Form No M-3 (6)
Study Course Description
1.
Course title: Topical Issues in Clinical Immunology and Genetics. Tumour
Immunology. Allergy and Immunity. Metabolism and Immunity
2.
Course code: BUMK_001
3.
Academic unit: Department of Biology and Microbiology, Dzirciema iela 16,
Dzirciema iela 16, Rīga, LV-1007, phone: +371 67061584; e-mail: bmk@rsu.lv
4.
Head of the academic unit: Juta Kroiča, e-mail: Juta.Kroica@rsu.lv
5.
Course author: Associate Professor Inese Mihailova, inese.mihailova@rsu.lv
6.
Teaching staff involved in implementation of the study course: associate professor
Simona Doniņa; assistant professor Natalja Kurjāne; lecturer Inta Jaunalksne, lecturer Ieva
Ziediņa
7.
Faculty, study programme, year of studies and semester: International Student
Department Second Level Professional higher education study programme „Medicine”
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Number of LV credit points (KP): 2
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Number of ECTS points (1KP = 1.5 ECTS): 3
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Language: English
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Course type (compulsory, restricted elective, elective): B - Restricted elective course
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Prerequisites: Microbiology, immunology (the formation of immune system, its
functions), normal anatomy, histology, pathophysiology, biochemistry, pharmacology,
medical genetics, basic preliminary knowledge in clinical medicine.
13.
Course objective: To provide students with knowledge about several topical issues in
clinical immunology: tumour immunology, allergy immunology and the impact of several
metabolic disorders on the human immunity, their clinical manifestations, to provide
assistance in realisation of the role of the knowledge about immunology in clinical medicine
and application of the scientific findings in practice.
14.
Topic outline of the study course:
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Students’ independent work and tasks: Analysis of scientific publications. Writing
of summary on particular theme.
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Learning outcomes:
 knowledge: On successful completion of the course students will be able to describe
reactions of immune response on the process of tumour growth, to provide information on
possibilities of immunological diagnosis and immunological treatment possibilities of
tumours, the role of immune system in origin and pathogenesis of various allergic
diseases, immune diagnosis and possibilities of specific immune therapy of the most
common allergic diseases, to describe the impact of several metabolic disorders (protein-
Form No M-3 (6)
Study Course Description
energy malnutrition, obesity, increased carbohydrate load, zinc and iron deficiency) on
various immune response reactions and their clinical manifestations.
 practical skills: On successful completion of the course students will be able to apply
the knowledge in acquisition of various compulsory medical courses, diagnostics of
various diseases, to distinguish between the most important allergic reactions, to describe
the possibilities of their examination and therapy.
 competence: On successful completion of the course students will be able to apply the
knowledge and skills about immunological disorders in diagnostics of various pathologies
and development of individual examination plan, to realize the role of immunological
changes in the development of various diseases.
17.
Type of final examination (examination, semester test, theoretical test, National
examination): Test
18.
Assessment criteria: • Regular attendance of lectures and practical classes.
• Active participation in discussions on the topic discussed during classes and lectures.
19.
Readings:

Recommended:
1. Roderick Nair, Matthew Helbert. Immunology for medical Students /Second
Edition/ – MOSBY Elsevier. 2007. - 308.pp.
2. PeterJ.Delves, Seamus J. Martin, Dennis R.Burton and Ivan M.Roitt
ROITT’S Essential Immunology /Eleventh Edition/. Blackwell Publishing.
2006., 2008.
3. Vernera Lozovska redakcijā: Praktiskā alergoloģija /Latvijas Universitāte, 2009/
4. R.Fuller & G.Perdigion . „Gut flora, nutrition, immunity and health”, Blackwell
publishing. 2003. pp 276
5. „Tumor Immunology”in „Immunology” R.Coico @ G. Sunshine 6th ed. WileyBlackwell, 2009.p.299.
6. Mechanisms of tumor immunology” in „Medical Immunology”Tr.Parslow et al.
2006. 11th ed. Lange Medical Book. P.568.

Optional:
7. Helen Chapel, Mansen Haeney, Siraj Misbah, Neil Snowden. Essentials of Clinical
Immunology, /5-th edition/ – Blackwell. 2006. - 358.pp.
8. Oxford handbook of CLINICAL IMMUNOLOGY AND ALLERGY /Second
edition/, edited by Gavin Spickett. 2006. 549.pp.
9. 3. Gerd-Rüdiger Burmester, Antonio Pezzutto, Color Atlas of Immunology.
Thieme, 2006.

Other sources:
Internet sources:
http://www.cehs.siu.edu/fix/medmicro/genimm.htm - General immunology
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Study Course Description
http://www.theimmunology.com/ - General immunology, animation
http://cls.umc.edu/COURSES/CLS311/Schd07.doc - Basic and Clinical Immunology
Online Course Materials
http://www.biology.arizona.edu/immunology/tutorials/immunology/main.html introduction of immunology
http://www.immunologylink.com/ - immunology
http://www.microbiologybytes.com/iandi/ImmGloss.html - Glossary of Immunology