DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY
Faculty of Pharmacy, Comenius University
832 32 Bratislava 3, Odbojárov 10
Garrant: Assoc. Prof. Stankovičová T., MD., CSc.
Subject: Pathology (obligatory)
Year: 2nd
Term: Winter 2013
Weekly hours: 2/2(E)
Credits: 5
Lecturers: Assoc. Prof. MD. Stankovičová T., CSc., Assoc. Prof. PharmD.
Klimas J., PhD., Assoc. Prof. PharmD. Hrabovská A., PhD., PharmD.
Foltánová T., PhD., prof. PharmD. J.Kyselovič, CSc.
Educational period: 23.9.2013-20.12.2013
Examination period: 7.1.2014-14.2.2014
Syllabus of the Lectures
24/9: Introduction to patology. Concept of disease and illness – etiology (mechanical,
chemical, physical, biological injury), pathogenesis, clinical manifestations,
classification, and incidence of diseases.
doc. MD. Stankovičová T., PhD.
1/10: Principles of molecular pathogenesis and genetics. Genetic abnormalities
(chromosomal abnormalities, sex chromosome disorders, gene mutations and
disorders), developmental disorders. Hereditary diseases. Hereditary forms of
malignant diseases.
prof. PharmDr. J. Kyselovič CSc
8/10: General symptomatology – causes, pathomechanisms
Pain – etiopathogenesis, symptomatology, consequences, prophylaxis
doc. MD. Stankovičová T., PhD.
15/10: Diseases of the arteries.
Atherosclerosis. Hypertension. Etiopathogenesis,
symptomatology, compensatory mechanisms, sequelae
doc. MD. Stankovičová T., PhD.
22/10:
Ischemic disease of the heart. Myocardial Infarction.
symptomatology, compensatory mechanisms, complications.
doc. MD. Stankovičová T., PhD.
Etiopathogenesis,
29/10: Rhythm disturbances. Heart failure. Etiopathogenesis, symptomatology, compensatory
mechanisms, sequelae.
doc. PharmD. Klimas J., PhD.
5/11:
Selected disorders of the nervous system. Etiopathogenesis, symptomatology
consequences. Disturbances in the sleep, memory disturbances, pathophysiology of
ANS
doc. PharmD. Hrabovská A., PhD.
12/11 Diseases of the respiratory systém. Cough, Astma. Bronchitis, Obstructive airways
disease. Respiratory insufficiency. Etiopathogenesis, symptomatology, sequelae
doc. PharmD. Klimas J., PhD.
19/11:
Alterations of the digestive function. Basic manifestations of GIT disorders. Peptic
ulceration - disturbances of the Gastric Juice Production. Role of Helicobacter pylori,
Reflux oesophagitis. Liver diseases - jaundice, hepatitis, cirrhosis, failure.
PharmD. Foltánová T., PhD.
26/11: Pathophysiology of renal disorders. General symptomatology, Glomerular diseases.
Tubulo-interstitial disorders. Renal Failure. Etiopathogenesis, symptomatology,
compensatory mechanisms, sequelae.
doc. MD. Stankovičová T., PhD.
3/12: Basic concepts of tumor pathology. Definitions and epidemiology. Classification.
Benign and malignant neoplasia. Clinical manifestation, Metastasis, prognosis
doc. PharmD. Klimas J., PhD., PharmD. Hrabovská A., PhD.
10/12: Psychiatric disorders - anxiety and personality disorders, depression, bipolar disorder,
schizophrenia
doc. PharmD. Hrabovská A., PhD.
17/12: Unconsciousness. Shock. Colaps, hypotension.
doc. PharmD. Klimas J., PhD.
Time: Tuesday 9.20-11.05h
Place: Odbojarov 10, room No: 101
30/8/2013 Bratislava
Assoc. Prof. RNDr. I. Tumová, PhD.
Head of the department
Assoc. Prof. MD. T. Stankovičová, PhD.
Guarantor
DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY
Faculty of Pharmacy, Comenius University
832 32 Bratislava 3, Odbojárov 10
Garrant: Assoc. Prof. Stankovičová T., MD., CSc.
Subject: Pathophysiology (obligatory elected)
Year: 2nd
Term: Winter 2013
Weekly hours: 2/0 (E)
Credits: 2
Lecturers: Assoc. Prof.. MD. Stankovičová T., CSc., Assoc. Prof. PharmD.
Klimas J., PhD., Assoc. Prof.. PharmD. Hrabovská A., PhD., PharmD.
Foltánová T., PhD., prof. PharmDr. J.Kyselovič CSc.
Educational period: 23.9.2013-20.12.2013
Examination period: 7.1.2014-14.2.2014
Syllabus of the Lectures
24/9:
Changes in Acid-base Balance – acidosis, alkalosis, Changes in Electrolytes.
Etiopathogenesis, compensatory mechanisms, complications
doc. MD. Stankovičová T., PhD.
1/10
Metabolic Disorders, Metabolic Syndroma, Dyslipidemias, Disorders of vitamines,
Nutritional alteraions as a risk factor. Obesity
doc. PharmD. Klimas J., PhD.
8/10:
Interaction between organism and environmental conditions. Adaptation and Stress
doc. MD. Stankovičová T., PhD.
15/10: Disturbances of Circulation. Stroke, Pulmonary hypertension. Renal hypertension,
ischemia in mesenterial cicrulation.
doc. MD. Stankovičová T., PhD.
22/10: Changes in cardiac function. Cardiomyopathy. Congenital heart diseases.
Valvular diseases. Etiopathogenesis, compensatory mechanisms, complications.
doc. MD. Stankovičová T., PhD
29/10: Diseases of the Skin. Infectious, inflammatory, and allergic skin responses.
Childhood skin Disorders (Measles, Monkey pox, Mumps, Rubella, Smallpox).
Integumentary manifestations of systemic disease.
PharmD. Foltánová T., PhD.
5/11:
Alterations of the renal and urinary tract function. Nephrotic sy, pyelonephritis,
stones, incontinency.
doc. MD. Stankovičová T., PhD
12/11:
Diseases of the airways. Tuberculosis, Interstitial diseases of the lung, fibrosis.
Diseases of pleura
doc. PharmD. Klimas J., PhD.
19/11: Selected alterations of intestines. Malabsorption – celiac disease, inflammatory bowel
disease – m. Crohn, ulcerative colitis, apendicitis;
Disorders of the gall bladder.
PharmD. Foltánová T., PhD
26/11
Infectious processes – epidemiology, transmission, pathomechanisms, types of
microorganisms - bakteria, viruses. Endocarditis, meningitis, pneumonia, diarrhea,
sepsis.
prof. PharmDr. J.Kyselovič CSc
3/12:
Selected infectious diseases induced by fungi, parasites
prof. PharmDr. J.Kyselovič CSc
10/12: Pathophysiology of Osteoarticular and Connective Tissues. Joint and muscles
disease. Rheumatic disorders. Osteoarthrosis, myasthenia gravis, myotonia,
dystrophy
doc. MD. Stankovičová T., PhD.
17/12: Free topic for demand
doc. MD. Stankovičová T., PhD.
Time: Tuesday 16.40-18.25h
Place: Kalinčiakova 8, room No: K 105B
30/8/2013 Bratislava
Assoc. Prof. RNDr. I. Tumová, PhD.
Head of the department
Assoc. Prof. MD. T. Stankovičová, PhD.
Guarantor
Syllabus of the Seminars and Practical Training
Pathology 2013/2014
Educational period: 23.9.2013-20.12.2013
Examination period: 7.1.2014-14.2.2014
Teachers: PharmD. Foltánová T., PhD. PharmD. Kiliánová. Z., PhD.,
PharmD. Kráľová E., PhD., PharmD. Jankyová, S., PhD., PharmD.
Čorejová A., PhD.
25/9: Disorders of the differentiation and morphogenesis. Endocrine control, genetic,
nutritional, environmental factors.
PharmD. Foltánová, PhD.
2/10: Disorders of the growth. Hypertrophy, hyperplasia, atrophy, hypoplasia, metaplasia,
dysplasia, neoplasia.
PharmD. Jankyová, PhD.
9/10: Causes and mechanisms of cellular Injury. Dystrophy, necrosis, apoptosis, repair,
regeneration. Aging. Death – etiopathogenesis, manifestations.
PharmD. Kráľová, PhD.
16/10: Mechanisms of disturbances in vascular circulation - trombosis, embolism,
ischemia, infarction, shock
Test (topics 1.-3.)
PharmD. Foltánová, PhD.
23/10 Inflammation . etiology, acute, chronic, pathomechanisms. role of blood elements,
mediators. Characteristics local (rubor, calor, tumor, dolor, functio laesa) and General
(temperature). Oedema
PharmD. Čorejová, PhD.
30/10: Disorders of the Senzory Systems, Diseases of the Eyes, Ear.
Seminar: glaucoma, cataracts
retinopathy
errors of refraction
otitis, vertigo, Meniere disease
PharmD. Kráľová, PhD.
6/11: Hematologic Disorders. Disorders of Blood Coagulation and Haemostasis
Seminar: coagulopat hies
trombocythopathies
vasculopathies
anaemias
leukemias
PharmD. Kráľová, PhD.
13/11: Diseases of the Nervous System.
Seminar: epilepsy
neurodegenerative disorders (Alzheimer Disease, Parkinson Disease)
PharmD. Kiliánová, PhD.
20/11: Respiratory Diseases
Seminar: flu, tonsilitis
bronchial asthma,
pneumonia – atypical pneumonia, aspiration
respiratory distress sy
PharmDr. Jankyová, PhD.
27/11: Pathology of GIT
Seminar: nausea, vomiting
dysphagia, intestinal gas
altered Nutritional Balance, diets
Test (topics 4.-9.)
PharmDr. Foltánová, PhD.
4/12: Metabolic and Nutritional Bone Alterations.
Seminar: disorders of calcium homeostasis (endocrine disturbances)
osteoporosis, osteomalacia,
Paget disease
PharmDr. Kiliánová, PhD.
11/12: Alterations of the Hormonal Regulation.
Seminar: Diabetes Mellitus, type I and II.
Disorders of the Thyroid Function.
Immunopathology, Alterations in Immune function.
Seminar: hypersensitivity
autoimmune diseases (lupus)
Immunodeficiency (primary, acquired – AIDS)
Test (topics 10.-12.)
PharmDr. Jankyová, PhD.
18/12: Conclusions, remarks and additional tests
PharmD. Foltánová T., PhD., PharmD. Kiliánová. Z, PhD., PharmD. Kráľová E., PhD.,
PharmD. Jankyová, S., PhD., PharmD. Čorejová A., PhD.
Time: Wednesday according to the time schedule
Place: Kalinčiakova 8, 4th floor, room No K 409.
30/8/2013 Bratislava
Assoc. Prof. RNDr. I. Tumová, PhD.
Head of the department
Assoc. Prof. MD. T. Stankovičová, PhD.
Guarantor
Literature:
Essentials of Pathophysiology, 3rd edition, by C.M. Porth. Ed. Lippincott and Wilkins:
Philadelphia, 2011, ISBN 0781770874
General and Systemic Pathology, 4th edition, by J.C.E. Underwood. Ed. Churchill
Livingstone: NY, 200, ISBN 0443073341/9780443073342
Textbook of pathology, 6th edition, by H. Mohan: Jaypee Brothers Medical Publishers (P)
Ltd, New Delhi, India, 2010, ISBN 978-81-8448-702-2
Human Anatomy, Physiology, and Pathophysiology. by Thewes G., Mutschler E., Vaupel P.,
Ed. Elsevier, Amsterdam, 1985. 812pp.
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Where can you buy the books? Eurobooks, Jesenského ul. 5-9, Bratislava