Pharmacology Board Review Questions 102
102) Which of the following drugs is the standard to which all opiates (narcotics) are compared?
a) Codeine
b) Oxycodone
c) Hydrocodone
d) Meperidine
e) Morphine *
f) Fentanyl
103) Carbidopa, a drug used in the treatment of Parkinson’s disease, only works when combine with
levodopa.
*True
104) List 4 pharmacologic actions of aspirin.
a) Analgesic *
b) Anti-inflammatory *
c) Antipyretic *
d) Platelet inhibition *
105) Warfarin (Coumadin) and Dicumarol are classified as:
a) Antihypertensives
b) Anticoagulants *
c) Antiarrythmics
d) Antianginal
106) Which narcotic is Not used in dentistry?
a) Morphine *
b) Hydrocodone (component of Vicodin)
c) Oxycodone (component of Percocet)
d) Meperidine (Demerol)
e) Codeine
f) Fentanyl
107) the biological effects of glucocorticoids (cortisol and its natural and synthetic analogs) occur in
target cells following the interaction of the steroid with a specific glucocorticoid receptor.
*True
108) What are some adverse side effects of local anesthetics?
a) Toxicity *
b) Allergy *
109) When two drugs having similar effects are administered in combination, and the resulting response
is the sum of the individual actions of each drug when given alone, then this result is referred to as:
a) An additive effect *
b) A synergistic response
c) An antagonistic effect
d) Cumulative action
110) All of the following are classified as what type of drug? *Antiepileptic drugs or anticonvulsants
a) Gabapentin (Neurontin)
b) Carbamazepine (Tegretol)
c) Phenytoin (Dilantin)
d) Diazepam (Valium)
e) Valproic (Depakene)
111) Oral contraceptives block ovulation by inhibiting which anterior pituitary hormones below?
a) Follicle stimulating hormone (FSH) *
b)Growth hormone (GH)
c) Thyroid stimulating hormone (TSH)
d) Luteinizing hormone (LH) *
e) Adrenocorticotrophic hormone (ACTH)
112) For a patient who is taking anticoagulants, what is the most valuable test used in evaluating the
patient as a surgical risk?
a) PTT (Partial Thromboplastin Time)
b) PT (Prothrombin Time) *
c) Platelet count
113) For a patient who is taking anticoagulants, what is the most valuable test used in evaluating the
patient as a surgical risk?
a) PTT (Partial Thromboplastin Time)
b) PT (Prothrombin Time)*
c) Platelet count
114) What steroid hormone produced by the adrenal cortex regulates sodium and potassium balance in
the blood?
a) Vasopressin
b) Aldosterone *
c) Epinephrine
d) Norepinephrine
115) Which of the following drugs reduce GI motility and are used to treat diarrhea?
a) Loperamide (modium) *
b) Lorazepam (Ativan)
c) Diphenoxylate and atropine (Lomotil) *
d) Propranolol (Inderal)
116) Your patient is taking the medications listed below. She complains of dry mouth. Each of the
medications probably contributes EXCEPT one. Which one is the EXCEPTION?
a) Alendronate (Fosamax) *
b) Nortriptyline (Pamelor)
c) Escitalopram (Lexapro)
d) Diphenhydramine (Benadryl)
117) All of the following drugs are used to treat what condition?
a) Dexmethylphenidate (Focalin)
b) Extended-release methylphenidate (Concerta)
c) Mixed amphetamine salts (Adderall
d) Atemoxetine (Strattera)
e) Controlled-delivery methylphenidate (Metadate CR)
* Attention deficit hyperactivity disorder (ADHD)
118) All of the following drugs have an action which results in increased effects of acetylcholine within
the autonomic nervous system and at the neuromuscular junctions.
a) Neostigmine
b) Physostigmine
c) Edrophonium
d) Pyridostigmine
*True
119) Which of the following describes cholinergic nerve fibers within the autonomic nervous system?
a) Nerve fibers whose nerve endings in effector organs release norepinephrine or epinephrine upon
stimulation *
b) Nerve fibers whose nerve endings in effector organs release acetycholine upon stimulation
120) Which of the following drugs is a synthetic opioid analgesic used as intravenous sedative and is
more potent than morphine?
a) Meperidine (Demerol)
b) Pentazocine (Talwin)
c) Propoxyphene (Darvon)
d) Fentanyl *
121) Drugs travel through the blood stream by binding to albumin plasma protein. However, only a
small number of drugs travel through the blood stream by this mechanism.
a) The first statement is true; the second statement is false *
b) The first statement is false; the second statement is true
c) Both statements are true
d) Both statements are false
122) Which of the following drugs may be used in controlling salivary secretions to help in obtaining a
dry field?
a) Atropine sulfate
b) Glycopyrrolate (Robinul
c) Belladonna derivatives
d) Propantheline bromide (Pro-banthine)
e) All of the above *
123) Which drug action would be most useful to induce salivation?
a) Cholinergic *
b) Anticholinergic
124) Opioid drugs (narcotics) are used as which of the following?
a) Analgesics *
b) Anti-inflammatories
c) Antitussives *
d) Antidiarrheals *
e) Preanesthetic medications *
125) All of the following drugs are classified as what type?
a) Hydrocortisone
b) Methylprednisolone
c) Prednisone
d) Triamcinolone
e) Dexamethasone
* Corticosteroids
126) Implicit in the interaction of a drug with its physiological receptor is that drug does not create
effects, but rather, modulates intrinsic physiological cell functions.
*True
127) Implicit in the interaction of a drug with its physiological receptor is that drug does not create
effects, but rather, modulates intrinsic physiological cell functions.
*True
128) Severe allergic reactions, such as anaphylaxis and angioedema of the glottis, commonly require
immediate therapy with which of the following drugs?
a) Histamine
b) Dopamine
c) Epinephrine *
d) Heparin
129) Which substance is an enzyme formed in the kidney and released into bloodstream where it has an
important role in the formation of angiotensin?
a) Plasmin
b) Lysozyme
c) Renin *
d) Heparin
130) Which drugs are Monoamine Oxidase (MAO) inhibitors?
a) Isocarboxazid (Marplan)
b) Tranylcypromine (Parnate)
c) Phenelzine (Nardil)
d) All of the above *
131) Which of the following drugs is a bronchodilator?
a) Epinephrine
b) Albuterol (Proventil)
c) Salmeterol (Serevent)
d) Metaproterenol (Alupent)
e) Aminophylline
f) All of the above *
132) Which of the following drugs are ACE inhibitors?
a) Benazepril (Lotensin)
b) Enalapril (Vasotec)
c) Lisinopril (Zestril)
d) Ramipril (Altace)
e) Fosinopril (Monopril)
f) Quinapril (Acupril)
g) Perindopril (Aceon)
h) All of the above *
133) Ester0type local anesthetics are metabolized where?
a) Liver
b) Lungs
c) Plasma *
d) Kidneys
134) Name the four stages of general anesthesia.
1. Amnesia / analgesia *
2. Delirium: begins with unconsciousness and ends with loss of eyelid reflex, purposeless movements
and hyper-reaction, dilated pupils, reflex vomiting, tachycardia, and hypertension *
3. Surgical: four planes *
4. Medullary paralysis: cessation of respiration, ending with death without proper treatment *
135) A patient was given penicillin 15 minutes ago and develops the following signs and symptons.
What kind of reaction is this patient having?
a) Laryngeal edema
b) Urticaria (welts that itch)
c) Severe hypotension
d) GI disturbances
e) Bronchoconstriction (airway constriction)
f) Shock
g) Anaphylactic reaction (anaphylactic shock) *
136) Growth hormone is also called:
a) Vasopressin
b) Aldosterone
c) Somatotropin *
d) Dopamine
137) Epinephrine,a vasoconstrictor, is included in dental local anesthetic preparation for the following
three reasons:
1. It prolongs the duration of anesthesia *
2. To provide a hemostasis such that local bleeding is controlled or reduced *
3. To delay the absorption of anesthetic into the systemic circulation thus reducing the chance of
systemic toxicities. *
138) All of the following drugs are considered to be in what drug class?
a) Glyburide (DiaBeta)
b) Metformin (Glucophage)
c) Pioglitazone (Actos)
d) Chlorpropamide (Diabinese)
e) Chlorpropamide (Diabinese)
f) Tolbutamide (Orinase)
g) Rosiglitazaone (Avandia)
h) Antidiabetic agents or oral hypoglycemic agents *
139) Which term is a compulsive, uncontrollable dependence on a substance, habit, or practice to such a
degree that cessation causes severe emotional, mental, or physiological reactions?
a) Habituation
b)Tolerance
c) Addiction *
d) None of the above
140) Benzodiazepines (Valium-type drugs) have which of the following modes of action:
a) Reversal of schizophrenia
b) Cause relaxation of the skeletal muscles *
c) Are analgesic in nature
d) Are useful in treating attention deficit hyperactivity disorder (ADHD)
141) Which of the following agents has little value in treating acute inflammation?
a) Ibuprofen
b) Acetaminophen *
c) Aspirin
d) Naproxen
142) Which of the following drugs is most effective in acting against syncope?
a) Epinephrine
b) Antihistamine
c) Aromatic spirits of ammonia *
d) Nitrous oxide
143) The brief duration of general anesthetic action of an ultra-short-acting barbiturate is due to what
factor?
a) Rapid rate of metabolism in the liver
b) Low lipid solubility, resulting in a minimal concentration in the brain
c) High degree of binding to plasma proteins
d) Rapid rate of redistribution from the brain to peripheral tissues *
e) Slow rate of excretion by the kidneys
144) All the following are considered to be what type of anesthetic?
a) Ether (diethyl ether)
b) Halothane
c) Enflurane
d) Isoflurane
e) Sevoflurane
f) Methoxyflurance
g) Deslurane
h) Inhalation anesthetics *
145) Diphenydramine (Benadryl), chlorpheniramine (Clor-Trimeton), loratidine (Claritin), and
desloratidine (Clarinex) are antihistamines at which histamine receptor site listed below?
a) H1 receptor site *
b) H2 receptor site
146) Which of the following are advantages of using nitrous oxide analgesia?
a) Rapid onset of action
b) Elevates pain threshold
c) Produces euphoria
d) Pleasant induction
e) Titratable
f) Rapid and complete recovery
g) Virtually no adverse effects in absence of hypoxia
h) Therapeutic for many medically compromised patients
i) Suitable for all ages
j) All of the above *
147) Your patient indicates the he experiences swelling and itching at the site of application when using
an over-thecounter local anesthetic called benzocaine and dibucaine. Is it likely that this patient will
also react to an infiltration of lidocaine?
a) Yes
b) No *
148) All of the following drugs are used to treat psychosis EXCEPT one. Which one is the EXCEPTION?
a) Chlorpromazine (Thorazine)
b) Thioridazine (Mellaril)
c) Risperidone (Risperdol)
d) Nitrous oxide *
e) Quetiapine (Seraquel)
f) Clozapine (Clozaril)
g) Olanzapine (Zyprexa)
h) Haloperidol (Haldol)
149) Ethyl alcohol causes a well-marked dieresis by inhibiting the production of which hormone?
a) Growth Hormone
b) Insulin
c) Antidiuretic Hormone (ADH) *
d) Epinephrine
150) Which of the following is the most likely complication seen with chemotherapy treatment?
a) Renal failure
b) Alopecia *
c) Peripheral neuropathy
d) Glaucoma