Research Infrastructure Grant Final Report
Due: 3 months after the end date
Please complete this form in 10pt Verdana font.
Section A – Project Identification
A.1
Project Information
Grant ID No.
Project Title
Funding Commenced
Funding End Date
A.2
Chief Investigator Information
Full Name
Contact Number
Email Address
A.3
Administering Institution
A.4
Research Institutions involved in this grant
(insert additional rows as needed)
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Section B – Funded Infrastructure
B.1
Please provide a brief lay summary of the infrastructure that was funded
(including any cash or in-kind contributions pledged in the application), including a
general description of what it is/will be used for and its significance to and potential
benefits for cancer research, with special reference to the translation of research findings
to clinical practice and improvements in cancer outcomes (see Appendix 1):
Please also mark with an X, which infrastructure categories best describe the skillset of
the personnel or the equipment the personnel support (approx 500 words).
Microscopy
Mass Spectrometry
Biobanking
High Throughput Sequencing
Animal facilities/animal imaging
Bioinformatics
Other
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
B.2
FTE supported by this Grant
Please provide a summary of the FTE staff employed through this grant.
Researchers
(include
post-docs,
research
fellows, snr
scientists)
Clinicians
/Clinical
Fellows
Research
support
staff
(include
RAs,
project
officers,
Technical
staff)
Nurse/data
managers
Program/
Research
Managers
Other
FTE
employed
through
grant
B.3
Provide details of all personnel supported by this grant (Please copy and repeat
this table for each person supported by this grant.):
Position Title
Name
Starting date
dd/mm/yy
End date (if applicable)
FTE on this grant
Key responsibilities (approx 25 words):
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Section C – Use & Governance
C.1 Provide details of all the research groups that have used this infrastructure over the
reporting period.
Research Group
Name
Group Leader Name
Use of
Infrastructure
(approx. no. of days
per month)
Are the group
external to
facility/institution in
which Infrastructure
is located? (yes/no)
C.2
Please list all research studies or projects that have used this infrastructure:
C.3
Governance/Access
Please confirm governance and access plans are in place that support collaborative use of
this infrastructure and describe which formal documentation/policies exist to support
governance and access (approx 250 words):.
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Section D – Research Outputs
Please include references for all publications or conference presentations (only those directly
related to the funded program) delivered during the reporting period that were made possible
through the funded infrastructure:
D.1
Journal articles
Please include references for all publications directly arising from the Grant. Include the
full reference (including authors and date of publication).
(Insert additional rows as necessary).
Type (Published or In
Press/Accepted)
D.2
Full Reference
Year of
Publication
Research Dissemination
Please include references for all abstracts/presentations given by funded personnel during the
course of the Grant to disseminate research findings or promote use of the infrastructure.
(Insert additional rows as necessary).
Type (Poster/
Oral/Keynote)
D.3
Full Reference
Location
(Local/
National/
International)
Year
Collaborations
Have any collaborations been initiated/strengthened primarily as a result of this grant?
Name
Institution
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Location
(Local, National,
International)
Due date 5pm, 31/03/2015
Section E Research Achievements
Please describe in lay terms, up to three of your most significant research achievements that
have occurred as a result of this grant. These achievements should be written in language
suitable for the general public and should outline what the problem was, what the
research/grant achieved and why this is important.
Please note that this information may be made available to the general public on the Cancer
Institute NSW website or any other materials for promotional purposes.
Please provide up to three major achievements – copy and paste the table below for each
additional achievement (please mark most appropriate impact category with an X).
Description of Achievement (approx 500 words)
Please choose one category that best describes this achievement:
Increased the capacity to do further research
Produced new knowledge
Developed new diagnostic tools or new therapies
Informed policy or practice
Improved health outcomes
Other - please describe:
Who will this achievement most directly impact?
Patients/Families
Clinicians
Public/Communities
Other Researchers
Other - please describe:
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Due date 5pm, 31/03/2015
E.2
Provide details of all personnel supported by this grant and their key achievements
made possible by this grant (Please copy and repeat this table for each person supported by
this grant.):
Position Title
Name
Starting date
dd/mm/yy
End date (if applicable)
FTE on this grant
Key responsibilities (approx 25 words):
Major achievements (approx 25 words):
Cancer Institute NSW – Research Infrastructure Grant
Final Report
E14/57740
Due date 5pm, 31/03/2015
Section F – Other Funding
F.1
Please list any funding awarded since the commencement of the grant where the funded infrastructure assisted in some way in
gaining the funding. Insert rows as needed.
Grant Type
Grant
Amount
% of funds
allocated to you
Years
Covered
by Grant
(e.g
20142016)
Cancer Institute NSW – Research Infrastructure Grant Final Report
E14/57740
Funding
Source
Grant Title
Chief
Investigators
Extent to which CINSW
grant assisted in
gaining this funding
(please rate from 0-10
10=CINSW grant
essential, 0=would
have occurred without
CINSW grant)
Due date 5pm, 31/03/2015
G. Certification
G.1
Certification by Chief Investigator
I certify that this is an accurate progress report for the period covered
Name
G.2
Date
Certification by Head of Department/Unit
I certify that this is an accurate progress report for the period covered
Name
G.3
Date
Certification by the Administering Institution
I certify that this is an accurate progress report for the period covered
Name
Date
Submission
● Please ensure that progress report has been certified by all parties.
● The Administering Institution is responsible for the accurate submission of completed
progress report form.
● Please note signatures are not required.
●
Please save your progress report using the following format for naming and in the email
subject line:
Grant ID #_2014ProgressReport_Surname
(e.g. 02RIG108_2014ProgressReport_Smith).
●
Email progress report to grants@cancerinstitute.org.au
● Please note, late submissions of progress reports may affect eligibility for future funding.
Cancer Institute NSW – Research Infrastructure Grant Final
Report
E14/57740
Due date 5pm, 31/03/2015
APPENDIX 1: CANCER INSTITUTE NSW MODEL OF TRANSLATION
Figure 1 below is the model of translational research used by the Cancer Institute NSW. This
model focuses on the translation of basic research into clinical research as well as being
applicable to the translation of population health and health services research informing
programs and service delivery.
Figure 1 outlines /classifies the stages of translational research as:

T1- developing treatments and interventions.

T2 - testing the efficacy and effectiveness of these treatments and interventions.

T3 - dissemination and implementation research for system-wide change.
Figure 1: Model of Translational Research
Westfall et al., (2007). Practice-based research – “blue highways” on NIH roadmap. JAMA,
297(4): 403-406 (adaptation)
NSW Health and Medical Research Strategic Review 2012—page 4 (adaption)
Cancer Institute NSW – Research Infrastructure Grant Final
Report
E14/57740
Due date 5pm, 31/03/2015
Detailed Translational Pipeline Definitions:
i.
ii.
iii.
T1 - Translation to Humans

Developing treatments and interventions

The translation of basic research into research with humans. Basic research
could cover a range of disciplines including: laboratory research,
epidemiology, psychometrics, social science.

The interface between basic research and the clinical setting, striving to find
how new knowledge of disease mechanisms can be developed into clinically
relevant understandings, and diagnostic and treatment regimes to be trialled
in humans.

Types of studies/activities – Observational studies, Case studies; Phase 1
and II clinical trials
T2 - Translation to Patients

Testing the efficacy and effectiveness of these treatments and interventions.

The translation of new clinical science and knowledge into routine clinical
practice and health decision making1. Translation of new clinically proven
knowledge of disease processes, diagnostic or treatment techniques into
routine clinical practice and health decision making.

Types of studies/activities - Phase III clinical trials; observational studies;
evidence synthesis and guidelines development.
T3 - Translation to Practice

Dissemination and implementation research for system-wide change2.

The application of information and insights derived from basic, clinical and
population health research to the provision of health services2.

Moving evidence-based guidelines into health practice, through delivery,
dissemination, and diffusion research.

Practice based research, where the evidence from clinical trials on carefully
selected patients is translated into guidelines for patients seen routinely in
practice.

Types of studies/activities - Dissemination research; implementation
research; diffusion research, Phase IV clinical trials.
1
Grimshaw et al, 2012
2
Wills NSW Health and Medical Research Strategic Review
Cancer Institute NSW – Research Infrastructure Grant Final
Report
E14/57740
Due date 5pm, 31/03/2015