Horsechestnut Cream 60ml: £10
Contents
Base cream* horsechestnut (Aesculus hippocastanum), gotu kola (Centella asiatica),
peppermint (Mentha piperita)
Studies
Horsechestnut and the major active principle aescin, have been the subject of several
human studies (Sirtori, 2001) on chronic venous insufficiency (CVI) (e.g. Suter et al., 2006),
varicose veins and haemorrhoids. It has been shown to be effective in reducing symptoms
such as leg swelling, pain, heaviness, itching and bleeding and was as effective as
compression therapy in CVI.
There are several mechanisms of action through which horsechestnut may exert its benefits;
it may inhibit dilation or induce contraction of veins due to molecules such as histamine,
serotonin and certain prostaglandins and may inhibit enzymatic breakdown of tissue
compounds supporting veins and capillaries such as hyaluronic acid.
References
Sirtori CR. (2001) ‘Aescin: pharmacology, pharmacokinetics and therapeutic profile’.
Pharmacol Res. 44(3):183-93. Review.
Suter A, Bommer S, Rechner J. (2006) ‘Treatment of patients with venous insufficiency with
fresh plant horse chestnut seed extract: a review of 5 clinical studies’, Adv Ther. 23(1):17990.
*Base cream ingredients from ProLine Botanicals:
Meadow Park Industrial Estate  Bourne Road,
Essendine, Near Stamford  Lincolnshire PE9 4LF
Tel: +44(0) 1780 753366  +44(0) 1780 484610 fax GB
Company
4226789
VAT No.Reg
772No
1011
67
Proline INCI Listing
Base Cream
Aqua
Prunus Amygdalus Dulcis
Cetearyl Alcohol
Stearyl alcohol
Glycerin
Polysorbate 40
Cocos Nucifera
Isopropyl Myristate
Glyceryl Stearate
PEG-100 Stearate
Disodium hydrogen phosphate
Boxus chinensis
Sorbitan palmiate
Citric acid
Phenoxyethanol
Methylparaben
Ethylparaben
Butylparaben
Propylparaben
Isobutylparaben
Α-tocopherol acetate