Syllabus for Neuropsychopharmacology (D840900) 2013 2/ 19/ 2013 Course Objectives: (1) To become familiar with the basic principles and techniques associated with neuropharmacological studies. (2) To learn how neuropharmacological manipulation of transmitter systems can be used to (a) gain insight into the normal functioning of transmitter systems and (b) alter transmitter activity for therapeutic purposes, especially in psychiatric disorders such as substance abuse, mood disorders, and schizophrenia as well as neurodegeneration. Textbooks: (1) E. J. Nestler, S. E. Hyman & R. C. Malenka (2009). Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2nd Ed.), McGraw-Hill Companies, Inc.; (2) R. S. Feldman, J. S. Meyer, L. F. Quenzer (1997). Principles of Neuropsychopharmacology (1st Ed.), Sinauer Associates, Inc.; (3) S. M. Stahl (2008): Stahl’s Essential Psychopharmacology (3rd Ed.), Cambridge Medicine. Time: Tuesday 9:10 AM ~12:00 PM (3 credits) Classroom: 成大力行校區社科院大樓 80209 教室 Instructors: 成大心理學系胡書榕老師 (shujungh@mail.ncku.edu.tw; 275-7575 ext. 56515) 和陳德祐老師 (chendy@mail.ncku.edu.tw; 275-7575 ext. 56517) Teaching Assistant: TBA Grading: Midterm exam (40%); Final exam (40%); A 10-page written report of literature review related to our class topics, which need to be approved by 陳德祐老師 (20%) Week Date Lecture Contents Reading Lecturer 1 2/19 Organization & Introduction The syllabus; (2) Ch1 胡書榕 Principles of Pharmacology I 3 2/26 Principles of Pharmacology II (1) Ch1, (3) Ch4, 5 胡書榕 4 3/5 Methods in Neuropsychopharmacology (2) Ch2 胡書榕 5 3/12 Neurons & Glial Cells (2) Ch3; (3) Ch1 胡書榕 6 3/19 Functional Neuroanatomy (2) Ch4; (3) Ch2 陳德祐 7 3/26 Cellular Basis of Communication & Synapses (1) Ch2, 3, 4; (2) Ch6; 陳德祐 & Signaling Pathways (3) Ch3 8 4/2 Spring Break 9 4/9 Acetylcholine (2) Ch7 胡書榕 10 4/16 Catecholamines & Indolamines (2) Ch8, 9 胡書榕 11 4/23 Midterm Exam 2/19 ~ 4/16 授課內容 胡書榕 12 4/30 Excitatory and Inhibitory Amino Acids (1) Ch5; (2) Ch10 陳德祐 13 5/7 Neuropeptides and Atypical Neurotransmitters (1) Ch7, 8; (2) Ch11 陳德祐 14 5/14 Substance Abuse I: Amphetamine, Cocaine, (2) Ch13, 14, 15; (3) 陳德祐 Nicotine, Caffeine, and Alcohol Ch19 Substance Abuse II: Opiates & Marijuana and (2) Ch12 & additional Their Roles in Treating Pain readings Parkinson’s & Alzheimer’s Disease (1) Ch17; (2) Ch20; (3) 15 16 5/21 5/28 胡書榕 陳德祐 18 17 6/4 Schizophrenia & Mood Disorders (1) Ch14, 16; (2) Ch18, 陳德祐 19; (3) Ch9, 11, 12 18 6/11 Final Exam 19 6/18 Written Report Due 4/30 ~ 6/4 授課內容 陳德祐 陳德祐