H1N1 SUMMARY OF H1N1 UNICEF INFLUENZA PANDEMIC ACTIVITIES TACRO Region Dr. Enrique Paz Health and Nutrtion Advisor UNICEF TACRO region I. 2009 influenza pandemic background: 1. Generalities of the influenza pandemic: In mid-March, 2009, the Mexican government reported an increase in the cases of respiratory illnesses, characterised by cases of influenza accompanied by severe pneumonia. Reporting of these cases began when cases of seasonal influenza were clearly decreasing. The number of cases continued to grow in the first weeks of April, when a new strain of influenza A was identified. Due to the emergence of the new strain of influenza and its propagation around the world, on 11 June, 2009, WHO declared a phase 6 pandemic. By 6 August, 2009, a total of 174,913 cases of influenza had been reported, including 1,411 deaths, in 166 countries and territories. One of the most affected groups was healthy young adults. The majority of cases presented light symptoms that included coughing, fever, sore throat, general discomfort and headache; gastrointestinal symptoms were also observed. The severe illness was characterised by pneumonia and respiratory insufficiency, while bacterial co-infection was infrequent. The risk factors for the severe illness were pregnancy, heart disease, diabetes, asthma, pulmonary emphysema, immunodeficiency and obesity. In August of 2009, WHO urged northern hemisphere countries to prepare for a second wave of the H1N1 influenza A pandemic. Countries with a tropical climate were to prepare for an increase in the number of cases. Countries of the temperate areas south of the hemisphere were to keep their surveillance systems active. The reality of the H1N1 A virus situation required accelerating the efforts to mitigate its effects on children and women. Concerned, diverse United Nations agencies issued a call to action to work together, with NGO and civil society partners, to support governments and communities in reducing the impact of the pandemic. 2. Epidemiology of the H1N1 influenza pandemic in Mexico, 2009: - The greatest number of cases occurred among children 1-19 years of age, with low mortality. The greatest mortality occurred in the 25-65 year-old age group, predominantly in the 45-49 age group. Increase in maternal mortality, women with influenza and pneumonia. Impact on the health system due to the increase in number of doctor’s visits. 3. Regional plan for pandemic vaccination: This plan was developed and distributed by the member states in May of 2009. The main objectives were: - To strengthen seasonal influenza vaccination in the region. To assist member states in their preparation for introduction of the vaccine against pandemic H1N1 influenza A. Considering that the available vaccine for pandemic influenza was limited, risk groups were prioritised for vaccination. In July of 2009, the Strategic Advisory Group of Experts in Immunisation (SAGE) recommended that countries should consider three objectives: - To protect essential health infrastructure (vaccinating health workers). To reduce morbidity and mortality (vaccinating individuals with chronic pathologies). To reduce transmission of the virus (vaccinating schoolchildren). The population groups whose vaccination was recommended were: - Health workers Pregnant women Population over six months of age carrying chronic diseases Healthy young adults 19-49 years of age Preschool and school students 5 -8 years of age Children between six months and four years of age Healthy adults over fifty years of age As in the case of any vaccine, surveillance of events supposedly attributed to vaccination or immunisation is essential. - Additional vaccination recommendations: - - - In order to reduce lost doses and ensure equitable access to influenza vaccine, the adjuvant vaccine should be used wherever possible. The industrialised countries of the Americas region with abundant vaccine are encouraged to contribute to supplying vaccine to those with less access. Recognising that Brazil and Mexico embarked on vaccine production, the TAG encourages PAHO to carry out regional strategic planning that ultimately leads to vaccine self-sufficiency. In order to ensure equitable access to the vaccine against pandemic influenza, countries should use the PAHO rotating fund to purchase vaccine. Due to the high morbidity and mortality caused by seasonal influenza, vaccination should not be suspended. During introduction of the vaccine, countries should constantly monitor: Events attributed to vaccination that are considered serious New events Rumours Events that take place in the groups of individuals Programme errors Countries should prepare social communication strategies aimed at: Maintaining public trust by informing in a clear and transparent way. Ensuring that individuals and their families use mitigation interventions for prevention. Ensuring that all of the population understand the recommendations and the reason for vaccinating priority groups. Understanding the general benefits and the risk of events associated with vaccination that may occur. 4. The role of UNICEF in the 2009 H1N1 influenza pandemic: During 2009, UNICEF instructed its regional and country offices to carry out some actions to mitigate the influenza pandemic: - Mobilisation of local-level resources that include needs related to the H1N1 A pandemic, allocating unused funds to immediate implementation of H1N1 activities. Country offices should foster/accelerate specific pandemic programmes, such as C4D for H1N1, WASH and health. They should identify upcoming local-level meetings at which to introduce and discuss H1N1, opportunities such as 15 October, world hand-washing day. Updating of knowledge regarding the pandemic. Fostering of inclusion of the H1N1 agenda in regular programmes. Fostering of review of programmes in key sectors that can be speeded up according to the potential impact of H1N1. Supporting and monitoring preparation of response to the pandemic at country level. The role of UNICEF TACRO: The role of TACRO in this process was in two areas: In-house: - - Creation of the TACRO pandemic working group to ensure sustainability, define roles and programmes in the response to the pandemic, and provide technical support and guides to the offices. Facilitation of access to and management of knowledge regarding all pertinent technical information, guides, documents and EIC material prepared. Email from Regional Advisor. Enrique Paz to CO: Guideliens of funding used to Country Offices: ( see email on Decembe 15, 2009 annex 1) External: - Interagency collaboration: participation in follow-up of meetings of the interagency communication working group and close cooperation with UNSIC, PAHO and WHO in the response to the pandemic. - The role of UNICEF in health - - Providing support to remote areas of risk (diagnostic methods available only in cities). Advocacy for acquisition of paediatric TAMIFLU and medicines. Carrying out personnel negotiations and effective coordination among levels and sectors to organise the response of health services under decentralisation of the service provision scheme. Support to families with regard to health and mental health. 5. Funding: UNICEF allocated funds to the influenza pandemic aimed at the specific activities defined above. In order to allocate funds to the regional offices, it was necessary to prioritise countries for action. UNSIC and WHO identified prioritisation criteria for United Nations support: - The 49 least developed countries (LDC) defined by the World Bank The 72 eligible GAVI countries UNICEF gave priority to the countries in which under-five mortality is high and in which the impact of the pandemic would be great. Adding both sets of countries and excluding those repeated in the two criteria, the total was 77 countries. To this end it was indicated that the regional offices should identify particularly vulnerable countries and inform New York of them. At world level, UNICEF will mobilise resources with the leaders of PARMO. The necessary funds will be provided by the United Nations System Influenza Coordination (UNSIC). II. Preparation for the 2010 influenza pandemic: In LAC, the 35 countries of the Americas reported confirmed cases of H1N1 influenza A and a significant number of deaths. Due to this, UNICEF allocated funds to TACRO to be used in specific activities according to three generalised scenarios of virus transmission. In addition, other enities, such as the US Department of Health and Human Services (through its Office of Emergency Preparedness), the Pan-American Health Organization and the Centers for Disease Control (CDC) executed training, sample analysis and preparedness programmes in the various countries of the region. Funding of 2009-2010 pandemic influenza needs: 1. Communication for Development interventions: Funding: 700,000.00 USD Priority countries: Panama, Bolivia, Barbados, Costa Rica, Chile, the Dominican Republic, Paraguay, Ecuador, Guatemala, Honduras, Nicaragua, El Salvador, Haiti, Belize, Jamaica and Peru. Orientation: UNICEF should focus on the execution and expansion of communication programmes aimed at facilitating the adoption and reinforcement of preventive behaviours and correct and veracious information for preparing for the second wave of H1N1 influenza A: - - Preparation for integrating behaviour change and social process change (C4D) in UNICEF programmes (WASH, education, health, nutrition and child protection). Increasing presentation to key individuals and target groups in order to apply prevention information and facilitate the adoption and reinforcement of key preventive behaviours. Provision of technical assistance to support COs in integrating preparation for H1N1 influenza and the pandemic in local communication campaigns, promoting a culture of hygiene and the prevention of risk. The proposal should be aimed towards good practices and lessons learned in the response to H1N1 (first wave) and previous events in which communication strategies that promoted behavioural change were applied, such as SARS and avian influenza. 2. Health: Funding: 400,000.00 USD Priority countries: Argentina, Guyana, Bolivia, Colombia, Guatemala, Honduras, Surinam, Ecuador, Nicaragua, Haiti and Peru. Orientation: The interventions should be aimed at reflecting the results of the technical meeting of the PAHO/WHO/UNICEF advisory group. Interagency coordination is aimed at supporting countries in identification of the epidemiological situation focussed on: - - Support with diagnostic methods in areas of risk. Advocacy for the existence of basic products at points of delivery (including paediatric TAMIFLU) and advocacy to promote equitable access in the distribution of vaccine. Support to primary and community care for children and at-risk pregnant women. Strengthening of negotiations with health personnel and coordination among the various levels of the system (central, state, federal, municipal, government) and among sectors in order to organise the response of health services under decentralisation of health care delivery aimed at excluded populations and at-risk populations. 3. Education: Funding: 240,000.00 USD Priority countries: Mexico, Venezuela, Nicaragua and Haiti. Orientation: These activities should be coordinated with C4D. - Planning for and response to the second wave of the pandemic in schools (parents, children, teachers and community) in order to promote and strengthen hygiene - behaviour messages and early detection of suspicious cases, linked with UNICEF work in WASH, nutrition and health. Preparation of a strategy for ensuring the continuation of learning, in the case of closed schools. The total funding sent was 1,340,000.00 USD, and this budget was spent by the countries according to the abovementioned guidelines as follows: Table 1: UNICEF TACRO H1N1 expansion funds, 2009-2010 Object of Assistance PBA Reference Expiry Date FLS Allotment Requisition Expenditure Unreq. Balance Req % Exp % Extra funds requested for 2010 Situation ARGENTINA GS/2009/0034 23/11/2010 35,000 0 0 35,000 61% 42% No information BELIZE GS/2009/0043 23/11/2010 45,000 0 0 45,000 100% 100% No information BOLIVIA GS/2009/0040 23/11/2010 80,000 59,039 45,015 20,961 100% 75% Vaccine rejection in the population CARIBBEAN REGIONAL Barbados and the Eastern Caribbean (for 10 islands ranging from Grenada to Turks and Caicos) GS/2009/0029 23/11/2010 45,000 0 0 45,000 98% 58% C4D and hygiene CARIBBEAN REGIONAL (Suriname) GS/2009/0030 23/11/2010 45,000 0 0 45,000 100% 46% C4D and cold chain CHILE GS/2009/0050 23/11/2010 45,000 45,000 44,997 - 100% 100% All spent/ earthquake COLOMBIA GS/2009/0051 23/11/2010 35,000 0 0 35,000 0% 0% COSTA RICA GS/2009/0055 23/11/2010 45,000 45,000 45,000 - 100% 100% Requested additional funding (ICON) 2010 ICON didn’t work Negotiation w/MOH Plan Developed C4D need children materials All spent Page 7 Object of Assistance PBA Reference Expiry Date FLS Allotment Requisition Expenditure Unreq. Balance Req % Exp % Extra funds requested for 2010 Situation DOMINICAN REPUBLIC GS/2009/0058 23/11/2010 45,000 0 0 45,000 91% 90% Funding will be disbursed by the end of July ECUADOR GS/2009/0059 23/11/2010 80,000 0 7,000 80,000 48% 18% EL SALVADOR GS/2009/0060 23/11/2010 45,000 0 0 45,000 33% 25% No information GUATEMALA GS/2009/0065 23/11/2010 80,000 0 0 80,000 100% GUYANA GS/2009/0042 23/11/2010 35,000 0 0 35,000 99% 99% October Health, child protection, emergencies HAITI GS/2009/0068 23/11/2010 130,000 0 0 130,000 15% 13% No information HONDURAS GS/2009/0069 23/11/2010 130,000 97,810 90,338 32,190 99% 99% JAMAICA GS/2009/0073 23/11/2010 45,000 0 0 45,000 0% MEXICO GS/2009/0084 23/11/2010 60,000 0 0 60,000 100% 99% Negotiation. School prevention NICARAGUA GS/2009/0087 23/11/2010 85,000 28,060 25,000 56,940 48% 48% Purchase of supplies/ reagents PANAMA GS/2009/0142 10/12/2010 45,000 0 0 45,000 0% 99% June-Sept. 80,000 raised 500,000 USD from other donors Negotiations w/MOH this month C4D, vaccines, training 0% No information 0% July-September will complete Page 8 Object of Assistance PBA Reference Expiry Date FLS Allotment Requisition Expenditure Unreq. Balance Req % Exp % Extra funds requested for 2010 Situation PARAGUAY GS/2009/0091 23/11/2010 45,000 1,106 1,106 43,894 45% PERU GS/2009/0092 23/11/2010 80,000 59,039 29,991 20,961 100% 89% C4D in Indian populations (Fabiola Quiroz) VENEZUELA GS/2009/0113 23/11/2010 60,000 0 0 60,000 100% 90% Negotiation. Hand washing and disease prevention 1,340,000 335,054 288,447 1,004,946 25% 22% Subtotal for TACRO 44% Cold chain and C4D materials Page 9 Appendix 1. Letter to Health and Communication officers from Enrique Paz, FA1 Advisor Health, Nutrition and WASH on December 15, 2009 Dear network colleagues Following RD's email to our Representatives, I am sending to you as information tools the following attachments that should help you address the H1N1 response. Nick Allipui email for Funds allocation. Health section power point including C4D, Emergency response and partnerships in H1N1 etc Program guidance issued from HQ NY, please share with other sections, in nutrition, education , C4D, WASH etc H1N1 Desk Review C4D H1N1 Guidelines Pan flu Communication guidelines C4D position paper PAHO Technical Advisory Group recommendations (August 26 2009) on the use of influenza A(H1N1) vaccines for our region, which we, UNICEF, fully endorse Our region might have a pandemic of different characteristics and special attention should be given to health prevention messages; interventions in hygiene practices in schools, hospitals, and open population; WASH infrastructure; adequate and timely treatment in vulnerable populations, such as pregnant women, patients with underlying chronic conditions, children under 5, elderly citizens and young adults at risk. Most fatal cases arrive to emergency rooms in critical conditions therefore the need to support health systems and hospitals that have been overburden and use this funds to leverage addition resources to enhance the health systems. For the immunization efforts, one of the most delicate aspects from a communication perspective is that any messages to the general public should contribute to their understanding of the need to prioritize vaccination to high risk groups. Further, the issue of vaccine procurement, etc. must be looked at on a country by country basis. Please support PAHO in that capacity. I look forward to a successful year and to use this funds to position UNICEF response in Health with the MOH and partners and be ready to prevent any outbreak possible of a second wave of the pandemic and don’t hesitate to contact TACRO for support in the areas of technical assistance, strategic representation and quality assurance of H1N1. Please program your funds around these issues, for any help don't hesitate to contact me, Paulo, Jesus in the Health, Nutrition and WASH section, and Tamar and Ivan in the communication section or Gianluca and Claudio in the Emergency Preparedness and Response. I hope this helps and if you need to discuss any further or want more information please just let me know. Abrazos and merry Christmas and happy new year Enrique Documento prepared by Miriam Fuentes Navarrete and Arlene Calvo Page 10 Documento prepared by Miriam Fuentes Navarrete and Arlene Calvo Page 11