O34 CHALLENGING THE OLD TRADITIONS IN RENAL TRANSPLANTATION: THE FIRST UK ENHANCED RECOVERY AFTER RENAL TRANSPLANTATION Halawa, A, Gray, C, Rowe, S, Plant, M, Hanvere, J, Abbas, G, Boyes, S, Nathan, C, Roberts, F Sheffield Kidney Institute Sheffield Teaching Hospitals INTRODUCTION: Traditional management of postoperative pain and management of urinary catheter, lines and drains led to longer hospital stay and subsequent delayed recovery. There has been anxiety among renal transplant surgeons and physicians that enhanced recovery principles cannot be applied to these immunocompromised patients who are ASA III. AIM: To apply the principle of enhanced recovery programme in renal transplant recipients and assess the changes in the quality of patients’ care. METHODS: Patient education and discharge planning are commenced on admission. Intraoperative management including goal-directed fluid management using Transoesophageal Doppler was also implemented to achieve adequate fluid balance and avoid central lines. Intrathecal diamorphine and transverses abdominis plane block (TAP block) were used to minimise the use of systemic morphine (PCA) to achieve improved postoperative analgesia. Patients were commenced oral intake few hours after the operation. Urinary catheters were removed 4 days after the operation. This enabled early mobilisation and patient education resulting early discharge without increase in the readmission rate. RESULTS: Postoperative PCA requirement was significantly reduced in ER patients compared to standard recovery patients (P<0.001) demonstrating better postoperative analgesia. The length of stay was significantly reduced (P<0.001) for living transplant recipients (Mean 5.2 vs. 9.4 days, Median 5 vs. 9 days) and for deceased donor transplant recipients (Mean 5.2 vs. 11.5 days, Median 5 vs. 8.5 days) compared to patients who had traditional recovery. There is significant correlation between LOS and morphine requirement (r = 0.55, P <0.001). Implementing ER saves 2160 pounds per patients (533 pounds per day). CONCLUSION: Our study demonstrates that ER benefits both forms of renal transplantation with better quality of care and no difference in LOS.