THE NORTHEAST SUB-DIVISION THE CHARLES LOUIS DAVIS, D.V.M. FOUNDATION for the international advancement of veterinary and comparative pathology July 17, 2012 21st YEAR OF THE DAY-SEMINARS OF THE NORTHEAST SUB-DIVISION (Started in October 1991, at Hoffmann-La Roche, Nutley, NJ.) Dear friends and colleagues, It is with my pleasure to invite you and your colleagues to attend the 2nd Day-Seminar of the Sub-Division this year, on Friday, August 17 on the topic of RENAL CARCINENESIS. It is generously hosted by Janssen R&D (J&J), Raritan, NJ. Below, please find the program, information for contacting Janssen R&D and the persons who may assist you, and transportation/driving directions/hotels. The individual annual membership is $100.00, To pay by credit card, please call the Foundation office (Cherry Maxwell) per information below, or you may bring a check to the meeting. We were asked to monitor if membership fees of attendees (individual, corporate or institutional) is paid. For driving time, please allow extra time for security check and getting to the site of the seminar. Please register early and car-pool. Your cooperation is appreciated. Thank you. A note: please address all matters related to mailing, contact information, address changes, dues, etc., directly to Dr. Thompson. He and his office (Cherry Maxwell) are handling this important administrative work (contacting me is an un-necessary detour). Thank you. The seminar information is co-promoted by the Society of Toxicologic Pathology, and many of you may get it from this organization, as well. Looking forward to an exciting Day-Seminar, drive safely and see you Friday, August 17. Zadok. _____________________________________________________ Zadok Ruben, D.V.M., Ph.D. Patoximed Consultants 412 Sandford Avenue Westfield, New Jersey 07090 Tel. [908] 233-9740; Fax [908] 233-5451 E mail: zruben@patoximed.com Website: www.patoximed.com ___________________________________ Dr. Samuel W. Thompson National Programs Director 6245 Formoor Lane Gurnee, Illinois 60031 Tel. [847] 367-4359; Fax [847] 247-1869 (Cherry Maxwell, Administrator) February 9, 2016 Page 1 DAY SEMINAR -- RENAL CARCINOGENESIS Sponsored by The Charles Louis Davis, DVM Foundation- Northeast Subdivision (Co-promoted by The Society of Toxicologic Pathology) DATE: 17 AUGUST 2012, FRIDAY, 8AM-4PM LOCATION: OMP AUDITORIUM, 1000 ROUTE 202 SOUTH, RARITAN, NJ 08869 8:00-8:30 8:30-8:45 REGISTRATION, BREAKFAST Introduction and General Remarks 8:45-9:30 Renal Lesions in Rodents Jerry Hardisty 9:30-10:15 Pathology of Human Renal Tumors Priti Lal 10:15-10:30 10:30-11:15 BREAK Translational Science of Human Renal Cell Carcinoma Kimryn Rathmell 11:15-12:00 Role of oxidative injury in renal carcinogenesis James Klaunig 12:00-1:00 1:00-1:45 LUNCH Mechanisms of Renal Carcinogenesis in Laboratory Rodents Gordon Hard 1:45-2:30 Relevance of Rodent Renal Tumors for Human Health Risk Assessment 2:30-2:45 2:45-3:50 BREAK Panel Discussion: mechanisms of renal carcinogenesis in rodents and humans, relevance of rodent renal tumors for human health risk assessment Concluding Remarks 3:50-4:00 Samuel Cohen Jerry Hardisty, Priti Lal, Kimryn Rathmell, James Klaunig, Gordon Hard, Samuel Cohen Registration: Please register by Monday, August 13. Contact Debra Birchett (dbirche@its.jnj.com; Phone: 908-927-7472) and include name, institution, telephone and e-address. There is no registration fee for Foundation members. To become a member contact Cherry Maxwell at the Foundation (thompson@cldavis.org; phone: 847-367-4359); you may pay by credit card (annual individual membership is $100.00). The registered participants will be provided continental breakfast, light snacks and coffee during the breaks, lunch, and handout materials. February 9, 2016 Page 2 SPEAKERS Jerry F. Hardisty, DVM, DACVP, FIATP Experimental Pathology Laboratories, Inc., P.O. Box 12766, Research Triangle Park, North Carolina 27709 Phone: 919732 2718, Fax: 919 998 9607 Email: jhardisty@epl-inc.com Priti Lal, MD, FACP Assistant Professor Department of Pathology and Laboratory Medicine 6 Founders Pavilion, 3400 Spruce Street Philadelphia, PA 19104 Phone: 215 662 6504, Fax: 215 349 5910 Email: priti.lal@uphs.upenn.edu W. Kimryn Rathmell, MD, PhD Associate Professor of Medicine and Genetics Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill 450 West Drive, CB 7295, Chapel Hill, NC 27599 Phone: 919 966 3522, Fax: 919 966 8212 Email: rathmell@med.unc.edu James E Klaunig, PhD, FATS Professor, Department of Environmental Health School of Public Health, Indiana University 1025 East 7th st, Bloomington, IN 47405 Phone: 812 856-3957 Email: jklauni@indiana.edu Gordon C Hard, BSc, BVSc, PhD, DSc, FRCPath, FRCVS, FAToxSci, DACVP Private Consultant 203 Paku Drive, Tairua, 3508, New Zealand Telephone: 64-(0)7-864-9203 (business and home), E-mail: gordonhard@msn.com Samuel M Cohen, MD, PhD Professor, Department of Pathology and Microbiology Havlik-Wall Professor of Oncology, University of Nebraska Medical Center 983135 Nebraska Medical Center, Omaha, NE 68198-3135 Phone: 402 559-6388, Fax: 402 559-8330 Email: scohen@unmc.edu February 9, 2016 Page 3 TRASPORTATION, DRIVING DIRECTIONS AND HOTEL INFORMATION Train Closest is Metro Park in Iselin, NJ (near Woodbridge Shopping Center on Rt 1) For Amtrak, Please visit http://www.amtrak.com or call 1-800-USA-RAIL (1-800-8727245) DRIVING DIRECTIONS Street Address (GPS address): 1000 Route 202 South, Raritan, NJ 08869 From Newark Airport (40 miles/approx. 50 minutes) Follow Route 78 West to Exit 29 (Route 287 South) Continue on Route 287 South to Exit 17 (Routes 202/206 South)*** Take Routes 202/206 South to the Somerville Circle/Overpass. (Stay in middle lane to take overpass instead of going thru circle.) Take Route 202 South 1/2 mile to the traffic light (First Ave) JJPS, LLC is Building #700, first driveway on the right JJPRD is Building # 920, second driveway on the right PCC Building #930 is below JJRPD…across from the softball field OMP is Building #1000, third driveway on the right From JFK Airport (55 miles/approx. 80 minutes) Follow general exit road (Route 678 North/Van Wyck Expressway) to Belt (Shore) Parkway West Continue on Belt (Shore) Parkway West to Exit 3 (Verrazano-Narrows Bridge/Route 278 West) Cross Verrazano-Narrows Bridge and continue on Route 278 West/Staten Island Expressway to Exit 9 (West Shore Expressway/Route 440 West) Stay on 440 West across the Outerbridge Crossing into New Jersey Route 440 West becomes Route 287 North Travel on Route 287 North to Exit 14B (Route 22 West) Take Route 22 West to Routes 202/206 South and to the Somerville Circle/Overpass. (Stay in middle lane to take overpass instead of going thru circle.) Take Route 202 South 1/2 mile to the traffic light (First Ave.) OMP is Building #1000, third driveway on the right From LaGuardia Airport (60 miles/approx. 85 minutes) Follow signs to Grand Central Parkway West/New York City/ Triborough Bridge (center lane) Cross Triborough Bridge, move to left lane, and take the Deegan Expressway/Route 87 North to George Washington Bridge/Route 95 West Cross George Washington Bridge and follow Route 95 West to the New Jersey Turnpike South Continue on the New Jersey Turnpike South to Exit 14 (Route 78 West) Travel on Route 78 West to Exit 29 (Route 287 South) Continue on Route 287 South to Exit 17 (Routes 202/206 South) Take Routes 202/206 South to the Somerville Circle/Overpass. (Stay in middle lane to take overpass instead of going thru circle.) Take Route 202 South 1/2 mile to the traffic light (First Ave.) OMP is Building #1000, third driveway on the right February 9, 2016 Page 4 From New York City (50 miles/approx. 60 minutes) Take the Lincoln Tunnel to the New Jersey Turnpike South, Exit 14 (Route 78 West) [Or, the Holland Tunnel to the New Jersey Turnpike Extension, Exit 14 (Route 78 West)] Follow Route 78 West to Exit 29 (Route 287 South) Continue on Route 287 South to Exit 17 (Routes 202/206 South) Take Routes 202/206 South to the Somerville Circle/Overpass. (Stay in middle lane to take overpass instead of going thru circle.) Take Route 202 South 1/2 mile to the traffic light OMP is Building #1000, third driveway on the right From Philadelphia (55 miles/approx. 90 minutes) Take I-95 North into New Jersey Follow Route 31 North to Route 202 North Continue on Route 202 through Flemington J&J PRD is approximately 10 miles north of Flemington Circle on left hand side of highway Make a Uturn at First Ave. light to get on Route 202 South. OMP is Building #1000, third driveway on the right From J&J World Headquarters, New Brunswick (10miles/approx. 25 minutes) Follow Hamilton St. West for three blocks and make a right at the third light onto Easton Ave. Follow light onto Easton Ave. for 4.4 miles to Rt. 287 North (entrance is on left) Stay on Rt. 287 for 3.6 miles to Exit 14B, Rt. 22 West (exit from left lane) Follow Rt. 22 for 2.6 miles to Rt. 202/206 South Take Routes 202/206 South to the Somerville Circle/Overpass. (Stay in middle lane to take overpass instead of going thru circle.) Take Route 202 South 1/2 mile to the traffic light (First Ave.) OMP is Building #1000, third driveway on the right Limo Service Class A Transportation, LLC PO Box 286 Milltown, NJ 08850 Phone: 800-688-5466 Fax: 732-246-5465 Email: reservations@classatransportation.com Web: www.classatransportation.com /732-246-4004 February 9, 2016 Page 5 NEAR BY HOTELS Holiday Inn Express 947 US 202 Branchburg, NJ 08876 (Cross Streets: near the intersection of US-202 and N. Branch Rid. Telephone: 1-908-252-1000 Toll Free: 1-877-786-9480 Offers shuttle service to Raritan Campus www.bridgewaterexpress.com Hyatt house Branchburg 3141 Route 22 East, Branchburg, New Jersey, USA 08876 Tel: +1 908 704 2191 Offers shuttle service to Raritan site http://branchburg.house.hyatt.com/hyatt/hotels/index.jsp?null Marriott Bridgewater Hotel 700 Commons Way Bridgewater, NJ 08807 Phone: 1-908-927-9300 Toll free: 1-888-887-7869 Offers shuttle service to Raritan site www.marriott.com/hotels/travel/sosbw-bridgewater-marriott Summerfield Suites by Wyndham - Bridgewater 530 Route 22 East Bridgewater, New Jersey, 08807 Phone: 1-908-725-0800 http://hyatt.com/hyatt/summerfield/ February 9, 2016 Page 6