CME 9 and 11 April 2013 Iran Faculty: Shahrzad Ossarek, MD; Mitra Mahdavi, MD, PhD; Pablo Urena, MD, PhD; Marc De Broe, MD, PhD 09h00 Introduction 09h05 Physiology/physiopathology of mineral metabolism in progressive renal failure Calcium balance in patients with renal failure (CKD I-V; HD/PD) Total calcium-ionized calcium Diagnosis of different forms of ROD / biomarkers Case reports: N=2 10u45 Coffee break 11h00 Vitamine D Metabolism, pharmacological activities Insufficiency/depletion in renal failure How to restore the vit D stock in patients with renal failure Case report: N=1 FGF23 FGF23 in the regulation of phosphate metabolism FGF23 useful in the monitoring of phosphate balance in renal failure Klotho and mineral bone metabolism in normal and renal failure patients Case reports: N=1 12h30 Lunch pause During this pause a continuous projection of a video demonstrating technique of prelevation, sample processing, indication ,analysis and reporting of a bone biopsy in a patient. 13h30 Vacular calcifications Physiopathology Screening yes or no ? How ? Treatment / prevention Case report: N=1 14h30 Mineral metabolism postrenal transplantation Case report: N=1 Mineral metabolism in children with renal failure 15h15 Coffee break 15h40 Treatment of hyperparathyroidism Surgery versus medical treatment Localization tests on parathyroid glands before surgery ? Novel agents in hyperparathyroidism Hyperphosphatemia How to treat ? Calcium versus non-calcium phosphate binders Use of biphosphonates in renal failure HD versus PD as treatment modality in the mineral metabolism disturbances Case report: N=2 17h00 Panel discussion: questions/answers 17h30 Take home messages and closure