Chem 208 Spring 2014 Organic Chemistry II Instructor: Dr. Shelli Waetzig Email: swaetzig@framingham.edu Office: Hemenway Hall (HH) 336G Phone: 508-626-4784 Class meets: Lab meets: M, W, R, F 10:30 am – 11:20 am HH 323 M 2:30-6:20 pm or W, R 1:30-5:20 pm HH 344 Office Hours: M - 2:30 -3:30 pm, R – 9:30 am - 10:30 am, F - 1:00-2:00 pm (or by appointment) Required Texts/Supplies: Recommended Texts: Organic Chemistry, 8th edition, by L. G. Wade, Jr., Pearson, New York, 2013 Organic Laboratory Techniques Fessenden, Fessenden, and Feist, 3rd Edition, Brooks/Cole, Pacific Grove, CA, 2001 Molecular Models (Molecular Visions Modeling Kit Recommended) Scientific calculator (graphing calculators not allowed on exams/quizzes) Download ChemDraw, provided by the University via the following link: http://sitelicense.cambridgesoft.com/sitelicense.cfm?sid=2580 Organic Chemistry Solutions Manual Jan William Simek, Boston, 8th edition, 2013 (A copy is on reserve in Library) Prerequisite: CHEM207 Organic Chemistry I Course Objectives: Expand your basic knowledge of organic chemistry by developing a deeper understanding of the reactivity of functional groups such as aromatic rings, dienes, alcohols, amines, aldehydes, ketones, carboxylic acids and their derivatives. Further your understanding of “electron pushing”, so that you are able to propose reasonable reaction mechanisms. Use the fundamentals of functional group reactivity to develop multi-step syntheses of organic molecules. Use NMR spectroscopy, along with IR spectroscopy and mass spectrometry, to deduce unknown organic structures. Continue to develop practical laboratory skills Attendance: All students are expected to attend class. If a situation arises where you need to miss class, it is YOUR responsibility to obtain any notes and material covered that day. Communication: I maintain an open door policy, so please stop by! You may also set up an appointment outside of office hours by emailing me. Email is a very efficient method of communication, although I generally do not check this in the evening or on weekends. Check Blackboard often for updates!!! I will post many things to the course Blackboard site, including solutions to quizzes, exams, and problem sets, as well as handouts for laboratory or class. Chem 208 Spring 2014 Assignments: Reading assignments, chapter objectives, and suggested problems from the textbook will be posted for each chapter on Blackboard. An additional problem set may be posted on Blackboard prior to each exam. Although problem sets will not be collected or graded, they should be an integral part of your studying regiment. They will augment your understanding of the course. Practice, practice, practice!!!!!! You cannot become a concert pianist by just reading the music and this course is no different. ADA Compliance: Students with documented disabilities should consult with Office of Academic Support (CASA) and contact me privately as early as possible to discuss your specific needs and to coordinate reasonable accommodations. Grading Policy: The grade for the class will be based on a total of 930 points. Laboratory 150 points Quizzes (9 x 20 pts) 180 points Exams (4 x 100 pts) 400 points Final Exam 200 points Laboratory: The laboratory is an integral part of the course. All experiments MUST be completed. If you know you must miss a lab, let the instructor know at least a week in advance so that proper accommodations can be made. Failure to attend lab will result in a substantial penalty (beyond that of losing the points for the missed lab). Any student who misses more than one laboratory period without a written excuse by the Dean of Students will fail the entire course. Appropriate laboratory attire is required for participation. Refer to laboratory syllabus for more detailed information. Quizzes: Quizzes will be given weekly on Fridays, at the beginning of the class period. Make-up quizzes will not be given, nor will extra time be given to students who are late. There will be ten quizzes and each student will have their lowest quiz score dropped at the end of the semester. Exams: The four exams are scheduled for: February 12th, March 12th, April 9th, April 30th. Students must contact the instructor if a conflict arises with the exam date, prior to test date. Make-up exams will only be given for students with a written excuse from the Dean of Students and prior notice for missing the original exam. There will be a cumulative final exam given during finals week. The final exam is scheduled for Tuesday, May 6th from 8:00-11:00 am. The final will only be given during the time stated by the University. No exceptions will be made. Given that Organic Chemistry is a cumulative subject, this course will require a fundamental knowledge of previous concepts for all quizzes/exams. NOTE: You must earn passing grades in both the lecture and laboratory components of CHEM208 to pass the course. Any student earning a failing grade in either component will subsequently fail the course. Chem 208 Spring 2014 Academic Integrity: Refer to pages 32 through 34 in the FSU Undergraduate catalog for a full description of the academic honesty policy. (http://www.framingham.edu/undergraduatecatalogs/documents/1112/academic-regulations.pdf.) There is a zero-tolerance policy on cheating and plagiarism (including quizzes, exams, and lab reports). If you have any questions regarding this policy, please contact me. Please be respectful during class and refrain from the following activities: 1. Using your phone (sending or receiving calls, text messages, emails, etc.) 2. Talking with your neighbor 3. Using laptop computers (you will find that these are inefficient for taking notes in this course) 4. Leaving before the class period is complete Approximate Course Outline: Week of Class Topic Jan. 20 Intro/Aromaticity Jan. 27 Aromatic Reactivity Feb. 3 Aromatic Reactivity Feb. 10 NMR Spectroscopy Feb. 17 NMR Spectroscopy Feb. 24 Reaction of Dienes Mar. 3 Reactions of Alcohols Mar. 10 Ketones and Aldehydes Mar. 17 Spring Break Mar. 24 Amines Mar. 31 Carboxylic Acids Apr. 7 Carboxylic Acids Apr. 14 Carboxylic Acid Derivatives Apr. 21 Enols and Enolates Apr. 28 Enols and Enolates Experiment Camphor Reduction Friedel Crafts Alkylation Grignard Triphenylmethanol President’s Day – Dry Lab NMR Workshop Borneol Oxidation Haloform None Reductive Amination Grignard – CO2 Benzocaine Crossed Aldol Patriot’s Day – Dry Lab Presentations/Check-Out Chapter 16 16, 17 17 13 13 15 11 18 -19 20 20 21 22 22 ____________________________________________________________________________________________ *This outline is a tentative schedule. The schedule and the syllabus are subject to change. Changes will be announced in class and/or posted to Blackboard. * A word of advice: The pace of this course moves quickly – so come to class prepared, work diligently, and seek help if you need it. Don’t get behind!