LONDON METROPOLITAN UNIVERSITY
Module Specification template
Section One: ABOUT THE MODULE
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Module title
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Module code
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Module level and credit rating
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Faculty
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School/Subject Discipline
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Teaching locations
northnorth
Toxicology
BM7112DL
Level 7Level 7
1010
Life SciencesLife Sciences
School of Human SciencesSchool of Human Sciences
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DayDay
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Teaching period
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Pattern of attendance
Required prior learning
Module description
BM7112DL
Introduction to Toxicology
This module provides information and guidance to faciliatate an indepth understanding and knowledge
of the theory and practical applications of toxicology. It explains the underlying mechanisms of
xenobiotic (drug) metabolism and enables these ideas to be expanded to the understanding of human
health and disease.
Semester: Autumn, Spring, Summer (10 credit)
Required prior Learning:
Assessment: Quizzes (300 words)(30%), reflective learning log (750 words)(30%), coursework (1000
words)(40%)
Module aims
The aims of this module are aligned with the qualification descriptors within the Quality Assurance
Agency’s Framework for Higher Education Qualifications. To provide, through in depth study,
knowledge and understanding of the theory and practice of toxicology and to reinforce analytical,
evaluative and communication skills. Additionally to research a topical issue in depth and present it at
an appropriate level and to reflect on the topics studied and their application in biomedical,
pharmaceutical or forensic practice.
Module learning outcomes
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On successful completion of this course students will be able to:
1. Describe the scope of toxicology, in particular the key roles of absorption, distribution, metabolism
and excretion as determinants of toxicity.
2. Relate toxicology theory to laboratory, clinical and forensic practice, including awareness of factors
affecting sample integrity, sample clean-up procedures and limitations of analysis.
3. Demonstrate understanding of key aspects of toxicology inter alia drug metabolism, free radical
biochemistry, tests for toxicity, structure-function relationships and the detection of toxic substances in
bulk and in biological matrices.
4. Understand principles of quality control and quality assurance in relation to toxicology and critically
interpret and evaluate information from a particular case study.
5. Demonstrate through the reflective learning journal that the student has reflected on their own
performance as an independent professional learner.
Indicative syllabus – for full details see section C in Module Booklet
This module provides an understanding and knowledge of the theory and practice of toxicology
It will include an introductory background to toxicology, scope of subject, central role of drug or xenobiotic
metabolism is determining toxicity, methods for establishing levels of toxicity, techniques of measurement
including HPLC, GC and coupled mass spectrometric detection. Application of the principles to the
understanding of specific toxicities inter alia ethanol, paracetamol, carbon monoxide, ethylene glycol,
redox-cycling drugs.
Indicative bibliography and key on-line resources – for full details see section D in Module Booklet
Hodgson E (2010) A textbook of Modern Toxicology, 4th Ed. Wiley.
Lu FC (2003) Lu’s Basic Toxicology, 4th Ed. Taylor and Francis.
Timbrell JA (2002) Introduction to Toxicology, 3rd Ed. Taylor and Francis.
Timbrell JA (2009) Principles of Biochemical Toxicology, 4th Ed. Informa Healthcare.
Learning and Teaching strategy for the module including approach to blended learning, students’ study
responsibilities and opportunities for reflective learning/pdp
Information pertaining to the subject matter will be presented through an integrated programme of
lectures and supporting exercises, together with some use of a problem-based learning approach and
the guided use of student-centred learning resources. Lectures will be used to provide a conceptual
framework. Student centred assignments will enable students to reinforce and expand their
knowledge, and develop subject specific skills and competence.
Indicative learning and teaching hours for the module. Learning hours comprise face-to-face and virtual
contact hours plus self-managed and directed learning and time spent on placements (where relevant).
Method
Description and percentage of learning hours
Scheduled learning and teaching activities
Guided independent study
100 (100%)
TOTAL LEARNING HOURS FOR THE
100
MODULE
Assessment strategy
The module will be formatively assessed by in-course online quizzes (30%) and two coursework
components. A reflective learning log (750 words)(30%) and a written assignment (40%; 1000 words).
Criteria for assessment will include an understanding of the subject matter; an ability, both orally and
written, to explain, describe and discuss the work; completeness and conciseness of written reports
and essays with emphasis upon critical ability and scientific rigour. To pass the module students need
to achieve a minimum aggregate mark of 50%.
Component
Learning outcomes
Quizzes
1,2
Reflective learning log
3,4,5
Written assignment
3,4,5
Arrangements for formative and summative feedback
Written feedback on the coursework will be given at the end of the module
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Description of assessment items
Assessment
Method
Practical
ExamPractical
Exam
CourseworkCour
sework
CourseworkCour
sework
Description of Item
%
weighting
Week
Due
On-line Quizzes (300 words)
30
Reflective learning log (750 words)
30
12
Written assignment (ECA) (1000 words)
40
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Section Two: FACULTY USE
20 Nominated External Examiner
21 Nominated Module Leader at time of approval
22 Courses to which this module contributes and
whether Core or Option
If not pass on aggregate,
explain what is required to
pass the module
Dr Neville Hall
Dr Andrew Searle
Section Three: OFFICIAL USE AND CODES – responsibility for completion is as indicated
23 Original date of approval (QEU)
24 Module approved to run from (QEU)
25 Revision date (specify cohort) (QEU)
26 Module specification version number (QEU)
27 SITS Mark Scheme (Academic Registry)
28 Subject Standards Board Name (Academic
Registry)