EVERY DAY IN MAY NEED TO KNOW Week 1 – History: The Miracle of Antibiotics Date FRIDAY MAY 1 Short fact Antibiotics are losing their power Long fact Antibiotics are losing their power. Reference The development of antibiotics was one of the most important advances of medicine. But now, because of the overuse and misuse of antibiotics, bacterial infections that were once easily cured with antibiotics are becoming harder to treat. Australia is one of the biggest contributors to this problem – but we are also one of many global leaders trying to make a change. That change starts with you. You need to know the facts about antibiotic resistance, and we’re here to tell you. Every day in May we’ll be sharing important information that you need to know. Spread knowledge, not infections. It’s up to you and every Australian to save so they work when we need them to. MONDAY MAY 4 Before antibiotics, bacterial infection was a leading cause of death Before antibiotics, infection was a leading cause of death. You could die from a single cut or scrape if infection set in. Now, with antibiotics in our lives, death by infection is only a very small percentage of what it was one hundred years ago. Reference: http://www.abs.gov.au/AUSST ATS/abs@.nsf/Lookup/4102.0 Main+Features10Mar+2011/ TUESDAY MAY 5 The discovery of penicillin was so important, it was awarded a Nobel Prize What would happen now if we lost the miracle of antibiotics? General Record of Incidence Mortality (GRIM) books The ‘wonder drug’: the discovery of penicillin was so significant it was awarded the Nobel Prize in Physiology or Medicine in 1945. Ref: Nobel Prize website http://www.google.com.au/url? sa=t&rct=j&q=&esrc=s&frm=1 &source=web&cd=1&ved=0CB 4QFjAA&url=http%3A%2F%2F www.nobelprize.org%2Fnobel _prizes%2Fmedicine%2Flaure ates%2F1945%2F&ei=ZP8tVd rOoHXmAWBwID4Cw&usg=AF QjCNGtxXAbEhlwhhDMo8nRj Du_Fhuk5Q&sig2=YSlMHzrsu 11tqny_h5LVlQ&bvm=bv.9079 0515,d.dGY In 1945, Alexander Fleming, Howard Florey and Ernst Chain were awarded the Nobel Prize in Medicine for having contributed to discovering penicillin. Now, 70 years later the ‘precious resource’ of antibiotics is losing its power because of the common misuse of antibiotics. WEDNESDAY MAY 6 100 years ago there was no effective cure for common bacterial infections 100 years ago, before the widespread use of antibiotics, there was no effective cure for common bacterial infections. Between 1922 and 1924, infectious and parasitic diseases caused 15% of all deaths in Australia. By 1966, they caused less than 1% of all deaths. This reduction is generally believed to be the result of medical advances including the availability of antibiotics from the 1940s. What would happen now if we lost the miracle of antibiotics? {1)Reference: http://www.healthychildren.org/ English/healthissues/conditions/treatments/P ages/The-History-ofAntibiotics.aspx Source: http://www.abs.gov.au/AUSST ATS/abs@.nsf/Lookup/4102.0 Main+Features10Mar+2011#1 0 Australian Institute of Health and Welfare, 2000, Australia's Health 2000, AIHW cat. no. 19, viewed 24 February 2011, <www.aihw.gov.au>. THURSDAY MAY 7 Doctors used to be powerless against serious bacterial infections Before antibiotics, doctors used to be powerless against serious bacterial infections. The only option for severe bacterial infections was to hope that a person’s own immune system would overpower the infection. But, for millions each year this never happened. (Reference: Penicillin:Medicine's Wartime Wonder Drug and Its Production at Peoria, Illinois John S. Mailer, Jr., and Barbara Mason Historical Research and Narrative) What would happen now if we lost the miracle of antibiotics? http://www.lib.niu.edu/2001/iht 810139.html FRIDAY MAY 8 *WEEKEND SUPER FACT* Before antibiotics, simple bacterial infections could kill The world before antibiotics Before the first antibiotics were prescribed in the 1940s, bacteria was a killer. A small cut could become fatal if it became infected, and routine surgery and childbirth were fraught with the risk of infection. What would happen now if we lost the miracle of antibiotics? amr-review.org http://amrreview.org/sites/default/files/A MR%20Review%20Paper%20 %20Tackling%20a%20crisis% 20for%20the%20health%20an d%20wealth%20of%20nations _1.pdf (see page 3) Try going to amr-review.org and opening the December 2014 document. This reference is on page 3. Week 2 – Current affairs: The super bug Date MONDAY MAY 11 Short fact Antibiotic resistance is not coming – it is here right now Long fact Antibiotic resistance is not coming – it is here now Antibiotic resistance happens when bacteria mutate in response to antibiotic use . Antibiotic resistance is a global issue and affecting Australians today. You may have already heard of resistant strains, sometimes referred to as ‘superbugs’, like MRSA - Methicillin-resistant Staphylococcus aureus Multi-drug resistant E. coli in urinary tract infections is present in Australia. Failure of the last resort antibiotic treatment for the sexually transmitted infection gonorrhoea has even occurred in Australia. In April 2014, the World Health Organization (WHO) released the first global report on antibiotic resistance. Reference Ref: taken from our AAW ‘Fact Sheet’ http://www.nps.org.au/medicines/infections -and-infestations/antibiotics/forindividuals/what-is-antibiotic-resistance http://www.nps.org.au/publications/healthprofessional/health-newsevidence/2014/antimicrobial-resistance E coli reference: ‘antibiotic resistance remains a serious health threat despite discovery’ media release from 13 Jan, 2015 Gonorrhoea reference: AAW 2014 fact sheet. The report confirmed high rates of antibiotic resistance in bacteria that cause common community and hospital infections (eg, pneumonia, urinary tract infections) around the world. TUESDAY MAY 12 Don’t ask for antibiotics when you don’t need them Antibiotics are a dying breed. Don’t be part of the problem: don’t ask for antibiotics when you don’t need them. 1 in 5 Australians expect antibiotics for viruses like a Reference: from Evaluation of the RAR Program Summary Report, September, 2014, National Consumer Survey cold or flu, and 17% would ask a doctor to prescribe antibiotics, even though they won’t work on a viral infection. WEDNESDAY MAY 13 Australians take a lot of antibiotics Australians take A LOT of antibiotics. Australia has one of the higher rates of antibiotic use in the OECD. 24 million antibiotic prescriptions are written in Australia each year. Put in perspective, that’s enough for one prescription for every Australian. Reference and graph: graph: http://www.oecdilibrary.org/sites/health_glance-2011en/04/11/index.html;jsessionid=1m9l6pqjd3 gpn.x-oecd-live03?itemId=/content/chapter/health_glance2011-39en&_csp_=db5be54dd412d545669fd5afad 63b56d http://www.nps.org.au/media-centre/mediareleases/repository/antibiotic-resistanceremains-a-serious-health-threat-despitediscovery http://www.oecd-ilibrary.org/social-issuesmigration-health/health-at-a-glance2013/overall-volume-of-antibioticsprescribed-2010-or-nearestyear_health_glance-2013-graph99-en THURSDAY MAY 14 The pipeline of new antibiotics is drying up “They’ll just make new, stronger antibiotics…”: A common misconception is that when we run out of effective antibiotics for common infections, we’ll just develop more. In fact, new antibiotics are rare, and the once large number of pharmaceutical companies investing in antibiotic research has dwindled. The most recent discovery, teixobactin, still needs to undergo further studies and testing in humans, which will take Reference http://www.nps.org.au/mediacentre/media-releases/repository/antibioticresistance-remains-a-serious-health-threatdespite-discovery) Antibiotic development is dwindling graph http://www.cdc.gov/getsmart/week/downloa ds/gsw-factsheet-future.pdf) many years, but even then it won’t be effective on all bacterial infections. FRIDAY MAY 15– *WEEKEND SUPER FACT* Antibiotic resistance is one of the greatest threats to human health today Antibiotic resistance is one of the greatest threats to human health today. The World Health Organization has identified antibiotic resistance as “one of the greatest threats to human health today … no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country”. reference: http://www.cdc.gov/drugresistance/p df/ar-threats-2013-508.pdf http://www.who.int/mediacentre/news/relea ses/2014/amr-report/en/ A 2013 report estimated that in the United States every year, two million people fall ill and 23,000 people die from antibiotic-resistant infections. The problem is growing. Preserve the miracle of antibiotics. Week 3 – What if: Imagine a world without antibiotics Date MONDAY MAY 18 Short fact Imagine a world without antibiotics Long fact POST ANTIBIOTIC-ERA The World Health Organization is warning us that we may be heading towards a “post-antibiotic era” – in which common infections and minor injuries can kill. Can you imagine a world without antibiotics? According to the White House’s National Strategy for Combating Reference Ref: http://www.who.int/mediacentre/news/rele ases/2014/amr-report/en/ http://www.cdc.gov/drugresistance/pdf/car b_national_strategy.pdf Antibiotic Resistant Bacteria, “in a world with few effective antibiotics, modern medical advances such as surgery, transplants, and chemotherapy may no longer be viable due to the threat of infection.” TUESDAY MAY 19 What if you develop an infection that is resistant to antibiotics? What if you develop an infection that is resistant to antibiotics? If you or a memberof your family develop an antibioticresistant infection, you will have the infection for longer, you may be more likely to have complications from the infection, you could remain infectious for longer and pass your infection to other people. And some antibiotic resistant infections could in fact become untreatable. WEDNESDAY MAY 20 Antibiotic resistance knows no geographical bounds Superbug stowaways can hitch a ride with travellers Travellers can return to Australia infected with multidrug-resistant organisms, particularly ones that cause tuberculosis, gonorrhoea or hospital-acquired infections. Patients with resistant bacteria faced extended hospital stays of 1 to 4 months. Ref: AAW 2014 fact sheet http://www.nps.org.au/medicines/infection s-and-infestations/antibiotics/forindividuals/what-is-antibiotic-resistance Ref: http://www.nps.org.au/publications/healthprofessional/health-newsevidence/2014/superbug-stowaways Such complications could become commonplace if antibiotic resistance continues its uncontrolled geographical spread. THURSDAY MAY 21 A precious resource is losing its power “A precious resource” is losing its power. According to the White House’s National Strategy for Combating Antibiotic Resistance, “antibiotics are a precious resource” and “preserving its usefulness will require cooperation and collaboration.” Everyone has a part to play in the fight against antibiotic http://www.cdc.gov/drugresistance/pdf/car b_national_strategy.pdf resistance. FRIDAY MAY 22– *WEEKEND SUPER FACT* Antibiotic resistance in 2050: 10 million deaths a year? Where will you be in 2050? A UK report has estimated that a continued rise in antibiotic resistance by 2050 would lead to 10 million people dying every year with a financial cost to the world of up to US$100 trillion. Reference: review on Antimicrobial Resistance, Amr-review.org Full reference http://www.jpiamr.eu/wpcontent/uploads/2014/12/AMR-ReviewPaper-Tackling-a-crisis-for-the-health-andwealth-of-nations_1-2.pdf We need to act now to stop the spread of antibiotic resistant bacteria. Week 4 – Here and now: Colds and flu — what you can do Date MONDAY MAY 25 TUESDAY MAY 26 Short fact Antibiotic-resistant bacteria can develop in your body after a course of antibiotics Long fact Think of your body as a human Petri dish Reference Reference: AAW 2014 fact sheet If you have recently taken antibiotics, you can have antibiotic resistant bacteria develop then persist in your body for as long as twelve months. They can multiply and become strong enough to resist antibiotics in the future. These antibiotic-resistant bacteria can then be passed on to family members or other people in the community. http://www.nps.org.au/medicines/infectionsand-infestations/antibiotics/forindividuals/what-is-antibiotic-resistance Antibiotics don’t work for all infections Antibiotics do not work for all infections. They don’t treat viral colds and flu; and most coughs, earaches, sinus congestion and sore throats will get better without antibiotics. Reference: NPS website http://www.nps.org.au/medicines/infectionsand-infestations/antibiotics/forindividuals/antibiotics-for-respiratory-tract- If you are usually healthy and well, your immune system will take care of most respiratory tract infections— including viral and some bacterial infections — by itself. Be part of the solution: don’t demand antibiotics; tell your doctor that you only want antibiotics if they are truly necessary. WEDNESDAY MAY 27 THURSDAY MAY 28 Green snot doesn’t mean a lot Simple steps to avoid infections infections/for-individuals/overview Green snot doesn’t mean a lot. Reference: AAW 2014 fact sheet Coloured mucous or ‘snot’ isn’t always a sign of a bacterial infection. Green or yellow coloured snot can in fact be a sign that your immune system is fighting your infection, and not that your illness is getting worse. That also goes for other symptoms including cough, sore throat, earaches and fever. While some people with these symptoms will need antibiotics, most people won’t and will get better without antibiotics. Of course, if your symptoms continue to get worse, see your doctor. http://www.nps.org.au/conditions/respiratoryproblems/respiratory-tract-infections/forindividuals/conditions/common-cold/forindividuals/symptoms Be part of the solution: simple steps to avoid infections. Reference: NPS website It’s easy to take simple steps to avoid infections and to stop them from spreading. You can do this by washing your hands, coughing and sneezing into a tissue and throwing it away, and staying home when you are sick. Staying home when you are sick will help you get over the infection faster, and it will also mean that you won’t spread your infection. Having a flu vaccination every year before winter can help to protect you from getting the flu. http://www.nps.org.au/conditions/respiratoryproblems/respiratory-tract-infections/forindividuals/prevention FRIDAY MAY 29 *WEEKEND SUPER FACT* Antibiotics won’t make your cold or flu better faster. We know what needs to be done to solve the crisis… we’re just not doing it. Think before you ask. Antibiotics WILL NOT: Backup fact Sharing antibiotics can contribute to antibiotic resistance Reference: NPS website http://www.nps.org.au/medicines/infectionsand-infestations/antibiotics/forindividuals/antibiotics-dont-kill-viruses help a cold or flu get better faster stop a cold or flu from getting worse stop a cold or flu from spreading to other people. Never share antibiotics with another person. Each antibiotic treats specific bacteria. Using the wrong antibiotic can cause resistant bacteria to grow, and may lead to a longer and more serious infection by delaying correct treatment. Properly dispose of any leftover antibiotics—don’t save them for future use. : Our cold messaging on website http://www.nps.org.au/conditions/respiratory-problems/respiratory-tract-infections/forindividuals/conditions/common-cold/for-individuals/medicines-and-treatments Cold prevention messaging on website http://www.nps.org.au/conditions/respiratory-problems/respiratory-tract-infections/forindividuals/conditions/common-cold/for-individuals/prevention