrosis, recurrent
dislocation, aseptic
Hemipelvectomy,
Enneking type III resection, endoprosthetic loosening, septic
hip disarticulation,
en bloc resection, curettage, loosening, prosthetic stem
above-knee or
cryosurgery, autogenous or fracture, sustained fracture,
Lower extremity
7.7%
below-knee
allogenic bone, prosthesis, limb-length inequality, femoral
amputation, knee
endoprosthesis
head replacement
disarticulation
At the end of 1997
Amputation: wound margin
necrosis, osteomyelitis
Davis (1999)[19]
Lower extremity
NA, not available.
Above-knee or
below-knee
NA
Limb-salvage: wound
complication
NA
NA