Faculty of Medicine and Health
School of Medicine
Leeds Institute of Clinical Trials Research
Clinical Trials Research Unit
Associate Clinical Professor and Deputy Director (Cancer Division) of the Clinical Trials
Research Unit / Honorary Locum Consultant in Medical Oncology
Up to 12 months fixed term to cover a period of Maternity Leave
We are seeking an appointment to cover maternity leave of the Deputy Director for the Cancer
Division within the Leeds Institute of Clinical Trials, School of Medicine, Faculty of Medicine and
Health, and an Honorary Locum Consultant in the Leeds Teaching Hospitals NHS Trust (LTHT).
The successful candidate will be the clinical lead in the early and late phase portfolios of the
cancer division, with involvement in the development and implementation of research strategy.
They will be primarily responsible for clinical input into the early phase portfolio of solid tumour
clinical trials, including leading ongoing studies (e.g. JX594), as appropriate, and involved in
securing funding for future studies (as chief investigator/co-applicant on grant applications).
As part of the role you will also undertake clinical activities in the gastro-intestinal medical
oncology practice at St James’s University Hospital fully supported by junior staff and specialist
nurses
You will be a member of the Royal College of Physicians (UK) or equivalent, and have completed
higher specialist training in medical oncology (or equivalent). You will be on the GMC’s Specialist
Register or within six months of being admitted to the Register for trainees if currently in a training
programme within the UK or an established consultant. You must have appropriate research
experience in the field of clinical trials to support this role within the trials unit.
The University of Leeds is committed to providing equal opportunities for all and offers a
range of family friendly policies (http://hr.leeds.ac.uk/homepage/4/policies). The University
is a charter member of Athena SWAN and holds the Bronze award. The School of Medicine
gained the Bronze award in 2013. We are committed to being an inclusive medical school
that values all staff, and we are happy to consider job share applications and requests for
flexible working arrangements from our employees.
Salary will be on the clinical scale for the New Consultant Contract £75,249 - £101,451 p.a.
Informal enquiries are encouraged and should be directed to Professor Julia Brown
j.m.b.brown@leeds.ac.uk +44(0)113 3431499
If you require assistance with your online application please contact ctrujobs@leeds.ac.uk or
+44(0)113 3431477
Job Ref: MHCTR1013
Closing date: 19 April 2015
Main purpose of the post
The post-holder will be the Clinical Lead within the Cancer Division of the Clinical Trials Research
Unit, including the early and late phase portfolios, and Associate Clinical Professor/Honorary
Consultant in Medical Oncology based at St James’s University Hospital for clinical practice and
clinically based research. The post-holder’s clinical responsibility will be to work as part of an
established GI medical oncology team. They will conduct clinical cancer research at the
international forefront, contribute to academic excellence in oncology and practice medical
oncology in gastrointestinal cancer to the highest standards.
Main Duties and responsibilities
General:
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To contribute to the development and achievement of University, faculty and school strategy
within the context of an international, research-led university.
To be recognised as an authority in the field, developing and maintaining an external profile
as appropriate to the discipline.
To maintain scholarly activity and keep up to date with developments in the field as necessary
to carry out the duties of the post.
To carry out the duties of the post in accordance with the University values and standards,
including the Leadership and Management Standard, and in line with University policies and
procedures and local faculty/school benchmarks as appropriate, upholding high professional
standards and leading by example.
To work with our students as members of a learning community to provide world class
education and an excellent student experience.
To maintain own continuing professional development.
To maintain a safe work environment, including ensuring compliance with health and safety
legislation and the undertaking of appropriate risk assessments.
To integrate the University value of inclusiveness into all appropriate aspects of the job;
respecting the dignity and diversity of all members of the University community and of visitors
to the University.
Provide Academic Leadership:
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Contribute to the development of strategic direction, strategy development and implementation
of LICTR, taking a lead in directing and developing the early and late phase Cancer Portfolio
Identify and establish strategic partnerships with clinical and academic collaborators to develop
and promote the Cancer Portfolio
Identify and establish strategic partnerships with researchers to develop and promote the
associated methodological research portfolio
Maintain a senior clinical presence in LICTR
As a member of the LICTR Senior Management Team support team and role development
As a member of the LICTR Senior Management Team support the management and
development of staff, in a complex working environment
Significant contribution to the overall work of the University and/or equivalent external
organisations by representing the school and faculty on appropriate committees and groups
Effective contribution to the management and administrative processes and committee
structures of the school, faculty and University
Managing or leading major initiatives or areas of work (as either sustained or one-off projects)
which facilitate school, faculty or University performance or business as required
Involvement in the recruitment, management and development of staff and act as a mentor to
more junior/less experienced colleagues
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The promotion of the values of collegiality within the academic community
Actively promoting and embedding University standards of employment practices across the
School
Research, Innovation, Clinical Duties and Trial Conduct
As an Associate Clinical Professor the successful candidate will conduct international-level basic,
translational and/or clinical research equating to 5 PAs, facilitating the development of a research
programme, with the support of established laboratory and clinical research teams. He/she will:
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To pursue, develop and lead research, innovation and impact at an appropriately benchmarked
level
To develop the strategic direction within own research area
To promote the integration of own research area with other research interests within and, as
appropriate, outside the school and faculty
To maintain a high quality record of regular and original research publications of external
standing as appropriate to the field or discipline
To attract research income on an individual and collaborative basis, as appropriate to the field
or discipline, to underpin high quality research activity
To provide high quality postgraduate supervision and attract research students to the
University
To take part in knowledge transfer activities, where appropriate and feasible
Undertake clinical activities (5 PAs) in the medical oncology practice at St James’s University
Hospital fully supported by junior staff and specialist nurses
Undertake clinical research to facilitate the development of a personal clinical research
programme, with the support of established research teams
Undertake ad hoc teaching duties in keeping with those of an Associate Clinical Professor /
honorary teaching hospital consultant physician.
Lead a clinical trials research portfolio conducting international trials within the sphere of
LICTRs research strategy
Be involved in obtaining research grants for large multi-centre national clinical trials and
smaller early phase trials to be conducted through LICTR as Chief Investigator/LICTR
Scientific Lead
Continue delivery of ongoing projects clinically led at LICTR
Promote the academic profile of the LICTR through high quality publications in peer-reviewed
clinical and methodological journals
Present research at local, national and international conferences
Undertake grant review and journal refereeing
Establish and maintain professional relationships with personnel from other Trials Units and
associated organisations (national and international)
Identify funding opportunities for appropriate methodological research
Academic outcomes are subject to annual review within Leeds Institute of Clinical Trial Research
as part of the joint Appraisal/Job Planning process between UoL and LTHT.
Quality Assurance and Regulation
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Provide clinical oversight of the design, conduct and analysis of cancer clinical trials conducted
within the LICTR
Support the ongoing development and implementation of rigorous trial conduct, legal, ethical
and regulatory requirements within LICTR practice and Standard Operating Procedures
Maintain understanding of regulatory and governance environment and assess impact on
Health Sciences portfolio. This will include the EU Directive for Clinical Trials, Human Tissue
Bill and Data Protection Act
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Identify the need for new/revised Standard Operating Procedures and guidelines
Teaching
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To add to and maintain excellence in teaching, the appointee will be expected to carry out
limited undergraduate student teaching within appropriate curricula, and contribute to postgraduate and post-doctoral research training and/or academic/clinical supervision of junior
medical staff in Rheumatology
To undertake research-led teaching1 at different levels on undergraduate and/or postgraduate
taught courses, regularly collecting, and responding to, student feedback.
To contribute at an appropriate level to school and faculty policy and practice in teaching.
To play a significant role in the design, development and planning of modules and programmes
within the subject area as required.
To play a significant role in the review of modules and programmes and in quality assurance
and enhancement as required.
To develop innovative approaches to learning and teaching as appropriate.
To provide timely feedback and assessment of coursework and examinations.
To provide general support and guidance to students, resolving issues and/or referring to
specialist parties, where appropriate.
To act as a personal tutor, including pastoral care and supporting students in maximising the
benefit of their time at Leeds.
To supervise students undertaking research projects as appropriate.
The extent of the appointee’s teaching responsibilities will be determined by their teaching
commitment, agreed through the joint job planning exercise.
This job description provides a framework for the role and it may be necessary for an Associate
Clinical Professor to undertake any duties commensurate with the post as might reasonably be
required
Details of current academic (clinical and non-clinical staffs) can be provided to you.
Key Relationships
i) Within LICTR the appointee will be a member of the senior management team and contribute to
strategic direction of the Unit, formally reporting to the Director of LICTR through whom they will
be ultimately accountable to the Deans of Medicine and the Faculty of Medicine and Health.
ii) Within SOCR, the appointee will be a full academic member and contribute to clinical research
and appropriate Learning and Teaching and be a member of the Clinical Research Group, with a
line of accountability to the head of the Clinical Research Group and an agreed mentoring
arrangement with senior clinical academics.
iii) Clinically the post-holder will work closely with other members of the GI oncology team
(including three medical oncologists (Professor Matt Seymour, Dr Alan Anthoney and Dr Daniel
Swinson) and six clinical oncologists (Professor David Sebag-Montefiore, Dr Adrian Crellin, Dr
Rachel Cooper, Dr Ganesh Radhakrishna, Dr Paul Hatfield).
University Values
All staff are expected to operate in line with the university’s values and standards, which work as
an integral part of our strategy and set out the principles of how we work together. More
1
It is recognised that academics will, at times, teach subjects that are not closely related to their research specialism, in
which case research and scholarship may inform, rather than lead, their teaching.
information about the university’s strategy and values is available at
http://www.leeds.ac.uk/comms/strategy/
Person Specification
The Appointee must have completed a period of research training and have obtained or be in the
process of writing up a postgraduate research degree (PhD or MD) in a clinical trial-related
subject.
The Appointee must have completed higher specialist training (or equivalent) in Medical Oncology.
You must be on the Specialist Register for Medicine (or be within six months of being admitted to
the Register for trainees currently in a training programme within the UK). In accordance with the
regulations, all other categories of doctors must be on the Specialist Register to be eligible for
consideration for a Consultant appointment by the Advisory Appointments Committee. Applicants
must provide information regarding their status from the GMC and/or relevant Royal College at the
time of application, in order for their application to be progressed further.
The research contribution from you must be, or become, excellent. It is therefore expected that
you will have begun to develop, and will continue to build on this, with appropriate research output
in terms of presentations and publications. This aspect of the post will be subject to annual review.
Essential
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Fellowship of the Royal College of Physicians (UK) or equivalent
Must have completed a recognised training programme in medical oncology
On the GMC specialist register in a relevant discipline (medical oncology) or within 6 months
of being so)
Higher research degree (PhD or MD awarded or planned in a clinical research related subject)
A research experience that can be the basis to become internationally excellent
Ability to manage and initiate clinical and translational research
Experience of contributions to clinical research, for example through obtaining informed
consent, treatment delivery and data collection for patients in clinical trials
Ability to write scientific papers, proposals and to publish internationally recognised research
regularly in the cancer research literature
Effective communication skills and the ability to work effectively as part of a team
Have an understanding of current NHS management and Trusts and be aware of the
responsibilities that a consultant post brings
Highly self-motivated and able to organise time and workload Experience in the development
and implementation of clinical trials within the current legal, ethical, regulatory and CONSORT
frameworks
Effective organizational skills demonstrated by proven ability to prioritize work and
successfully initiate, manage and complete projects
Capacity for original thought and to solve problems, identify issues and plan strategic action
Ability to work effectively both independently and collaboratively
Experience in developing, implementing and monitoring policies, guidelines and Standard
Operating Procedures
Effective communication, presentation and organisational skills
Strategy development and implementation
Experience and ability to participate constructively in complex multi-disciplinary meetings and
decision making processes
Desirable
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Experience in the management of gastrointestinal cancers
Previous experience of developing, delivering and reporting clinical trials
Honorary Consultant Contract
You will be awarded an honorary NHS contract with the Leeds Teaching Hospitals NHS Trust.
Working arrangements
St James’s Institute of Oncology:
In January 2008, oncology services across Leeds were relocated into a new £220M, 63,000m2
Oncology Wing (the Bexley Wing) on the St James's University Hospital campus. This
incorporates services in non-surgical oncology, haematology, the Academic clinical offices and
support areas and substantial services in cancer surgery. The St James's Institute of Oncology
also includes designated Cancer Research UK funded beds for patients in early clinical trials.
The Bexley Wing, the principal base of the St James’s Institute of Oncology, is one of the largest
oncology facilities in the UK, within one of the largest acute general hospitals in Europe. There
are 350 beds (100 non-surgical oncology), day-care and outpatients facilities, 12 radiotherapy
bunkers, operating theatres, full imaging support and dedicated clinical cancer research facilities.
Clinical Trials Group:
This group (led by Professor Matt Seymour), is part of the Oncology and Clinical Research section
of the University of Leeds Institute of Molecular Medicine. It develops and runs high-quality clinical
research trials in a range of cancer sites. The group has close links with the Clinical Trials
Research Unit (Professor Julia Brown) and with the Early Clinical Trials Group (Professor Chris
Twelves), with whom collaboration is encouraged. We also have strong links within LIMM for
translational studies within RCTs, notably in GI cancer.
Cancer Research UK Centre:
The Cancer Research UK Centre undertakes research in Cancer Medicine and Pathology,
Biotherapy, Cell Biology, Clinical Cancer Proteomics, Genetic Epidemiology, Immunotherapy,
Molecular Genetics, Psychosocial and Clinical Practice Research and Drug Development.
Research income is approximately £10M per annum with approximately 200 staff. Further
information regarding the research portfolio is available on request.
Research accommodation is principally provided on the St James's University Hospital campus in
the new Wellcome Trust Brenner Building, the Cancer Research Building, Clinical Genetics
Building and Cancer Resource and Information Centre but is also to be found at the Leeds
General Infirmary.
Job plan and Working arrangements
The job plan will incorporate clinical PAs and academic PAs. A sample job plan is outlined below but
the precise details will be dependent on the interests and expertise of the successful candidate.
A job plan review will take place annually, normally with the Trust Clinical Director or Clinical
Management Team, and the Leeds academic lead or Head of Section. The annual job plan review
may result in a revised prospective job plan. There may be an interim review of the job plan where
duties, responsibilities, accountability arrangements or objectives have changed or need to
change significantly within the area.
The post is subject to clinical governance arrangements through the NHS Trust and a rolling
programme of Audit is conducted, with support.
There will be an indicative job plan based on 5 Clinical PA’s and 5 Academic the exact
details of the sessional timetable will be negotiated with the successful candidate. The
duties of the post may be changed with the agreement of the post holder and funding
bodies. Please contact Dan Swinson on 0113 206 8138 or Fiona Collinson on 0113 206 7812
to discuss in more detail.
On-call. The post-holder will join the on-call rota for medical oncology (currently 1 week in 18).
When “on-call” the post-holder will be required to review acute admissions at SJIO each morning
and afternoon and therefore will not be able to deliver normal academic commitments during these
weeks. The post-holder would also be expected to review patients on Saturday and Sunday and
during evenings/nights when clinically required.
Joint Appraisals
In line with the Follett Report recommendations, the University of Leeds has been working closely
with the local NHS Trusts in implementing joint appraisals. You will be expected to participate in a
joint appraisal arrangement as agreed locally on an annual basis. The ‘joint appraisal’ will be
conducted by two appraisers, one from the University and one from the NHS, working together
with one appraisee on a single occasion. There will be annual job planning meetings.
Continuing Medical Education
The Trust fully supports the requirement for CME by the relevant Royal College and acknowledges
that it is an essential component of a consultant’s professional activities that will be reviewed during
the appraisal process and revalidation. Time and financial support for these activities will be granted
in accordance with the Trust’s Leave Policy.
Resources available to support you:
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Staff – details are provided on the appendices attached
Outpatient clinics – in Leeds, the oncology clinic areas will be available to the Consultant
Inpatient facilities – inpatient facilities will be provided within the bed-base of non-surgical
oncology in the Institute of Oncology
Research programme and criteria – you will be encouraged to facilitate and contribute to the
current clinical research programs on-going in the department
A shared office with IT facilities (PC, email etc) will be provided at St James’s, in LICTR there
will be an office and access to admin assistance
Secretarial support
Faculty Information
With more than 6,000 students, 1,600 staff and annual research income of £50m, the Faculty of
Medicine and Health at Leeds is bigger than some universities. Leeds has one of the largest
medical and bioscience research bases in the UK, and is an acknowledged world leader in cancer,
cardiovascular, psychiatric, genetic, musculo-skeletal and health services research. Treatments
developed in Leeds are transforming the lives of people around the world living with conditions
such as HIV, TB, diabetes and malaria.
The School of Medicine
The School of Medicine at the University of Leeds is a major international centre for research and
education. Our ambition is to improve health and reduce health inequalities, locally and globally,
through excellent scientific research and the translation of that research into healthcare practice,
and through the education of future scientific and clinical leaders who will advocate and practise
an evidence-based approach. Our major strategic aims are to:
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Deliver outstanding research including basic discovery science through to applied health
research that makes a significant difference to health.
Produce exceptional graduates, clinicians, educators, doctoral and post-doctoral fellows
whose learning has been informed and inspired by our research excellence and who will
form the next generation of academic and clinical leaders.
Develop and support knowledge transfer activities that flow from our academic activities.
Create and maintain an efficient and sustainable environment for research and teaching
within an organisational culture and management style that enacts and supports the
university’s core values of community, inclusiveness, integrity and professionalism.
The School of Medicine is organised into seven Institutes. All are committed to high quality
research-led teaching, through their training of postgraduate research students, delivery of
postgraduate taught courses, and its leadership in undergraduate teaching. The School works
closely with the local NHS, having a number of jointly funded clinical posts to ensure this
relationship is effective and strong for both research and student education.
Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), Director: Professor
Mark Kearney)
LIGHT integrates basic and clinical scientists with a common goal of understanding the
mechanisms underpinning common chronic diseases of human health and developing new
approaches to treating patients at an individual and population level. At the heart of LIGHTs
philosophy is a vibrant multidisciplinary approach to science that provides a platform to deliver
internationally competitive translational research and teaching in disorders including
cardiovascular disease, diabetes, cancer and neurodegenerative diseases) our key aim is to
improve the lives of our patients and the experience of our students.
Leeds Institute of Health Sciences (LIHS) Director: Professor Tim Ensor
LIHS delivers problem-driven research that supports decisions about the content or delivery of
healthcare. Our interdisciplinary approach incorporates expertise in applied health research
designs, health implementation sciences, social sciences, health economics, informatics and
statistics, as well as skills in communicating with basic scientists, policy makers, healthcare
providers, public and patients. We conduct research at the individual, population and
organisational level.
Leeds Institute of Medical Education (LIME) Director: Professor Trudie Roberts
LIME provides the administrative support, co-ordination and leadership for the School of
Medicine’s undergraduate medical degree, including admissions, curriculum development,
assessment, student support and clinical placement liaison. It provides the technology-enhanced
learning and innovation support for the School of Medicine. LIME also has a very active
scholarship programme of research and innovation in medical education and uses its expertise to
influence medical education policy and practice nationally and internationally. To achieve this it
works with a range of stakeholders including the academic community, the profession, the public,
regulators and policy makers.
The Leeds Institute of Cancer Studies and Pathology (LICAP) Director: Professor Tim
Bishop
The Leeds Institute of Cancer Studies and Pathology addresses both laboratory based and clinical
research into cancer with a major focus on translational science. LICAP is one of the largest
cancer Institutes in the country and has major financial support from the cancer charities. The
laboratories and clinical research are all based on the St James’s site with laboratory activities
being located in the Wellcome Trust Brenner Building and adjacent buildings while the clinical
work is based within Bexley Wing. The Institute consists of seven Sections with the following
interests:
Leeds Institute of Biomedical & Clinical Sciences (LIBACS) Director: Professor Philip
Hopkins
LIBCS undertakes clinically-driven research from the level of the gene through cellular, tissue and
organ to clinical trials. Our vision is to develop a sustainable centre of excellence for the
advancement of patient care by translating research results into clinical practise and contributing
to medical education at undergraduate and postgraduate levels. Our research interests are
encapsulated in 6 clinical themes (Gastrointestinal inflammation & tumorigenesis, Genetic
disorders, Infection & immunity, Neuroscience, Perinatal medicine, Perioperative outcomes &
technologies) underpinned by 4 generic science technology strands (Animal models, Cell biology,
Gene regulations & Genomics). We are based predominantly at the St James’s University Hospital
site.
Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Director: Professor
Paul Emery
LIRMM is dedicated to improving diagnosis, therapy, intervention and outcome across the
spectrum of rheumatic and musculoskeletal medicine. It boasts a dynamic portfolio of research
and education, delivering wide-ranging clinical, translational and basic research across five
Sections: Clinical Musculoskeletal Medicine, Experimental Musculoskeletal Medicine, Clinical
Biomechanics and Physical Medicine, Rehabilitation Medicine and Orthopaedics. A multidisciplinary approach is the core of our activities, with significant interdisciplinary links between
Experimental and Clinical research. LIRMM’s clinical activities are focussed at Chapel Allerton
Hospital, which is also base for our NIHR Musculoskeletal Biomedical Research Unit (LMBRU)
and our basic sciences at St James’s University Hospital.
Leeds Institute of Clinical Trials Research (LICTR) Director: Professor Julia Brown
LICTR delivers innovative design, delivery and knowledge transfer in clinical trials research. Our
multidisciplinary approach, in collaboration with basic scientists, clinicians, policy makers,
healthcare providers, public and patients and University colleagues, delivers internationally
competitive research and teaching that makes a significant contribution to the evidence base for
healthcare delivery. The Institutes research is conducted through the Clinical Trials Research Unit
where we have expertise in design and conduct of complex clinical trials incorporating novel
designs to evaluate CTIMPs, complex interventions, diagnostics, medical devices and surgery.
Clinical Trials Research Unit (CTRU)
The CTRU is a National Cancer Research Institute (NCRI) accredited and UKCRC Registered
Clinical Trials Unit. It has a national and international reputation for the design and delivery of
innovative, complex, and rigorous multi-centre early to late phase clinical trials. The CTRU
provides multi-disciplinary academic leadership with input to all aspects of trials activity, including
statistical design, protocol development, randomisation, development of outcome measures, data
management, logistical issues, statistical analysis, interpretation of results and publication. Both
the CTRU’s track record in conducting innovative, complex clinical trials and its associated
methodological research (efficient trial design and analysis, novel outcome measures and patient
reported outcomes, electronic data capture) inform the academic development of this specialised
field of clinical research on a national and international level. The CTRU particularly specialise in
efficient phase 1/2 trials, biomarker driven designs, seamless phase2/3 designs, adaptive designs
and development and evaluation of complex interventions.
The CTRU is organised into three divisions Cancer, Complex Interventions, Comprehensive)
underpinned by a cross cutting methodology division, within which the portfolios reflect both
national priorities and strengths in Leeds:
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Cancer Research Division - Co Directors Prof Julia Brown & Prof Walter Gregory
- Solid Tumours Portfolio
- Haematological Oncology Portfolio
- Psychosocial Portfolio
- Early Phase Trial Portfolio
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Complex Interventions Division - Director Prof Amanda Farrin
- Mental Health Portfolio
- Diet and Obesity Portfolio
- Older People Portfolio
- Stroke Portfolio
- Complex Interventions Portfolio
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Comprehensive Health Research Division – Director Prof Linda Sharples
- Cardiovascular Portfolio
- Musculoskeletal Portfolio
- Oral Health Portfolio
- Skin Portfolio
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Methodology Division - Directors Profs Gregory, Brown, Farrin, Nixon, Sharples
- Statistical Methodology
- Efficient trial design
- Outcome development
- Complex intervention development & evaluation
- Data capture
The CTRU is currently undertaking approximately 100 trials/studies including methodological
studies that underpin scientific rigour in our trial design and analysis. The CTRU has
approximately 140 staff members and grant income is approximately £5 million per
annum. Grants have been achieved from a variety of funders: NIHR, MRC, Cancer Research UK,
BHF, ARUK, Wellcome, LRF, EORTC, European Union Biomed Programme and a variety of
Pharma companies.
Enterprise and Knowledge Transfer
National Networks
LICTR hosts and provides the leadership for the UKCRC Registered Clinical Trials Unit Network
and the NIHR Trial Managers Network.
Research Design Service
LICTR provides the academic leadership for the Leeds hub of the NIHR Yorkshire and Humber
Research Design Service and provides research design advice and consultancy through the RDS.
Teaching
LICTR is committed to high quality research-led teaching and provides training of postgraduate
research students and delivery of postgraduate taught courses.
St James’s University Hospital Campus Infrastructure and Facilities (SCIF) Director:
Professor Pam Jones
This group covers activities that cover School of Medicine functions for Institutes at St James’s
University Hospital that span more than one institute including biomedical research facilities,
student education, IT, health and safety, estates, seminars, PGR studentships and business
support functions. These functions help support the 5 adjacent buildings on the site.
There are 3 Institutes with staff and students at St James’s: LICP (Leeds Institute of Cancer
studies and Pathology), LIBACS (Leeds Institute of Biomedical and Clinical Sciences), LIRMM
(Leeds Institute of Rheumatic and Musculoskeletal Medicine). These three institutes are
dedicated to basic, translational, clinical and health research integrated with student education.
Section of Oncology and Clinical Research (SOCR)
The Section of Oncology and Clinical Research brings together clinical, translational and
laboratory research workers who mainly focus on the development of new approaches for cancer
therapy and patient care. Galina Velikova works on patient-reported outcomes measurement,
psychosocial oncology focusing on applications in clinical practice. Chris Twelves leads a team
focusing on early clinical trials in cancer and Matt Seymour leads a gastrointestinal and lung
cancer group. The National Cancer Research Network (NCRN) led by Matt Seymour oversees
UK clinical trials and other studies in oncology. The group led by Roz Banks and Peter Selby uses
proteomic and genomic approaches to the identification and evaluation of novel biomarkers
particularly in renal cancer. Alan Melcher, Graham Cook and their groups focus on immunology
and its applications to cancer therapies and viral and gene therapy approaches. New groups
include Georgia Mavria (Signal Transduction and Cancer), Steve Griffin (Antivirals and Viral
Oncology), Sean Lawler (Neuro-oncology) and Heiko Wurdak (Brain Tumour Biology and Neural
Stem Cells). Debbie Beirne heads the Clinical Trials Research Group. The Section has an active
portfolio of clinical and healthcare research and close collaborations with colleagues in Leeds and
elsewhere who bring expertise in clinical research methodology and applied health research.
Terms and Conditions
Details of the terms and conditions of employment for all staff at the university, including
information on pensions and benefits, are available on the Human Resources web pages
accessible via the links on the right hand side, or at http://hr.leeds.ac.uk/policies
Pension Scheme
For appointments to academic or professional and managerial grades you will be eligible to join
the Universities Superannuation Scheme (USS) and will automatically be entered into this Scheme
when you commence employment at the University. Full details of the benefits offered by the
Scheme can be found on their website www.usshq.co.uk and more information can also be
obtained from the University Pensions Department.
If you are being appointed to a clinical post with the University, you may retain the right to remain
in the NHS pension scheme.
Disclosure and Barring Service checks
The successful applicant will be required to give consent for the University to check your criminal
record status through independent verification (from the Criminal Records Bureau). Information will
be kept in strict confidence. Your offer of appointment will be subject to the University being
satisfied with the outcome of these checks.
Disabled Applicants
The post is located in the Leeds Institute of Clinical Trials Research. Disabled applicants wishing
to review access to the building are invited to contact the department direct. Additional information
may be sought from the Recruitment Officer, email disclosure@leeds.ac.uk or tel + 44 (0)113 343
1723.
Disabled applicants are not obliged to inform employers of their disability but will still be covered
by the Equality Act once their disability becomes known.
Further information for applicants with disabilities, impairments or health conditions is
available in the applicant guidance.