A. ORIGINAL REPORTS:
1.
Makrigiorgos GM and Waker AJ. The measurement of dose and dose equivalent levels for in vivo neutron activation analysis. Phys Med Biol 1985; 30:909-919.
2.
Makrigiorgos GM and Waker AJ. On a modification of Lea's theory for initial recombination of ions. Int J Appl Radiat Isot 1985; 36:509-510.
3.
Makrigiorgos GM and Waker AJ. Initial recombination of ions in electron tracks: an experimental evaluation of Lea's model and a modified track structure model. Int
J Appl Radiat Isot 1985; 36:813-818.
4.
Makrigiorgos GM and Waker AJ. Measurement of the restricted dose mean LET ratios of two x-ray spectra on the basis of initial recombination theory. Radiat Prot
Dosim 1985; 13:383-386.
5.
Makrigiorgos GM and Waker AJ. The measurement of the restricted LET of photon sources (5 keV-1.2 MeV) with the recombination method: Theory and practice. Phys
Med Biol 1986; 31:543-554.
6.
Makrigiorgos GM . A novel application of high-pressure ionization chambers to measure the mean neutron energy or the gamma ray dose fraction of a neutron-gamma radiation field ( part I, theory ).
Phys Med Biol 1986; 31:1315-1326.
7.
Makrigiorgos GM and Waker AJ. A high-pressure ionization chamber to measure the mean neutron energy or the gamma ray dose fraction of a neutron-gamma radiation field ( part II, experiment ). Phys Med Biol 1986; 31:1327-1338.
8.
Makrigiorgos GM.
Potential of a gel-walled recombination chamber for high energy neutron dosimetry. Nucl Instrum Meth 1987; A265: 605-609.
9.
Makrigiorgos GM.
Characteristics of an ethylene-polyethylene high-pressure ionization chamber and derivation of radiation dose and quality information in mixed beam radiation fields. Med Phys 1988; 15:36-40.
10.
Makrigiorgos GM.
Calculation of the restricted dose mean LET of Auger electron emitters. Int J Radiat Appl Instrum Part A 1987; 38:407-408.
11.
Makrigiorgos GM and Antonadou D. The measurement of the restricted dose mean
LET outside the primary beam of a Co-60 radiotherapy unit Radiat Res 1987;
110:142-148.

12.
Lymberis C, Makrigiorgos GM , Sbonias V, Polizois N, Mortzos G, Bakas T and
Fountos G. Radiocesium levels in human muscle samples in Greece one year after the Chernobyl accident. Int J Radiat Appl Instrum Part A , 1988; 39:175-176.
13.
Makrigiorgos GM Derivation of average radiation quality parameters in neutron-gamma radiation fields with a tissue equivalent high-pressure ionization chamber: theory and practice. Radiat Res 1989; 118:387-400.
14.
Makrigiorgos GM , Waker AJ, Kassis AI, and Adelstein SJ. Use of a high-pressure ionization chamber: a comparison with tissue equivalent proportional counters for obtaining microdosimetric information from unspecified radiation fields. Radiat Prot
Dosim 1989; 29: 15-19.
15.
Makrigiorgos GM , Antonadou D, Proukakis C and Throuvalas N. Measurement of the restricted LET of stray radiation close to the treatment volume of 12 and 18 MV clinical photon beams.
Med Phys 1989; 16:302-304.
16.
Folkard M, Makrigiorgos GM , Roper M and Michael B. Measurements of neutron energy using a recoil proton telescope and a high-pressure ionization chamber.
Radiat Res 1989; 118:37-45.
17.
Makrigiorgos GM , Kassis AI, Baranowska-Kortylewicz J, McElvany KD., Welch
MJ., Sastry KSR. and Adelstein SJ. Radiotoxicity of
123
IUdR in V79 cells : A comparison to
125
IUdR.
Radiat Re s 1989; 118:532-544.
18.
Makrigiorgos GM , Adelstein SJ and Kassis AI. Limitations of conventional internal dosimetry at the cellular level.
J Nucl Med 1989; 30:1856-1862.
19.
Makrigiorgos GM , Antonadou D, Proukakis C, Throuvalas N, Michael BD, Folkard
M and Roper M. Restricted LET investigations around high-energy electron beams.
Phys Med Biol 1990; 35: 139-145.
20.
Makrigiorgos GM , Smathers JB, Myers L.T and Benedict S.H Radiation quality investigations around a neutron therapy beam using a high-pressure ionization chamber. Med Phys 1990; 17:84-86.
21.
Kassis AI, Makrigiorgos GM and Adelstein SJ. Implications of radiobiological and dosimetric studies of DNA-incorporated
123
I: The use of Auger effects as a biological probe at the nanometer level. Radiat Prot Dosim 1990; 31:333-338.
22.
Makrigiorgos GM , Ito S, Baranowska-Kortylewicz, Vinter DW, Iqbal A, Van den
Abbeele AD, Adelstein SJ, and Kassis AI. Inhomogeneous deposition of radiopharmaceuticals at the cellular level: Experimental evidence and dosimetric implications. J Nucl Med 1990; 31:1358-1363.

23.
Makrigiorgos GM , Adelstein SJ, and Kassis AI. Cellular dosimetry estimates for
99m
Tc-labeled microspheres and macroaggregates in humans. J Amer Med Assoc,
JAMA 1990; 264:592-595.
24.
Makrigiorgos GM , Kortylewicz JB, Vinter DW, Iqbal A, Van den Abbeele AD,
Adelstein SJ, and Kassis AI. Microscopic spatial inhomogeneity of radiopharmaceutical deposition in mammalian tissues: Dosimetry at the cellular level and comparison with conventional dosimetry. Radiat Prot Dosim 1990; 31:319-324.
25.
Baranowska-Kortylewicz J, Makrigiorgos GM , Van Den Abbeele AD, Berman RM,
Adelstein SJ and Kassis AI.
123
IUdR in the radiotherapy of an early ascites tumor model. Int J Radiat Oncol Biol Phys 1991; 21:1541-1551.
26.
Makrigiorgos GM and Chin LM. Measurement of the restricted LET of orthovoltage and low energy x-rays in tissue equivalent plastic.
Phys Med Biol 1991; 36:835-841.
27.
Makrigiorgos GM , Berman RM, Baranowska-Kortylewicz J, Bump E, Humm JL,
Adelstein SJ and Kassis AI. DNA damage produced in V79 cells by
DNA-incorporated
123
IUdR: A comparison to
125
IUdR. Radiat Res 1992; 309-314.
28.
Makrigiorgos GM , Baranowska-Kortylewicz J, Bump E, Sahu SK, Berman RM and
Kassis AI. A method for detection of hydroxyl free radicals in the vicinity of biomolecules using radiation-induced fluorescence of coumarin. Int J Radiat Biol
1993; 63, 445-458.
29.
Makrigiorgos GM , Folkard M, Huang C, Bump E, Baranowska-Kortylewicz J,
Sahu SK, Michael BD and Kassis AI. Quantification of radiation-induced hydroxyl radicals within nucleohistones using a molecular fluorescent probe.
Radiat Res 1994;
138, 177-185.
30.
Collins A, Makrigiorgos GM and Svensson G. Coumarin chemical dosimeter for radiation therapy. Med Phys 1994; 21, 1741-1747.
31.
Sahu SK, Kassis AI, Makrigiorgos GM , Baranowska-Kortylewicz J and Adelstein
SJ. The effects of
111
Indium decay on pBr322 DNA. Radiat Res 1994; 141, 193-198.
32.
Makrigiorgos GM , Bump E, Huang C, and Kassis AI. The accessibility of nucleic acid-complexed biomolecules to hydroxyl radicals correlates with their conformation:
A fluorescence polarization study. Int J Radiat Biol 1994; 66:247-256.
33.
Makrigiorgos GM , Bump E, Huang C, and Kassis AI. A fluorimetric method for the detection of copper-mediated hydroxyl-free radicals in the vicinity of DNA. Free
Radical Biol Med 1995; 18: 669-678.
34.
Chakrabarti S, Makrigiorgos GM , O'Brien K, Bump E, Kassis AI. Measurement of hydroxyl radicals generated in the vicinity of DNA by bleomycin-iron complexes.

Free Radical Biol Med 1996; 20: 777-783.
35.
Chakrabarti S, Mahmood A, Kassis AI, Bump E, Jones A and Makrigiorgos GM .
Generation of hydroxyl radicals by nucleohistone-bound metal-adriamycin complexes. Free Radical Research 1996; 25: 207-220.
36.
Makrigiorgos GM , Kassis AI, Mahmood A, Bump EA and Savvides P. Novel fluorescein-based flow-cytometric method for detection of lipid peroxidation on individual cells. Free Radical Biol Med 1997; 22:93-100.
37.
Makrigiorgos GM . Detection of lipid peroxidation on erythrocytes using the excimer-forming property of a lipophilic BODIPY fluorescent dye. J Biochem
Biophys Meth 1997; 35:23-35.
38.
Chakrabarti S, Slayter H, Kassis AI, Bump E, Sahu SK and Makrigiorgos GM .
Continuous detection of radiation- or metal- generated hydroxyl radicals within nucleosomes. Int J Radiat Biol 1998; 73:53-63.
39.
Kassis AI, Wen PY, Van den Abbeele AD, Kortylewicz JB, Makrigiorgos GM ,
Metz KR, Matalka KC, Sahu SK, Black PMcL and Adelstein SJ. 5-
125
iododeoxyuridine in the radiotherapy of brain tumors in rats. J Nucl Med, 1998;
39:1148-1154.
40.
Botchway SW, Chakrabarti S and Makrigiorgos GM.
Novel Visible And Ultraviolet
Light Photogeneration of Hydroxyl Radicals By 2-Methyl-4-Nitro-quinoline-N-Oxide
(MNO) and 4,4’-Dinitro-(2,2’) Bipyridinyl-N,N’-Dioxide (DBD).
Photochem
Photobiol, 1998; 67:635-640.
41.
Makrigiorgos GM , Chakrabarti S and Mahmood A. Fluorescent labeling of abasic sites: Design of a novel methodology to detect closely-spaced damage sites in DNA.
Int J Radiat Biol , 1998; 74:99-109.
42.
Maulik G, Savvides P, Kassis AI and Makrigiorgos GM.
Fluoresceinated phosphoethanolamine as a non-exchangable probe for flow-cytometric measurement of lipid peroxidation: application to erythrocytes from vitamin-E deficient rats. Free
Radical Biol Med, 1998; 25:645-653.
43.
Chakrabarti, S, Mahmood, A, and Makrigiorgos, GM. Fluorescent labeling of closely-spaced aldehydes induced by bleomycin-Fe(III) in DNA. Int J Radiat Biol ,
1999; 75:1055-1065.
44.
Maulik G, Botchway S, Chakrabarti S, Tetradis S, Price B and Makrigiorgos GM
Novel non-isotopic detection of MutY-recognized mismatches in DNA via ultrasensitive detection of aldehydes. Nucleic Acids Research , 1999; 27:1316-132.
45.
Chakrabarti S, Price B, Tetradis S, Fox EA, Zhang Y, Maulik G, and Makrigiorgos

GM . Highly selective isolation of unknown mutations in diverse DNA fragments:
Towards new multiplex screening in cancer. Cancer Research , 2000; 60:3732-
3737.
46.
Zhang Y, Price B, Tetradis S, Chakrabarti S, Maulik G and Makrigiorgos GM .
Reproducible and inexpensive probe preparation for oligonucleotide microarrays .
Nucleic Acids Research , 2001, 29: e66.
47.
Kaur M, Zhang Y, Liu W, Tetradis S, Price B, and Makrigiorgos GM . Ligation of a primer at the mutation: a method to detect low level mutations in DNA.
Mutagenesis , 2002, 17:365-374.
48.
Zhang Y, Kaur M, Tetradis S, Price B and Makrigiorgos GM . An amplification and ligation-based method to scan for unknown mutations in DNA. Human Mutation ,
2002, 20:139-147.
49.
Xue LY, Butler NJ, Makrigiorgos GM , Adelstein SJ and Kassis AI. Bystander
Effect Produced by Radiolabeled Tumor Cells In Vivo . Proceedings of the National
Academy of Sciences of the USA, 2002, 99: 13765-13770.
50.
Makrigiorgos GM ( Corresponding author ), Chakrabarti S, Zhang Y and Price B. PCRbased amplification method retaining the quantitative difference between two complex genomes. Nature Biotechnology , 2002, 20:936-939. (Highlighted in the
‘ In this Issue’
section of the Journal).
51.
Liu W, Kaur M and Makrigiorgos GM. Detection of hotspot mutations and polymorphisms using an enhanced PCR-RFLP approach. Human Mutation 2003
21: 535-541.
52.
Kaur M and Makrigiorgos GM . Novel amplification of DNA in a hairpin structure: towards a radical elimination of PCR errors from amplified DNA. Nucleic Acids
Research 2003, 31: e26.
53.
Liu W and Makrigiorgos GM . Sensitive and quantitative detection of mutations associated with clinical resistance to STI-571. Leukemia Research 2003, 27:979-
982.
54.
Liu W, Kaur M, Wang G, Zhu P, Zhang Y and Makrigiorgos GM . Inverse PCRbased RFLP scanning identifies low-level mutation signatures in human cells and tumors. Cancer Research , 2004, 64, 2544-2551
55.
Wang G, Brennan C, Rook M, Wolfe J, Leo C, Chin L, Pan H, Liu W, Price B, and
Makrigiorgos GM . Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples. Nucleic Acids Research ,
2004; 32:e76.

56.
Chen S, Wang G, Makrigiorgos GM , and Price BP. Stable RNAi-mediated silencing of ATM alters the transcriptional profile of HeLa cells. Biochem Biophys Research
Commun , 2004; 317:1037-44.
57.
Wang G, Maher E, Brennan C, Leo C, Chin L, Rook M, Wolfe J, Kaur M, Zhu P and
Makrigiorgos GM. DNA amplification method tolerant to sample degradation.
Genome Research , 2004; 14: 2357-2366.
58.
Wang F, Kaur M, Liu W, Zhu P, Li J, Wang L and Makrigiorgos GM . High throughput scanning of breast tumor surgical specimens for low-level mutations.
Clinical Chemistry and Laboratory Medicine , 2005; 43:810-816.
59.
Li J, Harris L, Mamon H, Kulke M, Liu W, Zhu P and Makrigiorgos GM . Whole genome amplification of plasma-circulating DNA enables expanded screening for allelic imbalance in plasma. Journal of Molecular Diagnostics , 2006; 8:22-30.
60.
Li J, Wang F, Mamon H, Kulke M, Harris L, Maher E, Wang L and Makrigiorgos
GM .
Anti-primer quenching-based real time PCR and its application to the analysis of clinical cancer samples. Clinical Chemistry, 2006; 52:624-633.
61.
Ogino S, Kawasaki T, Brahmandam M, Cantor M, Namgyal C, Kirkner G,
Spiegelman D, Makrigiorgos GM , Weisenberger DJ, Laird PW, Loda M, and Fuchs
SH. Precision and Performance Characteristics of Sodium Bisulfite Conversion and
Quantitative Real-Time PCR (MethyLight) for DNA Methylation Analysis on
Paraffin Embedded Tissue. Journal of Molecular Diagnostics , 2006; 8, 209-217.
62.
Park M, Moore S, Limpa-Amara N, Kang Z and Makrigiorgos GM . Performance of a coumarin based liquid dosimeter for phantom evaluations of internal dosimetry.
Nuclear Instruments and Methods in Physics Research A, 2006; 569:543-547.
63.
Kanaklata R, Wang L, Makrigiorgos GM , and Price BP. Methylation of the ATM promoter in human glioma cells alters sensitivity to ionizing radiation. Biochem
Biophys Research Commun , 2006; 344: 821-826.
64.
Amicarelli G, Adlerstein D, Shehi E, Wang F, and Makrigiorgos GM .
Genotypespecific signal generation based on digestion of 3-way DNA junctions: application to
K-ras mutation detection. Clinical Chemistry , 2006; 52: 1855-1863.
65.
Hong F. Xiang, Jun S. Song, Roy B. Tishler, Makrigiorgos GM ,
Lee M. Chin,
Laurence E. Court. Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations.
Medical Physics , 2007; 34:1266-1273
66.
Wang F, Wang L, Briggs C, Sicinska E, Gaston S, Mamon H, Kulke M, Zamponi R,
Loda M, Maher E, Ogino S, Fuchs C, Li J, Hader C, Makrigiorgos GM . DNA degradation test predicts downstream PCR success in whole-genome amplified DNA

from diverse clinical samples. Journal of Molecular Diagnostics , 2007; 9: 441-451.
67.
Li J, Berbeco R, Distel RJ, Jänne PA, Wang L and Makrigiorgos GM .
s-RT-MELT for rapid mutation scanning using enzymatic selection and real time DNA-melting:
New potential for multiplex genetic screening. Nucleic Acids Research 2007; e84:
1-11.
68.
Amicarelli G, Shehi E, Makrigiorgos GM and Adlerstein D. FLAG Assay as a
Novel Method for Real Time Signal Generation during PCR: Application to
Detection and Genotyping of KRAS Codon 12 Mutations. Nucleic Acids Research ,
2007; e131:1-9.
69.
Bonnano C, Shehi E, Adlerstein D and Makrigiorgos GM . MS-FLAG, a novel realtime signal generation method for Methylation-Specific PCR. Clinical Chemistry ,
2007; 53: 2119-2127.
70.
Park M, Mahmood A, Zimmerman RE, Limpa-Amara N, Makrigiorgos GM , and
Moore S. Effects of adsorption of metal radionuclides on plastic phantoms used for dosimetry validation in radioimmunotherapy. Medical Physics , 2008; 35:1606-1610.
71.
Court LE, Tishler RB, Allen A, Xiang H, Makrigiorgos GM , Chin L, Experimental evaluation of the accuracy of skin dose calculation for a commercial treatment planning system. J. Appl. Clin. Med. Phys . 2008; 9: 2792-2796
72.
Li J, Wang L, Mamon H, Kulke M, Berbeco R, and Makrigiorgos GM. Replacing
PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nature Medicine, 2008; 14: pp579 – 584.
73.
Mamon H, Hader C, Li J, Wang L, Kulke M, Amicarelli G, Shehi E, Adlerstein D,
Roper K, Killion L, Hooshmand S and Makrigiorgos GM. Preferential amplification of apoptotic DNA from plasma: potential for enhancing detection of minor DNA alterations in circulating DNA. Clinical Chemistry , 2008; 54: 1582-1584
74.
Chin D, Treister N, Friedland B, Cormack R, Tichler R, Makrigiorgos GM and
Court L. Effect of dental restoration and prosthesis on radiotherapy dose distributions: a Monte Carlo study. J. Appl. Clin. Med. Phys . 2009; 10:2853
75.
Li J, Wang L, Jänne P, and
Makrigiorgos GM . COLD-PCR increases the mutationdetection selectivity of Taqman-based real time PCR. Clinical Chemistry , 2009; 55:
748-756.
76.
Kuang Y, Rogers A, Wang L, Makrigiorgos GM , Vetrand K, Thiede S, Distel R and Jänne P. Non-Invasive Detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer. Clinical Cancer Research , 2009; 15:2630-6.
77.
Lang JE, Magbanua M, Scott J, Makrigiorgos GM , Wang G, Federman S, Esserman

LJ, Park J and Haqq C. A Comparison of RNA Amplification Techniques at Subnanogram Input Concentration. BMC Genomics , 2009; 10:326-330
78.
Cormack R, Sridhar S, Suh W, D’Amico A and
Makrigiorgos GM . Biological In-
Situ dose-painting for image-guided radiation therapy using drug-loaded implantable devices. International Journal for Radiation Oncology, Biology and Physics ,
2010; 76; 615-623
(The IJROBP editors selected this article to be highlighted in the same journal issue in the Issue Highlights section, which summarizes 4 of the 45 contributions published; additionally the article was highlighted in the online services , Uro-today; and GenomeWeb daily news )
79.
Li J, Milbury C, Li C and Makrigiorgos GM . Two round COLD-PCR–based Sanger sequencing identifies novel mutations in lung adenocarcinoma. Human Mutation ,
2009; 11:1583-1590.
(The Editors selected this article for the Highlights section of this issue: Selective Amplification of Mutant
DNA: Mutations Come to Light in Melting DNA, Ulf Landegren , Human Mutation 2009, In This Issue , HuMu
21140).
80.
Milbury C, Li J and Makrigiorgos GM . COLD-PCR-enhanced high-resolution melting enables rapid and selective identification of low-level unknown mutations.
Clinical Chemistry , 2009; 55:2130-2143.
(The Editors selected this article for a full-page Editorial in the same journal issue: COLD-PCR Finds Hot
Application in Mutation Analysis . R Luthra and Z. Zuo, Clinical Chemistry 2009; 55:20772078).
81.
Court LEC, Urribarri J, and Makrigiorgos GM . Carbon fiber couches and skin sparing. J. Appl. Clin. Med. Phys . 2010; 11:3241
82.
Zerilli F, Bonanno C, Shehi E, Amicarelli G, Adlerstein and Makrigiorgos GM .
MS-LAMP, a novel isothermal method for the detection of hypermethylated DNA in simplex and multiplex formats. Clinical Chemistry , 2010; 56:1287-1296
83.
Zhu X, Palmer M, Makrigiorgos GM , and Kassis AI. Solid-Tumor Radionuclide
Therapy Dosimetry: New Paradigms in View of Tumor Micro-environment and
Angiogenesis. Medical Physics , 2010; 37:2974-84
84.
Tada, DB, Singh S, Nagesha D, Jost E, O’Levy C, Gultepe E, Cormack C,
Makrigiorgos GM , and Sridhar S. Chitosan film containing PLGA nanoparticles: a platform for localized dual- drug release. Pharmaceutical Research , 2010; 27:1738-
45.
85.
Nagesha1a D, Tada DB, Stambaugh1 CKK , Jost E, Levy C, Cormack R,
Makrigiorgos GM , Sridhar S. Drug-eluting nanoporous coatings on gold fiducials for Biological In-Situ Image-Guided Radio-Therapy. Physics in Medicine and
Biology , 2010; 55:6039-52.
86.
Song C, Milbury C, Li J, Liu P, Zhao M and Makrigiorgos GM . Rapid and sensitive detection of KRAS mutation after COLD-PCR enrichment and high resolution melting analysis. Diagnostic Molecular Pathology , 2011; 20: 81-9

87.
Milbury CA, Chen C, Mamon H, Liu P, Santagata S, and Makrigiorgos GM .
Multiplex amplification coupled with COLD-PCR and High Resolution Melting enable identification of low-abundance mutations in cancer samples with low DNA content. Journal of Molecular Diagnostics , 2011; 13: 220-232.
88.
Ngwa W, Makrigiorgos GM and Berbeco R. Applying gold nanoparticles as tumorvascular disrupting agents during brachytherapy: Estimation of endothelial dose enhancement. Physics in Medicine and Biology , 2010: 55: 6533-6548.
89.
Galbiati S, Brisci A, Lalatta F, Seia M, Makrigiorgos GM , Ferrari M, and
Cremonesi L. Full COLD-PCR protocol for noninvasive prenatal diagnosis of genetic diseases. Clinical Chemistry , 2011; 57: 136-138.
90.
Milbury CA, Li, J and Makrigiorgos GM. ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations.
Nucleic Acids Research , 2011; 39, e2
91.
Berbeco R, Ngwa W and Makrigiorgos GM . Localized dose enhancement to tumor blood vessel endothelial cells via megavoltage x-rays and targeted gold nanoparticles: new potential for external beam radiotherapy. International Journal for Radiation
Oncology, Biology and Physics, 2011; 81:270-276.
92.
Li J, Janne P and Makrigiorgos GM.
Biotinylated probe isolation of targeted gene region improves detection of T790M EGFR mutation via PNA-enriched real-time
PCR. Clinical Chemistry , 2011; 57:770-3.
93.
Tsiamas P, Seco J, Han Z, Bhagwat M, Lyatskaya L, Maddox J, Kappas C,
Theodorou K, M. Makrigiorgos GM , Marcus K, and Zygmanski P. A modification of Flattening Filter Free linac for IMRT. Med Phys . 2011; 38:2342-2352
94.
Ngwa W, Korideck H, Chin LM, Makrigiorgos GM , and Berbeco RI. MOSFET assessment of radiation dose delivered to mice using the Small Animal Radiation
Research Platform (SARRP). Radiat Res . 2011; 76:816-20
95.
Milbury CA, Correll M, Quackenbush J, Rubio R, and Makrigiorgos GM . COLD-
PCR enrichment of rare mutations prior to targeted amplicon re-sequencing. Clinical
Chemistry , 2012; 58:580-9
96.
Ngwa W, Makrigiorgos GM and Berbeco IR. Gold nanoparticle-aided
Brachytherapy with vascular dose painting: Estimation of dose enhancement to the tumor endothelial cell nucleus. Med. Phys . 2012; 39:392-398
97.
Castellanos-Rizaldos, Liu P, Milbury CA, Guha M, Brisci A, Cremonesi L, Ferrari
M, Mamon H, and Makrigiorgos GM . Temperature-Tolerant COLD-PCR eliminates temperature stringency and enables robust mutation enrichment Clinical
Chemistry , 2012; 58:1130-1138.

98.
Tsiamas P, Sajo E, Cifter F, Theodorou K, Kappas K, Makrigiorgos GM , Marcus
K, Zygmanski P. Optimal Clinical Megavoltage X-Ray Beam Quality for Contrast
Enhanced RT (CERT). Med Phys 2012; 39:3710-3710
99.
Berbeco RI, Korideck H, Ngwa W, Kumar R, Patel J, Sridhar S, Johnson S, Price B,
Kimmelman A and Makrigiorgos GM . DNA damage enhancement for gold nanoparticles from clinical MV energy beams. Radiat Res . 2012;178:604-8
100.
Ngwa W, Makrigiorgos GM , and Berbeco RI. Enhancing Stereotactic Radiosurgery for Neovascular Age-Related Macular Degeneration, Using Gold Nanoparticles. Med
Phys. 2012; 39: 3798-3798
101.
Ngwa W, Korideck H, Kassis AI, Kumar R, Sridhar, S, Makrigiorgos GM ,
Cormack RA. In vitro radiosensitization by gold nanoparticles during continuous low dose rate gamma irradiation with I-125 brachytherapy seeds. Nanomedicine (NBM) ,
2013; 9:25-7.
102.
Guha M, Castellanos-Rizaldos E, Liu P, Mamon H and Makrigiorgos GM .
Differential strand separation at critical temperature: a minimally disruptive enrichment method for low-abundance unknown DNA mutations. Nucleic Acid Res
2013 : e50
( This article was selected as a Featured Article for the Journal, representing the top 5% of articles published in
NAR )
103.
Castellanos-Rizaldos E, Milbury C, and Makrigiorgos GM. Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion. PLoS One 2012; 7: e51362
104.
Zygmanski P, Hoegele W. Tsiamas P, Cilfter F, Ngwa W, Berbeco R, Makrigiorgos
GM and Sajo E. A stochastic model of cell survival for high-Z nanoparticle radiotherapy. Medical Physics Med Phys. 2013; 40: 024102
105.
Kumar R, Korideck H, Ngwa W, Berbeco R, Makrigiorgos GM and Sridhar S.
Facile Synthesis of PEGylated PLGA Nanoparticles Encapsulating Doxorubicin and its In Vitro Evaluation as Potent Drug Delivery Vehicle for Drug Delivery and
Translational Research. Drug Delivery and Translational Research , 2013; 3: 299-
308
106.
Tsiamas P, Cifter F, Ngwa W, Berbeco RI, Kappas C, Theodorou K, Marcus K,
Makrigiorgos GM , Sajo E and Zygmanski P. Impact of beam quality on megavoltage radiotherapy treatment techniques utilizing gold nanoparticles for dose enhancement. Phys Med Biol , 2013; 58: 451-464.
107.
Detappe A, Tsiamas P, Ngwas W, Zygmanski P, Makrigiorgos GM and Berbeco R.
The effect of flattening filter free delivery on endothelial dose enhancement with gold nanoparticles. Med. Phys . 2013; 40: 031706 – Selected for ‘Editor’s Pick’ section.

108.
Tsiamas P, Erno S, Cifter F, Theodorou K, Kappas C, Makrigiorgos GM , Marcus K, and Zygmanski P. Beam quality and dose pertubation of 6MV flattening-filter-free linac. Physica Medica: European Journal for Medical Physics, 2013; S1120-1797
(13) 00026-4
109.
Murphy DM, Bejar R, Stevenson K, Neuberg D, Shi Y, Cubrich C, Richardson K,
Eastlake P, Garcia-Manero G, Kantarjian H, Ebert BL and Makrigiorgos GM . NRAS
Mutations with Low Allele Burden have Independent Prognostic Significance for
Patients with Lower Risk Myelodysplastic Syndromes. Leukemia 2013; 27, 2077–
2081
110.
Castellanos-Rizaldos E, Guha M, and Makrigiorgos GM . DISSECT – method using
PNA-LNA clamp improves detection of EGFR T790M mutation. PLoS One 2013; 6: e67782
111.
Kumar R, Korideck H, Ngwa W, Berbeco RI, Makrigiorgos GM , Sridhar S. Third generation gold nanoplatform optimized for radiation therapy. Transl Cancer Res
2013; 2: doi:10.3978/j.issn.2218-676X.2013.07.02
112.
Castellanos-Rizaldos E, Milbury CA, Karatza E, Chen CC, Makrigiorgos GM and
Merewood A. COLD-PCR amplification of bisulfite-converted DNA allows the enrichment and sequencing of rare un-methylated genomic regions. PLoS One 2014;
9: e94103
113.
Sb ML, Korideck H, Makrigiorgos GM, Tillement O, Berbeco R. Radiation dose enhancement of Gadolinium based AguIx nanoparticles on HeLa cells.
Nanomedicine 2014; pii: 14: S1549-9634
114.
Murphy DM, Castellanos-Rizaldos E, and Makrigiorgos GM Enriching Mutant
Sequences by Modulating the Denaturation Time during PCR. Clinical Chemistry
2014; 60:1014-6.
115.
Castellanos-Rizaldos E, Richardson K, Lin R and Makrigiorgos, GM . Single tube, highly parallel mutation enrichment in cancer gene panels using temperature-tolerant
COLD-PCR. Clinical Chemistry 2015; 61:267-77
116.
Sinha N, Cifter G, Sajo E, Kumar R, Sridhar S, Nguyen P, Cormack RA,
Makrigiorgos GM , and Ngwa W. Brachytherapy Application with in situ Dose-painting
Administered via Gold-nanoparticle Eluters. International Journal for Radiation
Oncology, Biology and Physics , 2014 Dec 5 epub ahead of print
117.
Ngwa W, Sajo E, Ngoma T, Bortfeld T, Gierga D, Burns White K, Akinwande B,
Enwerem-Bromson M, Forbang RT, Winningham TA, Court LE, Odedina FT, Wu R,
Makrigiorgos GM, Nguyen P. T he Potential for Information and Communication
Technologies to catalyze Global collaborations in Radiation Oncology.
International
Journal for Radiation Oncology, Biology and Physics , in Press.

118.
Kumar R, Belz J, Nedre M, Marcovic, S, Cormack RC, Makrigiorgos GM, and Sridhar S.
Nanoparticle based ‘smart’ brachytherapy spacers for delivery of localized combined chemoradiation therapy.
Physics , in Press.
International Journal for Radiation Oncology, Biology and
119.
Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG,
Kozono D, Mak RH, Makrigiorgos GM , Kimmelman AC and Wong K. Novel image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nature
Communications , In Press.
120.
Altundal Y, Cifter G, Sajo E, Panagiotis T, Zygmanski P, Berbeco R, Cormack RA,
Makrigiorgos GM , and Ngwa W. New Potential for enhancing concomitant chemoradiotherapy with FDA approved concentrations of cisplatin via photoelectric mechanism.
Phys Med. 2015; 31:25-30.
B. REFEREED REVIEWS IN JOURNALS
1.
Makrigiorgos GM , Kassis AI, Adelstein SJ. Auger electron emitters: Status, dosimetry, mechanisms and future possibilities. Radiat Environ Biophys 1990; 29: 75-91.
2.
Maulik G, Salgia R and Makrigiorgos GM . Flow-cytometric determination of lipid peroxidation by using fluoresceinated phosphoethanolamines. Methods in Enzymology ,
2002; 352: 82-91.
3.
Makrigiorgos GM . PCR-based detection of minority point mutations. Human
Mutation , 2004; 23, 406-412.
4.
J. Li and Makrigiorgos GM . Anti-primer quenching-based real time PCR for simplex or multiplex DNA quantification and genotyping. Nature Protocols , 2007; 2: 50-58.
5.
C. Milbury, J. Li and Makrigiorgos GM . PCR-based methods for the enrichment of minority alleles and mutations. Clinical Chemistry , 2009; 55: 632-640.
6.
J. Li and Makrigiorgos GM.
s-RT-MELT, a novel technology for mutation screening.
Methods Mol Biol . 2010; 653:207-19
7.
Li J and Makrigiorgos GM . COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing. Biochemical Society Transactions , 2009;
37:427-32.
8.
C. Milbury, J. Li, Pingfang Liu and Makrigiorgos GM.
Cold-PCR: improving the sensitivity of molecular diagnostics assays. Expert Opinion in Molecular Diagnostics ,
2011;11:159-69.
9.
Ngwa N, Kumar R, Sridhar S, Korideck H, Zygmanski P, Cormack RA, Berbeco R &
Makrigiorgos GM . Targeted radiotherapy with gold nanoparticles: current status and future perspectives. Nanomedicine , In Press.

C. REFEREED PROCEEDINGS OF MEETINGS
1. Waker AJ and Makrigiorgos GM.
Radiation quality analysis of a clinical in-vivo neutron activation facility. Proceedings of the 8th Symposium of Microdosimetry ,
Julish, Germany 1982 pp 907-917.
2.
Makrigiorgos GM , Kassis AI and Adelstein SJ. Limitations of MIRD. (Invited paper),
Proceedings of Joint Symposium on Dosimetry of Administered Radionuclides,
ACNP/SNM ' Frontiers in Nuclear Medicine , Washington D.C., 1989; pp 44-57.
3.
Kassis AI, Makrigiorgos GM and Adelstein SJ. Dosimetry of Auger electron emitters;
Proceedings of Joint Symposium on Dosimetry of Administered Radionuclides,
ACNP/SNM ' Frontiers in Nuclear Medicine , Washington D.C., 1989; pp 257-274.
4.
Makrigiorgos GM , Waker AJ and Kassis AI. Microdosimetric characterization of radiation fields with a high-pressure ionization chamber: a comparison with the low pressure proportional counter. Radiat Prot Dosim 1990; 31:161-165.
5.
Makrigiorgos GM , Bump E and Kassis AI. Molecular dosimetry of radiation-induced free radicals using a chromatin-incorporated fluorescent molecule. Published in
Proceedings of the 1st Mediterranean Congress on Radiation Protection, Athens,
Greece, April 5-7, 1994. Eds. Giakoumakis E, Anagnostakis MJ and Petropoulos NP.
Published by National Technical University of Athens, Reprographic Unit, 1996.
6.
Makrigiorgos GM . Identification and tracing of low-level mutations in tumors and their potential influence on drug resistance. Proceedings of the Santorini Biologie Prospective
Conference, September 30-October 4 2004: From human genetic variations to prediction of risks and responses to the environment. Clinical Chem Lab Med , 42: A21-A60.
7.
Park, Mi-Ae, Mahmood A., Zimmerman R., Limpa-Amara N, Makrigiorgos GM ,
Moore, SC. Influence of non-uniform activity distribution on normal tissue dose from radionuclides with different beta ranges. Proceedings of the 9 th World Congress of
Nuclear Medicine and Biology , October 22-27, Seoul, Korea, 2006.
8.
Cormack RA, Nguyen PL, D’Amico AV, Sridhar S, Makrigiorgos GM Optimal drug release schedule for in-situ radiosensitization of image guided permanent prostate implants. Proceedings of the SPIE Medical Imaging Conference , February 12-19,
Orlando, Florida, 2011.
D. BOOK CHAPTERS
1.
Makrigiorgos GM , Detection of chromatin - associated hydroxyl radicals generated by
DNA - bound metal compounds and antitumor antibiotics. Chapter 16 , Volume 36, pp

521-541. In: 'Metal Ions in Biological Systems: Interrelations between Free Radicals and
Metal Ions in Life Processes', A. Sigel, H. Sigel (Eds.); Marcel Dekker: New York, 1999.
2.
Wang G, Price B and Makrigiorgos GM. PCR-based amplification method of retaining the quantitative difference between two complex genomes. Chapter 50 , In Cell
Biology: A Laboratory Handbook, 3 rd Edition, Julio Celis, Editor, Elsevier Publishing,
London, UK, 2005.
3.
Makrigiorgos GM . Genome amplification tolerant to sample degradation: Application to
Formalin-Fixed, Paraffin-Embedded Specimens. Chapter 10 , pp. 149-160, in Methods
Express series, ‘Whole Genome Amplification’, Edited by Simon Hughes and Roger S.
Lasken, Scion Publishing Ltd, Bloxham, Oxfordhsire, UK, 2005
4.
Makrigiorgos GM . Inverse PCR-based RFLP for identifying low-level mutations in tumors. Chapter 14 , In Methods Express series, Edited by Simon Hughes and Roger S.
Lasken, Scion Publishing Ltd, Bloxham, Oxfordhsire, UK, 2007.
5.
Sridhar S, Nagesha DK., Berbeco R, Cormack RC, Makrigiorgos GM . Nanotechnology for radiation oncology. In R. Bawa, G. Audette and I. Rubinstein. (Editors): Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy and Clinical Applications,
Pan Stanford Publishing, Singapore (2015) [ISBN 978-981-4669-20-7 (Cloth), 978-981-
4669-21-4 (eBook)].
6.
Castellanos-Rizaldos E, Milbury C, Guha M and Makrigiorgos GM . COLD-PCR
Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic
Testing. IN: Magdalena Thurin and Francesco M. Marincola (eds.), Chapter 13:
Molecular Diagnostics for Melanoma: Methods and Protocols , Methods in Molecular
Biology, vol. 1102, DOI 10.1007/978-1-62703-727-3_33, Springer Science+Business
Media New York 2014
E. SCIENTIFIC REPORTS
1.
Adelstein, SJ, Howell RW, Humm JL, Makrigiorgos GM , and Wessels BW. Report to the International Commission for Radiation Units and Measurements (ICRU): On the conceptual basis for dose quantities in nuclear medicine. International Commission for
Radiation Units and Measurements Report ICRU/97/13, July 1997, ICRU, 79 Woodmont
Avenue, suite 800, Bethesda, Maryland 20814-3095. Also published in ICRU News,
June 1998, pp. 4-10 .
2.
Makrigiorgos GM , Member, Editorial Advisory Board and Commentary in pp. 75-77 in
Commercial Implications of Advances in the Identification, Mapping and Application of single nucleotide polymorphisms , Eds. Rubenstein K and Branca MA, Cambridge
Healthtech Institute Report Series, December 2001, Cambridge Healthtech Institute,
Cambridge, MA, USA.
3.
Makrigiorgos GM , A novel method to detect low-level mutations in DNA . pp. 253-264,

E. Georgiou, Editor. Special scientific edition of the Laboratory of Medical Physics,
University of Athens, Greece. Parisianos Editions, 2002, Athens, Greece.
F. THESIS.
Makrigiorgos, GM . Characterization of the radiation quality of photon and mixed photon-neutron radiation fields encountered in medical practice. Ph.D Dissertation.
Leeds, UK: University of Leeds, 1984.