Table 1: Socio-demographic, clinical and phenomenological profile of patients (diagnosed according to DSM-IV)
DemographicVariables
1.
Age (years)
2.
Sex
3.
Number
(Percentage)
N=80
37.46 (16-80)*
Male
58 (72.50)
Female
22 (27.50)
Not employed
34 (42.5)
Semiskilled
22 (27.5)
Skilled
4 (5.0)
Unskilled
20 (25.0)
Occupation
4.
Years of schooling received
9.2 (0 to 21)*
5.
Age at onset of illness(years)
29 (12 to 70)*
6.
Total duration of illness (months)
105.5 (0.5-432)*
7.
Duration of untreated bipolar illness (DUBI) in months
13.20 (0.5-240)*
8.
Treatment Response
Complete
51(63.75)
No response
1 (1.25)
Ongoing
7 (8.75)
Partial
21 (26.25)
9.
Marriage
Status
Married
58 (72.50)
Unmarried
22 (27.50)
Remained unmarried due to illness?
5 (6.25)
Married before/after onset of illness
Before
46 (57.5)
After
12 (15.0)
Disharmonies due to illness
23 (28.75)
Divorce/separation due to illness
3 (3.75)
42 (52.5)
8.
Substance Consumption/ Abuse
6 (7.5)
9.
Family History Of Bipolar Illness
12 (15.0)
10.
Family History Of Other Psychiatric Illness
* Mean (Range)
Table 2: Distribution of patients with classic bipolar disorder according to different classifications used for diagnoses of bipolar affective
disorders.
Patients belonging to the classic bipolar symptom group (N=59)
Patients
included
DIAGNOSTIC SYSTEMS
Jules Angst
classification
Patients having
discrete episodes
of mania/s
Patients having
episodes of mania
and depression in
the course of their
illness
Akiskal’s classification
i. Bipolar-I with
psychotic features
33
ii. Bipolar-I
without psychotic
features
iii. Mania with
psychotic features
TOTAL
50
i. Mania without
psychotic symptoms
1
25
ii. BMD-I single
manic episode
6
ii. Mania with
psychotic symptoms
3
1
iii. BMD-I depression
2
21
iv. BMD-I mixed
episode
0
v. BMD-I in
remission
1
iii. BPAD manic
without psychotic
symptoms
iv. BPAD- mania
with psychotic
features
v. BPAD- severe
depression without
psychotic symptoms
vi. BPAD- severe
depression with
psychotic symptoms
vii. BPAD- in
remission
TOTAL
TOTAL
59
ICD-10
i. BMD-I mania
59
i. Bipolar-I
DSM-IV-TR
59
TOTAL
59
31
1
1
1
59
Table 3: Distribution of the patients with less common forms of bipolar disorders according to different classifications used for
diagnoses of bipolar affective disorders.
Patients
included
Patients belonging to the less common forms of bipolar disorders (OTHERS) group (N=21)
DIAGNOSTIC SYSTEMS
Akiskal’s
classification
Jules Angst
classification
 Episodes of
hypomania
and
depression
(n=3)
Bipolar-2
 Persistent
psychotic
symptoms
and episodic
affective
symptoms
(n=13)
 Episodes of
hypomania and
mild
depression
Cyclothymic
(n=1)
disorder
 H/O
affective
symptoms
associated
with use of
DSM-IV-TR
ICD-10
3
Bipolar-2
3
BMD-II
3
BPAD
3
0
Bipolar-1/2
13
Schizoaffective
disorder
13
Schizoaffective
disorder
13
0
Cyclothymic disorder
1
Cyclothymic disorder
1
1
Substance induced
mood disorder
1
Persistent
mood/affective
disorder-unspecified
1
1
0
Bipolar-III 1/2
drug/
substance
(n=1)
 Dementia
with
affective
symptoms
(n=2)
 Persistent
hypomanic
symptoms
and
intermittent
psychotic
features
(n=1)
TOTAL (N=21)
0
Bipolar-VI
2
0
4
BMD-NOS
BMD-NOS
19
2
Affective disordersunspecified
2
1
Affective disordersunspecified
1
21
21
Table 4: Percentage of patients with bipolar disorder and its subgroups diagnosed (and missed) by various diagnostic classification systems and
comparison of these classifications used for diagnoses of bipolar affective disorders.
JULES ANGST
classification
AKISKALs
classification
DSM-IV-TR
classification
ICD-10 classification
Patients diagnosed with
bipolar disorder
63 (78.75)
78 (97.50)
80 (100)
80 (100)
Patients diagnosed with
Classic bipolar disorder
subgroup
59 (100)
59 (100)
59 (100)
59 (100)
Patients diagnosed with
less common forms of
bipolar disorders
(OTHERS Subgroup)
4 (19.05)
19 (90.48)
21 (100)
21 (100)
Patients in whom
diagnosis was missed/not
available in the
classification
17 (21.25)
2 (2.50)
0 (0.00)
0 (0.00)
* Data presented as number (percentage)
Table 5: Individual diagnoses in patients who did not receive any diagnosis in the different classification systems.
Distribution in JULES ANGST classification
Diagnosis missed by the classification
No. of patients
TOTAL
i.
Schizoaffective disorder
13
17
ii.
Substance induced mood disorder
1
(21.25% of total 80 patients)
iii.
Dementia with affective features
2
iv.
BMD-NOS/Unspecified affective disorders
1
Distribution in AKISKALs classification
Diagnosis missed by the classification
No. of patients
TOTAL
i.
Cyclothymia
1
2
ii.
BMD-NOS/Unspecified affective disorders
1
(2.5% of total 80 patients)
Distribution in DSM-IV-TR classification
Diagnosis missed/not available in the classification
No. of patients
TOTAL
NIL
0
0
Diagnosis missed/not available in the classification
No. of patients
TOTAL
NIL
0
0
Distribution in ICD-10 classification