Position within the Project: Director
1. Last name: REGNARD
2. First name: Jean-François
Date and place of birth: 21 June 1953, France
3. Citizenship: French
4. Marital status: married
5. Education:
Institution
Period
Degrees or diplomas
Medical School at Paris VII 1975-1981
University
Medical Doctor, Paris School
of Medecine Laureat, Silver
Medal
6. Professional experience:
Institution
Position
Description
Medical School, Paris 1983 - 1985
XI University ParisSud
Medical School, Paris 1985 - 1987
VII
University
Bichat-Beaujon -
Assistant professor
Thoracic
activity
surgery
Assistant professor
Thoracic
activity
surgery
Marie Lannelongue 1987 - 1991
Surgical Center
Marie Lannelongue 1991 - 2000
Surgical Center
Hôtel-Dieu Hospital
2000- today
Surgeon
Hôtel-Dieu Hospital
Period
2000- today
Thoracic
surgery
activity
Deputy Chief on duty, Managerial activity
Thoracic Service
Professor
Medical
School
courses for students
Head of Thoracic Managerial activity
Service
Management experience
Equipment Commission in Marie Lannelongue Surgical Center
Anti-Nosocomial infection Comitee in Marie Lannelongue Surgical Center
Elected member of Medical Commission in Marie Lannelongue Surgical Center
Member in Medical Consultative Council at Hôtel-Dieu Hospital
Ministry and Administration expertises, missions and studies
 Overhaul of Thoracic Surgery Acts Nomenclature (1998)
 Overhaul of Surgery Acts Nomenclature: between specialties (1998)
 « Standards, Options and Recommendations’ » for the care of patients with thymus epithelial tumors
(1999)
 Study of life quality of patients aged 70 and over, with pulmonary resection for lung cancer (2000)
 Surgery and Cancer (National Cancer Plan) – Regional Agency of Hospitals 2005
 Standards, Options and Recommendations’ » for peri-operative treatment of patients with operable
non-small lung cell cancer (2007)
 « Volume Centre Impact in Thoracic Surgery» - Regional Agency of Hospitals 2007
 Medical Leadership: « Thoracic Surgery Group: Summary and Recommendations» (2008)
 Ile de France Pneumologists College "Strategic evolutions in chest medicine to Public Hospitals of
Paris " (document prepared by the Medical Chest College of Ile de France in collaboration with the
thoracic surgeons of Public Hospitals of Paris) (2008)
7. Foreign languages: English
8. Patents, if applicable (maximum 5):
9. Publications, if applicable (maximum 5, the most relevant to the project domain):
1. Prediction of clinical outcome in multiple lung cancer cohorts by integrative genomics : implications
for chemotherapy selection : P. Broët, S. Camilleri-Broët, S. Zhang, M. Alifano, D.D. Bangarusamy, M.
Battistella, Y.H. Wu, M. Tuefferd, J.F. Régnard, E. Lim, P. Tan, L. Miller Cancer Res 2009;69(3):1055-62
2. Neurotensin expression and outcome of malignant pleural mesothelioma : M. Alifano, M. Loi, S.
Camilleri-Borët,
S.
Dupouy,
J.F.
Régnard,
P. Forgez Thorax (soumis)
3.Effects of neurotensin receptor-1 activation on non-small cell lung cancer grouwth and outcome : M.
Alifano,
F.
Souazé,
S.
Dupouy,
S. Camilleri-Broët, F. Broët, L. Miller, C. Gespach, J.F. Régnard, P. Forgez
Cancer Res (soumis)
4.Peroperative frozen section analysis of ttf-1 antigen expression: S. Camilleri-Broët, M. Alifano, M.
Morcos,
E.
Comperat,
P.
Magdeleinat,
B. Marmey, T.J. Molina, J.F. Régnard, J. Audouin J Clin Pathol 2004;57(1):98-100
5.variable sensitivity and specificity of ttf-1 antibodies in lung metastatic adenocarcinoma of colorectal
origin : E. Compérat, F. Zhang, C. Perrotin, T. Molina, P. Magdeleinat, B. Marmey, J.F. Régnard, J.
Audouin, S. Camilleri-Broët Mod Pathol 2005;18(10):1371-6
10. Member of professional associations:
 General
Secretary
of
French
Thoracic
and
Cardio-Vascular
(1990 – 1995)
 French Thoracic and Cardio-Vascular Society
 Thoracic Surgery and Cardio_Vascular College
 French Pneumology Society
 European Association of Cardio-Thoracic Surgery
 Member of Scientific Council of the Thoracic Oncology French Intergroup
Society
11. Specializations and qualifications:
Fellowship MAYO CLINIC Thoracic Surgery(Rochester) (Dr PAIROLERO)- 1995
Fellowship MEMORIAL SLOAN KETTERING CANCER CENTER (Dr GINSBERG)-1998
Reviewer:
 French :
- Annales de Chirurgie
- Journal de Chirurgie Thoracique et Cardio-Vasculaire
- Revue des Maladies Respiratoires
 Foreign:
- Annals of Thoracic Surgery
- European Journal of Cardio-Thoracic Surgery
12. Experience (including managerial experience) in other national/international programmes/
projects:
Programme/project
Position
« Medical and Economic Coordinator
evaluation of FOREseal
innovation versus surgical
adhesives in terms of duration
of air leaks after lung resection
settled requiring mechanical
stapling».
Period
(STIC - 2009)
15. List of the most important publications/patents (only for the international expert):
1.LOBECTOMY WITH PULMONARY ARTERY RESECTION : MORBIDITY, MORTALITY, AND
LONG-TERM SURVIVAL : M. Alifano, G. Cusumano, S. Strano, P. Magdeleinat, A. Bobbio, F. Giraud,
B. Lebeau, J.F. Régnard J Thorac Cardiovasc Surg (doi:10.1016/jtcvs.2008.11.002) [in press]
2.NONINVASIVE VENTILATION FOR ACUTE RESPIRATORY FAILURE AFTER LUNG
RESECTION : AN OBSERVATIONAL STUDY : A. Lefebvre, C. Lorut, M. Alifano, H. Dermine, N.
Roche, R. Gauzit, J.F. Régnard, G. Huchon. A. Rabbat Intensive Care Med 2008 Oct 14. [Epub ahead of
print]
3. A NEW METHOD FOR DETECTION OF POSTPNEUMONECTOMY BRONCHO-PLEURAL
FISTULA : M. Alifano, S. Sepulveda, A. Mulot, O. Schussler, J.F. Régnard Ann Thorac Surg
2003;75(5):1662-4
4.RESULTS OF SUPERIOR VENA CAVA RESECTION FOR LUNG CANCER. ANALYSIS OF
PROGNOSTIC
FACTORS
:
L.
Spaggiari,
P.
Magdeleinat,
H.
Kondo,
P. Thomas, M.E. Leon, G. Rollet, J.F. Régnard, R. Tsuchiya, U. Pastorino Lung Cancer 2004;44(3):33946
5.PERICARDIAL ECTOPIC THYMOMA (Case Report) : S. Azoulay, C. Adem,
M. Gatineau, J.F. Finet, H. Bakdach, J.F. Régnard, F. Capron Virchows Arch 2005;446(2):185-8
6.CATAMENIAL
PNEUMOTHORAX
:
SOME
COMMENTARIES
:
M.
Alifano,
P. Magdeleinat, J.F. Régnard J Thorac Cardiovasc Surg 2005;129(5):1199. Authors Reply 1199-200
7.EARLY AND LONG-TERM RESULTS OF LUNG RESECTION FOR NON-SMALL-CELL LUNG
CANCER
IN
PATIENTS
WITH
SEVERE
VENTILATORY
IMPAIRMENT
:
P. Magdeleinat, A. Seguin, M. Alifano, S. Boubia, J.F. Régnard Eur J Cardiothorac Surg
2005;27(6):1099-1005
8.PREOPERATIVE ANALYSIS OF BIOPSIES ISSUED FROM MEDIASTINOSCOPY : M. Alifano,
M. Morcos, S. Camilleri-Broët, P. Magdeleinat, J.F. Régnard Surg Endosc 2005;19(11):1456-9
9.RESECTION FOR TUMORS WITH CARINAL INVOLVEMENT. TECHNICAL ASPECTS,
RESULTS AND PROGNOSTIC FACTORS : J.F. Régnard, C. Perrotin, R. Giovannetti, O. Schussler, A.
Petino, L. Spaggiari, M. Alifano, P. Magdeleinat Ann Thorac Surg 2005;80(5):1841-6
10. AN UNUSUAL OF HICCUP : COSTAL EXOSTISIS. TREATMENT BY VIDEO-ASSISTED
THORACIC SURGERY : M. Alifano, M. Morcos, T. Molina, J.F. Régnard
Eur J Cardiovasc Surg 2003;23(6):1056-8
11.VARIABLE SENSITIVITY AND SPECIFICITY OF TTF-1 ANTIBODIES IN LUNG
METASTATIC ADENOCARCINOMA OF COLORECTAL ORIGIN : E. Compérat, F. Zhang, C.
Perrotin, T. Molina, P. Magdeleinat, B. Marmey, J.F. Régnard, J. Audouin, S. Camilleri-Broët
Mod Pathol 2005;18(10):1371-6
12. SURGICAL TREATMENT OF SUPERIOR SULCUS TUMORS : RESULTS AND PRONOSTIC
FACTORS : M. Alifano, M. D’Aiuto, P. Magdeleinat, E. Poupardin, A. Chafik, S. Strano, J.F. Régnard
Chest 2003;124(3):996-1003
13. SUPERIOR VENA CAVA RESECTION WITH PROSTHETIC REPLACEMENT FOR NONSMALL CELL LUNG CANCER : LONG-TERM RESULTS OF A MULTICENTRIC STUDY : L.
Spaggiari, P. Thomas, P. Magdeleaint, H. Kondo, G. Rollet, J.F. Régnard.
R. Tsuchiya, U. Pastorino Eur J Cardiothorac Surg 2002;21(6):1080-6
14.THE PLACE OF ROUTINE IMMEDIATE NON-INVASIVE VENTILATION FOLLOWING
PULMONARY RESECTION IN PREVENTING PULMONARY COMPLICATIONS IN PATIENTS
WITH COPD (POPVNI TRIAL) : C. Lorut, A. Rabbat, G. Chatelier, A. Lefevre, N. Roche, J.F. Régnard,
G. Huchon Rev Mal Respir 2005;22(1 pt 1):127-34
15.POSTOPERATIVE
PNEUMONIA
AFTER
MAJOR
LUNG
RESECTION :
O. Schussler, M. Alifano, H. Dermine, S. Strano, A. Casetta, S. Sepulveda, A. Chafik,
S.. Coignard, A. Rabbat, J.F. Régnard Am J Respir Crit Care Med 2006;173:1161-9
16.THORACIC ENDOMETRIOSIS : CURRENT KNOWLEDGE : M. Alifano, R. Trisolini, A.
Cancellieri, J.F. Régnard Ann Thorac Surg 2006;81(2) 761-9
17.LIFE-THREATENING ENDOMETRIOSIS-RELATED HEMO-PNEUMOTHORAX : A CASE
REPORT : M. Morcos, M. Alifano, T. Molina, J.F. Régnard Eur J Cardiothorac Surg 2006;82:726-9
18.LE
MESOTHELIOME
PLEURAL
MALIN.
PLACE
DE
L’EXERESE
CHIRURGICALE : R. Giudicelli, J.F. Régnard, P. Astoul, P. Ruffié Rev Mal Respir 2006;23:105-6
19.DIFFICULT MANAGEMENT OF RECURRENT CATAMENIAL PNEUMOTHORAX : P. Oger,
M. Alifano, J.F. Régnard, A. Gompel Gynecol Endocrinol 2006;22:713-5
20.CARCINOMA SHOWING THYMUS-LIFE ELEMENTS (CASTLE) INVADING THE TRACHEA :
M. Alifano, M.S. Boudaya, C. Dinu, H. Kadiri, J.F. Régnard J Thorac Cardiovasc Surg 2006;132:191-2
21.HEMOTHORAX AS THE CLINICAL PRESENTATION OF A PANCREATICO-PLEURAL
FISTULA : REPORT OF A CASE : M.S. Boudaya, M. Alifano, S. Baccari,
J.F. Régnard Surg Today 2007;37(6):518-20
22.CATAMENIAL
AND
NONCATAMENIAL,
ENDOMETRIOSIS-RELATED
OR
NONENDOMETRIOSIS-RELATED PNEUMOTHORAX REFERRED FOR SURGERY : M. Alifano,
C. Jablonski, H. Kadiri, P. Falcoz, A. Gompel, S. Camilleri-Broët, J.F. Régnard Am J Respir Care Med
2007;176(10):1048-53
23.ENDOBRONCHIAL SCLEROSING HEMANGIOMA : A RARE PRESENTATION OF A
PARENCHYMAL TUMOR : M.S. Boudaya, P.E. Falcoz, M. Alifano, S. Camilleri-Broët, J.F. Régnard
Asian Cardiovasc Thorac Ann 2008;16(1):57-8
24.PNEUMONECTOMIES AFTER CHEMOTHERAPY : MORBIDITY, MORTALITY AND LONGTERM RESULTS : M. Alifano, M.S. Boudaya, M. Salvi, J.Y. Collet, C. Dinu, S. Camilleri-Bröet, J.F.
Régnard Ann Thorac Surg 2008;85:1866-73
25.SURGICAL TREATMENT OF BRONCHIECTASIS : EARLY AND LONG TERM RESULTS : R.
Giovannetti,
M.
Alifano,
A.
Stefani,
A.
Legras,
M.
Grigoroiu,
J.Y.
Collet,
P. Magdeleinat, J.F. Régnard Interact Cardiovasc Thorac Surg 2008;7:609-12
26.SHOULD WE CHANGE ANTIBIOTIC PROPHYLAXIS FOR LUNG SURGERY ?
POSTOPERATIVE PNEUMONIA IS THE CRITICAL ISSUE : O. Schussler, H. Dermine, M. Alifano,
A.
Casetta,
S.
Coignard,
N.
Roche,
S.
Strano,
A.
Meunier,
M.
Salvi,
P. Magdeleinat, A. Rabbat, J.F. Régnard Ann Thorac Surg 2008;80(6):1727-33
I hereby state on my own responsibility that the data presented is accurate.
Date: 08.06.2009