JUNE 2013 Summary of Changes to the Queensland Health List of Approved Medicines (LAM)
as recommended by the Queensland Health Medicines Advisory Committee (QHMAC)
ITEM
#
MEDICINE
DECISION &
DATE
EFFECTIVE
RESTRICTION
13/046
ACETYLCYSTEINE
INJECTION 6g in
30mL (Acetadote®)
ADDED
1-Aug-13
For management of paracetamol overdose.
13/043
METARAMINOL
PREFILLED
SYRINGE 5mg in
10mL
ONDANSETRON
ORAL
DISINTEGRATING
TABLET 4mg
ADDED
1-Aug-13
No restriction
13/T01
ADDED
01-Sept-13
ADDED
01-Sept-13
Specialist Staff for
(a) Patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications;
(b) For use in postoperative nausea and vomiting (PONV) (i) in adult patients not responsive to alternative
oral antiemetic therapy and who cannot use other forms of ondansetron; and (ii) in children;
(c) Use within Emergency Departments for acute gastroenteritis in children up to age sixteen years when
frequent vomiting is interfering with oral rehydration therapy. It is recommended that the Royal Children's
Hospital (Brisbane) Emergency Department Flowchart for Management of Acute Gastroenteritis be
consulted and followed.
Where medicines are used outside their TGA approved indications, patients should be made fully aware of
the status of the medicine and appropriate consent obtained
Specialist Staff for patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications
13/T01
ONDANSETRON
ORAL
DISINTEGRATING
TABLET 8mg
13/050
RIVAROXABAN
TABLET 15mg
ADDED
1-Aug-13
For initial treatment of confirmed acute symptomatic deep vein thrombosis (DVT) without symptomatic
pulmonary embolism (PE).
13/050
RIVAROXABAN
TABLET 20mg
ADDED
1-Aug-13
For continuing treatment (a) of confirmed acute symptomatic deep vein thrombosis (DVT) without
symptomatic pulmonary embolism (PE); and (b) for prevention of recurrent venous thromboembolism (VTE)
ITEM
#
MEDICINE
DECISION &
DATE
EFFECTIVE
RESTRICTION
13/006
SUGAMMADEX
SODIUM
INJECTION 200mg
in 2mL
ADDED
01-Aug-13
For paediatric use by credentialed anaesthetists and Emergency Physicians for emergency reversal of
rocuronium in children who cannot be intubated or cannot be oxygenated. [Only limited stock may be held
outside pharmacy - on the difficult intubation trolley. All other use of sugammadex must be on an individual
patient approval basis, with approval by the Director of Anaesthetics, the Director of Emergency Medicine or
nominated representative, and in line with the SWAPNET guideline. (Available at
http://qheps.health.qld.gov.au/patientflow/docs/swapnet_sugam_guide.pdf)
Specialist Staff and Country Medical Superintendents for the treatment of cardiac glycoside intoxication
resulting in life threatening cardiac arrhythmias; cardiac arrest; cardiac decompensation with hypotension;
serum potassium >5.5mmol/L with cardiovascular instability or compromise. In the absence of these
recognised indications of cardiac glycoside toxicity, digoxin immune Fab is not indicated based solely on a
serum digoxin concentration.
Specialist Staff for patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications
13/018
A2
DIGOXIN IMMUNE
Fab (Ovine) Powder
for injection 40mg
(DigiFab)
AMENDED
01-Aug-13
13/T01
GRANISETRON
INJECTION 3mg in
3mL
AMENDED
01-Sept-13
13/012
A
HUMAN C1
ESTERASE
INHIBITOR Powder
for injection 50unit
per mL, 500unit
AMENDED
01-Aug-13
Immunology physicians or Emergency Department physicians, after consultation with an immunology
physician, for the treatment of patients with previously confirmed hereditary angioedema for:
a) Acute attacks of angioedema affecting the upper respiratory tract or persistent abdominal attack resulting
in significant intestinal obstruction; and
b) Prophylaxis prior to significant dental and surgical procedures or for symptomatic attacks during
pregnancy. (NOTE: Safety in pregnancy has not been established. Use only if indicated).
13/012
ICATIBANT Injection,
single use pre-filled
syringe 30mg in 3mL
AMENDED
01-Aug-13
Immunology physicians or Emergency Department physicians, after consultation with an immunology
physician, for the treatment of patients with previously confirmed hereditary angioedema for:
a) Acute attacks of angioedema affecting the upper respiratory tract or persistent abdominal attack resulting
in significant intestinal obstruction; and
b) For outpatient use as per the PBS indications.
13/T01
ONDANSETRON
INJECTION
4mg in 2mL;
8mg in 4mL
AMENDED
01-Sept-13
Specialist Staff for
(a) Patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications;
(b) Use for postoperative nausea and vomiting (PONV)
Page 2 of 5
ITEM
#
MEDICINE
DECISION &
DATE
EFFECTIVE
RESTRICTION
13/T01
ONDANSETRON
SYRUP 4mg in 5mL
AMENDED
01-Sept-13
Specialist Staff for use in children who cannot use any other forms of ondansetron.
Where medicines are used outside their TGA approved indications, patients should be made fully aware of
the status of the medicine and appropriate consent obtained.
13/T01
ONDANSETRON
TABLET
4mg
AMENDED
01-Sept-13
13/T01
ONDANSETRON
TABLET
8mg
AMENDED
01-Sept-13
Specialist Staff for
(a) Patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications;
(b) For use in postoperative nausea and vomiting (PONV) (i) in adult patients not responsive to alternative
oral antiemetic therapy; and (ii) in children.Where medicines are used outside their TGA approved
indications, patients should be made fully aware of the status of the medicine and appropriate consent
obtained.
Specialist Staff for patients on cytotoxic chemotherapy or radiotherapy as per the PBS indications.
13/028
CINACALCET TAB
30mg, 60mg, 90mg
DEFERRED
13/048
SODIUM CHLORIDE
COMPOUND
(Ringers solution
lactated with
glucose) Powder for
reconstitution –
sachet (4) plus bottle
with paediatric tip
(FLO kids Sinus
Care®)
SODIUM CHLORIDE
COMPOUND (sterile,
isotonic), paediatric
nasal spray,15mL
VITAMIN, FAT
SOLUBLE
COMPOUND IN
DEFERRED
13/049
13/051
DEFERRED
DEFERRED
Page 3 of 5
ITEM
#
13/T03
MEDICINE
TOCOPHEROL PEG
SUSPENSION,
chewable tablet, soft
gel capsule,
paediatric liquid
60mL
ANIDULAFUNGIN
Injection 100mg
DECISION &
DATE
EFFECTIVE
DELETED
01-Sept-13
13/T01
GRANISETRON
INJECTION 1mg in
1mL
DELETED
01-Sept-13
13/044
LEPIRUDIN
INJECTION 50mg
ONDANSETRON
WAFER 4mg;8mg
DELETED
01-Aug-13
DELETED
01-Sept-13
13/T01
13/T02
13/047
13/042
RESTRICTION
SIMVASTATIN
TABLET 80mg
INDACATEROL
CAPSULE,
POWDER FOR
INHALATION,
150microgram,
300microgram
DELETED
01-Sept-13
NOT ADDED
QUETIAPINE
TABLET
200mg;
300mg
NOT ADDED
Page 4 of 5
ITEM
#
MEDICINE
DECISION &
DATE
EFFECTIVE
13/T03
CASPOFUNGIN
INJECTION
50mg;
70mg
NOTED
13/045
FOR INFORMATION
- CATAG SURVEY
NOTED
13/025
TRICLOSAN Skin
Cleanser, Soap 1%
(125g)
NOTED
RESTRICTION
Page 5 of 5