Project Concept Note: Animal Breeding and Reproduction Technology Platform Table of Contents 1 Introduction .................................................................................................................................... 3 2 Key Development issues and Rationale for TIA involvement ......................................................... 5 3 Proposed Project Development Objective(s).................................................................................. 7 4 Preliminary Project Description ...................................................................................................... 9 5 Potential Risk and Mitigation ........................................................................................................ 10 1 Introduction The SA commercial livestock industry is highly sophisticated and implements appropriate technologies to ensure good value for the South African consumer. However the industry is no longer able to keep up with local demand and meat imports have been steadily increasing over time. Graph 1 reflects all meat imports between 2001 and 2011, of which 80% is poultry. Graph 2 below shows that SA is also unable to meet the demand for beef. Meat imports into SA (tons) 500000 450000 400000 350000 300000 250000 200000 150000 100000 50000 0 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Year Graph 1: Total meat imports into South Africa between 2001 and 2011 (from Trade Map 2012) Graph 2: Beef Production vs Beef Consumption in SA between 2000 and 2010 (from: ‘A Profile of the SA Beef Market Value Chain 2012’ – DAFF) Currently the livestock sector contributes about 40% of the total value of agricultural output in SA. The data might suggest that livestock production in the country is quite stable, and imports make up for any shortfalls. It is however worthwhile considering some factors on the strategic potential of this sector. It is estimated that almost 80% of the country is considered semi-arid with inadequate or unreliable rainfall to sustain crop production. The South African climate and vast grassland resources are highly suited to livestock production, thus as a country we are not effectively utilising an important competitive advantage. About 40% of the national cattle herd is owned by small-scale rural farmers, yet only 10% of this is reflected in the annual commercial off-take. This would suggest that there is huge potential to improve farming and market systems for small-scale livestock farmers and thereby facilitate socio-economic development. South African indigenous farm animal breeds have not been adequately conserved and risk extinction in some cases. Certain breeds like the boer goat have been used in breeding improvement schemes internationally but are not sufficiently utilised in SA. South African livestock improvement schemes have been running since 1917 and have established an excellent database of phenotypic data. However phenotypic data has not been augmented with genotypic information to update the estimated breeding value system. The livestock industry therefore has not yet benefitted from increased rates of herd improvement that can be achieved from the recent advancements of molecular genetic technologies. In this case we are not adequately leveraging a competitive advantage that the country has strategically invested in over a long period. SA has a competitive advantage in Africa having adapted breeds to prevailing African conditions and pests. As countries in Africa invest in the development of their agricultural sectors, SA can play a strategic role in supplying the African market with appropriate genetic material and technologies. South Africa has the potential to grow the livestock industry significantly and could ultimately become a net exporter of high quality genetic resources, meat, animal products and value-added animal products. The purpose of this document is to discuss the establishment of an Animal Breeding and Reproduction Technology Platform that will provide an institutional framework to facilitate achievement of various objectives to assist the livestock industry as a whole. The initial phase will be to conduct a feasibility study and engage stakeholders on current resources, gaps and priorities for the industry. This document provides a situational analysis, suggests a process to be followed and estimates the costs that would be involved. It is hoped that this will be approved for implementation by TIA EXCO. 2 Key Development issues and Rationale for TIA involvement There are various initiatives underway to support the livestock industry. These include market infrastructure, trade support, veld improvement strategies etc. Solid genetic and breeding capability is the foundation of a strong livestock industry. Thus, the area that TIA will have greatest opportunity to make a meaningful contribution would be in facilitating the establishment of a Breeding and Reproduction Technology Platform. This would be an institutional structure that would prioritize research based on industry needs, leverage funding for research and ensure technology transfer. The discussion below illustrates the current strategies and initiatives underway. The Department of Agriculture, Fisheries and Forestry (DAFF) The Department of Agriculture, Fisheries and Forestry (DAFF) published the Livestock Development Strategy in 2007. The Strategy noted “Research and Development” as a key factor in creating an enabling environment for the industry. It further noted “Biological efficiency of livestock” as a key element. Strategic interventions for that element would concentrate on: Research and Development on sustainable systems for livestock production Reproductive efficiency, growth and development Genetic improvement and enhanced genetic variation Improved efficiency, animal nutrition DNA technology and services Technologies for diagnostics, services and research Integrated livestock and crop systems (especially in communal and resource poor farming areas, e.g. Kwa-Zulu Natal, Limpopo, North West and Eastern Cape), animal health and the management of animal waste Consortium for Genomics in the Livestock Sector In February 2012 key stakeholders from government, academia and industry met to consider “Genomics in the livestock sector”. The participants established an important foundation towards creating a consortium with objectives to: Improve the livestock industry in South Africa through the use of genomic selection to improve the breeding of the animals. Establish the ability and capability of the South African sector to utilise this technology. Develop both national and international collaboration in the field of genomics The consortium also agreed a high level 5-step process for implementing genomic selection Phenotypic data Genotypic data Products/ services Analyse and validate Educate and extend Exploit The National Scheme for Performance Recording Currently selection of breeding lines is based on phenotypic selection and the calculation of Estimated Breeding Values (EBV’s). These values are based on the performance of progeny across certain traits. Performance testing is recognised as a very effective tool for increasing economic returns of livestock production. However it is dependent on the time it takes for each generation to go through reproductive and productive cycles and therefore improvements tend to be seen after significant time investment as demonstrated in Graph 3. Figure 4 : Guernsey - Genetic trends for Milk, Butterfat and Protein Yields 250 8 200 6 150 4 50 0 0 -2 -50 -4 Milk Butterfat Protein -100 -6 -150 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 -10 1986 -250 1985 -8 1984 -200 1983 Milk (kg) Estimated Breeding Values 2 Year of Birth Graph 3: Guernsey – Genetic trends for milk, butterfat and protein yields The Agricultural Research Council (ARC) – Irene has been collating these records since 1917 in the case of dairy cows, and in later years for beef cattle (since 1959), pigs (since 1955) and sheep (since 1965). This database provides the foundation for the National Scheme for Performance Recording for South Africa. Most modern breeding programmes augment phenotypic selection together with genetic selection to calculate Genomic Estimated Breeding Values (GEBV). The GEBV helps to speed up the selection of genetically superior breeding lines. Instead of waiting a minimum of 4 years Artificial Insemination companies can use the best DNA tested as sires of sons as soon as they reach sexual maturity (about 1 year). This is considerable time saving in herd improvement and the benefits of this method have been reported in the Australian, French and American Dairy Cattle Industries. The ARC Molecular Genetics Platform Butterfat and Protein (kg) 100 The ARC has established a molecular genetics platform at their facility in Onderstepoort. The facility has been fully equipped to enable sophisticated molecular genetics research. The facility is to be used by ARC, academic and industry based researchers. The availability of the equipment and expertise makes the operational activities of conducting the necessary research achievable in a relatively short space of time. TIA The livestock industry needs to have access to resources that would enable the effective usage of genetic selection techniques to improve key traits in SA farm animals. However this is a costly and complex activity that needs animal science, molecular biology and computational biology skills to effectively utilise research information. Appropriate technology transfer mechanisms will then need to be deployed and the benefits recovered. TIA through its deep and extensive engagement in the biotechnology sector is ideally positioned to facilitate this. TIA will be able to draw the various stakeholders together to focus objectives, leverage funding to ensure greater investment and promote effective management of the consortium towards technology development and commercialisation. TIA is also an objective facilitator because it is not directly involved in the industry, and agriculture is only one of its multiple areas of investment. TIA would be able to bring together both public and private sector investors and ensure technology diffusion to both public and private sector beneficiaries. TIA, as an organisation, is thus ideally suited to facilitate the establishment of the Animal Breeding and Reproduction Technology Platform. 3 Proposed Project Development Objective(s) The Agri-Biotech sector proposes that an intensive feasibility study be conducted. The investigators will consult all major stakeholders in the private sector, public sector, academia, and in relevant community based structures. An assessment of current resources and gaps in the livestock industry, with respect to genetics, breeding and reproduction, will need to be done. This study will ultimately provide an assessment of the pressing issues facing the sector and suggest an institutional structure and mechanisms to enable the achievement of the objectives. The Business Case for the establishment of the Animal Breeding and Reproduction Technology Platform will be derived from the feasibility study and presented to EXCO. The Animal Breeding and Reproduction Technology Platform, if successful will provide an efficient institutional structure that will: 1) Prioritize research in genetics and animal breeding towards industry needs; 2) Ensure long term improvement and sustainability of the SA livestock industry; 3) Ensure effective transfer of technology from research environments to farmers, processors and retailers; 4) Ensure capacity development, training and skills development programmes are in place to provide for the needs scientific and technical needs of the industry; 5) Provide a financial mechanism for both government and private sector to contribute funding and ensure that funds are used effectively to the benefit of the SA producer and consumer; 6) Have a structured impact analysis capability to ensure that achievements towards the set objectives of the initiative are always monitored and reported to key stakeholders who can then actively direct necessary change. The diagram below suggests that consumer demand for good quality and value will drive the selection process of for research investment within the platform. The outputs of the research will be targeted towards producers who will realise production improvements and be able to deliver towards meeting consumer demand. CONSUMERS DAIRY INDUSTRY BREEDING TECHNOLOGIES FACTORS FARMER / PRODUCER Provide direction on production challenges Provide evaluation on technology performance PRODUCTIVITY FACTORS HIDE PROCESSORS HEALTH FIBRE PROCESSORS FACTORS MEAT PROCESSOR NUTRITION RETAILERS Provide direction on market demands Provide direction on new market opportunities (local/foreign) REPRODUCTIVE TECHNOLOGIES Science councils, Universities, NGO’s Science councils, Universities, NGO’s (molecular techniques, marker assisted breeding) (artificial insemination, embryo transfer, etc.) ARC BIOTECHNOLOGY PLATFORM 4 Preliminary Project Description Feasibility Study Q2 2012/13 Business Case Q4 2012/13 Implementation Q1 2013/14 • Seek TIA EXCO approval to fund benchmarking, industry consultation and feasibility study for the Animal Breeding and Reproduction Platform • Present Business Case on the Animal Breeding and Reproduction Platform to TIA for approval • The initial opertional activities of the Animal Breeding and Reproduction Platform will commence 4.1 Feasibility Study It is proposed that The Animal Breeding and Reproduction Technology Platform will be established to provide academia, government and industry with access to a network of technologies and expertise. This will assist with the strategic development of animal production capability in South Afria, towards meeting expanding local and international market demand for good quality protein sources and other animal products. There is currently limited investment in biotechnology based animal improvement in South Africa. From a TIA perspective the Agri-Biotechnology investment portfolio is heavily skewed towards plant product investments. There is a need to assist the animal production sector by enabling the use of biotechnology tools such as marker assisted breeding and genomic selection towards improving the genetic resource base that farmers utilise. In order to develop an optimal structure, function and operational framework we need to understand the following aspects: 1) What are the international models of best practice and what are the lessons we can learn from them? The EU platform hosted at INRA, France and the Australian Beef CRC have been identified as some of the best models with effective industry participation and leadership. 2) What are the current resources available in SA that will assist this initiative? 3) What are the current gaps in implementing the initiative and how can they be resolved? 4) Who are the major stakeholders, what are their requirements, concerns and potential commitments towards this initiative? 5) What would the Platform’s objectives be? How would these objectives be set, prioritised and reprioritised if necessary? 6) How would the platform operationalize its work and achieve its objectives? What mechanisms will be in place to develop effective strategies to enable industry to set the research priorities such that it delivers research, technologies and products that are demanded by the market? 7) What are the existing structures, programmes and initiatives that the Platform needs to be linked with in order to integrate effectively into the SA livestock production sector? 8) How will the platform invest in technology transfer? 9) Would it be possible to invest in some technologies that already exist or are close to market? In this way technology transfer mechanisms can be implemented, tested and prepared to deliver medium and long term research and development outputs through the most effective mechanisms. 10) What are the impact measures that need to be monitored immediately, in the short, medium and long term to determine if the Platform is indeed achieving its objectives? In order to answer these questions it is proposed that a feasibility study be commissioned. The study will involve benchmarking, gap analysis, stakeholder analysis and discussion of the institutional options that can followed. The study will also make assessments on the funding that will be required to operationalise the platform and present co-financing options. It will have to present both local and international co-funders and donors. The study will also present the criteria for conducting impact assessments on the effectiveness of the Platform once it has been implemented. It is proposed that TIA fund this feasibility in full to the value of R1, 000, 000. The budget is discussed in Section 7 below. 4.2 Business Case The feasibility study will then guide the development of a Business Case. The Business Case will address the issues required by TIA to facilitate the establishment of a platform and follow the required processes to achieve this. It is envisaged that the Business Case will be presented to EXCO during Quarter 4 2012/13. 5 Potential Risk and Mitigation One of the most significant risks faced by the project is that there may be inadequate buy-in from the livestock production industry. If the strategic objectives of the Platform are not carefully developed with full participation of industry and farmers (the potential end users), the Platform risks becoming an academic endeavour as a result, there would be limited beneficial technology transfer opportunities. To prevent this from happening, the various industry players will have to be engaged at the outset and continued participation throughout the feasibility and implementation process will be sought. Industry together with other stakeholders will be consulted in the development of impact assessment measures which will be used to monitor the project and ensure that it does indeed achieve the objectives set by the stakeholders. Furthermore, during the implementation phase industry players will play an important role in prioritising and guiding research activities, thus ensuring direct value of the platform to industry. Another risk that presents during the implementation phase is, whether or not the platform would be able to access adequate funding to run sustainably over a significant multi year period to ensure that appropriate outcomes are achieved. If adequate funding is not available the output and ultimate impact of the Platform would be sorely compromised. This will be mitigated by ensuring substantial industry buy-in and by seeking local and international donor support. We will also involve the best scientists in the industry to lend credibility that would attract the necessary sponsorship. Small-scale farmers are often identified as the beneficiaries of various research and development programmes, yet the consultation and technology transfer processes that are implemented do not facilitate this. Thus the central beneficiaries are completely excluded and technology adoption and diffusion is not achieved. The risk with the Animal Breeding and Reproduction Technology platform is that small-scale farmers may not experience direct benefit. By highlighting the small-scale farmer plight within the objectives of the platform, engaging with organised groups and monitoring and evaluating research and technology output regularly we will be able to mitigate this risk. The Platform would need to develop a position on intellectual property protection in the livestock industry where no specific legal instruments exist in SA to protect genetic improvements. There is potential that much will be achieved within the Animal Breeding and Reproduction Technology Platform but there would be limited protected IP output. Preferred institutional and governance structures that the Platform should clearly reduce financial, regulatory and other risks.