Facilities and Resources
Duke University
Duke University was created in 1924 by James Buchanan Duke as a memorial to his
father, Washington Duke. It consists of 10 schools, with 6,484 undergraduate and 8,107
graduate or professional students. There are 3,262 total faculty and 34,863 employees,
the majority of whom work for the medical center and health system. Duke campus is
located on 939 acres in the city of Durham, NC. The provisions of James B. Duke's $40
million indenture created Duke University's initial endowment. Those funds had a market
value of $5.6 billion in the fiscal year ended June 30, 2012. Patient service revenue
generated by Duke University Health System represented 51 percent of Duke's overall
$4.6 billion in operating revenues in the fiscal year ended June 30, 2012. Other major
revenue sources included: governmental agencies, 13 percent; investment income, 8
percent; tuition and fees (less aid), 8 percent; private grants, 8 percent; auxiliary
enterprises, 4 percent; contributions, 2 percent; Private Diagnostic Clinic, 2 percent;
other, 4 percent. Health care services accounted for the largest portion, 37
percent, of Duke's overall $4.5 billion operating expenditures in fiscal 2012. Instruction
and departmental research accounted for 18 percent and sponsored and budgeted
research for another 16 percent. Other significant operating expenditures included:
general administration, 16 percent; auxiliary enterprises, 4 percent; libraries, 1 percent;
student services, 1 percent; scholarships, fellowships and grants, 1 percent; other, 6
percent.
Duke Medicine
Duke Medicine is an international leader in clinical care, academic research, and
medical education. Duke Medicine strives to transform health care locally and globally
through innovative scientific research and rapid translation of breakthrough discoveries.
Duke Medicine also educates future clinical and scientific leaders, advocates and
practices evidence-based medicine to improve community health, and leads efforts to
eliminate health inequalities.
Duke Medicine integrates the Duke University Health System, the School of Medicine,
and the School of Nursing, as well as faculty from other institutes, centers, and
departments to enable clinical care and life-science research involving a broad range of
populations and diseases across the southeastern United States. The Chief Executive,
who is to be named, is responsible for Duke Medicine, with oversight from the President
Richard Brodhead and the Board of Trustees.
Duke University Health System
The Duke University Health System encompasses Duke University Hospital, Duke
Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke HomeCare &
Hospice, Duke Health and Wellness, and additional affiliates such as the Private
Diagnostic Clinic. Duke University Medical Center was ranked #12 nationally and #1 in
North Carolina by U.S. News & World Report, marking 23 consecutive years that Duke
has been named one of the nation’s best hospitals.
dukemedicine.org
Duke University Hospital
Duke University Hospital, the flagship hospital of the health system, is consistently
ranked among the nation's top hospitals. In the 2013-14 U.S. News & World Report
rankings, it ranked 12th place. It is ranked 1st in North Carolina. As part of the magazine's
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analysis of hospital care, 16 specialties were graded on patient safety, nursing services,
and other care measures. Four of those specialties at Duke made the top 10 in this
year's rankings. The magazine's rankings of Duke medical specialties include:
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Cancer #18
Cardiology & Heart Surgery #6
Diabetes & Endocrinology #23
Gastroenterology & GI Surgery #43
Geriatrics #14
Gynecology #13
Nephrology #11
Neurology & Neurosurgery #25
Ophthalmology #8
Orthopedics #12
Pulmonology #4
Rheumatology #12
Urology #8
Duke University School of Medicine
The Duke University School of Medicine – ranked #8 among medical schools nationwide
– is a premier center for medical education, clinical care and biomedical research. The
School of Medicine is home to 21 academic departments, consisting of more than 2000
faculty members, and the School’s emphasis on collaborative research has resulted in
the development of 12 centers and institutes, including the Duke Clinical Research
Institute and Duke Translational Medicine Institute.
medschool.duke.edu
Duke Translational Research Institute
The Duke Translational Medicine Institute (DTMI) is Duke’s academic home for clinical
and translational research.
DTMI includes investigators and resources across the spectrum of translational
medicine, including discovery, proof of concept, clinical trials, population health studies,
bioinformatics, and implementation into patient care. The DTMI umbrella encompasses
faculty across Duke, including the School of Medicine, School of Nursing, School of
Engineering, Duke Clinical Research Institute (DCRI), Duke Clinical Research Unit
(DCRU), Duke Translational Research Institute (DTRI), and many others.
The DTMI is uniquely focused on translating research into actionable changes in health
care. DTMI fosters collaborations between “bench” scientists and clinical researchers to
rapidly and effectively invent, develop, and test new drug, diagnostics, and devices for
human use.
The DTMI also serves as the coordinating center for the National Patient-Centered
Clinical Research Network (PCORnet), an innovative initiative of the Patient-Centered
Outcomes Research Institute (PCORI). PCORnet aims to improve capabilities in
comparative effectiveness research through the creation of a large, highly representative
network for conducting clinical outcomes research. PCORI supports research that
enables patients to make more informed decisions about their care.
dtmi.duke.edu
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Duke Clinical Research Unit
The Duke Clinical Research Unit (DCRU) is the early phase unit of the Duke Clinical
Research Institute. The DCRU conducts early phase studies, including proof-of-concept,
healthy volunteer studies, and first-in-human studies.
dcru.org
Duke Clinical Research Institute
The Duke Clinical Research Institute (DCRI), part of the DTMI research continuum, is
the world’s largest academic research organization (ARO), combining the services of a
commercial contract research organization (CRO) with the credibility and clinical
expertise of an academic research institute. The DCRI develops and shares knowledge
that improves the care of patients around the world through innovative clinical research.
The DCRI is dedicated to publishing study results regardless of outcome and is
recognized for its thought leadership in study design. From planning to execution to
publishing results, the DCRI’s unique operational model ensures that all aspects of a
project support our dedication to patients and meet the business needs of our sponsors.
By joining skilled project leaders with extensive clinical experience and the country’s top
physician-investigators, our research is tightly focused, efficient, and effective.
dcri.org
The mission of the Health Services and Outcomes Research Group at the Duke Clinical
Research Institute is to lead and advance innovative health services research that
improves the quality, value, and outcomes of patient-centered care.
dcri.org/outcomes
Duke Office of Clinical Research
The Duke Office of Clinical Research (DOCR) supports the School of Medicine Clinical
Research Units (CRUs) (including all faculty, staff, and students) by developing the
“navigation, tools, and training” for the conduct of clinical research in which Duke serves
as an investigative site. The Clinical Research Units (CRUs) are the organizational and
functional structures that provide support for clinical research in which a Duke Medicine
department, center/institute, CSU or school serves as the investigative sites for the
research, or a Duke facility or staff member is responsible for a research activity that
involves intervention or interaction with Duke patients, use of biological specimens from
Duke patients or access to confidential, private information from Duke patients. The
CRU is the operating business unit responsible for oversight including integrity, financial
accountability, regulatory compliance, quality, and academic productivity of clinical
research studies. In 2013, there were more than 4,000 active studies in the Clinical
Research Units at Duke, with 30% funded by industry and 30% funded by the federal
government. The remaining research portfolio is supported by other non-profit
foundations and internal funding.
The DOCR also serves as the home for resources and services for the investigative sitebased research community. The Research Management Team (RMT) is housed within
DOCR. RMT is a valuable resource to investigators at Duke who can seek effort for
designated periods of time for specific tasks – thus, saving monies throughout the life of
the study by using this shared resource instead of hiring and managing for longer
periods (especially during times of development when less work may be needed from
“boots on the ground.”).
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The DOCR is used as a central location for data processing and management.
Vanderbilt University, with collaboration from a consortium of institutional partners, has
developed a software toolset and workflow methodology for electronic collection and
management of research and clinical trial data. REDCap (Research Electronic Data
Capture) data collection projects rely on a thorough study-specific data dictionary
defined in an iterative self-documenting process by all members of the research team
with planning assistance from the DOCR. This iterative development and testing process
provides a well-planned data collection strategy for individual studies. REDCap provides
a secure, web-based application that is flexible enough to be used for a variety of types
of research, provide an intuitive interface for users to enter data and have real time
validation rules (with automated data type and range checks) at the time of entry. These
systems offer easy data manipulation with audit trails and reporting for reporting,
monitoring and querying patient records, and an automated export mechanism to
common statistical packages (SPSS, SAS, Stata, R/S-Plus).
References:
Snyder DC, Epps, S, Beresford HF, Ennis C, Levens JS, Woody SK, Tcheng JE, Stacy
MA, Nahm, M; Research management team (RMT): a model for research support
services at Duke University. Clin Transl Sci, 2012 Dec;5(6):464-9.
Harris PA, Thielke R, Taylor R, Payne J, Gonzalez N, Conde JG. Research electronic
data capture (REDCap)--a metadata-driven methodology and workflow process for
providing translational research informatics support. J Biomed Inform, 2008
Apr;42(2):377-81.
Duke Division of General Internal Medicine
The Duke Division of General Internal Medicine is a Division of the Department of
Medicine. A combined 314 faculty and staff in both clinical and research environments
strive to promote excellence in patient care through new discoveries and improvements
in the practice of primary and internal medicine as well as clinical and behavioral
research that translates to advances and improvements in patient care.
Location: The research division is located at 411 W. Chapel Hill St, Suite 500, Durham,
NC in close proximity to the Duke main campus and Duke University Medical Center and
occupies 8,603 square feet of space with 19 offices, 30 cubicles and 9 additional rooms
(conference rooms, storage, etc.).
Computers/Servers: The computing environment consists of Dell, Lenovo, and Apple
desktops and laptops. All machines are running a minimum of Windows 7/ OSX10.6 or
higher. All machines are licensed to run Office and Symantec Anti-Virus. Per Duke policy
all laptops and mobile devices are to be encrypted with either PGP or Filevault. For
storage purposes, all lab and shared data is housed on our Duke servers currently
running at \\duhsnas-pri\dudom_gim. Dudom_GIM is backed up via the guidelines
below:
Every four weeks a separate backup of the GIM data is captured and retained as a
"monthly" backup in a folder on the central NAS which only administrators have access
to. These snapshots contain a copy of the files from that point in time and are retained
for at least six years.Overall, the backups provide multiple daily snapshots for 30 days
and monthly snapshots for six years.
The General Internal Medicine (GIM) Research Methods and Shared Resources
Core provides essential support for the conduct of clinical research at Duke University.
The Core provides services to support the research and analysis needs of GIM faculty
members and trainees to facilitate high quality study design, grant submissions, and
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post-award study execution for studies focusing on health services and outcomes
research studies being performed by faculty members and trainees within the Division.
The Core includes two units for charging purposes: 1) Research Services Personnel
Unit: This Unit facilitates faculty members’ access to staff with appropriate expertise in
the conduct of patient oriented clinical research studies (single or multi-site). The unit
facilitates the efficient and sustained use of expert staff to enhance the conduct of
clinical research studies. Staff employed by the core have expertise in the conduct of: a)
Coordination, recruitment, data collection, and participant tracking for trials of patient
oriented interventions; b) data collection and analysis for observational studies; and, c)
recruitment, data collection, and analysis of qualitative studies. The unit also provides
guidance regarding: a) best practices in research study protocol development and
methods to meet research regulatory and data safety requirements (e.g., IRB application
approvals and identifying and conducting Data Safety Monitoring Boards); b) intervention
development; c) study participant tracking; d) data collection, storage and management;
e) hiring part time students or staff to support research; and f) grant submission. 2)
Computer, Analytic and Server Unit: The core provides a broad range of fundamental
resources for patient oriented clinical researchers including: a) research study specific IT
maintenance/management (e.g., personnel support to ensure appropriate computing
infrastructure to carry out study aims); b) identifying and obtaining appropriate study
specific computer hardware/software; c) providing study specific file/data storage; d)
ensuring studies have appropriate daily backup/archival/encryption procedures in place;
e) providing software licensing/updating fees; and, f) providing access to virtual servers
for analysis as appropriate.
Location: The Core is located within the Division of General Internal Medicine, 411 W.
Chapel Hill St, Suite 500, Durham, NC. This location is ideal as it is in very close
proximity to a majority of health services, implementation science and outcomes
researchers within the Division who would be most likely to utilize the resources.
Department of Biostatistics and Bioinformatics
The Department of Biostatistics and Bioinformatics (B&B) engages in methodological
and collaborative research, and directs three educational degree programs: the Clinical
Research Training Program (CRTP), the Master of Biostatistics Program, and the PhD
Program. Instructors in these programs, as well as other faculty members in the
department, either teach courses or supervise student research in the areas of
biostatistics, computational biology, statistical genetics, epidemiology, health economics,
health services research and computational medicine.
The Department currently has over 50 faculty members who are individually affiliated
with various research groups, centers, and institutes across the School of Medicine,
including the Duke Clinical Research Institute, the Institute for Genome Sciences and
Policy, the Duke Cancer Institute, the Durham VA Medical Center, the Center for
HIV/Aids Vaccine Immunology, and the Duke Center for Aging. The discipline of
biostatistics constitutes a primary focus of the Department, which serves as the
academic home for faculty biostatisticians in the Medical Center.
Outside the School of Medicine, statistics and biostatistics are represented at Duke by
the Department of Statistical Science, one of the eight natural science departments in
the School of Arts and Sciences. Some Department of Statistical Science faculty
members have secondary appointments in B&B, and vice-versa. Secondary
appointments are also held by several faculty members in the Center for Human
Genetics whose primary appointments are in the Department of Medicine.
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Duke Health Technology Solutions
Duke Health Technology Solutions (DHTS) provides the overarching information
technology solutions for Duke Medicine. With over 600 employees, DHTS’s assets and
services include the enterprise data center, enterprise service desk, and comprehensive
network and hardware support. It serves over 11,000 administrative, clinical and
financial customers. DHTS manages over 6,000 computers for departments throughout
Duke University Health System in a twenty-four hour/seven day support structure. In
addition, the team also includes individuals that specialize in database development,
network administration, workstation support, IT security, project and consultative
services and web technologies.
The DHTS Academic Device Support Team consists of 23 IT analysts; dedicated to
hardware, software, and supporting infrastructure for end-user computers in a multiplatform environment, Windows, Mac and Linux. The base image is deployed to Duke
purchased hardware and departmental sanctioned hardware, with Windows, Mac and
Linux current operating system. Support is focused on School of Medicine research
faculty and administrative support, in a departmental unit.
Center for Health Services Research in Primary Care
The Center for Health Services Research in Primary Care is a national leader for
creative, high-quality health services research studies designed for the benefit of
American adults. The Center's objective is to develop strategies that enhance the
delivery, quality, and cost-efficiency of primary care among adults. The Center’s blend of
Epidemiology, Health Services Research, Biostatistics and Behavioral approaches has
led to significant NIH funding for interdisciplinary research aimed at defining effective
approaches to implementing therapeutic strategies for chronic diseases important to
primary care. The Center provides full service infrastructure for 18 physician and 14 PhD
investigators conducting complex interventional studies that inform new models of health
care delivery in the primary care setting. The PhD staff provides expertise in
biostatistics, epidemiology, health policy, psychology, and sociology. Physician research
associates provide expertise in areas such as medical decision making and translating
evidence-based guidelines into practice as well as provide research links to clinical
disciplines, such as: general internal medicine, endocrinology, geriatrics, infectious
disease, gastroenterology, cardiology, neurology, ophthalmology, psychiatry, and
rehabilitative medicine. Faculties in this Center are currently engaged in over 100 funded
research projects totaling over $38 million. The Center maintains close organizational
ties with the VHA and the Durham VAMC. It also maintains academic affiliations for
teaching and research collaborations with Duke University and the University of North
Carolina at Chapel Hill. The Center began research activities in October 1982.
Multicultural Resource Center
The Multicultural Resource Center (MRC) assists all centers, departments, and institutes
in the School of Medicine. The MRC was established to help the medical school achieve
and maintain a position of cultural competency in medical education, thereby assisting
with the preparation of students, staff, and faculty to work and live in a world of diverse
people from diverse backgrounds. The MRC is directed by Maureen Cullins, is under
direct supervision by the dean of the medical school, and comprises three initiatives:
multicultural health initiatives, community health initiatives, and minority faculty
development. This center serves as a repository of information on fellowships, grants,
clinical programs, research opportunities, externships, and scholarships. The center also
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focuses on issues of institutional climate, mentoring, recruitment, and retention.
MRC staff works with faculty to design cultural competency education--training to help
students provide culturally sensitive care to patients of different ages, races,
nationalities, and socioeconomic backgrounds. The center presents special events to
promote understanding of the impact of race and culture on health care, such
as a "Race in Medicine," "Spirituality and Health," and "Gender and Sexuality and
Health." The medical school community also benefits from the MRC Visiting Professor
Lectures, which provide education and context for the larger issues that impact patients
and patient care. Experiential learning is supported by the Charles Watts Travel Fund
and the MRC Opportunity Fund. These awards promote cultural competence by
providing financial support to apply what is learned in the classroom in an environment
outside the traditional medical school setting.
Department of Psychiatry and Behavioral Sciences
The Department of Psychiatry and Behavioral Sciences has evolved into a major hub of
multidisciplinary clinical research with over 400 faculty. These programs range from a
large effort in nanotechnology to health services research. The faculty comes from many
diverse backgrounds including Health Policy, Experimental Psychology, Behavioral
Medicine, Psychiatry, and cognitive neuroscience. Approximately 270 individual clinical
research studies are conducted each year through the Department of Psychiatry and
Behavioral Sciences. Strong clinical and research programs are focused on
schizophrenia, affective disorders, alcohol and addictions, anxiety disorders, behavioral
medicine, childhood disorders, and other clinical populations. The Department
consistently ranks among the top five to ten departments in the country in NIHsponsored research and is a leader in industry-sponsored trials.
Duke University School of Nursing
The Duke University School of Nursing advances nursing science, promotes clinical
scholarship, and educates clinical leaders, advanced practitioners, and researchers. The
School of Nursing is ranked #7 nationally by U.S. News & World Report.
nursing.duke.edu
Duke University Library System
With more than 5 million volumes, the Duke University Library System is one of the ten
largest private university library systems in the United States. The Medical Center
Library has recorded holdings of 270,000 volumes and 2,700 periodicals and has
professional reference service available as well as a self-service networked electronic
database, which is wired, through the Medical Center. The Medical Center’s Division of
Audiovisual education provides services for teaching research and patient care
programs. The Division’s services include Medical Art, Medical Photography, Central
Televisions, Computer Graphics, Instructional Design, and Teleconferencing capabilities.
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