Ian Goodfellow
Noroviruses and Molecular Virology
Often referred to as ‘winter-vomiting disease’, noroviruses are a major cause of gastroenteritis
worldwide and frequently cause the closure of hospital wards in the UK. Best estimates suggest that
23 million cases of norovirus gastroenteritis occur in the US and >1 million cases UK each year.
Despite the significant impact of noroviruses, progress on understanding the molecular mechanisms
of virus replication and progress towards methods of either preventing or controlling outbreaks has
been limited.
Our lab uses a combination of diagnostic, molecular and biochemical approaches to gain a better
understanding of the prevalence and biology of noroviruses (and other related RNA viruses), and to
identify methods of controlling or preventing outbreaks of these economically important pathogens.
Clinical specialties our work is relevant to: Infection and immunity.