SURGICAL AND FUNCTIONAL OUTCOMES OF LESS PARTIAL NEPHRECTOMY WITHOUT ISCHEMIA F. Berardinelli, L. Cindolo, F. Neri, F. Tamburro, L. Schips (Vasto) Aim of the study To report on surgical and functional outcomes of unclamp LESS nephron-sparing surgery (NSS). Materials and methods Prospective evaluation of preoperative and postoperative variables of patients undergoing to the LESS-NSS without ischemia between April 2009 and March 2012. The indications were single, exophytic, cortical, small renal masses. The procedure was performed through a transperitoneal approach. A pararectal open Hasson access technique was preferred. A multichannel port was used and a combination of articulating, bent and conventional laparoscopic instruments were used. Demographic data and ASA class-risk, operative time, specimen and tumor size, estimated blood loss, transfusion requirements, pre- and postoperative renal function and hemoglobin, length of stays (LOS), oral intake, pain assessment (VAS), complications according to DindoClavien classification were recorded. Results Twenty-one patients were included (mean operative time 111±41min, mean blood loss 196±195mL, mean tumor size 2±0.3cm). Neither conversion to open surgery nor transfusions occurred. Four patients required conversion to standard laparoscopy. We recorded 1 Clavien II, 1 Clavien IIIa, 1 Clavien IV. Pathologic examination revealed: 14 RCC (pT1a), 1 angiomyolipoma, 2 oncocytoma, 5 complex renal cysts. With a postoperative VAS of 2.1±1.2 the LOS was 4.4±1.9 days. At 16±11 months follow-up, neither port-site, local, distant recurrence nor eGFR variation were detected. Discussion LESS unclamp-NSS in selected renal masses is safe and feasible procedure, provides postoperative outcomes overlapping the standard laparoscopy and ensures subjective satisfaction. Conclusions In our opinion the key of success is the rigorous selection of the cases.