Three-dimensional echocardiographic evaluation of severe tricuspid regurgitation due to leaflet damage by permanent pacing lead Oswald J. Lee,1 Alex P.W. Lee,2 Micky W.T. Kwok,1 Song Wan 1* 1Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong; 2Division of Cardiology, Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong #Corresponding to: Song Wan, MD, FRCS, FACC Division of Cardiothoracic Surgery Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong Tel: 852-2632 2629 Fax: 852-2637 7974 E-mail: swan@cuhk.edu.hk A 76 year-old woman with recent history of permanent pacemaker insertion presented with congestive heart failure. Transthoracic echocardiography (TTE) showed mildly impaired left ventricular function, moderate functional mitral regurgitation, and severe tricuspid regurgitation. However, the mechanism of pacemaker lead causing severe regurgitation was not directly visualized on two-dimensional imaging (Figure A). Three-dimensional (3D) TTE revealed the pacemaker lead was “stuck” to the septal leaflet of tricuspid valve (arrow), raising the suspicion of pacing lead damage of the valve as the cause of severe regurgitation (Figure B). Mitral and tricuspid valves repair was performed. Preoperative 3D transesophageal echocardiography (Figure C) demonstrated clearly the pacemaker lead passed “through” the body of the tricuspid septal leaflet, hindering its excursion and causing organic regurgitation. Surgical inspection confirmed the perforation of the tricuspid septal leaflet by the pacemaker lead (Figure D). The lead was surgically freed from the valve and the leaflet repaired, followed by a ring annuloplasty. Postoperative echocardiography confirmed competent valve closure (Figure E). The patient recovered uneventfully. This case illustrated how 3D echocardiographic imaging was helpful to more clearly delineate the location of the pacemaker lead and its impact on the tricuspid valve. Disclosures: All authors have no conflict of interest. Figure legends Figure A: Preoperative two-dimensional transthoracic echocardiography (TTE) imaging. Figure B: Preoperative three-dimensional (3D) TTE imaging. Figure C: Preoperative 3D transesophageal echocardiography imaging. Figure D: Intra-operative surgical finding showed the pacemaker lead perforated the tricuspid septal leaflet. Figure E: Postoperative 3D transesophageal echocardiography imaging. Figure A Figure B Figure C Figure D Figure E