Form No M-3 (6) Study Course Description 1. Course title: Topical Issues in Clinical Immunology and Genetics. Tumour Immunology. Allergy and Immunity. Metabolism and Immunity 2. Course code: BUMK_001 3. Academic unit: Department of Biology and Microbiology, Dzirciema iela 16, Dzirciema iela 16, Rīga, LV-1007, phone: +371 67061584; e-mail: bmk@rsu.lv 4. Head of the academic unit: Juta Kroiča, e-mail: Juta.Kroica@rsu.lv 5. Course author: Associate Professor Inese Mihailova, inese.mihailova@rsu.lv 6. Teaching staff involved in implementation of the study course: associate professor Simona Doniņa; assistant professor Natalja Kurjāne; lecturer Inta Jaunalksne, lecturer Ieva Ziediņa 7. Faculty, study programme, year of studies and semester: International Student Department Second Level Professional higher education study programme „Medicine” 8. Number of LV credit points (KP): 2 9. Number of ECTS points (1KP = 1.5 ECTS): 3 10. Language: English 11. Course type (compulsory, restricted elective, elective): B - Restricted elective course 12. Prerequisites: Microbiology, immunology (the formation of immune system, its functions), normal anatomy, histology, pathophysiology, biochemistry, pharmacology, medical genetics, basic preliminary knowledge in clinical medicine. 13. Course objective: To provide students with knowledge about several topical issues in clinical immunology: tumour immunology, allergy immunology and the impact of several metabolic disorders on the human immunity, their clinical manifestations, to provide assistance in realisation of the role of the knowledge about immunology in clinical medicine and application of the scientific findings in practice. 14. Topic outline of the study course: 15. Students’ independent work and tasks: Analysis of scientific publications. Writing of summary on particular theme. 16. Learning outcomes: knowledge: On successful completion of the course students will be able to describe reactions of immune response on the process of tumour growth, to provide information on possibilities of immunological diagnosis and immunological treatment possibilities of tumours, the role of immune system in origin and pathogenesis of various allergic diseases, immune diagnosis and possibilities of specific immune therapy of the most common allergic diseases, to describe the impact of several metabolic disorders (protein- Form No M-3 (6) Study Course Description energy malnutrition, obesity, increased carbohydrate load, zinc and iron deficiency) on various immune response reactions and their clinical manifestations. practical skills: On successful completion of the course students will be able to apply the knowledge in acquisition of various compulsory medical courses, diagnostics of various diseases, to distinguish between the most important allergic reactions, to describe the possibilities of their examination and therapy. competence: On successful completion of the course students will be able to apply the knowledge and skills about immunological disorders in diagnostics of various pathologies and development of individual examination plan, to realize the role of immunological changes in the development of various diseases. 17. Type of final examination (examination, semester test, theoretical test, National examination): Test 18. Assessment criteria: • Regular attendance of lectures and practical classes. • Active participation in discussions on the topic discussed during classes and lectures. 19. Readings: Recommended: 1. Roderick Nair, Matthew Helbert. Immunology for medical Students /Second Edition/ – MOSBY Elsevier. 2007. - 308.pp. 2. PeterJ.Delves, Seamus J. Martin, Dennis R.Burton and Ivan M.Roitt ROITT’S Essential Immunology /Eleventh Edition/. Blackwell Publishing. 2006., 2008. 3. Vernera Lozovska redakcijā: Praktiskā alergoloģija /Latvijas Universitāte, 2009/ 4. R.Fuller & G.Perdigion . „Gut flora, nutrition, immunity and health”, Blackwell publishing. 2003. pp 276 5. „Tumor Immunology”in „Immunology” R.Coico @ G. Sunshine 6th ed. WileyBlackwell, 2009.p.299. 6. Mechanisms of tumor immunology” in „Medical Immunology”Tr.Parslow et al. 2006. 11th ed. Lange Medical Book. P.568. Optional: 7. Helen Chapel, Mansen Haeney, Siraj Misbah, Neil Snowden. Essentials of Clinical Immunology, /5-th edition/ – Blackwell. 2006. - 358.pp. 8. Oxford handbook of CLINICAL IMMUNOLOGY AND ALLERGY /Second edition/, edited by Gavin Spickett. 2006. 549.pp. 9. 3. Gerd-Rüdiger Burmester, Antonio Pezzutto, Color Atlas of Immunology. Thieme, 2006. Other sources: Internet sources: http://www.cehs.siu.edu/fix/medmicro/genimm.htm - General immunology Form No M-3 (6) Study Course Description http://www.theimmunology.com/ - General immunology, animation http://cls.umc.edu/COURSES/CLS311/Schd07.doc - Basic and Clinical Immunology Online Course Materials http://www.biology.arizona.edu/immunology/tutorials/immunology/main.html introduction of immunology http://www.immunologylink.com/ - immunology http://www.microbiologybytes.com/iandi/ImmGloss.html - Glossary of Immunology