Supplementary Table 1. Metabolites significantly differentially expressed and their related
pathways (top 20).
Metabolites
Acetic acid
Benzeneacetic acid
Benzoic acid
Butanoic acid
D-gluconic acid
Pathways
Microbial metabolism in diverse environments
Metabolic pathways
Metabolism of xenobiotics by cytochrome P450
Phenylalanine metabolism
Chlorocyclohexane and chlorobenzene degradation
Histidine metabolism
Thiamine metabolism
Naphthalene family
Chloroalkane and chloroalkene degradation
Naphthalene degradation
Aminobenzoate degradation
Styrene degradation
Chemical carcinogenesis
Cyclooxygenase inhibitors
Phenylalanine metabolism
Aminobenzoate degradation
Microbial metabolism in diverse environments
Benzoic acid family
Biosynthesis of alkaloids derived from shikimate pathway
Metabolic pathways
Biosynthesis of secondary metabolites
2-Oxocarboxylic acid metabolism
Glucosinolate biosynthesis
Valine, leucine and isoleucine biosynthesis
Butanoate metabolism
Biosynthesis of antibiotics
Protein digestion and absorption
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Propanoate metabolism
Carbon fixation pathways in prokaryotes
Pantothenate and CoA biosynthesis
Biosynthesis of plant secondary metabolites
Biosynthesis of alkaloids derived from histidine and purine
Microbial metabolism in diverse environments
Carbon metabolism
Biosynthesis of amino acids
Carbohydrate digestion and absorption
Metabolic pathways
Microbial metabolism in diverse environments
Pentose phosphate pathway
Inositol phosphate metabolism
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
Carbon metabolism
D-glucose
D-sorbitol
Glycine
L-threonine
Streptomycin biosynthesis
Biosynthesis of antibiotics
Amino sugar and nucleotide sugar metabolism
Starch and sucrose metabolism
Polyketide sugar unit biosynthesis
Carbohydrate digestion and absorption
Metabolic pathways
Biosynthesis of plant secondary metabolites
Glycolysis / Gluconeogenesis
Biosynthesis of secondary metabolites
Central carbon metabolism in cancer
Galactose metabolism
Microbial metabolism in diverse environments
Glucagon signaling pathway
Pentose phosphate pathway
Overview of biosynthetic pathways
Biosynthesis of phenylpropanoids
Carbon metabolism
AMPK signaling pathway
Biosynthesis of terpenoids and steroids
Fructose and mannose metabolism
Phosphotransferase system (PTS)
Galactose metabolism
ABC transporters
Metabolic pathways
Glycine, serine and threonine metabolism
Primary bile acid biosynthesis
Biosynthesis of amino acids
Protein digestion and absorption
Purine metabolism
Thiamine metabolism
Metabolic pathways
Biosynthesis of antibiotics
Glutathione metabolism
Drug metabolism - cytochrome P450
Microbial metabolism in diverse environments
Monobactam biosynthesis
Cysteine and methionine metabolism
Arginine and proline metabolism
Cyanoamino acid metabolism
Glyoxylate and dicarboxylate metabolism
Methane metabolism
Porphyrin and chlorophyll metabolism
Sulfur metabolism
Protein digestion and absorption
Vitamin B6 metabolism
Porphyrin and chlorophyll metabolism
Metabolic pathways
Monobactam biosynthesis
Aminoacyl-tRNA biosynthesis
Myo-inositol
Phosphate
Biosynthesis of plant secondary metabolites
Glycine, serine and threonine metabolism
Valine, leucine and isoleucine biosynthesis
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of antibiotics
Biosynthesis of amino acids
ABC transporters
Mineral absorption
Methane metabolism
Overview of biosynthetic pathways
Streptomycin biosynthesis
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Inositol phosphate metabolism
Phosphatidylinositol signaling system
Metabolic pathways
Endocytosis
Regulation of actin cytoskeleton
Galactose metabolism
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
Biosynthesis of antibiotics
Ras signaling pathway
NF-kappa B signaling pathway
Regulation of autophagy
Phagosome
Fc gamma R-mediated phagocytosis
Cholinergic synapse
Long-term depression
Tuberculosis
Pathways in cancer
Pentose phosphate pathway
Inositol phosphate metabolism
Terpenoid backbone biosynthesis
Carbon metabolism
Methane metabolism
Lysosome
Calcium signaling pathway
Sesquiterpenoid and triterpenoid biosynthesis
Benzoxazinoid biosynthesis
Zeatin biosynthesis
Sphingolipid signaling pathway
N-Glycan biosynthesis
PI3K-Akt signaling pathway
Indole diterpene alkaloid biosynthesis
Monoterpenoid biosynthesis
Cholinergic synapse
Carbon fixation pathways in prokaryotes
GnRH signaling pathway
Small cell lung cancer
RNA degradation