8950255_187006_CV-Hanson-Jan-2016

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MARTIN GARTZ HANSON, PH.D.
(216) 262-4050  gartz.hanson@gmail.com
RESEARCH SCIENTIST
Trusted, motivated and respected research scientist with a significant history of meaningful research in
neuroscience and developmental biology. My experience combines electrophysiological, pharmacological,
cell culture, molecular and translatable approaches to understand diseases of development. My mission
is to combine basic and translational sciences in an industry setting.
AREAS OF EXPERTISE AND RESPONSIBILITIES

Managed multi-functional groups of scientists and collaborators using basis science and
translational approaches in parallel projects.

Designed, performed and analyzed experiments for various published rodent neuroscience
projects.

Designed and executed in vivo biomarker studies for therapeutic relevance.

Developed neurodegenerative disease models using rodent explant and cell cultures.

Independently innovated assays for imaging and pharmacology.

Proposed novel targets and strategies for metabolic and neurodegenerative diseases.

Managed external resources in a meticulous manner to best achieve scientific and laboratory
goals.
PROFESSIONAL EXPERIENCE
UNIVERSITY OF COLORADO, Aurora, CO
CONSULTANT, Department of Cell and Developmental Biology
2015 +
UNIVERSITY OF COLORADO, Aurora, CO
RESEARCH ASSOCIATE, Pediatrics Department
2014 to 2015
HOWARD HUGHES MEDICAL INSTITUTE, Aurora, CO
RESEARCH SCIENTIST, Pediatrics Department
2011 to 2014
UNIVERSITY OF COLORADO, Aurora, CO
POSTDOCTORAL FELLOW, Pediatrics Department
2005 to 2011
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH
POSTDOCTORAL FELLOW, Neurobiology Department
2004 to 2005
STANFORD UNIVERSITY, Palo Alto, CA
RESEARCH TECHNICIAN, Neuroscience Department
1994 to 1998
E DUCATION
Ph.D. in Neuroscience 2004
Case Western Reserve University, Cleveland, OH
Bachelor of Arts in Biology 1993
Central Methodist University, Fayette, MO
M. GARTZ HANSON, PH.D.
(216) 262-4050  GARTZ.HANSON@GMAIL.COM  page 2
PUBLICATIONS
Research Articles

Ebens, A., Brose, K., Leonardo, E. D., Hanson, M. G., Jr., Bladt, F., Birchmeier, C., Barres, B. A., and
Tessier-Lavigne, M. (1996). Hepatocyte growth factor/scatter factor is an axonal chemoattractant
and a neurotrophic factor for spinal motor neurons. Neuron 17, 1157-72.

Hanson, M. G., Jr., Shen, S., Wiemelt, A. P., McMorris, F. A., and Barres, B. A. (1998). Cyclic AMP
elevation is sufficient to promote the survival of spinal motor neurons in vitro. J. Neurosci 18, 736171.

Meyer-Franke, A., Wilkinson, G. A., Kruttgen, A., Hu, M., Munro, E., Hanson, M. G., Jr., Reichardt, L. F.,
and Barres, B. A. (1998). Depolarization and cAMP elevation rapidly recruit TrkB to the plasma
membrane of CNS neurons. Neuron 21, 681-93.

Hanson M.G. and Landmesser L.T. (2003) Characterization of the circuits that generate spontaneous
episodes of activity in the early embryonic mouse spinal cord. J Neurosci. 2003 23, 587-600.

Hanson, M. G., and Landmesser, L. T. (2004). Normal patterns of spontaneous activity are required
for correct motor axon guidance and the expression of specific guidance molecules. Neuron 43, 687701.

Christopher P. Myers, C.P, Lewcock, J.W., Hanson, M. G., Gosgnach, S, Aimone, J.B., Gage, F.H., Lee, KF, Landmesser, L. T, and Pfaff, S.L. (2005) Cholinergic input is required during embryonic
development to mediate proper assembly of spinal locomotor circuits. Neuron. 46:37-49.

Li X, Gutierrez D.V., Hanson M.G., Han J, Mark M.D., Chiel H, Hegemann P, Landmesser L.T., Herlitze S
(2005) Fast noninvasive activation and inhibition of neural and network activity by vertebrate
rhodopsin and green algae channelrhodopsin. Proc Natl Acad Sci. 102:17816-21.

Hanson M.G, Landmesser L.T. (2006) Increasing the frequency of spontaneous rhythmic activity
disrupts pool-specific axon fasciculation and pathfinding of embryonic spinal motoneurons. J
Neurosci. 26:12769-80.

Hanson M.G., Fregoso V.L., Vrana J.D., Tucker C.L., Niswander L.A. (2014) Peripheral nervous system
defects in a mouse model for peroxisomal biogenesis disorders. Dev Biol. 2014 Nov 1;395(1):84-95.

Hanson M.G. and Niswander L.A. (2014) An explant muscle model to examine the refinement of the
synaptic landscape. J Neurosci Methods. 2014 Dec 30;238:95-104.

Hanson M.G., Wilde J.J., Moreno, R.l. Minic, A.D., Niswander L.A. (2015) Potassium dependent rescue
of a myopathy with core-like structures in mouse. eLife Jan 7; 4.

Hanson M.G and Niswander L.A. (2015) Rectification of muscle and nerve deficits in paralyzed
ryanodine receptor type 1 mutant embryos. Dev Biol. 2015 DOI:10.1016/j.ydbio.2015.05.018

Hanson M.G., Aiken J., Sietsema D., Sept D., Niswander L.A. , Moore J.K. (2015) Novel α-tubulin
mutation disrupts neural development and microtubule stability. (Accepted Dev. Bio. Nov. 2015)

Moreno R.L. and Hanson M.G. (2015) Ryanodine receptor type 3 is involved in removal of
postsynaptic neuromuscular junctions during development and disease. (Submitted to PlosOne Dec.
2015)
Reviews

Hanson, M.G., Milner, L.D. and Landmesser, L.T. (2008) Spontaneous rhythmic activity in early chick
spinal cord influences distinct motor axon pathfinding decisions. Brain Res Rev. 2008 Jan;57(1):7785.
M. GARTZ HANSON, PH.D.
(216) 262-4050  GARTZ.HANSON@GMAIL.COM  page 3
ACADEMIC FUNDING

Muscular Dystrophy Association Developmental Grant #69338

Ruth L. Kirschstein National Research Service F32 NS059267 “EXPLORING A NEW MOUSE MODEL
OF LOCOMOTOR DEVELOPMENT”
2008 to 2011

NIH R21 NS085749 Co-Investigator “THE AMELIORATION OF PEROXISOMAL DISORDERS DUE TO
DEFECTS IN PEX10” $230,175 total -final year funding -75% effort
2013 to 2015
References of Support
Lee A. Niswander
Dept. of Pediatrics
University of Colorado-Denver
Research One South (RC1-South); Room 12106
Aurora, CO 80045
(303) 724-3790
Lee.Niswander@ucdenver.edu
Lynn T. Landmesser
Arline J. & Curtis F. Garvin Professor
Dept. of Neurosciences
Case Western Reserve University
School of Medicine
Room E653 10900 Euclid Ave
Cleveland OH, 44106-4975
(216) 368-3996
ltl@case.edu
Ben A. Barres
Chair Dept of Neurobiology
Stanford University
School of Medicine
299 W. Campus Drive Sherman Fairchild Bldg. 2nd floor
Palo Alto, CA
(650) 723-3231
barres@stanford.edu
2007 to 2010
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