OIE Reference Laboratory Reports
Activities in 2011
Name of disease (or topic) for
which you are a designated OIE
Reference Laboratory:
Address of laboratory:
Sheep pox and Goat pox
Sheep pox and Goat pox Reference Laboratory,
Razi Vaccine and Serum Research Institute,
Hessarak, Karaj
PO Box 31975/148
IRAN
Tel.:
(98-21) 3117908
Fax:
(98-261) 4552194
e-mail address:
hr_varshovi @yahoo.com, int@rvsri.com
website:
Name (including Title and
Position) of Head of Laboratory
(Responsible Official):
Name(including Title and
Position) of OIE Reference
Expert:
Hamid Reza Varshovi,
DVM, PhD
Head of Animal Viral Vaccines Department
Hamid Reza Varshovi,
DVM, PhD
Head of Animal Viral Vaccines Department
Name (including Title and
Position) of writer of this report
(if different from above):
Annual reports of OIE Reference Centres, 2011
1
Sheep pox and Goat pox
Part I: Summary of general activities related to the disease
1.
2.
Test(s) in use/or available for the specified disease/topic at your laboratory
Test
For
Specificity
Total
Virus neutralisation test (VNT) based on NI
Antibody
Group
15
VNT
Antigen
Group
30
Electron microscopy (EM)
Virus detection
genus
1
Susceptible animal inoculation
Virus detection
Group
30
Polymerase chain reaction (PCR)
DNA detection
genus
48
PCR-RFLP
DNA detection
Host species
25
Lamb kidney (LK) and lamb testis (LT) and Vero
cell cultures
Virus isolation
-
3
Production and distribution of diagnostic reagents
Type of reagent
Amount supplied nationally
(including for own use)
Sheep pox reference virus (MR/ 65 strain)
own laboratory use
Goat pox reference virus (Goargan strain)
own laboratory use
Sheep pox & Goat pox virulent challenge viruses
own laboratory use
GPV antigen
40 ml
SPV antigen
50ml
GPV hyperimmune serum
80 ml
Part II: Activities specifically related to the mandate
of OIE Reference Laboratories
3.
International harmonisation and standardisation of methods for diagnostic testing or the
production and testing of vaccines
a)
Establishment and maintenance of a network with other OIE Reference Laboratories
designated for the same pathogen or disease and organisation of regular inter-laboratory
proficiency testing to ensure comparability of results
None
2
Annual reports of OIE Reference Centres, 2011
Sheep pox and Goat pox
b)
Organisation of inter-laboratory proficiency testing with laboratories other than OIE
Reference Laboratories for the same pathogens and diseases to ensure equivalence of
results
None
4.
Preparation and supply of international reference standards for diagnostic tests or vaccines
Not yet applicable
5.
Research and development of new procedures for diagnosis and control
Development of Real Time PCR technique for detection and differentiation of SPV and GPV is undergoing.
6.
Collection, analysis and dissemination of epizootiological data relevant to international disease
control
Molecular characterization of Iranian Capripoxvirus isolates based on GPCR gene is accomplished and the
findings is published through a PhD thesis. The national Project on molecular epidemiology of SGPV in Iran is
planned for 2012
7.
Maintenance of a system of quality assurance, biosafety and biosecurity relevant to the
pathogen and the disease concerned
None
8.
Provision of consultant expertise to OIE or to OIE Member Countries
Collaboration on Animal diseases prioritization Project of OIE for East Africa (sheep and goat pox section)
9.
Provision of scientific and technical training to personnel from other OIE Member Countries
At Razi Institute, the training on Capripoxvirus and Parapoxvirus diagnostic methods as well as sheep pox & goat
pox vaccine production is available.
10. Provision of diagnostic testing facilities to other OIE Member Countries
None requested in 2011
11. Organisation of international scientific meetings on behalf of OIE or other international bodies
None
12. Participation in international scientific collaborative studies
None
13. Publication and dissemination of information relevant to the work of OIE (including list of
scientific publications, internet publishing activities, presentations at international conferences)

No presentation or publication for 2011
_______________
Annual reports of OIE Reference Centres, 2011
3