Beesley 1 Mikala Beesley November 30, 2013 Medical anatomy/physiology 1-2A Bioethics Research of Organ Donation There are several ways that someone could describe organ donation. Organ donation takes healthy organs and tissues from one person for transplantation into another (“Organ donation,” 2013). Often tissue is donated after the person has died, but in some cases a living person can donate organs and tissue for others. Any person can donate organs but if they are under eighteen then they need parents’ permission before donating. Organ donation has been around for a very long time. On December 23, 1954, Dr. Joseph Murray and Dr. David Hume successfully transplanted a kidney from a living patient into his twin brother. In 1962 Dr. Joseph Murray and Dr. David Hume successfully transplanted a kidney from a deceased donor. In 1963 Dr. James Hardy successfully transplanted a lung. In 1966 Dr. Richard Lillehei and William Kelly successfully transplanted a pancreas/kidney. In 1967 Dr. Thomas Starzl successfully transplanted a liver. That same year Dr. Christiaan Barnard successfully transplanted a heart. The transplants have become better and doctors have been able to do more. Technology has made it so much easier to successfully do transplants. Organ donation has come so far that in 2010 a full face transplant took place in Spain (“Transplantation,” 2012) Thus we see organ donation growing. Technology has come very far and has helped organ donation immensely. In 2004 the invention of the life cradle made it so that organs could be preserved for up to 24 hours (Todd, 2008). This gave doctors a little bit of time to find recipients and make the transplant. In the early Beesley 2 years of transplantation there was often the problem of the body rejecting the transplant, but in recent years there haven’t been as many complications because of the advances in medications to suppress the immune system. By using medicine, transplant patients are able to enjoy a longer happier life (Cadena, 2007). Other technological advances include artificial organs. Doctors have made artificial hearts for patients suffering from dilated cardiomyopathy. This condition keeps the hearts left ventricle from contracting properly. Doctors have made battery-powered cardiac assist devises to solve the problem. Another artificial organ is the larynx. It is inserted under the jaw and it generates vibrations in the oral cavity (“Artificial organs: New,” 1999). This makes it so people who have had their larynx removed can talk again. There are increasing options for transplant patients and with years to come there will be even more. There are, however, ethical issues associated with organ donation. “There is rule known as the “Dead-Donor Rule” which states that vital organs should be taken only from persons who are dead. Some people want to donate their organs, but in some cases there is too much time between death and the retrieval of the organs for them to be used. “In another… case the family of a man with devastating brain injury requested withdrawal of life support. The man had been a strong advocate of organ donation, but he was not a candidate for any of the traditional approaches. His family therefore sought permission for him to donate organs before death. To comply with the “Dead-Donor Rule,” plans were made to remove only nonvital organs (a kidney and a lobe of the liver) while he was under anesthesia and then take him back to the intensive care unit, where life support would be withdrawn. Although the plan was endorsed by the clinical team, the ethics committee, and the hospital administration, it was not honored because multiple surgeons who were contacted refused to recover the organs: the rules of the United Network for Organ Sharing (UNOS) state that the patient must give direct consent for living Beesley 3 donation, which this patient's neurologic injury rendered impossible. Consequently, he died without the opportunity to donate. If there were no requirement to comply with the DDR, the family would have been permitted to donate all the patient's vital organs” (Thruog, Miller & Scott, 2013).” The concept of brain death causes some ethical issues as well. Patients meeting the criteria for brain death were originally considered to be dead because they had lost “the integrated functioning of the organism as a whole,” however, it has become clear that patients diagnosed as brain dead have not lost this homeostatic balance but can maintain extensive integrated functioning for years. Brain-dead patients are permanently unconscious and cannot live without a ventilator; therefore recovery of their organs is considered acceptable if organ donation is desired by the patient or by the surrogate on the patient's behalf” (Thruog, Miller & Scott, 2013). Another problem is that the waiting lists are growing larger, and organ donations become a matter of who is at the top of the list. Someone who has been waiting years and needs an organ transplant may have to wait because they aren’t at the top of the list. On the flip side, patients who are at the top of the list may not receive a transplant because the blood type isn’t compatible with theirs. Consequently, the ethical issues sometimes make it hard to receive a transplant. In this case study” the brave toddler Erin Nicks became a transplant record setter just weeks before her third birthday after surgeons at the Birmingham Children’s Hospital gave her a new liver and a new life. Erin, now three, underwent a first liver transplant at the hospital in June 2005 when she was just eight-months-old after doctors diagnosed her as suffering with biliary atresia, a condition which causes bile to build up in the organ. An infection caused her body to reject the liver two years later, but her parents say she is doing well and has a future to look Beesley 4 forward to thanks to her second transplant” (“Organ donation: Erin,” 2013). As a result, we see that organ transplants can save lives! The types of people most often impacted by organ donation are those that need transplants or those who are donating their organs, but everyone can be impacted by organ donation. Any person could be an organ donor, and there are a variety of diseases that cause someone to need an organ transplant. Some diseases are congenital and some aren’t. The frequency that organ donation occurs is daily. People need organs daily, and people die daily and have the opportunity to give their organs to people in need. The most prominent individuals are the ones that are giving and receiving organs. On a scale of 1-10 of the severity of organ donation, I would think, is a 7-8. There are a lot of people that need organs to survive. People die every day waiting to get an organ. People that receive transplants are so grateful because they get to enjoy life with their families. Some people wait years before ever getting a transplant. Yet, there are very few people that are willing to give their organs to others. There are some people that are willing and never get the chance because of laws and still other people who cannot give their organs because of the amount of time they have been deceased. Therefore, the issue of organ donation is increasing. The pros of organ donation are that people with illnesses can survive. If that happened in every case of organ transplantation, then there wouldn’t be a long waiting list, families would be happier, and hospitals would have pride in their work. Babies suffering from organ diseases could be sent home with their parents more often and be free from illness. There wouldn’t be as many sick people waiting for transplants. There would be a hope for everyone that needed a transplant, not doubt. I think the world, altogether, would be a much happier place. Those are things that could happen if the pros of organ donation happened in every case. Beesley 5 The cons of organ donation, is that the body might reject the transplant or that the person might need another transplant later on. If this was the way that all transplants went then it would be very similar to how things are now. People don't always have the most hope in organ donation. No one would get better from their illnesses, no medical treatment would work, and families would be very sad from their losses. I think eventually people would stop seeking medical treatments and spend time with their loved ones before they die. The world would be a sadder place, with no hope for organ transplants. Those are some things that could happen if the cons of organ donation happened all the time. Organ donation is an amazing opportunity to help others live and be with their families. You can help so many people and they are so grateful for the donation. Organ donation saves lives, and the memories of those that died, will live on forever. There have been so many advances in organ donation and there will be more to come. So many lives will be saved by those medical advances. Thus, even with all the ethical issues involved, becoming an organ donator could help someone else live.