AWARDS BioScience Undergraduate Research Program Minigrant

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Ashley Chan (Peterson)
3181 Margie Ave
SLC, UT 84109
(801) 910-9735
ashl.chan@gmail.com
EDUCATION
Bachelor of Science Degree, Biology
University of Utah (Spring 2006)
Undergraduate Laboratory Concentration: Genetics under Dr. Jon Seger
Member of BioScience Undergraduate Research Program
Secretary of BioScience Undergraduate Research Club
Teaching Assistant of Basic Laboratory Technique 2115
Presented research results at National Conference for Undergraduate Research
PROFESSIONAL EXPERIENCE
University of Utah—SLC, UT
Senior Laboratory Specialist/Lab Manager, Dr. Joshua Schiffman
Jan 2012-present
University of Utah—SLC, UT
Temporary Laboratory Technician, Dr. Ila Singh
Sept 2011-Dec 2012
SuperGen—SLC, UT
Contract Research Associate II, Dr. Jason Foulks
May 2011-Sept 2011
Myrexis (Myriad) Pharmaceuticals—SLC, UT
Research Associate II, Dr. Daniel Cimbora
February 2008-March 2011
Myriad Genetics—SLC, UT
Laboratory Technician II, James McCulloch
January 2006-February 2008
University of Utah—SLC, UT & HNL, HI
Research Assistant, Dr. Coleen Farmer/Dr. Ben Chan
May 2005-December 2005
University of Utah—SLC, UT
Laboratory Technician, Dr. Jon Seger
May 2003-May 2005
RELEVANT LABORATORY EXPERIENCE
Histological
 Immunohistochemistry
 FFPE sectioning (microtome)
Biochemical and Molecular
Biological
 PCR, q-PCR, RTPCR
 Sequencing
 Gel Electrophoresis—SDSPAGE, agarose gel
 Macromolecule
Blotting/Probing—Southern,
Northern, Western
 Protein/NA isolation and
purification
 Radiometric (33P) & ADP Glo
assays
 Electroporation
 Immunofluorescence
 Immunoprecipitation
 Flow Cytometry
 ELISA
Immuno/Physiological
 Cell culture—bacterial,
mammalian, primary, stem cell
 Stem Cell Differentiation
 Cellular cloning
 Transfection—liposome
 Xenograft preparation
 Cytotoxicity, proliferation
 Phenotypic Assays—2D Colony,
luciferase, fluorescence
 Mycoplasma Testing
Ecological
 Behavioral Observations
 Collection
Managerial
 Supply inventory & ordering
 Developing assays & protocols
 Budgeting
 Interviewing
 Training
 IACUC/IRB protocols
 Abstract/paper/grant writing,
proof reading & submission
Robotic Operations & Maintenance
 Liquid Handlers
 Sequencers
 PCR
 NA isolators
 Chemiluminescent
 Microplate Readers
 Spectrophotometers
 Flow Cytometers
Data Analysis
 R programming (some)
 Microsoft Office
 Copy Number
 Prism Graph
 Sequencher
 MacClade
 In-house Analyzation Software
Training & Certifications
 OSHA
 BSL2
 IRB
 HIPPA
 Radioactive
 Bloodborne Pathogen
 Good Laboratory Practices
 SDS
ADDENDUM 1
PUBLICATIONS
Peterson, A.L., Purwar, J., Mason, C., Cairns, B., Schiffman, J.S. Paraganglioma cell
lines: A novel clinical model for mutations within the succinate dehydrogenase complex.
(in prep)
Purwar, J., Pflueger, C., Srinivasan, R., Chan, A.L., Wysocka, J., Ellis, G., Schiffman,
J.D., Cairns, B.R. Profiling epigenetic misregulation in SDH mutated PGLs when
compared to cell type of origin, neural crest cells. (in prep, submission planned Dec.
2013)
Caulin, A., Peterson, A.L., Bharaska, S.V., Schiffman, J.S., Malley, C. The Elephant’s
Solution to Peto’s Paradox: Go Forth and Multiply TP53. (in prep submission planned
imminently)
Peterson, A.L., Mason, C., Jaromi, M., Purwar, J., Tripp, S., Ellis, G., Stewart, R.,
Cairns, B., Schiffman, J.S. CNV in paraganglioma tumors with known SDH mutations.
(in prep)
Keith D. Tardif, Aaron Rogers, Jared Cassiano, Bruce L. Roth, Daniel M. Cimbora, Rena
McKinnon, Ashley Peterson, Tom Douce, Rosann Robinson, Irene Dorweiler, Ryan
Doering, Thaylon Davis, Kirill Ostanin, Damon I. Papac, Vijay Baichwal, Ian
McAlexander, J. Adam Willardsen, Michael Saunders, Christophe Hoarau, D. Vijay
Kumar, Daniel A. Wettstein, Robert O. Carlson, Brandi L. Williams. Characterization of
the Cellular and anti-Tumor Effects of MPI-0479605, a Small Molecular Inhibitor of the
Mitotic Kinase MPsl. Mol Cancer Ther. 2011 Oct
Bursavich, M.G., Parker, D.P., Willardsen, A., Gao, Z., Davis, T., Ostanin, K., Robinson,
R., Peterson, A.L., Cimbora, D.M., Zhu, J., Richards, B. 2-anilin-4-aryl-1,3-thiazole
inhibitors of valosin-containing protein (VCP or p97). Bioorg Med Chem, 2010 Mar
1;20(5):1677-9
Roeser-Mueller, K., Peterson, A.L., Strohm, E., Stubblefield, J.W., Seger, J., Kaltenpoth,
M. Phylogentic relationships among Philanthinae (Hymenoptera: Sphecidae). (in review
PLOS)
Chan, B. K., Peterson, A.L., and C. G. Farmer. 2007. Dendrobates auratus (Green and
Black Poison Dart Frog) Larval Predation. Herpetological Review 38(3): 321-322
Chan, B.K., Peterson, A.L., Farmer, C. Post-depositional paternal care of larvae in a
tropical anuran. Herpetological Review (in prep)
POSTERS
Chan, A.L., Caulin, A.F., Bhaskara, S., Peterson, E., Maley, C.C., Schiffman, J.D. Peto’s
Paradox: Is increased apoptosis the answer to cancer resistance?
Purwar, J., Pflueger, C., Srinivasan, R., Chan, A.L., Wysocka, J., Ellis, G., Schiffman,
J.D., Cairns, B.R. Profiling epigenetic misregulation in paragangliomas
Hawkins, S., Chan, A.L., Abegglen, L., Jones, D., Burt, R., Mason, C., Schiffman, J.D.
Copy Number Analysis to determine genetic alterations in paired primary and metastatic
colorectal cancer samples
Foulks, J.M., Xu, Y., Saunders, M., Liu, X.H., Brenning, B., Clifford, A., Wilkes, M.,
Luo, B., Lai, S., Merx, S., Chan, A., Huang, L., Vollmer, D., Senina, A., Liu, J., Ho, K.,
McCullar, M.V., Kanner, S.B. Second generation PIM inhibitors exhibit improved
activity in solid tumor models
Boniface, J.J., Baichwal, V.R., Cimbora, D.M., DeMie, L., Fleischer, T.C., Gassman,
A.D., Ghaffari, S., Green, J.P., Flick, J.S., Terry-Lorenzo, R.T., Papac, D.I., Peterson,
A.L., Robinson, R., Carlson, R.O. Basal NAD levels and Nampt expression correlates
with in vitro and in vivo sensitivity of tumor cell lines to the Nampt Inhibitor MPC-9528
Fleischer, T.C., Baichwal, V.R., Boniface, J.J., Cimbora, D.M., DeMie, L., Douce, T.B.,
Gassman, A.D., Papac, D.I., Peterson, A., Robinson, R., Terry-Lorenzo, R.T., Carlson,
R.O. Coadministration of nicotinic acid with the Nampt inhibitor MPC-9528 enhances
anti-tumor activity in Naprt deficient cancer cells in culture and in xenografts
Boniface, J.J., Baichwal, V.R., Bradford, C.L., Peterson, A.L., Cimbora, D.M., Demie,
L., Flick, J.S., Gassman, A.D., Gordillo, R., Fleischer, T.C., Green, J.P., Lockman, J.W.,
Murphy, B.R., Papac, D.I., Robinson, R., Terry-Lorenzo, R.T., Willardsen, J.A., Carlson,
R.O. MPC-9528, a cancer metabolism inhibitor, demonstrates greater therapeutic index in
a Naprt1 deficient cancer xenograft model with co-administration of nicotinic acid
Richards, B., Cronin, M., Seager, N., Niederjohn, J. Baichwal, V. Peterson. A.L.,
Robinson, R., Hess, M., Davis, T. Papac, D. Suzuki, K., Holcomb, R., Carlson, R.
Cellular and In Vivo Properties of MPI-0485520, a Novel and Potent Small Molecule
Inhibitor of IKKε
AWARDS
BioScience Undergraduate Research Program Minigrant to study Phylogentic
relationships among Philanthinae. Total award: $14,480, (5/03-5/05)
ADDENDUM 2
REFERENCES
Joshua Schiffman, Director, Medical Director/Associate Professor at Huntsman Cancer
Institute
Joshua.schiffman@hci.utah.edu or 801-587-4745
Dan Cimbora, Clinical Research Scientist at Myrexis Pharmaceuticals
dlcimbora@comcast.net or 801-485-3477
Harry Austin, (formerly) Scientist II at Myrexis Pharmaceuticals
harry_austin09@comcast.net or 801-214-7800
Jason M. Foulks, Senior Manager of Discovery Biology at Astex Pharmaceuticals
(formerly SuperGen Inc)
Jason.foulks@astx.com or 801-386-2974
Scott Morham, (formerly) Director of Research Services at Myrexis Pharmaceuticals
Vaccinia@comcast.net
Mark Wolf, Supervisor at Myriad Genetics
mwolf@myriad.com
Dr. Jon Seger, Professor of Biology at University of Utah
seger@biology.edu or 801-581-4758
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